Core Insights - Bristol Myers Squibb (BMY) reported strong Q2 2025 results, with GAAP revenue of $12.269 billion exceeding analyst estimates of $11.385 billion and non-GAAP EPS of $1.46 surpassing the expected $1.07 per share [1][2] - Despite the revenue beat, year-over-year performance was impacted by declines in legacy drugs, margin compression, and significant R&D expenses, leading to a revision in non-GAAP EPS guidance [1][11] Financial Performance - Q2 2025 non-GAAP EPS was $1.46, down 29.5% from $2.07 in Q2 2024 [2] - GAAP EPS was $0.64, a decrease of 22.9% from $0.83 in Q2 2024 [2] - Revenue for Q2 2025 was $12.3 billion, a slight increase of 0.8% from $12.2 billion in Q2 2024 [2] - Non-GAAP gross margin narrowed to 72.6% from 75.6% year-over-year, while operating margin decreased to 40.4% from 41.1% [2][7] Product Performance - The Growth Portfolio generated $6.6 billion in sales for Q2 2025, an 18% increase, driven by immuno-oncology products and new therapies [5] - Breyanzi revenue surged 125%, Camzyos increased by 86%, and Reblozyl rose by 33% in Q2 2025 [5][6] - The Legacy Portfolio saw a 14% decline, with Revlimid down 38%, Pomalyst/Imnovid down 26%, and Sprycel down 72% year-over-year [6] Strategic Focus - The company is focused on building its "Growth Portfolio" through new product launches and global expansion while managing declines from older drugs [4] - A significant $1.5 billion R&D charge related to a partnership with BioNTech impacted EPS guidance [9][11] - The company raised its fiscal 2025 non-GAAP revenue outlook to $46.5 billion to $47.5 billion but lowered non-GAAP EPS guidance to $6.35–$6.65 due to the BioNTech charge [11] Pipeline and Development - Progress was made in the drug pipeline, with new indications for Sotyktu and label updates for Breyanzi [10] - Opdivo received European approval for a new subcutaneous form, and the company launched initiatives to improve access to Eliquis [10] - The company is actively pursuing strategic partnerships and business development opportunities to enhance its pipeline [10]

Core Insights - Bristol Myers Squibb (BMY) reported $12.27 billion in revenue for Q2 2025, a year-over-year increase of 0.6% and a surprise of +7.67% over the Zacks Consensus Estimate of $11.4 billion [1] - The EPS for the same period was $1.46, down from $2.07 a year ago, with a surprise of +36.45% compared to the consensus estimate of $1.07 [1] Revenue Performance - Net sales for Cobenfy were $35 million, exceeding the estimated $28.25 million [4] - Opdivo's U.S. net sales reached $1.51 billion, surpassing the $1.38 billion estimate, reflecting a +7.1% year-over-year change [4] - Pomalyst/Imnovid's U.S. net sales were $584 million, below the $627.82 million estimate, showing an -18.4% year-over-year decline [4] - International net sales for Pomalyst/Imnovid were $124 million, exceeding the $95.34 million estimate, but down -49% year-over-year [4] - Revlimid's net sales were $838 million, above the $625.54 million estimate, representing a -38.1% year-over-year decline [4] - Opdivo's total net sales were $2.56 billion, exceeding the $2.4 billion estimate, with a +7.3% year-over-year increase [4] - Abraxane's net sales were $105 million, slightly above the $102.66 million estimate, but down -54.6% year-over-year [4] - Reblozyl's net sales reached $568 million, surpassing the $546.45 million estimate, with a +33.7% year-over-year increase [4] - Zeposia's net sales were $150 million, exceeding the $129.3 million estimate, but down -0.7% year-over-year [4] - Breyanzi's net sales were $344 million, above the $299.75 million estimate, reflecting a +124.8% year-over-year increase [4] - Abecma's net sales were $87 million, below the $99.76 million estimate, showing an -8.4% year-over-year decline [4] - Opdualag's net sales reached $284 million, exceeding the $276.44 million estimate, with a +20.9% year-over-year increase [4] Stock Performance - Bristol Myers' shares have returned -3.5% over the past month, compared to the Zacks S&P 500 composite's +2.7% change [3] - The stock currently holds a Zacks Rank 4 (Sell), indicating potential underperformance relative to the broader market in the near term [3]

