Core Viewpoint - China Pharmaceutical University has announced procurement intentions for 26 items of laboratory equipment, with a total budget of 114 million yuan, scheduled for procurement between June and November 2025 [2][3]. Group 1: Procurement Overview - The procurement includes advanced biomedical research equipment such as small animal 3D optical imaging systems, small animal in vivo cell dynamic analysis imaging, small animal irradiation devices, and small animal MRI systems [3][4][6]. - The total budget for the procurement is 114 million yuan, indicating significant investment in research capabilities [2][3]. Group 2: Specific Equipment Details - **Small Animal 3D Optical Imaging System**: This device allows non-invasive, real-time 3D imaging of small experimental animals, widely used in oncology, immunology, and drug development [4]. - **Small Animal Irradiation Device**: Designed for precise radiation exposure of cells and small animals, applicable in cancer biology and stem cell research [5]. - **Small Animal MRI System**: Provides high-resolution imaging for observing structural and functional changes in small animals, crucial for biomedical research [6]. Group 3: Research and Development Impact - The procurement aims to enhance the university's research capabilities in various fields, including drug development, cancer research, and molecular biology [4][5][6]. - The investment reflects the university's commitment to advancing biomedical research and its role as a leader in pharmaceutical education and innovation in China [12][28].

Core Viewpoint - The research conducted by the team led by Cai Yaqi from the Chinese Academy of Sciences establishes a QuEChERS-UPLC-MS/MS method for detecting 20 types of PFAS in human blood, revealing a 100% detection rate for 10 types of PFAS in 15 samples from Shandong Province, with PFOA, PFOS, and 6:2 Cl-PFESA identified as major pollutants [2][3][4]. Summary by Sections Abstract - The study emphasizes the importance of measuring PFAS concentrations in human blood to understand exposure levels and assess health risks. A QuEChERS-UPLC-MS/MS method was developed, utilizing pure acetonitrile for extraction and achieving a total PFAS concentration range of 7.65-51.3 ng·mL⁻¹ in the analyzed samples [4][24]. Experimental Objectives - The objectives include establishing a simple and efficient QuEChERS method for extracting and purifying PFAS from human blood, optimizing UPLC-MS/MS parameters for high sensitivity and accurate quantification, and validating the method's reliability through various metrics [5][6][7]. Experimental Principles - PFAS are hydrophobic and chemically stable, leading to accumulation in blood. The QuEChERS method employs acetonitrile extraction, salt-induced phase separation, and solid-phase extraction to remove matrix interferences, while UPLC-MS/MS provides qualitative and quantitative analysis [8]. Instruments and Reagents - The instruments used include a UPLC system and a triple quadrupole mass spectrometer, along with various auxiliary devices. The target compounds consist of 20 types of PFAS, with isotopically labeled standards and specific solvents and chemicals utilized for the analysis [9][10]. Experimental Methods - Blood samples were collected from 15 volunteers in Shandong, processed using the QuEChERS method, and analyzed using UPLC-MS/MS under optimized conditions [11][12][15]. Method Validation - The method demonstrated a linear range for 20 PFAS from 0.05 to 50 ng·mL⁻¹, with detection limits between 0.010-0.063 ng·mL⁻¹ and quantification limits from 0.032-0.210 ng·mL⁻¹. Recovery rates were satisfactory, meeting quantitative analysis requirements [21][22][23]. Actual Sample Analysis - Analysis of the 15 blood samples showed a total PFAS concentration range of 7.65-51.3 ng·mL⁻¹, with a 100% detection rate for 10 PFAS, highlighting PFOA, PFOS, and 6:2 Cl-PFESA as significant pollutants [23]. Conclusion - The established QuEChERS-UPLC-MS/MS method is efficient and reliable for accurately measuring PFAS in blood, indicating widespread presence of traditional and alternative PFAS in human blood, which raises health risk concerns [24].

