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打破欧美国家垄断!我国研制出系列牛用基因芯片,能让奶牛生产出优质牛奶【附基因测序技术分析】
Qian Zhan Wang· 2025-07-22 09:27
(图片来源:摄图网) 据媒体报道,近日,国家乳业技术创新中心技术研发团队成功研制出具有完全自主知识产权的奶牛种用胚胎 基因组遗传评估芯片和"高产、抗病、长生产期"功能强化基因组预测芯片。填补了我国基因芯片检测遗传评 估技术的空白,标志着中国在奶牛育种领域实现了从"跟跑"到"并跑"乃至"领跑"的关键跨越。 基因芯片是一种基于微阵列技术的高通量生物信息分析工具,能够快速检测与奶牛生产性能相关的关键功能 基因信息。此前,该技术长期被欧美发达国家垄断,国内奶牛育种依赖进口芯片,成本高昂且技术受限。此 次研发的系列基因芯片通过集成机器学习与算法模型,依托全国96座规模化牧场、60余万头奶牛的育种大数 据平台,成功解析了世界优良奶牛品种与中国区域牛群的遗传指纹,实现了从"数据积累"到"技术反超"的跨 越。 与传统全基因组测序相比,新芯片的检测效率提升4倍以上,成本仅为其1/5,而且,能够高效检测与奶牛生 产性能相关的关键功能基因信息,确保经芯片检测的奶牛能生产出"高蛋白、优脂肪、低体细胞数、低菌落 总数"的优质牛奶。不仅降低了育种成本,更通过"芯片+大数据"的闭环优化,为培育本土化高产奶牛新品系 提供了技术支撑。 基因芯 ...
华南理工林章凛等:耐酸高产赖氨酸大肠杆菌构建
合成生物学与绿色生物制造· 2025-07-11 15:57
SynBio团队 | 华南理工 林章凛教授 机制概述:酸响应模块由两个质粒构成,一个质粒带有酸响应启动子(酸触发模块),表达4个针对不同立足点开关的触发RNA,另一个质粒带有4种立足 点开关(耐酸模块),分别表达4个与耐酸有关的基因。 细节如下: 研究首先在pCOLADuet-1质粒上构建了一个由4个酸响应启动子及其下游触发RNA表达框构成的酸触发模块。4个酸响应启动子表达产物为4种针对不同立 足点开关的触发RNA。为了保证立足点开关的表达效果,研究首先对 触发RNA 和 立足点开关 进行了基于红色荧光蛋白的筛选,筛选能在低pH情况下显著 增强下游基因翻译的触发RNA-立足点开关对,并在触发RNA-立足点开关不变的情况下,从酸响应启动子文库中,筛选了不同强度的酸响应启动子。 随后将不同强度的启动子、不同的触发RNA-立足点开关对、不同的耐酸基因合并成耐酸模块文库,耐酸基因因机制差异被分为4个功能组:质子消耗系统 (gadB、gadE、adiC、ybaS 和 rcsB)、蛋白质保护系统的伴侣(hdeB、degP、dps、spy 和 DS-YlHD),细胞膜修饰和氧化还原稳态系统(sthA、 cfa、osmY 和 ...
产业年收入超60亿元,合成生物制造企业在昌平打磨“手术刀”
Xin Jing Bao· 2025-06-30 09:57
Core Insights - The article highlights the advancements in synthetic biology, particularly through gene editing technologies, which are revolutionizing the production of valuable metabolites and agricultural products, significantly impacting industries such as medicine and agriculture [1][2][5]. Group 1: Synthetic Biology and Gene Editing - The use of genetically engineered yeast to produce artemisinin has demonstrated the potential to replace the extraction from 50,000 acres of Artemisia annua cultivation, benefiting millions of malaria patients in developing countries since 2013 [1]. - Beijing Qihe Biotechnology Co., a representative company in the synthetic biology sector, has achieved a significant increase in oil content in soybeans from over 20% to above 80% through precise gene editing [2]. - The gene editing technology allows for rapid breeding cycles, reducing the time needed to develop disease-resistant traits in crops like wheat from decades to approximately three months [2][3]. Group 2: Innovation Centers and Industrialization - The Beijing Synthetic Biology Manufacturing Technology Innovation Center, established by the local government and Beijing University of Chemical Technology, serves as a core platform for technological innovation in the synthetic biology industry [4]. - The center focuses on comprehensive technological breakthroughs across the entire biological manufacturing value chain, with five research teams already operational [4][6]. - The shift from traditional petrochemical methods to biological production of materials like adipic acid is highlighted as a key step towards a greener, more sustainable industry, with significant reductions in greenhouse gas emissions [4][5]. Group 3: Industry Growth and Future Prospects - The synthetic biology sector is projected to create an economic value of $30 trillion, with an expected global production scale reaching $2 trillion to $4 trillion by 2030 [7]. - The Changping District has established a cluster of over 120 synthetic biology manufacturing companies, with projected revenues exceeding 6 billion yuan in 2024 and significant investments in fixed assets [8]. - Recent policy measures in Changping aim to support the high-quality development of the synthetic biology industry, emphasizing integrated policies and collaborative efforts across the sector [7][8].
