该项目不仅为君实生物自身提供了高效合规的解决方案，也为生物医药行业数字化转型提供了可复制、 可推广的实施路径。未来，君实生物将持续深化数字化、智能化转型，以技术创新驱动生产效率与产品 质量双提升，为全球患者提供更安全、更可及的创新药物，助力生物医药产业高质量发展。 2025年，君实生物在上海临港生产基地开展的"商业化产线电子批记录(EBR)系统搭建"项目，开创了生 物制药行业在商业化生产中全面应用EBR的先例。传统纸质批记录依赖人工操作，存在数据易偏差、流 程效率低等痛点。为此，君实生物构建了一套覆盖制剂生产全流程的多系统集成数字化管控体系。该系 统以MES/EBR为核心，严格遵循ISA-95标准分层设计，深度融合DCS、WMS、EMS等系统，实现从原 液处理到成品入库的全链路标准化与透明化管理。项目通过"所见即所得"的电子工作指引，将复杂工艺 分解为1780个标准化操作步骤，并设置4380项异常监控点，形成数字化工作流。其核心亮点包括：全链 路数据自动采集，消除人工录入误差；合规性自动核实与实时预警，替代传统人工核对；以及"异常驱 动的审核模式"，大幅提升批记录审核与放行效率。项目落地后，在合规、效率与供应 ...

（文章来源：每日经济新闻） 每经AI快讯，天眼查工商信息显示，近日，上海君亦乐生物科技有限公司成立，注册资本5亿元人民 币，经营范围包括货物进出口、技术进出口、信息咨询服务等。股东信息显示，该公司由君实生物全资 持股。 ...

Core Viewpoint - Shanghai Junyile Biotechnology Co., Ltd. has been established with a registered capital of 500 million RMB, fully owned by Shanghai Junshi Biosciences Co., Ltd. [1] Company Information - The legal representative of Shanghai Junyile Biotechnology Co., Ltd. is Xie Wan [1] - The company is registered with a capital of 500 million RMB [1] - The business scope includes technology services, development, consulting, exchange, transfer, promotion, import and export of goods, and information consulting services [1] - The company is classified under the national standard industry of scientific research and technical service industry, specifically technology promotion and application service industry [1] - The registered address is located in the China (Shanghai) Pilot Free Trade Zone Lingang New Area [1] - The company is a limited liability company with no fixed term of operation [1] Shareholding Structure - Shanghai Junshi Biosciences Co., Ltd. holds 100% of the shares in Shanghai Junyile Biotechnology Co., Ltd. [1]

Core Viewpoint - Junshi Biosciences (688180.SH) is currently experiencing a decline in stock price, closing at 35.29 yuan with a drop of 3.42%, indicating a state of being below its initial public offering (IPO) price [1] Fundraising and Financial Performance - Junshi Biosciences raised a total of 4.836 billion yuan from its IPO on July 15, 2020, with a net amount of 4.497 billion yuan after deducting issuance costs, exceeding the original plan by 1.797 billion yuan [1] - The company planned to raise 2.7 billion yuan for innovative drug research, industrialization projects, bank loan repayment, and working capital [1] - The company raised an additional 3.7765 billion yuan through a private placement of 70 million shares at 53.95 yuan per share in 2022, with a net amount of approximately 3.7448 billion yuan after costs [2] - The total funds raised by Junshi Biosciences from both public and private placements amount to 8.612 billion yuan [3] Profitability and Revenue Trends - From 2016 to 2024, Junshi Biosciences reported negative net profits, with figures ranging from -1.35 billion yuan to -23.88 billion yuan [3] - For the first three quarters of 2025, the company achieved a revenue of 1.806 billion yuan, reflecting a year-on-year growth of 42.06%, while the net profit attributable to shareholders was -596 million yuan, an improvement from -927 million yuan in the previous year [3] - The net cash flow from operating activities for the same period was -343 million yuan, compared to -1.113 billion yuan in the previous year [3]