Core Viewpoint - Recently, China Medical University announced procurement intentions for 21 items of laboratory equipment, with a total budget of 98.98 million yuan, scheduled for procurement between April and December 2025 [2][3]. Summary by Categories Procurement Overview - The procurement includes advanced equipment such as a holographic non-labeling 3D live cell tomography imaging system, cell energy metabolism analyzer, nanoscale large field three-dimensional combined system, ultracentrifuge, fully automated 3D cell culture instrument, and third-generation gene sequencer [3][4]. Equipment Details - **Fully Automated 3D Cell Culture Instrument**: Integrates automation control, real-time monitoring, and 3D cell culture technology, widely used in tissue engineering, regenerative medicine, drug screening, tumor research, and precision medicine. It simulates in vivo physiological environments better than traditional 2D cell culture [4]. - **Multispectral Super-Resolution Inverted Fluorescence Microscope**: An advanced imaging platform in life sciences, featuring high spatial resolution and multi-channel spectral capabilities, applicable in cell biology, neuroscience, cancer research, developmental biology, and drug development [5]. - **Cell Energy Metabolism Analyzer**: Monitors cell energy metabolism states in real-time, applicable in cancer biology, immunology, stem cell research, drug development, and metabolic diseases. It measures glycolysis and mitochondrial respiration activities [6]. Detailed Procurement List - The procurement list includes various advanced instruments with specific budget allocations, such as: - Holographic 3D live cell imaging system: 17.8 million yuan - Cell energy metabolism analyzer: 26 million yuan - Nanoscale large field three-dimensional combined system: 12 million yuan - Ultracentrifuge: 8.5 million yuan - Fully automated 3D cell culture instrument: 6.5 million yuan - Third-generation gene sequencer: 7.5 million yuan - Multispectral super-resolution inverted fluorescence microscope: 8.5 million yuan [9][10]. Application and Impact - The procurement aims to enhance research capabilities in various fields, including biomedicine, cell biology, and tissue engineering, thereby supporting the development of high-end talent and scientific research at the university [11].

导读： 重点明确支持关键技术研发、支持成果转化、支持企业集聚和发展、支持企业做大做强、支持科学仪器产品拓展应用场景五大支持方向及标准。 特别提示 微信机制调整，点击顶部"仪器信息网" → 右上方"…" → 设为 ★ 星标，否则很可能无法看到我们的推送。 8月21 日，为促进怀柔科学 城科学仪器和传感器产业发展，北京怀柔科学城管理委员会发布《关于精准支持怀柔科学城科学仪器和传感器产 业创新发展的若干措施》（以下简称《若干措施》）。 《若干措施》主要分为适用对象和重点领域、支持内容及标准、申 请流程与监督管理及附则四个章节，旨在 通过18条新政加大对科学仪器与 传感器产业的扶持力度，单个项目最高支持金额达3500万元。 在支持内容及标准方面，特别明确 支持关键技术研发、支持成果转化、支持企业集聚和发展、支持企业做大做强、支持科学仪器产品拓展应用 场景 五大支持方向及标准 。 全文如下： 关于精准支持怀柔科学城科学仪器和传感器产业创新发展的若干措施 为加快落实《深入贯彻落实习近平总书记重要批示精神 加快推动北京国际科技创新中心建设的工作方案》（国科发规〔2023〕41号）《"十 四五"时期北京怀柔综合性国家科学中心 ...

Core Viewpoint - The selection process for the 2025 academicians of the Chinese Academy of Sciences and the Chinese Academy of Engineering has concluded, with a total of 639 valid candidates for the Chinese Academy of Sciences and 660 valid candidates for the Chinese Academy of Engineering [1][2]. Summary by Categories Chinese Academy of Engineering - The Chinese Academy of Engineering confirmed 660 valid candidates for the 2025 academician selection, categorized by various engineering departments [2][4]. - The distribution of candidates across different departments includes: - Mechanical and Transportation Engineering: 68 candidates - Information and Electronic Engineering: 68 candidates - Chemical, Metallurgical, and Materials Engineering: 71 candidates - Energy and Mining Engineering: 72 candidates - Civil, Hydraulic, and Architectural Engineering: 91 candidates - Environmental and Light Textile Engineering: 73 candidates - Agricultural Engineering: 83 candidates - Medical and Health Engineering: 91 candidates - Special Channel: 43 candidates [2][4]. Selection Process - The selection process for the academicians began on April 25, 2025, and the number of new academicians for both the Chinese Academy of Sciences and the Chinese Academy of Engineering is limited to no more than 100 each [2][4].