屹唐股份:深耕晶圆加工设备 赋能全球芯片制造
Shang Hai Zheng Quan Bao· 2025-06-26 18:47
Core Viewpoint - Beijing Yitang Semiconductor Technology Co., Ltd. is a semiconductor equipment company that focuses on the research, production, and sales of integrated circuit manufacturing equipment, aiming to leverage its technological advantages and industry experience to become a trusted leader in the global semiconductor equipment field [6][8]. Company Overview - The company is headquartered in China and operates globally, providing high-performance and efficient integrated circuit equipment, including dry stripping equipment, rapid thermal processing equipment, and dry etching equipment [6][7]. - The market share of the company's dry stripping and rapid thermal processing equipment ranks among the top two globally, with its dry etching equipment being used by several well-known international integrated circuit manufacturers [6][8]. Business Performance - The company has shown continuous business growth and excellent performance, achieving a compound annual growth rate of 18.90% in net profit over the reporting period [21]. - The production capacity of the Beijing manufacturing base is projected to grow from 120 units in 2022 to 234 units in 2024 [13]. R&D and Innovation - The company has maintained a high level of R&D investment, with expenses amounting to approximately 529.85 million yuan, 608.16 million yuan, and 716.89 million yuan over the reporting period, representing 11.13%, 15.47%, and 15.47% of revenue respectively [20]. - The company has developed several new products, including the Hydrilis high-capacity vacuum wafer transfer equipment platform and advanced etching equipment, which have received high recognition from customers [24][25]. Market Position and Strategy - The company serves a wide range of clients, including the top ten global chip manufacturers and leading domestic manufacturers, covering all chip manufacturing fields [14]. - The company plans to expand its customer base and enhance market share by focusing on customer capital expenditures and product validation processes [26]. Industry Context - The semiconductor and integrated circuit industry is classified as a strategic emerging industry supported by national policies, providing a favorable environment for the company's growth [31]. - The global semiconductor market is expected to reach $1 trillion by 2030, with the integrated circuit equipment market projected to grow alongside the semiconductor industry [33]. IPO Objectives - The primary objectives of the IPO include enhancing independent innovation capabilities, consolidating market position, and improving corporate governance to share high-quality development results with investors [35][37].
琼中中平镇打造热带优稀果蔬产业园项目助农增收
Hai Nan Ri Bao· 2025-06-17 01:05
Core Viewpoint - The establishment of a tropical specialty fruit and vegetable industrial park in Qiongzhong aims to enhance farmers' income by utilizing 1,000 acres of previously idle land for the cultivation of exotic fruits and vegetables, leveraging the region's favorable climatic conditions [1][2]. Group 1: Project Overview - The industrial park features a variety of exotic fruits such as Yanzhuo fruit, golden mangosteen, high-yield oil palm, and rambutan, primarily sourced from foreign origins that are well-suited to the local climate [1][2]. - The project is focused on brand development and aims to create an organic high-end fruit brand while extending the industrial chain to achieve economic, ecological, and social benefits [1][2]. Group 2: Strategic Location and Benefits - Qiongzhong's unique geographical advantages, including low latitude and high altitude, along with its tropical rainforest climate, make it an ideal location for fruit and vegetable cultivation [2]. - The project is expected to generate an average annual income increase of 300,000 yuan for local villages, benefiting 617 impoverished households and 2,450 individuals [2]. Group 3: Future Development Plans - The project will also explore the establishment of a tropical fruit and vegetable research base, seasonal picking gardens, and shared farms, integrating agricultural production with tourism [3]. - The development strategy includes a comprehensive approach that combines production, education, research, and sales to enhance the overall agricultural efficiency and promote rural tourism [3].
