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Amgen Buys Dark Blue Therapeutics to Strengthen Oncology Pipeline
ZACKS· 2026-01-07 14:35
Key Takeaways Amgen acquired Dark Blue Therapeutics for about $840M, strengthening its oncology pipeline.AMGN gains a preclinical small-molecule degrader targeting MLLT1/3 proteins tied to certain AML types.Amgen has no marketed AML therapy, but sells Blincyto for ALL and has early AML bispecifics.Amgen (AMGN) announced that it has acquired U.K.-based private biotech company, Dark Blue Therapeutics, for approximately $840 million.The acquisition will strengthen Amgen’s oncology pipeline by adding Dark Blue’ ...
Can BMY's Growth Portfolio Drive Top-Line Expansion in 2026?
ZACKS· 2025-12-31 13:35
Key Takeaways BMY's growth portfolio rose 17% in the first nine months, while legacy drug sales fell 16% on generics.BMY's Opdivo momentum and Qvantig approval support projected high single- to low double-digit growth.BMY's Reblozyl topped a $2B run rate, Breyanzi passed $1B, while legacy drugs still made up 47% of sales.Bristol Myers Squibb’s (BMY) performance in 2025 reflects an ongoing transition in its revenue base, with growth from newer products partially offsetting continued declines in legacy drugs. ...
高盛上调百时美施贵宝(BMY.US)目标价至57美元,强调其风险回报平衡
智通财经网· 2025-12-31 03:52
- "传统"产品则濒临或已失去专利独占。 两大阵营均有重磅品种坐镇:增长阵营由抗癌药Opdivo领衔,传统阵营则由Eliquis撑盘,尽管后者面临 日益激烈的竞争压力。近期,增量重任主要落在增长类药物肩上——第三季度该板块销售额同比增长 18%,达69亿美元,不仅抵消了传统产品12%的同比下滑,更推动公司总收入增长3%至122亿美元。 智通财经APP获悉,高盛把百时美施贵宝(BMY.US)目标价从 51 美元上调至 57 美元,评级维持"中 性"。该行表示,百时美施贵宝在风险与回报之间展现出一种审慎权衡的平衡:股息率 4.6%,派息率约 85%,即便压力增大,仍留有一定空间支撑股息。 当前,专利悬崖风险已成市场共识。为应对挑战,管理层通过系列收购强化研发管线,并将风险分散至 更多靶点市场——此策略虽非"万能解药",却在关键节点夯实了企业抗风险能力,通过多元化布局提升 战略纵深,为穿越行业周期提供了更坚实的支撑。 百时美施贵宝专注于心血管、免疫与肿瘤药物的研发与商业化,其产品线被划分为两类: - "增长"药物仍有数年专利护航; 据了解,百时美施贵宝继续定位为一家全球性生物制药公司,致力于发现、开发和交付创新药物 ...
Goldman Sachs Raises Bristol-Myers (BMY) Target, Keeps Neutral Rating
Yahoo Finance· 2025-12-30 22:55
Bristol-Myers Squibb Company (NYSE:BMY) is included among the 14 Best Pharma Dividend Stocks to Buy in 2026. Goldman Sachs Raises Bristol-Myers (BMY) Target, Keeps Neutral Rating On December 15, Goldman Sachs raised the firm’s price target on Bristol-Myers Squibb Company (NYSE:BMY) to $57 from $51 and kept a Neutral rating on the shares. Bristol-Myers Squibb Company (NYSE:BMY) presents a measured balance between risk and reward. The stock offers a 4.6% dividend yield, and the payout ratio sits near 85%. ...
BMY vs AMGN: Which Biotech Stock Is More Resilient Now?