Core Viewpoint - iNature systematically summarizes the top 20 scholars in the life sciences field employed in Chinese institutions, covering eight subfields including molecular biology, neuroscience, biochemistry, genetics, immunology, medicine, microbiology, and plant science and agriculture [1][2]. Molecular Biology - A total of 6,162 researchers were analyzed in the molecular biology field, with a D-index threshold of 40 for consideration. The acceptance criteria for top researchers are based on D-index, contribution ratio in the specific field, and researchers' awards and achievements [3][4]. - Notable scholars include: - David J. Chen (Chinese University of Hong Kong) - D-index: 105 - Pan Tao (Jinan University) - D-index: 88 - Li Jiayang (Chinese Academy of Sciences) - D-index: 84 [4]. Neuroscience - An analysis was conducted on 30,084 researchers in the neuroscience field, with a D-index threshold of 30 for consideration. The acceptance criteria are similar to those in molecular biology [5][6]. - Notable scholars include: - Pu Muming (Chinese Academy of Sciences) - D-index: 125 - Nikos K. Logothetis (Chinese Academy of Sciences) - D-index: 123 - Helmut Ketternann (Chinese Academy of Sciences) - D-index: 116 [6]. Biochemistry - A total of 88,978 researchers were analyzed in the biochemistry field, with a D-index threshold of 40 for consideration [7]. - Notable scholars include: - Katsuhiko Mikoshiba (Shanghai University of Science and Technology) - D-index: 145 - Deng Chuxia (Macau University) - D-index: 145 - Pak C. Sham (Hong Kong University) - D-index: 132 [7]. Genetics - An analysis was conducted on 6,162 researchers in the genetics field, with a D-index threshold of 40 for consideration [8]. - Notable scholars include: - Zhu Jiankang (Southern University of Science and Technology) - D-index: 173 - Deng Xingwang (Peking University) - D-index: 134 - Yang Huanming (BGI) - D-index: 126 [8][9]. Immunology - A total of 11,980 researchers were analyzed in the immunology field, with a D-index threshold of 40 for consideration [10]. - Notable scholars include: - Guan Yi (Hong Kong University) - D-index: 132 - Gao Fu (Chinese Academy of Sciences) - D-index: 115 - Leo L. M. Poon (Hong Kong University) - D-index: 112 [10]. Medicine - An analysis was conducted on 70,665 researchers in the medicine field, with a D-index threshold of 70 for consideration [11]. - Notable scholars include: - Huang Tianyin (Tsinghua University) - D-index: 202 - Shen Zuyao (Hong Kong University) - D-index: 177 - Joseph Lau (Hong Kong University) - D-index: 163 [11]. Microbiology - A total of 44,555 researchers were analyzed in the microbiology field, with a D-index threshold of 40 for consideration [12]. - Notable scholars include: - Yuan Guoyong (Hong Kong University) - D-index: 164 - Kwok-Hung Chan (Hong Kong University) - D-index: 112 - Xiao Lihua (South China Agricultural University) - D-index: 110 [12][13]. Plant Science and Agriculture - An analysis was conducted on 10,707 researchers in the plant science and agriculture field, with a D-index threshold of 30 for consideration [14]. - Notable scholars include: - Zhu Yongguan (Chinese Academy of Sciences) - D-index: 135 - Zhang Fushuo (China Agricultural University) - D-index: 132 - Zhao Fangjie (Nanjing Agricultural University) - D-index: 126 [14].

Core Insights - The article discusses the anticipated announcement of the 2025 National Natural Science Foundation (NSFC) results, highlighting the uncertainty surrounding the exact timing of the release [3][4][6] - It reviews the funding data over the past four years, noting a significant increase in application volume but a decline in approval rates, particularly after policy changes in 2024 [7][10] Application and Funding Trends - The total number of applications for the NSFC in 2024 reached 384,564, a substantial increase of 80,231 applications or 26.36% compared to 2023, marking a historical high [7] - The total number of funded projects slightly increased to 49,805, which is only a marginal rise of 1,020 projects from 2023, resulting in an overall funding rate drop from 16.06% in 2023 to 13.00% in 2024, a decrease of 3 percentage points [7] Project-Specific Funding Data - For the 2024 NSFC, the approval rates for various project types were as follows: - General projects: 11.66% approval rate with 20,758 out of 177,982 applications funded - Youth projects: 15.54% approval rate with 23,226 out of 149,489 applications funded - Excellent Youth projects: 7.79% approval rate with 654 out of 8,394 applications funded - Distinguished Young Scholars projects: 7.08% approval rate with 433 out of 6,117 applications funded - Key projects: 16.50% approval rate with 745 out of 4,514 applications funded [8][9] Future Outlook - The 2025 NSFC is characterized by a dual nature: a potential drop in approval rates for general projects below 10% and a continued decline in youth fund approvals, contrasted with positive developments such as the opening of new funding channels for innovative groups and a significant increase in budgets for interdisciplinary projects [10]

