公司评论 第一上海研究部 research@firstshanghai.com.hk 2026 年 1 月 27 日 【公司评论】 但玉翠 852 2532 1539 tracy.dan@firstshanghai.com.hk 管理团队介绍 加科思的核心管理团队以创始人王印祥博士为核心，王印祥博士于 1999 年获得美国 阿肯色大学医学院生物化学及分子生物学博士学位，耶鲁大学的 Koleske 实验室分子 生物物理和生物化学系完成了博士后研究。2003 年 1 月共同创立了浙江贝达药业有 限公司，是贝达药业的创始人之一。王博拥有 20 多年小分子抗肿瘤药研发经验，曾 主导中国第一款靶向抗肿瘤药埃克替尼（凯美纳）的研发与上市。加科思目前管理团 队一半来自贝达药业，另一半为公司成立后引入的来自大药企和顶尖医院的各类人 才。25 年 11 月为推进全球化战略引入了联席首席执行官（Co-CEO）制度，联席 CEO、首席医学官(CMO) 王宜 (Andrea Wang-Gillam) 博士 20 年 7 月加入加科思，在 美国有 20 余年肿瘤医生经验，她在圣路易斯华盛顿大学医学中心担任肿瘤科副教 授，并曾兼任消化道 ...

Group 1 - Pharmaceutical stocks experienced a significant rise in early trading, with notable increases in share prices [1][3] - 加科思-B (01167) saw an increase of 8.71%, reaching HKD 7.24 [1][3] - 和铂医药-B (02142) rose by 7.39%, trading at HKD 14.25 [1][3] - 复宏汉霖 (02696) increased by 4.46%, with a price of HKD 66.70 [1][3] - 映恩生物-B (09606) experienced a rise of 2.98%, priced at HKD 359 [1][3]

Core Viewpoint - Pharmaceutical stocks have risen significantly, driven by regulatory changes aimed at expediting the approval of urgently needed foreign drugs in China [1] Group 1: Stock Performance - Companies such as 加科思-B (01167) increased by 8.71% to HKD 7.24, 和铂医药-B (02142) rose by 7.61% to HKD 14.28, 复宏汉霖 (02696) gained 5.25% to HKD 67.2, and 映恩生物-B (09606) climbed 4.88% to HKD 365.6 [1] Group 2: Regulatory Changes - The National Medical Products Administration (NMPA) has optimized the review and approval process for urgently needed foreign drugs that are already on the market, aiming to meet the clinical needs of patients [1] - The NMPA emphasizes a clinical value-oriented approach, encouraging applicants to conduct global synchronous research and simultaneous submissions in China [1] - Original and generic drugs that are urgently needed and meet the criteria can be included in the priority review and approval category [1] Group 3: Market Outlook - Huatai Securities believes that the valuation of innovative drugs in the Hong Kong market remains attractive compared to global peers, attributing the liquidity discount to the decline in innovative drugs during November and December [1] - The firm anticipates that the ongoing liquidity recovery, along with continued business development (BD) activities and the upcoming JPM conference and annual report season, will boost the innovative drug sector [1] - The upward trend in the innovative drug sector is expected to continue as liquidity improves at the beginning of the year [1]

Core Viewpoint - The pharmaceutical stocks have risen significantly, driven by regulatory changes from the National Medical Products Administration (NMPA) aimed at expediting the approval of urgently needed foreign drugs in China [1] Group 1: Stock Performance - Stocks such as Akeso-B (01167) increased by 8.71% to HKD 7.24, HAPO (02142) rose by 7.61% to HKD 14.28, Innovent Biologics (02696) gained 5.25% to HKD 67.2, and InnoCare Pharma-B (09606) climbed 4.88% to HKD 365.6 [1] Group 2: Regulatory Changes - On January 7, the NMPA announced measures to optimize the review and approval process for urgently needed foreign drugs already on the market, aiming to meet the clinical needs of patients [1] - The NMPA emphasized a clinical value-oriented approach, encouraging applicants to conduct global synchronized research and simultaneous submissions for market approval in China [1] - The NMPA will prioritize the review of urgently needed foreign original and generic drugs that meet specific criteria [1] Group 3: Market Outlook - Huatai Securities believes that the valuation of innovative drugs in the Hong Kong market remains attractive compared to global peers, attributing the recent decline in innovative drug stocks to liquidity discounts [1] - The firm anticipates that the ongoing liquidity recovery, along with external business development (BD) activities, the JPMorgan Healthcare Conference, and the annual report cycle, will boost the innovative drug sector's performance [1] - The upward trend in the innovative drug sector is expected to continue as liquidity improves [1]

Group 1 - The company, 加科思-B (01167), announced a share buyback plan [1] - The total expenditure for the buyback is HKD 1.4846 million [1] - The company will repurchase 240,000 shares at a price range of HKD 6.13 to HKD 6.21 per share [1]

Core Viewpoint - The company, 加科思-B (01167.HK), announced a share buyback on January 6, 2026, involving an expenditure of HKD 1.485 million to repurchase 240,000 shares at a price range of HKD 6.13 to HKD 6.21 per share [1]. Group 1 - The total expenditure for the share buyback is HKD 1.485 million [1]. - The number of shares repurchased is 240,000 [1]. - The buyback price per share ranges from HKD 6.13 to HKD 6.21 [1].