Core Insights - Bristol Myers Squibb (BMY) reported $11.2 billion in revenue for Q1 2025, a year-over-year decline of 5.6%, but exceeded the Zacks Consensus Estimate by 4.38% [1] - The company achieved an EPS of $1.80, a significant improvement from -$4.40 a year ago, with a surprise of 19.21% over the consensus estimate of $1.51 [1] Financial Performance - Net Sales for Abraxane in the U.S. were $40 million, significantly below the estimated $66.06 million, representing a decline of 72.4% year-over-year [4] - Opdivo's U.S. sales reached $1.33 billion, surpassing the $1.19 billion estimate, with a year-over-year increase of 15.3% [4] - Pomalyst/Imnovid's U.S. sales were $537 million, below the estimated $588.85 million, reflecting a decline of 10.1% year-over-year [4] - International sales for Pomalyst/Imnovid were $122 million, slightly above the estimate of $118.98 million, but down 54.5% year-over-year [4] - Revlimid's sales were $936 million, exceeding the $884.91 million estimate, with a year-over-year decline of 43.9% [4] - Opdivo's total sales reached $2.27 billion, above the $2.17 billion estimate, with a year-over-year increase of 9% [4] - Abraxane's total sales were $105 million, below the estimated $125.23 million, reflecting a decline of 51.6% year-over-year [4] - Reblozyl's sales were $478 million, slightly above the estimate of $477.54 million, with a year-over-year increase of 35% [4] - Zeposia's sales were $107 million, below the estimated $119.29 million, representing a decline of 2.7% year-over-year [4] - Breyanzi's sales reached $263 million, exceeding the estimate of $240.29 million, with a year-over-year increase of 145.8% [4] - Abecma's sales were $103 million, above the estimated $97.70 million, reflecting a year-over-year increase of 25.6% [4] - Opdualag's sales were $252 million, slightly below the estimate of $261.59 million, with a year-over-year increase of 22.3% [4] Stock Performance - Bristol Myers' shares have returned -18% over the past month, compared to the Zacks S&P 500 composite's -5.1% change [3] - The stock currently holds a Zacks Rank 3 (Hold), indicating potential performance in line with the broader market in the near term [3]

Core Viewpoint - Bristol Myers Squibb (BMY) is expected to report a significant increase in quarterly earnings per share, while revenues are projected to decline year-over-year [1]. Financial Projections - Analysts predict quarterly earnings of $1.54 per share, reflecting a 135% increase compared to the same period last year [1]. - Revenues are forecasted to be $10.74 billion, representing a year-over-year decrease of 9.5% [1]. - The consensus EPS estimate has been adjusted upward by 0.8% over the past 30 days, indicating a reassessment of initial projections by analysts [2]. Key Metrics Estimates - Net Sales for Recent LOE Products - Revlimid is estimated at $879.35 million, indicating a change of -47.3% from the prior-year quarter [5]. - Net Sales for In-Line Products - Opdivo is expected to reach $2.18 billion, reflecting a year-over-year change of +4.9% [5]. - Net Sales for Recent LOE Products - Abraxane is projected at $127.62 million, showing a change of -41.2% from the year-ago quarter [6]. - Net Sales for New Product Portfolio - Reblozyl is estimated at $483.40 million, indicating a change of +36.6% year-over-year [6]. - Net Sales for Recent LOE Products - Abraxane (U.S.) is expected to be $66.33 million, reflecting a year-over-year change of -54.3% [7]. - Net Sales for In-Line Products - Opdivo (U.S.) is projected at $1.19 billion, indicating a year-over-year change of +3.4% [7]. - Net Sales for In-Line Products - Pomalyst/Imnovid (U.S.) is expected to reach $582.15 million, reflecting a change of -2.5% from the prior-year quarter [8]. - Net Sales for Recent LOE Products - Revlimid (U.S.) is estimated at $706.32 million, indicating a change of -51.4% from the prior-year quarter [9]. - Net Sales for New Product Portfolio - Reblozyl (U.S.) is projected at $392.41 million, reflecting a change of +33.9% from the prior-year quarter [10]. Market Performance - Over the past month, Bristol Myers shares have recorded returns of -18.5%, compared to the Zacks S&P 500 composite's -6.9% change [10]. - Based on its Zacks Rank 3 (Hold), BMY is expected to perform in line with the overall market in the upcoming period [10].