Core Viewpoint - Junshi Biosciences has experienced fluctuations in stock price and trading volume, with a recent decline in share price despite a year-to-date increase. The company is involved in the research and commercialization of monoclonal antibody drugs and other therapeutic proteins, with a significant portion of its revenue coming from drug sales [1][2]. Group 1: Stock Performance - On January 16, Junshi Biosciences' stock fell by 2.00%, trading at 36.72 CNY per share, with a total market capitalization of 37.7 billion CNY [1]. - The stock has increased by 7.49% year-to-date but has seen a decline of 6.33% over the last five trading days [1]. - The trading volume was 1.76 billion CNY, with a turnover rate of 0.62% [1]. Group 2: Financial Performance - For the period from January to September 2025, Junshi Biosciences reported a revenue of 1.806 billion CNY, representing a year-on-year growth of 42.06% [2]. - The company recorded a net profit attributable to shareholders of -596 million CNY, which is a 35.72% increase compared to the previous period [2]. Group 3: Shareholder Information - As of September 30, 2025, the number of shareholders for Junshi Biosciences increased to 35,900, a rise of 15.17% from the previous period [2]. - The average number of circulating shares per shareholder decreased by 12.96% to 21,361 shares [2]. Group 4: Company Overview - Junshi Biosciences, established on December 27, 2012, and listed on July 15, 2020, is based in Shanghai and focuses on the development and commercialization of monoclonal antibody drugs and other therapeutic proteins [1]. - The company's main revenue sources include drug sales (90.67%), technology licensing and royalties (8.74%), and technical services (0.59%) [1].

Core Viewpoint - Junshi Biosciences' stock price has shown fluctuations, with a recent decline of 2.06% and a year-to-date increase of 10.16%, indicating volatility in market performance [1][2]. Group 1: Stock Performance - As of January 15, Junshi Biosciences' stock price is reported at 37.63 CNY per share, with a total market capitalization of 38.634 billion CNY [1]. - The stock has experienced a 0.08% decline over the last five trading days, a 5.17% increase over the last 20 days, and a 3.49% decline over the last 60 days [2]. Group 2: Financial Performance - For the period from January to September 2025, Junshi Biosciences achieved a revenue of 1.806 billion CNY, representing a year-on-year growth of 42.06% [2]. - The company reported a net profit attributable to shareholders of -596 million CNY, which is a year-on-year increase of 35.72% [2]. Group 3: Shareholder Information - As of September 30, 2025, the number of shareholders for Junshi Biosciences increased by 15.17% to 35,900, while the average circulating shares per person decreased by 12.96% to 21,361 shares [2]. - The top ten circulating shareholders include notable ETFs, with E Fund's SSE STAR 50 ETF holding 19.3929 million shares, a decrease of 2.8203 million shares from the previous period [3].

Group 1 - The core viewpoint of the news is that Junshi Biosciences experienced a decline in stock price and significant trading activity, indicating potential investor concerns and market volatility [1] - On January 14, Junshi Biosciences' stock fell by 2.36%, with a trading volume of 678 million yuan, and a net financing outflow of 24.32 million yuan [1] - As of January 14, the total margin balance for Junshi Biosciences was 1.341 billion yuan, with a financing balance of 1.325 billion yuan, representing 4.50% of the circulating market value, which is above the 60th percentile of the past year [1] Group 2 - Junshi Biosciences, established on December 27, 2012, focuses on the research and commercialization of monoclonal antibody drugs, with 90.67% of its revenue coming from drug sales [2] - For the period from January to September 2025, Junshi Biosciences reported revenue of 1.806 billion yuan, a year-on-year increase of 42.06%, while the net profit attributable to shareholders was -596 million yuan, reflecting a 35.72% increase [2] - As of September 30, 2025, the number of shareholders increased by 15.17% to 35,900, while the average circulating shares per person decreased by 12.96% to 21,361 shares [2]

