证 券 研 究 报 告 加科思-B（01167.HK）深度研究报告 强推（首次） pan-KRAS 抑制剂价值重估空间大 [主要财务指标 Indicator_FinchinaSimpleHK] | | 2024A | 2025E | 2026E | 2027E | | --- | --- | --- | --- | --- | | 营业总收入(百万元) | 156 | 234 | 627 | 508 | | 同比增速(%) | 145.1% | 50.5% | 167.6% | -19.1% | | 归母净利润(百万元) | -156 | -15 | 313 | 192 | | 同比增速(%) | 56.6% | 90.7% | 2,258.6% | -38.6% | | 每股盈利(元) | -0.20 | -0.02 | 0.40 | 0.24 | | 市盈率(倍) | -29 | -308 | 14 | 23 | | 市净率(倍) | 4.8 | 4.9 | 3.7 | 3.2 | 资料来源：公司公告，华创证券预测 注：股价为 2026 年 2 月 23 日收盘价 港股公司 生物医药Ⅲ 2026 年 02 ...

证 券 研 究 报 告 资料来源：公司公告，华创证券预测 注：股价为 2026 年 2 月 23 日收盘价 港股公司 生物医药Ⅲ 2026 年 02 月 24 日 目标价：11.26 港元 当前价：6.37 港元 华创证券研究所 证券分析师：刘浩 邮箱：liuhao@hcyjs.com 执业编号：S0360520120002 加科思-B（01167.HK）深度研究报告 强推（首次） pan-KRAS 抑制剂价值重估空间大 [主要财务指标 Indicator_FinchinaSimpleHK] | | 2024A | 2025E | 2026E | 2027E | | --- | --- | --- | --- | --- | | 营业总收入(百万元) | 156 | 234 | 627 | 508 | | 同比增速(%) | 145.1% | 50.5% | 167.6% | -19.1% | | 归母净利润(百万元) | -156 | -15 | 313 | 192 | | 同比增速(%) | 56.6% | 90.7% | 2,258.6% | -38.6% | | 每股盈利(元) | -0.20 | - ...

Investment Rating - The investment rating for the pharmaceutical and biotechnology industry is "Positive" and the rating has been maintained [2] Core Views - The pharmaceutical and biotechnology industry index increased by 3.08%, ranking third among 31 primary industries, outperforming the CSI 300 index which rose by 0.94% [5][17] - The report highlights the acceleration of internationalization of innovative drugs, with a focus on two main directions: the global multi-center clinical capabilities and differentiated technology platforms, as well as short-term opportunities driven by ASCO data [8][9] Industry Performance - The valuation of the pharmaceutical and biotechnology industry as of May 23, 2025, is a PE (TTM overall method, excluding negative values) of 27.60x, up from 26.77x in the previous period, indicating an upward trend but still below the average [22] - The top three sub-industries in terms of PE are vaccines (52.08x), hospitals (37.38x), and medical devices (33.40x), while the lowest valuation is in pharmaceutical circulation (15.18x) [22] Important Industry News - The CDE released guidelines for clinical trials of Alzheimer's disease drugs to provide technical standards for scientific research and evaluation [27] - AbbVie’s c-Met ADC "Teliso-V" received FDA approval, marking it as the first of its kind globally [28] - The report mentions significant collaborations, such as Pfizer's partnership with 3SBio for a PD-1/VEGF bispecific antibody, valued at over $6 billion [8][51] Company Dynamics - Hengrui Medicine officially listed on the Hong Kong Stock Exchange with an IPO price of HKD 44.05 per share, achieving a market capitalization of over HKD 290 billion [44][45] - The report notes that 35 listed companies in the pharmaceutical and biotechnology sector experienced a net reduction in shareholder holdings amounting to CNY 1.336 billion during the reporting period [5]