Core Viewpoint - Nankai University has announced procurement intentions for 49 items of scientific instruments and equipment, with a total budget of 111 million yuan, expected to be purchased between December 2024 and October 2025 [2][3]. Instrument Procurement Summary - The procurement includes various advanced instruments such as Micro Focus X-ray Imaging Systems, Desktop Near-Infrared Systems, Steady/Transient Spectrometers, and Multifunctional Composite Quantum Film Material Preparation Systems [3][4][5][6]. - The total budget for these instruments is 111 million yuan, indicating significant investment in research capabilities [2][3]. Detailed Procurement List - **Micro Focus X-ray Imaging System**: A high-resolution X-ray detection device for non-destructive imaging of materials, with a budget of 1.1 million yuan, expected procurement in December 2024 [9]. - **Desktop Near-Infrared System**: Used for interdisciplinary research in cognitive science and decision-making, with a budget of 5.09 million yuan, expected procurement in December 2024 [9]. - **AI Server for Digital Twin Laboratory**: To enhance teaching effectiveness and research capabilities, with a budget of 5.4 million yuan, expected procurement in December 2024 [9]. - **Behavioral Decision and Cognitive Neuroscience Eye-Tracking System**: For experimental teaching and research, with a budget of 7.91 million yuan, expected procurement in December 2024 [9]. - **Fourier Spectroscopy System**: For molecular structure analysis, with a budget of 1.05 million yuan, expected procurement in December 2024 [13]. - **Quantum Key Distribution Teaching System**: For teaching quantum communication principles, with a budget of 1.06 million yuan, expected procurement in December 2024 [9]. - **Various other instruments**: Including systems for crystal growth, atomic force microscopy upgrades, and phase noise analyzers, with budgets ranging from 118,000 to 320,000 yuan, all expected to be procured by December 2025 [17][18][21][22]. Implications for Research and Development - The procurement of these advanced instruments is expected to significantly enhance the research capabilities of Nankai University, particularly in fields such as quantum technology, cognitive science, and materials science [2][3][9]. - The investment reflects a strategic focus on interdisciplinary research and innovation, aiming to foster high-level academic output and technological advancements [2][3].

Core Viewpoint - Shanghai University has announced procurement intentions for 28 items of scientific instruments and equipment, with a total budget of 95.26 million yuan, expected to be purchased in August 2025 [2][3]. Procurement Summary - The procurement includes advanced instruments such as: - Sub-picometer optical microphone spectral imaging instrument - Mid- and far-infrared spectral high-resolution intelligent testing instrument - Intelligent photon device packaging testing platform - Micro-particle imaging velocimeter [3][4][5]. Detailed Procurement List - **Sub-picometer Optical Microphone Spectral Imaging Instrument**: - Budget: 14 million yuan - Purpose: High-sensitivity acoustic signal detection and spatial distribution analysis [6]. - **Mid- and Far-Infrared Spectral High-Resolution Intelligent Testing Instrument**: - Budget: 150 million yuan - Purpose: High-resolution spectral analysis in the mid-infrared and far-infrared bands [5][8]. - **Intelligent Photon Device Packaging Testing Platform**: - Budget: 110 million yuan - Purpose: High-precision packaging and performance testing of photon devices [8]. - **Micro-particle Imaging Velocimeter**: - Budget: 120 million yuan - Purpose: Velocity field measurement for various flow fields [8]. - **Wafer-Level Physical Vapor Deposition Equipment**: - Budget: 255 million yuan - Purpose: Thin film deposition with specific technical requirements [8]. - **Optical Feature Analyzer**: - Budget: 115 million yuan - Purpose: Performance testing of high-speed optical communication chips [9]. - **MEMS Device Parameter Analyzer**: - Budget: 300 million yuan - Purpose: Measurement of capacitance and current/voltage characteristics [9]. - **Laser Welding Equipment**: - Budget: 155 million yuan - Purpose: High-precision welding for Micro-LED chip manufacturing [11]. - **Automated High-Throughput Alloy Preparation System**: - Budget: 350 million yuan - Purpose: Part of the AI materials design laboratory for alloy preparation and characterization [11]. This procurement initiative reflects the university's commitment to enhancing its research capabilities through advanced scientific instruments and technologies.

Core Viewpoint - Beijing has launched the "National Instrument Beijing Use" plan to promote the evaluation and application of domestic high-end scientific instruments, with a call for proposals for reserve projects from August 19 to September 2, 2025 [1][2]. Policy Updates - The first batch of projects under the "National Instrument Beijing Use" plan aims to enhance the independent innovation capability and competitiveness of high-end scientific instruments in Beijing, with a focus on creating a technology source and industrial cluster for high-end scientific instruments by 2027 [3]. Application Criteria - Eligible applicants include research institutions, universities, healthcare institutions, and technology enterprises registered in Beijing, with a total asset value of scientific instruments not less than 100 million [4]. - Each applicant can submit up to three projects, with each project limited to one product, while each instrument manufacturer can participate with up to three different types of instruments [5]. - The products must be developed and produced by registered instrument companies in Beijing, with specific sales and market conditions outlined for eligibility [6][7]. Support Objectives - The plan includes four main tasks aimed at addressing industry pain points, such as conducting performance evaluations, providing application guidelines, organizing training sessions, and promoting results through media collaboration [8]. - Financial support will be provided upfront upon project approval, with an execution period not exceeding one year [9]. Application Process - The application system is accessible through two online platforms, with the submission window opening on August 19 at 12:00 and closing on September 2 at 17:30 [10].