FF305 翌日披露報表 (股份發行人 ── 已發行股份或庫存股份變動、股份購回及/或在場内出售庫存股份) 表格類別： 股票 狀態： 新提交 公司名稱： 無錫藥明康德新藥開發股份有限公司 呈交日期： 2025年8月5日 如上市發行人的已發行股份或庫存股份出現變動而須根據《香港聯合交易所有限公司（「香港聯交所」）證券上市規則》(「《主板上市規則》」)第13.25A條 / 《香港聯合交易所有限公司GEM證券 上市規則》(「《GEM上市規則》」)第17.27A條作出披露，必須填妥第一章節 。 FF305 | 7). | 購回股份(或其他證券)但沒有註銷 | 282,748 | 0.01 % | RMB | 70.77 | | --- | --- | --- | --- | --- | --- | | | 茲提述本公司於2025年3月17日刊發的公告，於2025年3月26日刊發的 | | | | | | | 通函，及於2025年4月29日刊發的投票結果公告。 | | | | | | | 於2025年7月4日，本公司實施2025年第一次回購，并回購282,748股A | | | | | | | 股股份。 | | | | ...

Summary of WuXi XDC Cayman Inc. Conference Call Company Overview - **Company**: WuXi XDC Cayman Inc. - **Industry**: China Healthcare, specifically within the Contract Development and Manufacturing Organization (CDMO) sector - **Ticker**: 2268.HK Key Points Earnings and Growth - WuXi XDC has the highest earnings visibility within its CDMO coverage, with management guiding for over 30% earnings CAGR from 2024 to 2028 [3] - Preliminary earnings growth for 1H25 was over 60% YoY, attributed to strong demand, market share gains, and capacity scale-up [3] - The company reported "high/full" capacity utilization on its first two drug product lines (DP1 and DP2), indicating robust operational efficiency [3] Capacity Expansion - The newly GMP certified DP3 line in Wuxi city has an annual capacity of 7 million vials, doubling the total DP capacity to 15 million vials [8] - The DP3 line supports both clinical and commercial scale manufacturing, with high-speed filling capabilities of 300 vials per minute [8] - An upcoming facility in Singapore's Tuas Biomedical Park is projected to add another 8 million vials of capacity, enhancing the company's dual-sourcing strategy [3][8] Market Trends - The CDMO sector is experiencing an up-cycle, with a re-acceleration of investments noted in late 2024 and early 2025 following a post-COVID pullback [4] - Global leaders in the CDMO space, including WuXi group companies, have reported consensus beats and/or raised guidance for the year, with the US market being a significant driver of outperformance [4] Financial Metrics - Current market cap is approximately RMB 63,366.3 million, with an enterprise value of RMB 60,158.2 million [6] - Revenue projections for the next few years are as follows: - 2024: RMB 4,052 million - 2025: RMB 5,542 million - 2026: RMB 7,401 million - 2027: RMB 9,659 million [6] - EPS estimates are projected to grow from RMB 0.91 in 2024 to RMB 2.17 in 2027 [6] Risks and Opportunities - **Upside Risks**: - Increasing orders from all stages of drug development - Successful launch of blockbuster products - Accelerated gross margin improvement from the new Singapore facility [11] - **Downside Risks**: - Potential deceleration in biotech funding and pipeline progression - Late-stage and commercial contracts missing sales expectations - Lower-than-expected gross margin improvement from new facilities [11] Valuation - The price target for WuXi XDC is set at HK$60.00, indicating a 4% upside from the current price of HK$57.55 [6] Conclusion WuXi XDC Cayman Inc. is positioned for significant growth within the CDMO sector, supported by strong earnings visibility, capacity expansion, and favorable market trends. However, potential risks related to market dynamics and operational performance should be monitored closely.

