科创板上市公司独立董事提名人声明与承诺 提名人上海君实生物医药科技股份有限公司董事会，现提名 杨劲为上海君实生物医药科技股份有限公司第四届董事会独立董 事候选人，已充分了解被提名人职业、学历、职称、详细的工作 经历、全部兼职、有无重大失信等不良记录等情况。被提名人已 书面同意出任上海君实生物医药科技股份有限公司第四届董事会 独立董事候选人（参见该独立董事候选人声明）。提名人认为， 被提名人具备独立董事任职资格，与上海君实生物医药科技股份 有限公司之间不存在任何影响其独立性的关系，具体声明并承诺 如下： 一、被提名人具备上市公司运作的基本知识，熟悉相关法律、 行政法规、规章及其他规范性文件，具有五年以上法律、经济、 会计、财务、管理等履行独立董事职责所必需的工作经验。 被提名人已经参加培训并取得证券交易所认可的相关培训证 明材料。 二、被提名人任职资格符合下列法律、行政法规和部门规章 的要求： （一）《中华人民共和国公司法》等关于董事任职资格的规 定； （二）《中华人民共和国公务员法》关于公务员兼任职务的 规定（如适用）； （四）中共中央纪委、中共中央组织部《关于规范中管干部 辞去公职或者退（离）休后担任上市公 ...

召开日期时间：2025 年 9 月 26 日 14 点 40 分 证券代码：688180 证券简称：君实生物 公告编号：临 2025-049 上海君实生物医药科技股份有限公司 关于召开2025年第一次临时股东大会的通知 本公司董事会及全体董事保证公告内容不存在任何虚假记载、误导性陈述或 者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 重要内容提示： 一、 召开会议的基本情况 （一） 股东大会类型和届次 2025年第一次临时股东大会 召开地点：上海市浦东新区平家桥路 100 弄 6 号 7 幢 15 层 （五） 网络投票的系统、起止日期和投票时间。 网络投票系统：上海证券交易所股东大会网络投票系统 网络投票起止时间：自2025 年 9 月 26 日 至2025 年 9 月 26 日 采用上海证券交易所网络投票系统，通过交易系统投票平台的投票时间为股 股东大会召开日期：2025年9月26日 本次股东大会采用的网络投票系统：上海证券交易所股东大会网络投票 系统 （二） 股东大会召集人：董事会 （三） 投票方式：本次股东大会所采用的表决方式是现场投票和网络投票相结 合的方式 （四） 现场会议召开的日 ...

上海君实生物医药科技股份有限公司 2025 年第一次临时股东大会会议资料 2025 年 9 月 | 年第一次临时股东大会会议须知 1 | 2025 | | --- | --- | | 年第一次临时股东大会会议议程 3 | 2025 | | 年第一次临时股东大会会议议案 5 | 2025 | | 议案一 | 5 | | 《关于选举独立非执行董事的议案》 5 | | | 议案二 | 6 | | 《关于修订部分内部管理制度的议案》 6 | | | 议案三 | 53 | | 《关于变更注册资本、取消监事会、修订<公司章程>及其附件的议案》 53 | | | 议案四 | 55 | | 东授予 股股票期权的议案》 A | 55 | | 议案五 | 56 | | 《关于<公司 年 2025 A | 股股票期权激励计划实施考核管理办法>的议案》 56 | | 议案六 | 57 | | 57 | | | 议案七 | 59 | | 年 《关于<公司 2025 H 股股票期权激励计划>的议案》 | 59 | | 议案八 | 60 | | 关事宜的议案》 60 | | 上海君实生物医药科技股份有限公司 2025 年第一次临时股东大会 ...

Core Viewpoint - Junshi Biosciences (01877) experienced a significant stock increase of over 10%, attributed to the approval of clinical trial application for JT118, a dual-target recombinant protein vaccine aimed at preventing monkeypox virus infection [1] Group 1: Clinical Trial Approval - Junshi Biosciences' subsidiary, Shanghai Juntuo Biopharmaceutical Technology Co., Ltd., received the Drug Clinical Trial Approval Notification from the National Medical Products Administration for JT118 [1] - JT118 is a recombinant protein vaccine composed of monkeypox virus antigens A35 and M1, demonstrating significant protective effects in preclinical studies against both vaccinia virus and monkeypox virus in large animal models, with good safety profiles [1] Group 2: Research Recognition - Multiple research outcomes from Junshi Biosciences, including the anti-BTLA monoclonal antibody tifcemalimab and the anti-PD-1 monoclonal antibody treprilumab, have been selected for oral presentations and posters at the 2025 World Lung Cancer Conference (WCLC) scheduled for September 6-9, 2025, in Barcelona, Spain [1]

Group 1 - Junshi Bioscience (01877) shares rose over 10%, currently up 11.03% at HKD 34.22, with a trading volume of HKD 516 million [1] - The company announced that its subsidiary, Shanghai Juntao Biopharmaceutical Technology Co., Ltd., received approval from the National Medical Products Administration for the clinical trial of JT118 injection, a "dual" recombinant protein vaccine aimed at preventing monkeypox virus infection [1] - Preclinical studies indicate that JT118 shows significant protective effects against vaccinia virus/monkeypox virus infections in small animal models, with good safety profiles [1] Group 2 - The 2025 World Lung Cancer Conference (WCLC) will be held from September 6 to 9, 2025, in Barcelona, Spain [1] - Junshi Bioscience's innovative products, including anti-BTLA monoclonal antibody tifcemalimab and anti-PD-1 monoclonal antibody teriprizumab, have multiple research results selected for oral presentations and posters at the conference, showcasing the latest advancements in lung cancer research [1]

