Core Points - The announcement details the release of part of the pledged shares by shareholder Gu Meifang, who currently holds 10,322,035 shares, representing 1.38% of the total share capital of the company [1] - After the release of the pledge, Gu Meifang has a total of 5,000,000 pledged shares, which accounts for 48.44% of her holdings [1] - The company previously announced a cash dividend of 0.40 yuan per share (before tax) and a capital reserve increase of 0.4 shares per share on July 19, 2023 [1] Summary of Key Information - As of the announcement date, Gu Meifang's pledged shares increased from 1,000,000 to 1,400,000 shares following the capital increase [1] - The notice of the release of pledged shares was received on November 17, 2025, and the company is providing specific details in this announcement [1]

Core Viewpoint - The company announced that shareholder Gu Meifang has released the pledge on 1.4 million shares, reducing the total pledged shares to 5 million, which is 48.44% of her holdings [1] Summary by Relevant Sections - **Shareholder Actions** - Gu Meifang has released the pledge on 1.4 million shares as of November 17, 2025 [1] - After the release, Gu Meifang holds a total of 10.322 million shares, representing 1.38% of the company's total share capital [1] - **Pledged Shares** - Following the release of the pledge, the total number of pledged shares held by Gu Meifang is now 5 million [1] - This represents 48.44% of her total shareholding [1]

Group 1 - The core point of the article is that Zhaoyan New Drug (SH 603127) announced the release of share pledges by Gu Meifang, who holds approximately 10.32 million shares, accounting for 1.38% of the company's total share capital [1] - After the release of the pledge, Gu Meifang has a total of 5 million shares pledged, which represents 48.44% of her holdings [1] - For the year 2024, Zhaoyan New Drug's revenue composition is projected to be 95.0% from preclinical research services, 4.95% from clinical services, and 0.04% from sales of laboratory animals and related products [1] Group 2 - As of the announcement, Zhaoyan New Drug has a market capitalization of 23.8 billion yuan [1]

本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或者重大 遗漏，并对其内容的真实性、准确性和完整性承担个别及连带责任。 重要内容提示: 证券代码：603127 证券简称：昭衍新药 公告编号：2025-048 北京昭衍新药研究中心股份有限公司 关于股东部分股份解除质押的公告 2025 年 11 月 18 日 2025 年 11 月 17 日，公司接到股东顾美芳女士将其持有公司部分质押股份解除质押的 通知，现将具体情况公告如下： | 股东名称 | | | 顾美芳 | | --- | --- | --- | --- | | 本次解质股份 | | | 1,400,000 | | 占其所持股份比例 | | | 13.56% | | 占公司总股本比例 | | | 0.19% | | 解质时间 | 2025 年 | 11 月 | 14 日 | | 持股数量 | | | 10,322,035 | | 持股比例 | | | 1.38% | | 剩余被质押股份数量 | | | 5,000,000 | | 剩余被质押股份数量占其所持股份比例 | | | 48.44% | | 剩余被质押股份数量占公司总股本比例 | ...

Core Viewpoint - Zhaoyan New Drug (06127) announced the release of 1.4 million shares from pledge by shareholder Gu Meifang, reducing her pledged shares to 5 million, which is 48.44% of her total holdings [1] Summary by Relevant Sections - **Shareholder Actions** - Gu Meifang has released 1.4 million shares from pledge [1] - After the release, Gu Meifang holds a total of 10.322 million shares, representing 1.38% of the company's total share capital [1] - **Pledged Shares** - The total number of pledged shares held by Gu Meifang is now 5 million [1] - This represents 48.44% of her total shareholding [1]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不 負 責，對 其 準 確 性 或 完 整 性 亦 不 發 表 任 何 聲 明，並 明 確 表 示，概 不 對 因 本 公 告 全部或任何部分內容而產生或因倚賴該等內容而引致的任何損失承擔任何責 任。 JOINN LABORATORIES (CHINA) CO., LTD. 北京昭衍新藥研究中心股份有限公司 （於 中 華 人 民 共 和 國 註 冊 成 立 的 股 份 有 限 公 司） （股 份 代 號：6127） 董事長 中 國 北 京，2025年11月17日 於 本 公 告 日 期，董 事 會 包 括 主 席 兼 執 行 董 事 馮 宇 霞 女 士、執 行 董 事 高 大 鵬 先 生、孫雲霞女士、羅樨女士及顧靜良先生，及獨立非執行董事張帆先生、楊福全 先 生、陽 昌 雲 先 生 及 應 放 天 先 生。 证券代码：603127 证券简称：昭衍新药 公告编号：2025-048 北京昭衍新药研究中心股份有限公司 海外監管公告 本公告乃北京昭衍新藥研究中心股份有限公司（「本公司」）根據香港聯合交易 所有限公司證券上市規則第13.10B條 而 作 出 ...