Group 1 - Bank of America has raised the long-term revenue forecast for WuXi AppTec (603259) with a compound annual growth rate (CAGR) of earnings per share adjusted to 16.2% from 2025 to 2032 [1] - The target price for WuXi AppTec's Hong Kong shares has been increased from HKD 115.7 to HKD 123, and the A-share target price has been raised from RMB 107.6 to RMB 114.4, maintaining a "Buy" rating due to robust order growth and operational efficiency improvements [1] - The total value of licensing transactions in China's biotechnology and pharmaceutical industry surged by 135% year-on-year to USD 60 billion in the first half of the year [1] Group 2 - Bank of America has also raised long-term revenue forecasts for Zai Lab (603127) and Fonda Holdings (01521) due to improved demand outlook [2] - The firm expects industry leader WuXi AppTec to continue gaining market share due to its integrated platform and strong operational efficiency, preferring it over Zai Lab and Fonda Holdings, which are rated "Underperform" [2] - The target price for Zai Lab's Hong Kong shares has been increased from HKD 9.3 to HKD 11, and the A-share target price has been raised from RMB 8.5 to RMB 10.1, while Fonda Holdings' target price has been adjusted from HKD 0.8 to HKD 0.95 [2]

Group 1 - Bank of America Securities raised the long-term revenue forecast for WuXi AppTec (02359, 603259.SH), adjusting the compound annual growth rate of earnings per share from 2025 to 2032 to 16.2% [1] - The target price for WuXi AppTec's Hong Kong stock was increased from HKD 115.7 to HKD 123, and the A-share target price was raised from RMB 107.6 to RMB 114.4, maintaining a "Buy" rating due to robust order growth and improved operational efficiency [1] - In the first half of the year, the total value of licensing transactions in China's biotechnology and pharmaceutical industry surged by 135% year-on-year to USD 60 billion, indicating a strong market trend [1] Group 2 - Bank of America also raised long-term revenue forecasts for Zai Lab (06127, 603127.SH) and Fonda Holdings (01521) due to improved demand outlook [2] - However, the industry leader WuXi AppTec is expected to continue gaining market share due to its integrated platform and strong operational efficiency, leading to a preference for WuXi AppTec over Zai Lab and Fonda Holdings, which maintain an "Underperform" rating [2] - The target price for Zai Lab's Hong Kong stock was increased from HKD 9.3 to HKD 11, and the A-share target price was raised from RMB 8.5 to RMB 10.1, while Fonda Holdings' target price was adjusted from HKD 0.8 to HKD 0.95 [2]

中邮证券研报指出，药明康德盈利能力稳步提升，上调全年业绩指引。上半年归母净利润85.6亿元 （+101.9%），25Q2归母净利润48.9亿元（+112.8%），整体业绩符合此前业绩预告。截止2025年6月底 公司持续经营业务在手订单达到566.9亿元（+37.2%），相较一季报公布3月底47.1%的增速有所放缓， 预计与公司产能利用率处于高位有关。药明康德为全球领先的"一体化、端到端"的新药研发服务平台， 考虑公司核心Chemistry业务有望恢复较快增速、盈利能力也将稳步提升，目前PE处于2018年5月以来相 对低位水平，首次覆盖，给予"买入"评级。 ...

Group 1 - The core viewpoint is that the liquidity and fundamentals of the Chinese healthcare industry continue to improve, maintaining a positive outlook for the healthcare sector [1] - The report indicates that the weak U.S. employment data may lead to heightened expectations for monetary easing in the second half of the year, suggesting an improved outlook for the industry [1] - The report highlights that the industry fundamentals are recovering, with a month-on-month increase in hospital prescription volumes in July, and significant profit growth expected in the third quarter due to the release of more innovative drugs [1] Group 2 - The company prefers leading large pharmaceutical firms and suggests avoiding companies overly reliant on biosimilars in the short term [2] - Selected stocks include: CSPC Pharmaceutical Group (01093), Sinopharm Group (01099), Hansoh Pharmaceutical (03692), and others [2] - The report emphasizes that the uncertainty in U.S. Treasury yields may prompt a reallocation of funds, further improving the liquidity of innovative drug assets [1]