Company Overview - Junshi Biosciences has seen a stock price increase of 73.44% year-to-date, with a 7.80% rise in the last five trading days, an 18.95% increase over the last 20 days, and a 22.64% increase over the last 60 days [2] - The company specializes in the research and industrialization of monoclonal antibody drugs and other therapeutic protein drugs, as well as providing technical services and technology transfer related to monoclonal antibody drug development [2] Financial Performance - For the period from January to June 2025, Junshi Biosciences reported revenue of 1.168 billion yuan, representing a year-on-year growth of 48.64%, while the net profit attributable to shareholders was -413 million yuan, showing a year-on-year increase of 36.01% [2] Shareholder Information - As of June 30, 2025, the number of shareholders for Junshi Biosciences was 31,200, an increase of 5.88% from the previous period, with an average of 24,543 circulating shares per shareholder, a decrease of 5.56% [2] - The top ten circulating shareholders include notable ETFs, with 华夏上证科创板50成份ETF holding 29.7167 million shares (a decrease of 536,700 shares), and 易方达上证科创板50ETF holding 22.2132 million shares (an increase of 630,000 shares) [3]

Core Viewpoint - The article discusses the upcoming 2025 Shanghai Leading Industries and the 14th Pharmaceutical CEO Forum, highlighting the focus on innovation and global expansion of Chinese pharmaceutical companies [1]. Summary by Sections Event Overview - The event will take place on September 4-5, 2025, at the Mandarin Oriental Hotel in Pudong, Shanghai, featuring nearly a hundred executives from listed companies, including chairpersons, CEOs, and industry leaders [4]. Morning Sessions - The morning session on September 4 will include a keynote speech and several roundtable discussions focusing on topics such as the global expansion of Chinese pharmaceutical companies and the search for the next billion-dollar drug [4][5]. - Notable discussions will include: - "From Local Innovation to Global Leadership: The Era of Chinese Pharmaceutical Companies Going Abroad" [4]. - "The Birth of Big Drugs is the Future of Pharmaceuticals: Finding the Next Billion-Dollar Bomb" [4]. Afternoon Sessions - The afternoon will feature discussions on future disease areas and technologies worth exploring for pharmaceutical assets going abroad, as well as the new cycle of Chinese innovative drugs under global competition [5][6]. - Additional topics will cover advancements in drug development platforms and the emerging field of brain-machine interfaces [6]. TMT Forum - The TMT (Technology, Media, and Telecommunications) forum will also take place, discussing AI's impact on various industries, including gaming and healthcare [7][8]. - Key topics will include AI innovations in mobile internet ecosystems and the future of AI in healthcare [7]. Pharmaceutical Sub-Forum - The pharmaceutical sub-forum will address topics such as ADC technology exploration, probiotic delivery systems, and the future development paths of dual antibodies and XDC [8]. - Discussions will also focus on the integration of medical insurance and the innovative practices in building a multi-level medical security system in China [8].

Core Viewpoint - Junshi Bioscience has shown significant stock price appreciation in 2023, with a year-to-date increase of 73.14% and notable gains over various trading periods [2]. Group 1: Stock Performance - As of September 3, Junshi Bioscience's stock price reached 47.32 CNY per share, with a market capitalization of 48.583 billion CNY [1]. - The stock has increased by 9.08% over the last 5 trading days, 14.63% over the last 20 days, and 29.22% over the last 60 days [2]. Group 2: Financial Performance - For the first half of 2025, Junshi Bioscience reported revenue of 1.168 billion CNY, representing a year-on-year growth of 48.64% [2]. - The company recorded a net profit attributable to shareholders of -413 million CNY, which is a 36.01% increase compared to the previous period [2]. Group 3: Shareholder Information - As of June 30, 2025, the number of shareholders for Junshi Bioscience increased to 31,200, up by 5.88% from the previous period [2]. - The average number of circulating shares per shareholder decreased by 5.56% to 24,543 shares [2]. Group 4: Institutional Holdings - As of June 30, 2025, the top ten circulating shareholders include Huaxia SSE STAR 50 ETF, which holds 29.7167 million shares, a decrease of 536,700 shares from the previous period [3]. - E Fund SSE STAR 50 ETF increased its holdings to 22.2132 million shares, an increase of 630,000 shares [3].

FF301 股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2025年8月31日 狀態: 新提交 致：香港交易及結算所有限公司 公司名稱: 上海君實生物醫藥科技股份有限公司 呈交日期: 2025年9月3日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | H | | | 於香港聯交所上市 (註1) | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 01877 | 說明 | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | 法定/註冊股本 | | | 上月底結存 | | | 260,295,700 | RMB | | 1 RMB | | 260,295,700 | | 增加 / 減少 (-) | | | 0 | | | RMB | | 0 | | 本月底結存 | | | 260,295,700 | RMB | | 1 RMB | | 260,295,700 | | 2. 股份分類 | 普通股 | 股份類別 ...

FF301 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | H | | | 於香港聯交所上市 (註1) | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 01877 | 說明 | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | 法定/註冊股本 | | | 上月底結存 | | | 260,295,700 | RMB | | 1 RMB | | 260,295,700 | | 增加 / 減少 (-) | | | 0 | | | RMB | | 0 | | 本月底結存 | | | 260,295,700 | RMB | | 1 RMB | | 260,295,700 | | 2. 股份分類 | 普通股 | 股份類別 | A | | 於香港聯交所上市 (註1) | 否 | | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 688180 | 說明 | | ...