Core Viewpoint - Junshi Biosciences' stock price has shown fluctuations, with a recent decline of 2.11%, while the company has experienced a year-to-date increase of 12.76% in stock value [1][2]. Group 1: Stock Performance - As of January 14, Junshi Biosciences' stock price is reported at 38.52 CNY per share, with a trading volume of 4.05 billion CNY and a market capitalization of 39.548 billion CNY [1]. - The stock has increased by 12.76% year-to-date, with a 1.90% rise over the last five trading days and a 5.30% increase over the last 20 days, while it has slightly decreased by 0.39% over the last 60 days [2]. Group 2: Financial Performance - For the period from January to September 2025, Junshi Biosciences achieved a revenue of 1.806 billion CNY, representing a year-on-year growth of 42.06%. However, the net profit attributable to shareholders was -596 million CNY, reflecting a year-on-year increase of 35.72% in losses [2]. Group 3: Shareholder Information - As of September 30, 2025, the number of shareholders for Junshi Biosciences is 35,900, which is an increase of 15.17% compared to the previous period. The average number of circulating shares per shareholder is 21,361, a decrease of 12.96% [2]. - Among the top ten circulating shareholders, E Fund's SSE STAR 50 ETF holds 19.3929 million shares, a decrease of 2.8203 million shares from the previous period, while Huaxia's SSE STAR 50 ETF holds 18.9720 million shares, down by 1.0745 million shares [3].

Group 1 - The core viewpoint of the news highlights the trading performance and financial metrics of Junshi Biosciences, indicating a significant level of financing activity and a high balance in margin trading [1][2] - On January 13, Junshi Biosciences saw a stock price increase of 1.71% with a trading volume of 635 million yuan, and the net financing purchase was 4.0162 million yuan [1] - As of January 13, the total margin trading balance for Junshi Biosciences reached 1.365 billion yuan, with a financing balance of 1.349 billion yuan, accounting for 4.47% of the circulating market value [1] Group 2 - Junshi Biosciences, established on December 27, 2012, focuses on the research and commercialization of monoclonal antibody drugs and other therapeutic protein drugs, with 90.67% of its revenue coming from drug sales [2] - For the period from January to September 2025, Junshi Biosciences reported a revenue of 1.806 billion yuan, reflecting a year-on-year growth of 42.06%, while the net profit attributable to shareholders was -596 million yuan, a 35.72% increase year-on-year [2] - As of September 30, 2025, the number of shareholders for Junshi Biosciences increased by 15.17% to 35,900, while the average circulating shares per person decreased by 12.96% to 21,361 shares [2]

Group 1 - The core viewpoint of the news is that Junshi Biosciences experienced a decline in stock price while showing significant activity in financing and margin trading, indicating a high level of investor interest and potential volatility in the stock [1][2] Group 2 - On January 12, Junshi Biosciences' stock fell by 1.30%, with a trading volume of 5.09 billion yuan. The financing buy-in amount for the day was 60.41 million yuan, while the financing repayment was 44.22 million yuan, resulting in a net financing buy of 16.19 million yuan [1] - As of January 12, the total margin trading balance for Junshi Biosciences was 1.36 billion yuan, with the financing balance accounting for 4.54% of the circulating market value, which is above the 70th percentile level over the past year [1] - In terms of securities lending, on January 12, Junshi Biosciences had 6171 shares repaid and 800 shares sold short, with a short selling amount of 31,000 yuan. The remaining short selling volume was 388,300 shares, with a short selling balance of 15.02 million yuan, exceeding the 90th percentile level over the past year [1] Group 3 - Junshi Biosciences, established on December 27, 2012, focuses on the research and commercialization of monoclonal antibody drugs and other therapeutic protein drugs, with 90.67% of its revenue coming from drug sales [2] - As of September 30, the number of shareholders for Junshi Biosciences was 35,900, an increase of 15.17% from the previous period, while the average circulating shares per person decreased by 12.96% [2] - For the period from January to September 2025, Junshi Biosciences reported a revenue of 1.806 billion yuan, a year-on-year increase of 42.06%, while the net profit attributable to shareholders was -596 million yuan, a year-on-year increase of 35.72% [2] - As of September 30, 2025, the top ten circulating shareholders included E Fund's SSE STAR 50 ETF and Huaxia's SSE STAR 50 Component ETF, with both funds reducing their holdings compared to the previous period [2]