里昂指出，行业基本面持续复苏，7月院内处方量环比提升，随着更多创新药放量，第三季行业盈利有 望实现显著增长，加上美债不确定性可能促使资金重新配置，进一步改善创新药资产流动性，相信行业 拐点已过，未来将迎来盈喜等正面催化剂。 该行偏好领先大型药厂，短期而言避开过度依赖生物仿制药的公司。该行选股包括石药集团(01093)、 新诺威(300765.SZ)、翰森制药(03692)、爱尔眼科(300015.SZ)、恒瑞医药(01276,600276.SH)、康方生物 (09926)、中生制药(01177)、国药控股(01099)、康哲药业(00867)、大参林(603233.SH)、华东医药 (000963.SZ)、泰格医药(03347)及药明康德(02359)。 智通财经APP获悉，里昂发布研报称，中国医疗健康行业流动性及基本面持续改善，维持对医疗健康板 块正面看法，指出美国就业数据疲软或市场对下半年货币宽松预期急升温，预示着行业下半年改善前 景，相信特朗普再提最惠国药品定价政策及安徽启动生物类似药集中采购，对行业影响则相对有限。 ...

中邮证券研报指出，药明康德盈利能力稳步提升，上调全年业绩指引。上半年归母净利润85.6亿元 （+101.9%），25Q2归母净利润48.9亿元（+112.8%），整体业绩符合此前业绩预告。截止2025年6月底 公司持续经营业务在手订单达到566.9亿元（+37.2%），相较一季报公布3月底47.1%的增速有所放缓， 预计与公司产能利用率处于高位有关。药明康德为全球领先的"一体化、端到端"的新药研发服务平台， 考虑公司核心Chemistry业务有望恢复较快增速、盈利能力也将稳步提升，目前PE处于2018年5月以来相 对低位水平，首次覆盖，给予"买入"评级。 ...

Core Viewpoint - The A-share market is experiencing a phase of intensive disclosure of semi-annual reports, with companies that exceed expectations receiving significant attention from the market, indicating a positive influx of capital despite a complex economic environment [1] Group 1: Performance Highlights - A total of 59 stocks have been recognized by brokerage institutions for exceeding performance expectations, including major companies such as CATL, Industrial Fulian, Zijin Mining, Muyuan Foods, and WuXi AppTec [3] - The electric equipment industry stands out with 8 stocks making the list of exceeding expectations, reflecting a high overall industry prosperity [4] - 18 stocks reported a net profit growth of over 100% in the first half of the year, with Zhimin Da achieving a remarkable net profit growth of 21.48 times, driven by significant order growth in embedded modules and strong performance in missile and AI products [4] Group 2: Market Trends - The 59 stocks that exceeded expectations have seen an average increase of 37.45% year-to-date, significantly outperforming the Shanghai Composite Index [5] - Six stocks have doubled in value, including Shijia Photon, Jieput, Xinyi Sheng, Zhenyu Technology, Zhimin Da, and Craft Home [5] - Financing funds have shown strong interest in stocks with exceeding performance, with 18 such stocks seeing a net buy-in of over 100 million yuan since July, led by Xinyi Sheng with a net buy-in of 3.406 billion yuan [5] Group 3: Industry Leaders - Industry leaders such as WuXi AppTec, CATL, Zijin Mining, and Zhongji Xuchuang have also seen significant increases in financing, reinforcing their investment value due to their technological advantages and market positions [5] - Suotong Development is expected to report a net profit of 450 million to 540 million yuan in the first half of 2025, representing a year-on-year growth of 13.35 to 16.22 times, benefiting from rising pre-baked anode prices and strong market demand [5]

Group 1 - The core viewpoint of the article highlights that 59 stocks have reported "better than expected" performance according to brokerage institutions, including major companies with market capitalizations exceeding 100 billion [1] - Notable companies that reported exceeding expectations include CATL, Industrial Fulian, Zijin Mining, Muyuan Foods, Zhongji Xuchuang, and WuXi AppTec [1] - Following the announcement of these better-than-expected performance data, several stocks have seen significant increases in net purchases from financing clients, with 18 stocks having net purchases exceeding 100 million since July [1]