ZACKS· 2025-12-30 19:26
Core Insights - Bristol Myers Squibb (BMY) and Amgen (AMGN) are leading global biotechnology companies with diverse portfolios focused on various therapeutic areas [1][2] - Both companies have established strong market positions and consistently delivered shareholder value, making stock selection challenging [3] BMY Overview - BMY's growth portfolio includes drugs such as Opdivo, Reblozyl, and Breyanzi, contributing to strong top-line growth [4][10] - Opdivo sales are driven by its launch in MSI-high colorectal cancer and growth in non-small cell lung cancer, with global sales expected to increase in the high single-digit to low double-digit range by 2025 [5][6] - Reblozyl has annualized sales exceeding $2 billion, significantly boosting BMY's revenue, while Breyanzi sales are also strong, annualizing over $1 billion [7][8] - BMY's legacy portfolio is facing challenges due to generic competition, with expected declines of 15-17% in 2025 [11][12] AMGN Overview - Amgen has a vast portfolio with strong positions in oncology, cardiovascular disease, and rare diseases, supported by growth products like Repatha and Tezspire [13][14] - Despite competitive pressures affecting some products, Amgen's growth trajectory is driven by key drugs and a robust pipeline [15] - The acquisition of Horizon Therapeutics has expanded Amgen's rare disease offerings, enhancing its market position [16] Financial Estimates - BMY's 2025 sales are estimated to decrease by 0.8%, while EPS is expected to increase by 466.09% [17] - AMGN's 2025 sales are projected to grow by 8.78%, with EPS improving by 7.26% [20] Price Performance and Valuation - Over the past six months, BMY has outperformed AMGN slightly, with gains of 13.9% compared to AMGN's 13.5% [21] - In terms of valuation, AMGN trades at a higher forward P/E of 15.2X compared to BMY's 8.99X, indicating a more expensive valuation [21] - BMY offers a higher dividend yield of 4.54% compared to AMGN's 2.86% [22] Investment Considerations - Both companies are considered safe investments in the biotech sector, but AMGN is currently viewed as a better pick due to solid fundamentals and positive estimate revisions [23][25]
Is Bristol Myers Squibb a Buy, Sell, or Hold in 2026?
Yahoo Finance· 2025-12-30 16:05
Key Points Bristol Myers Squibb's financial results haven't been great in recent years. The giant drugmaker has been facing challenges, including several patent cliffs. New launches, pipeline progress, and a dividend program still make it attractive. 10 stocks we like better than Bristol Myers Squibb › The past five years have been challenging for Bristol Myers Squibb (NYSE: BMY). The company lost patent exclusivity for some key products, including one that was once its best-selling medicine, can ...
Got $500? 3 Dividend-Paying Healthcare Stocks to Buy and Hold Forever
Yahoo Finance· 2025-12-30 14:35
Key Points Bristol Myers Squibb is a pharmaceutical giant with a solid dividend history. Medtronic is a high-yield medical device maker that's nearing Dividend King status. J&J makes drugs and medical devices and boasts of over 50 annual dividend increases. 10 stocks we like better than Bristol Myers Squibb › Most dividend investors are looking not just for a high yield, but also for a company that can reliably support that yield over the long term. It is harder to find than you may think, but n ...
Can J&J's Pipeline Progress in 2025 Aid Long-Term Growth?