南财智讯11月17日电，昭衍新药公告，2025年11月17日，公司接到股东顾美芳女士通知，其于2025年11 月14日将其持有公司的140.00万股股份办理了解除质押手续。本次解除质押后，顾美芳女士累计质押公 司股份数量为500.00万股，占其所持股份的48.44%。 ...

Core Points - The company, Beijing Joinn Laboratory, has announced the convening of its second extraordinary general meeting of shareholders for 2025, scheduled for December 5, 2025, at 14:30 [1] - The meeting will utilize a combination of on-site and online voting methods, with the online voting system provided by the Shanghai Stock Exchange [1][2] - Shareholders must register to attend the meeting and can delegate their voting rights to a proxy if unable to attend in person [10][11] Meeting Details - The meeting will take place at the company's conference room located in Beijing Economic and Technological Development Zone [1] - Voting will be available through the Shanghai Stock Exchange's online voting system on the same day as the meeting, with specific time slots for trading system voting and internet voting [1][2] - Shareholders holding multiple accounts can vote through any of their accounts, but must ensure that their votes do not exceed their total voting rights [4][5] Voting Procedures - The company has outlined specific procedures for shareholders participating in the online voting, including identity verification for first-time users [3][4] - There are no proposals requiring separate voting for minority investors or involving related party transactions [3] - The company will provide reminders to shareholders about the meeting and voting through SMS and other means to ensure participation [7] Attendance and Registration - Only shareholders registered with the China Securities Depository and Clearing Corporation Limited as of the close of trading on the registration date are eligible to attend [8] - Personal shareholders must present valid identification, while corporate shareholders must provide documentation proving their legal representation [10] - Registration must be completed 24 hours prior to the meeting [10]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不 負 責，對 其 準 確 性 或 完 整 性 亦 不 發 表 任 何 聲 明，並 明 確 表 示，概 不 對 因 本 公 告 全部或任何部分內容而產生或因倚賴該等內容而引致的任何損失承擔任何責 任。 JOINN LABORATORIES (CHINA) CO., LTD. 北京昭衍新藥研究中心股份有限公司 （於 中 華 人 民 共 和 國 註 冊 成 立 的 股 份 有 限 公 司） （股 份 代 號：6127） 海外監管公告 本公告乃北京昭衍新藥研究中心股份有限公司（「本公司」）根據香港聯合交易 所有限公司證券上市規則第13.10B條 而 作 出。 附件為本公司於上海證券交易所網站刊登之 北京昭衍新藥研究中心股份有限公司 （1）關於召開2025年第二次臨時股東大會的通知 （2）2025年第二次臨時股東大會會議資料 承董事會命 北京昭衍新藥研究中心股份有限公司 馮宇霞 董事長 中 國 北 京，2025年 於11月14日 於 本 公 告 日 期，董 事 會 包 括 主 席 兼 執 行 董 事 馮 宇 霞 女 士、執 行 董 事 高 大 鵬 先 生 ...

JOINN Laboratories (China) Co., Ltd. 北京昭衍新藥研究中心股份有限公司 (A joint stock company incorporated in the People's Republic of China with limited liability) （於中華人民共和國註冊成立的股份有限公司） （Stock Code 股份代號：6127） NOTIFICATION LETTER 通知信函 Dear Non-Registered Shareholders, 17 November 2025 JOINN Laboratories (China) Co., Ltd. (the "Company") – Notice of publication of Circular in relation to (1) proposed amendments to the articles of association and proposed abolishment of the supervisory committee; (2) proposed amendments to ce ...