药品注册证书的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 宁波美诺华药业股份有限公司（以下简称"公司"）全资子公司宁波美诺华 天康药业有限公司（以下简称"美诺华天康"）于近日收到国家药品监督管理局 （以下简称"国家药监局"）核准签发的厄贝沙坦氢氯噻嗪片《药品注册证书》， 现将相关情况公告如下： 一、药品相关信息 | 证券代码：603538 | 证券简称：美诺华 | 公告编号：2025-105 | | --- | --- | --- | | 转债代码：113618 | 转债简称：美诺转债 | | 宁波美诺华药业股份有限公司 关于全资子公司获得厄贝沙坦氢氯噻嗪片 1、药品名称：厄贝沙坦氢氯噻嗪片 2、剂型：片剂 3、规格： 每片含厄贝沙坦 150mg，氢氯噻嗪 12.5mg。 4、申请事项：药品注册（境内生产） 5、注册分类：化学药品 4 类 6、受理号：CYHS2402184 7、药品批准文号：国药准字 H20255680 8、药品批准文号有效期：至 2030 年 10 月 13 日 9、上市许可持有人：宁波美诺华天康 ...

Core Viewpoint - Meinuo Pharma has received approval from the National Medical Products Administration for the production and sale of Irbesartan Hydrochlorothiazide tablets, enhancing its market competitiveness and expanding its cardiovascular product pipeline [1] Group 1 - Meinuo Pharma's wholly-owned subsidiary, Ningbo Meinuo TianKang Pharmaceutical Co., Ltd., has obtained the drug registration certificate for Irbesartan Hydrochlorothiazide tablets [1] - The drug is indicated for the treatment of primary hypertension, which addresses a significant health issue [1] - The approval marks a significant milestone for the company, allowing it to produce and sell the drug in the domestic market [1] Group 2 - The introduction of this product is expected to positively impact the company's operational development [1] - The approval enhances the company's product offerings in the cardiovascular segment, which is crucial for growth in this therapeutic area [1]

Core Insights - Meinuo Pharma (603538) announced that its wholly-owned subsidiary, Ningbo Meinuo TianKang Pharmaceutical Co., Ltd., has received the drug registration certificate for Irbesartan Hydrochlorothiazide Tablets from the National Medical Products Administration [1] Group 1 - The approved drug is indicated for the treatment of primary hypertension [1]

Core Viewpoint - Meinuo Pharma (603538.SH) has received approval from the National Medical Products Administration for its product, Irbesartan Hydrochlorothiazide Tablets, which is indicated for the treatment of primary hypertension [1] Group 1: Product Approval - Meinuo Pharma's wholly-owned subsidiary, Ningbo Meinuo TianKang Pharmaceutical Co., Ltd., has obtained the drug registration certificate for Irbesartan Hydrochlorothiazide Tablets from the National Medical Products Administration [1] - The combination of Irbesartan, an angiotensin II receptor antagonist, and Hydrochlorothiazide, a thiazide diuretic, is designed to provide a synergistic effect in lowering blood pressure within the recommended therapeutic dosage range [1]

Core Viewpoint - Meinuo Pharma (603538.SH) has received approval from the National Medical Products Administration for its product, Irbesartan Hydrochlorothiazide Tablets, which is indicated for the treatment of primary hypertension [1] Company Summary - Meinuo Pharma's wholly-owned subsidiary, Ningbo Meinuo TianKang Pharmaceutical Co., Ltd., has been granted a drug registration certificate for Irbesartan Hydrochlorothiazide Tablets [1] - The drug is a combination of the angiotensin II receptor antagonist Irbesartan and the thiazide diuretic Hydrochlorothiazide, which work synergistically to lower blood pressure within the recommended therapeutic dosage range [1]

Core Viewpoint - Meheco's subsidiary, Meheco Tiankang, has received approval from the National Medical Products Administration for the registration of Eprosartan Hydrochlorothiazide Tablets, which are used to treat primary hypertension [1] Company Summary - The approved drug is a combination of angiotensin II receptor antagonist Eprosartan and thiazide diuretic Hydrochlorothiazide [1] - Meheco Tiankang has invested 5.8747 million yuan in the research and development of this drug [1] Market Summary - The global sales forecast for Eprosartan Hydrochlorothiazide Tablets in 2024 is projected to be 817 million USD, with sales in China expected to reach 184 million USD [1]

Core Viewpoint - Meinuo Pharma has received approval from the National Medical Products Administration for the registration of Irbesartan Hydrochlorothiazide tablets, enhancing its market competitiveness and expanding its cardiovascular product pipeline [1] Group 1 - Meinuo Pharma's wholly-owned subsidiary, Ningbo Meinuo TianKang Pharmaceutical Co., Ltd., has obtained the drug registration certificate for Irbesartan Hydrochlorothiazide tablets [1] - The drug is indicated for the treatment of primary hypertension, which addresses a significant health issue [1] - The approval allows the company to produce and sell the drug in the domestic market, positively impacting its operational development [1]

Core Viewpoint - Meinuo announced that it will not adjust the conversion price of its convertible bonds, "Meinuo Convertible Bonds," during the upcoming board meeting scheduled for October 17, 2025 [1] Summary by Relevant Sections - **Board Decision**: The board of Meinuo has decided not to lower the conversion price of the "Meinuo Convertible Bonds" [1] - **Future Considerations**: The period for triggering the conversion price adjustment clause will restart from October 20, 2025. If the clause is triggered again, the board will decide whether to exercise the right to adjust the conversion price [1] - **Investor Advisory**: Investors are advised to pay attention to investment risks associated with this decision [1]

Core Viewpoint - Meihua announced the convening of its fifth board meeting on October 17, 2025, to discuss the proposal regarding not adjusting the conversion price of its convertible bonds [1] Group 1 - The fifth board meeting will be held in a hybrid format, combining in-person and communication methods [1] - The agenda includes the review of the proposal concerning the non-adjustment of the convertible bond conversion price [1]

| | | 宁波美诺华药业股份有限公司 关于不向下修正"美诺转债"转股价格的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示: 截至 2025 年 10 月 17 日，宁波美诺华药业股份有限公司（以下简称"公 司"）股票已出现在任意连续三十个交易日中至少有十五个交易日的收盘价格低 于当期转股价格（25.68 元/股）90%，即低于 23.11 元/股（保留两位小数）的 情形，触发"美诺转债"转股价格向下修正条款。 2025 年 10 月 17 日，公司召开第五届董事会第十七次会议审议通过《关 于不向下修正可转换公司债券转股价格的议案》，公司董事会决定本次不向下修 正"美诺转债"转股价格。下一触发转股价格修正条款的期间从 2025 年 10 月 20 日重新起算，若再次触发"美诺转债"转股价格的向下修正条款，届时公司 董事会将决定是否行使"美诺转债"的转股价格向下修正权利，请广大投资者注 意投资风险。 一、可转换公司债券基本情况 （一）可转换公司债券发行上市概况 经中国证券监督管理委员会《关于核准宁波美诺华药业 ...