ZACKS· 2025-12-26 14:26
Core Insights - Johnson & Johnson (J&J) has a strong R&D pipeline focused on immunology, oncology, and neuroscience, with significant advancements in 2025 [1][2][8] Pipeline and Product Approvals - J&J has achieved major clinical and regulatory milestones, including approvals for Inlexzoh/TAR-200 for high-risk non-muscle invasive bladder cancer and Imaavy (nipocalimab) for generalized myasthenia gravis [2][11] - Nipocalimab is being evaluated for various immune-mediated conditions and is considered to have pipeline-in-a-product potential [3] - Regulatory applications for icotrokinra, an oral treatment for moderate-to-severe plaque psoriasis, have been filed in the US and EU [4] - J&J's new cancer drugs, including Carvykti, Tecvayli, and Talvey, generated $2.14 billion in sales in the first nine months of 2025 [5][11] Strategic Acquisitions and Expansions - The acquisition of Intra-Cellular Therapies added Caplyta, an antidepressant, to J&J's neuroscience portfolio [6] - J&J aims to expand the indications of currently marketed products, with recent approvals for Tremfya, Rybrevant, and Caplyta [7] Long-term Growth Potential - J&J's pipeline execution and recent product approvals position the company for sustained growth beyond short-term pressures, with multiple late-stage assets and significant sales potential across its Innovative Medicine portfolio [8] Competitive Landscape - J&J faces competition in the oncology space from major players like Pfizer, AstraZeneca, Merck, and Bristol-Myers, each with strong oncology portfolios and growth in sales [9][10][12][13][14] Financial Performance and Valuation - J&J's shares have outperformed the industry, rising 42.8% over the past year compared to a 17.5% increase for the industry [15] - The company's shares trade at a price/earnings ratio of 18.09, slightly above the industry average of 17.59 and its five-year mean of 15.65 [18] - The Zacks Consensus Estimate for 2025 earnings has increased from $10.86 to $10.87 per share, indicating positive earnings revisions [20]
PFE's Oncology & Obesity Pipeline Position It for Post-LOE Growth
ZACKS· 2025-12-24 17:21
Core Insights - Pfizer anticipates a significant revenue decline due to the loss of exclusivity for key products between 2026 and 2030, including Eliquis, Vyndaqel, Ibrance, Xeljanz, and Xtandi, all facing patent expirations [1][9] - The company has bolstered its R&D pipeline through mergers and acquisitions, successful data readouts, and pivotal program initiations, positioning itself for sustainable growth post-LOE [1][7] Oncology Pipeline - Pfizer has advanced its oncology pipeline with several candidates in late-stage development, including vepdegestrant for ER+/HER2- metastatic breast cancer, atirmociclib for HR+/HER2- metastatic breast cancer, and sigvotatug vedotin for metastatic non-small cell lung cancer [2] - By 2030, Pfizer expects to have eight or more blockbuster oncology medicines in its portfolio [4] Non-Oncology Developments - In non-oncology areas, Pfizer is developing an mRNA flu/COVID combination vaccine and osivelotor for sickle cell disease, both in late-stage development [4] - The company is also expanding the labels of approved products like Padcev, which was recently approved by the FDA in combination with Merck's Keytruda for specific bladder cancer patients [5] Obesity Market Expansion - Pfizer is strengthening its presence in the obesity market, currently dominated by Eli Lilly and Novo Nordisk, through the $10 billion acquisition of Metsera and the in-licensing of YP05002, an oral GLP-1 receptor agonist [6] - The Metsera acquisition added four novel clinical-stage programs for obesity, expected to generate billions in peak sales [6] Competitive Landscape - Pfizer faces revenue headwinds from patent expirations but is positioned for long-term growth through its expanding late-stage pipeline in oncology and investments in obesity, vaccines, and rare diseases [7] - The oncology market is competitive, with major players like AstraZeneca, Merck, Johnson & Johnson, and Bristol-Myers also focusing on oncology sales [10][11][12][13] Financial Performance - Pfizer's stock has declined 7% over the past year, while the industry has seen a 16% increase [14] - The company's shares are trading at a forward price/earnings ratio of 8.18, below the industry average of 17.40 and its own 5-year mean of 10.39, indicating attractive valuation [16] - The Zacks Consensus Estimate for 2025 earnings has increased slightly to $3.10 per share, while the estimate for 2026 has decreased to $3.04 per share [18]
Will the Recent Pricing Deal With the Government Impact BMY's Sales?
ZACKS· 2025-12-23 20:11
Key Takeaways BMY will give Eliquis free to Medicaid and donate more than 7 tons of its active ingredient. Eliquis is Bristol Myers Squibb's top drug, posting $11B in sales in the first nine months of 2025. The government deal grants BMY three years of tariff relief and no future pricing mandates.Bristol Myers Squibb (BMY) announced a pricing agreement with the U.S. government to supply Eliquis (apixaban) at no cost to Medicaid beginning Jan. 1, 2026. BMY will also donate more than 7 tons of the active phar ...