Core Viewpoint - The company, 加科思-B (01167), announced a share buyback plan, indicating confidence in its stock value and future prospects [1] Group 1 - The company will repurchase 240,000 shares at a total cost of HKD 1.4846 million [1] - The buyback price per share ranges from HKD 6.13 to HKD 6.21 [1] - The buyback is scheduled to take place on January 6, 2026 [1]

FF305 翌日披露報表 (股份發行人 ── 已發行股份或庫存股份變動、股份購回及/或在場内出售庫存股份) 表格類別： 股票 狀態： 新提交 公司名稱： 加科思藥業集團有限公司 呈交日期： 2026年1月6日 如上市發行人的已發行股份或庫存股份出現變動而須根據《香港聯合交易所有限公司（「香港聯交所」）證券上市規則》(「《主板上市規則》」)第13.25A條 / 《香港聯合交易所有限公司GEM證券 上市規則》(「《GEM上市規則》」)第17.27A條作出披露，必須填妥第一章節 。 | 第一章節 | | | | | | | | --- | --- | --- | --- | --- | --- | --- | | 1. 股份分類 | 普通股 | 股份類別 | 不適用 | 於香港聯交所上市 | 是 | | | 證券代號 (如上市) | 01167 | 說明 | | | | | | A. 已發行股份或庫存股份變動 | | | | | | | | | | 已發行股份（不包括庫存股份）變動 | | 庫存股份變動 | 每股發行/出售價 (註4) | 已發行股份總數 | | | 事件 | 已發行股份（不包括庫存股份）數 目 | ...

股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 | 1. 股份分類 | 普通股 | 股份類別 | 不適用 | | 於香港聯交所上市 (註1) | | 是 | | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 01167 | 說明 | | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | | 法定/註冊股本 | | | 上月底結存 | | | 1,000,000,000 | USD | | 0.0001 USD | | | 100,000 | | 增加 / 減少 (-) | | | 0 | | | USD | | | 0 | | 本月底結存 | | | 1,000,000,000 | USD | | 0.0001 USD | | | 100,000 | 本月底法定/註冊股本總額： USD 100,000 截至月份: 2025年12月31日 狀態: 新提交 致：香港交易及結算所有限公司 公司名稱: 加科思藥業集團有限公司 呈交日期: 202 ...

Core Insights - The innovative drug sector is experiencing a significant bull market, with the entry threshold for top-performing stocks raised considerably [1] - In 2024, the median stock price increase for the top 10 innovative drug companies was 57.9%, while in 2025, this surged to a median increase of 495.41%, with the highest increase reaching 1824% [2] Group 1: Top Performing Companies - The top-performing stock in 2025 was Beihai Kangcheng, with an astonishing annual increase of 1824%, surprising many in the market [4] - Following Beihai Kangcheng, the second highest was Sanleaf Biotech, which saw an increase of 870%, despite facing significant operational challenges [10] - Yaojie Ankang ranked third with a 773% increase, although its valuation raised concerns due to its limited clinical progress [12] - Heber Pharmaceuticals achieved a 553% increase, driven by its dual-engine model of R&D and business development [16] - Xuan Bamboo Biotech, a newly listed company, experienced a 507% increase, attributed to its new stock status and positive clinical data [20] Group 2: Market Dynamics and Trends - The market has seen a trend of speculative trading, with some companies experiencing price surges not necessarily backed by fundamental improvements [4] - The rise of companies like Heber Pharmaceuticals and Rongchang Biotech illustrates that long-term undervalued firms can achieve significant valuation recovery through continuous R&D and commercialization breakthroughs [4][30] - The innovative drug sector's growth is heavily influenced by liquidity and market sentiment, with many price increases based on speculative expectations rather than solid fundamentals [39] Group 3: Company-Specific Developments - Beihai Kangcheng's stock price recovery was linked to strategic capital injections, resolving its cash flow crisis [7] - Sanleaf Biotech's stock price rebound was primarily driven by its RSV vaccine pipeline, despite facing significant financial pressures [10][11] - Yaojie Ankang's rapid valuation increase raised questions about its sustainability, given its limited clinical advancements [13][14] - Heber Pharmaceuticals' growth was supported by strategic partnerships and a robust technology platform, enhancing investor confidence [18][19] - Rongchang Biotech's stock performance was bolstered by successful product approvals and strategic financing, improving its market outlook [31]