农业农村部印发《关于加强农作物品种全链条管理的若干措施》
news flash· 2025-06-16 10:17
Group 1 - The article emphasizes the importance of collecting and introducing germplasm resources to enhance breeding and research capabilities [1] - It highlights the need for a regular collection of germplasm resources and accelerating the third census for cataloging and storage [1] - The introduction of high-yield, high-oil soybeans, disease-resistant corn, quality specialty wheat, sugar crops, and tropical crops is prioritized to enrich the breeding research foundation [1]
休渔不休“鱼” 江苏连云港科创融合推动渔业全链条升级
Zhong Guo Chan Ye Jing Ji Xin Xi Wang· 2025-06-13 01:03
Core Insights - The seafood market in Ganyu District, Jiangsu Province, remains vibrant despite the seasonal fishing ban, showcasing the region's efforts to activate the blue economy and establish a new high ground in marine economy [1][2] - Ganyu's seafood production reached 406,000 tons last year, with a total fishery output value exceeding 13.1 billion yuan [2][4] - The establishment of the Marine Industry Scientific Research and Innovation Center aims to enhance collaboration between academia and industry, driving innovation in the marine sector [3] Group 1: Market Dynamics - The seafood market in Ganyu is bustling with a variety of seasonal seafood available, including large crabs and shrimp, indicating strong supply and stable prices [1] - Preparations for the fishing ban included the storage of 100,000 jin (50 tons) of crabs and the establishment of temporary holding pools for shrimp to ensure market supply during the ban [1] Group 2: Industry Development - Ganyu District has a coastline of 62.5 kilometers and a marine farming area of 1.725 million acres, producing over 60 types of seafood [2] - The district has established a marine industry technology innovation alliance, comprising 45 member units, to foster collaborative innovation and support the development of marine industries [2][3] Group 3: Technological Innovation - The district focuses on a comprehensive "fish, shrimp, crab, shellfish, and algae" industry system, promoting technological innovation to enhance competitiveness [4] - Key technological breakthroughs have been achieved in areas such as salmon aquaculture and intelligent ecological farming, addressing common challenges in the industry [4] - The introduction of new oyster varieties is expected to significantly increase farmers' income, with projections of an additional 6 million yuan in revenue [4]
中国技术持续助力共建“一带一路”国家产业发展
Huan Qiu Shi Bao· 2025-06-12 07:52
Group 1 - The second "Belt and Road" Technology Exchange Conference was held in Chengdu, Sichuan, focusing on building a technology innovation community among participating countries [2][3] - Chinese technology is increasingly becoming a driving force for industrial upgrades in "Belt and Road" countries, enhancing local industry development [2] - Collaboration between Chinese high-tech enterprises and local companies in Belarus is taking place in fields such as new energy, machinery, big data, artificial intelligence, and industrial internet [2] Group 2 - Qingdao Jicheng Electronics Co., Ltd. plans to localize water meter production in Saudi Arabia, significantly improving water resource management efficiency [2][3] - The conference announced the establishment of the Chengdu-Chongqing "Belt and Road" International Technology Transfer Center, aiming to create over 100 international cooperation projects within three years [5] - The "Double Thousand" plan aims to implement 1,000 technology exchange cooperation projects and support 1,000 young scientists' exchanges by 2030 [5] Group 3 - The focus of international cooperation is shifting from traditional product trade to the output of key intermediates, production capacity, supply chains, and standard management [5] - This transformation is expected to enhance international cooperation efficiency and lower collaboration barriers, aiding in the cultivation of localized brands in "Belt and Road" countries [5]
Rayonier Advanced Materials (RYAM) FY Earnings Call Presentation
2025-06-11 13:40
Investor Presentation Second Quarter Equity Conferences Regulatory and Environmental Risks The Company's business is subject to extensive environmental laws, regulations and permits that may materially restrict or adversely affect how the Company conducts business and its financial results. The potential long-term impact of climate-related risks remain uncertain at this time. Regulatory measures to address climate change may materially restrict how the Company conducts business or adversely affect its finan ...
京津冀协同,聚力种业振兴!中国北京种业大会将9月11日开幕
Nan Fang Nong Cun Bao· 2025-06-11 09:33
Core Viewpoint - The 32nd China Beijing Seed Industry Conference will be held from September 11 to 14, 2023, focusing on "deepening regional collaboration and promoting seed industry revitalization" with an emphasis on regionalization, internationalization, and marketization [3][4]. Group 1: Conference Objectives and Themes - The conference aims to enhance agricultural regional collaboration in the Beijing-Tianjin-Hebei area, leverage global resources, and promote agricultural technology achievements to ensure food security and build a strong agricultural nation [4][6]. - This year's conference marks a significant transition from a three-year foundational phase to a five-year effectiveness phase in seed industry revitalization [7]. Group 2: Innovation and Development - Beijing has established itself as a leader in seed industry innovation, with significant achievements such as the world's largest DNA fingerprinting database for watermelon and corn, and leading breeding technologies for various species [6][7]. - The conference will feature a "1+7" distributed meeting model, with the main venue in Tongzhou and seven sub-venues across different districts, showcasing over a thousand breakthrough varieties of corn and vegetables [14][16]. Group 3: International Collaboration - The conference will promote international exchanges and transactions in the seed industry, highlighting Beijing's global footprint in seed development and technology transfer [9][10]. - Initiatives include partnerships with countries along the Belt and Road, focusing on the international transformation of domestic agricultural achievements [12]. Group 4: Activities and Engagement - A series of activities under the "1+1+1+10+N" framework will be organized, including technology showcases, competitions, and forums to facilitate industry collaboration and innovation [13][15]. - The event will also feature ten specialized forums focusing on various agricultural sectors, enhancing regional industry advantages and promoting technology integration [17].