Core Viewpoint - Bid Pharma's stock increased by 5.1% to 74.18 CNY per share, with a total market capitalization of 6.742 billion CNY as of September 24 [1] Company Overview - Shanghai Bid Pharma Technology Co., Ltd. was established on April 27, 2007, and listed on October 11, 2022 [1] - The company focuses on the front end of the new drug research and development industry chain, providing innovative drug molecular building blocks and scientific reagents [1] - Main business revenue composition: - Heterocyclic compounds: 43.26% - Aromatic compounds: 23.32% - Aliphatic compounds: 16.36% - Catalysts and ligands: 10.57% - Life science reagents: 6.49% [1] Fund Holdings - Guodu Securities has a fund that heavily invests in Bid Pharma, with Guodu Jucheng (011389) holding 7,000 shares, representing 3.98% of the fund's net value [2] - The fund has generated a floating profit of approximately 25,200 CNY as of the report date [2] Fund Manager Performance - Guodu Jucheng (011389) has three fund managers: - Liao Xiaodong: 5 years and 134 days of tenure, with a best return of -24.14% and worst return of -63.61% [3] - Zhang Xiaolei: 6 years and 284 days of tenure, with a best return of 80.09% and worst return of -23.54% [3] - Gong Yongjin: 1 year and 175 days of tenure, with a consistent return of 7.81% [3]

Core Viewpoint - Bid Pharma experienced a decline of 5.08% on September 23, with a stock price of 70.03 CNY per share and a total market capitalization of 6.365 billion CNY [1] Company Overview - Shanghai Bid Pharma Technology Co., Ltd. was established on April 27, 2007, and went public on October 11, 2022. The company focuses on the front end of the new drug research and development industry chain, providing innovative drug molecular building blocks and scientific reagents [1] - The main business revenue composition includes: - Heterocyclic compounds: 43.26% - Aromatic compounds: 23.32% - Aliphatic compounds: 16.36% - Catalysts and ligands: 10.57% - Life science reagents: 6.49% [1] Shareholder Information - Among the top ten circulating shareholders of Bid Pharma, a fund under China Europe Fund holds a significant position. The China Europe Medical Health Mixed A Fund (003095) reduced its holdings by 193,100 shares in Q2, now holding 4.2526 million shares, which is 9.84% of the circulating shares. The estimated floating loss today is approximately 15.9471 million CNY [2] - The China Europe Medical Health Mixed A Fund was established on September 29, 2016, with a latest scale of 15.638 billion CNY. Year-to-date return is 31.45%, ranking 2835 out of 8172 in its category; the one-year return is 50.82%, ranking 3170 out of 7995; and since inception, the return is 126.87% [2] Fund Manager Performance - The fund manager of the China Europe Medical Health Mixed A Fund is Ge Lan, who has been in the position for 10 years and 241 days, managing assets totaling 39.908 billion CNY. The best fund return during her tenure is 125.52%, while the worst is -35.13% [3] - Another fund, China Europe Jiaxuan Mixed A (010947), holds 328,600 shares of Bid Pharma, accounting for 2% of the fund's net value, ranking as the fifth-largest holding. The estimated floating loss today is about 1.2322 million CNY [4] - The fund manager of China Europe Jiaxuan Mixed A is Wang Jian, who has been in the role for 15 years and 335 days, managing assets of 6.565 billion CNY. The best return during his tenure is 200.87%, while the worst is -22.48% [5]

Company Overview - Bid Pharma is located in Yangpu District, Shanghai, and was established on April 27, 2007. The company went public on October 11, 2022. Its main business focuses on the front end of new drug research and development, providing innovative drug molecular building blocks and scientific reagents [1]. Business Composition - The revenue composition of Bid Pharma includes: - 43.26% from molecular building block heterocyclic compounds - 23.32% from molecular building block aromatic compounds - 16.36% from molecular building block aliphatic compounds - 10.57% from catalysts and ligands - 6.49% from life science reagents [1]. Market Performance - On September 23, Bid Pharma's stock fell by 5.08%, closing at 70.03 CNY per share, with a trading volume of 36.31 million CNY and a turnover rate of 1.17%. The total market capitalization is 6.365 billion CNY [1]. Fund Holdings - Morgan Stanley's fund holds a significant position in Bid Pharma, with the "Morgan Stanley Youyue Anhe Mixed A" fund (009893) owning 68,300 shares, representing 5.92% of the fund's net value, making it the second-largest holding. The estimated floating loss today is approximately 256,300 CNY [2]. Fund Performance - The "Morgan Stanley Youyue Anhe Mixed A" fund was established on September 24, 2020, with a current size of 28.9066 million CNY. Year-to-date, it has returned 22.41%, ranking 4046 out of 8172 in its category. Over the past year, it has returned 41.52%, ranking 4017 out of 7995. Since inception, it has incurred a loss of 27.95% [2]. Fund Management - The fund manager of "Morgan Stanley Youyue Anhe Mixed A" is Zhao Weijie, who has been in the position for 4 years and 205 days. The total asset size of the fund is 305 million CNY, with the best return during his tenure being 28.14% and the worst being -30% [3].

Market Performance - On September 22, the medical services sector rose by 0.18% compared to the previous trading day, with Haoyuan Pharmaceutical leading the gains [1] - The Shanghai Composite Index closed at 3828.58, up 0.22%, while the Shenzhen Component Index closed at 13157.97, up 0.67% [1] Top Gainers in Medical Services - Haoyuan Pharmaceutical (688131) closed at 79.32, up 7.49% with a trading volume of 76,500 shares and a transaction value of 592 million [1] - Bid Pharma (688073) closed at 73.78, up 5.52% with a trading volume of 14,500 shares and a transaction value of 104 million [1] - Heyuan Biotechnology (688238) closed at 8.10, up 3.98% with a trading volume of 218,700 shares and a transaction value of 174 million [1] Top Losers in Medical Services - Pulangsi (301257) closed at 49.10, down 4.21% with a trading volume of 43,300 shares and a transaction value of 216 million [2] - Innovative Medical (002173) closed at 21.53, down 4.18% with a trading volume of 612,900 shares and a transaction value of 134 million [2] - ST Zhongzhu (600568) closed at 2.02, down 3.81% with a trading volume of 226,400 shares and a transaction value of 46 million [2] Capital Flow in Medical Services - On the same day, the medical services sector experienced a net outflow of 643 million from institutional investors, while retail investors saw a net inflow of 438 million [2] - The sector's overall capital flow indicates a mixed sentiment, with institutional investors withdrawing funds while retail investors increased their positions [2] Individual Stock Capital Flow - For WuXi AppTec (603259), the net inflow from institutional investors was 27.8 million, while retail investors had a net outflow of 29.7 million [3] - Haoyuan Pharmaceutical (688131) saw a net inflow of 17.6 million from institutional investors but a net outflow of 13.9 million from retail investors [3] - Bid Pharma (688073) had a minimal net inflow of 120,000 from institutional investors, with retail investors experiencing a net outflow of 768,640 [3]

Core Viewpoint - The Chinese innovative drug industry is gradually catching up with Europe and the United States in terms of technology, with some targets and technical pathways already leading globally. The number and value of new drugs authorized for overseas markets continue to increase, leading to world-class pricing and non-linear investment elasticity. The domestic market is experiencing strong growth in demand, with domestic new drug sales continuing to rise, and several innovative pharmaceutical companies have turned losses into profits, entering a stable growth phase [2]. Group 1: Innovative Drugs - The innovative drug sector is witnessing a significant increase in sales driven by strong domestic demand, with a number of innovative companies achieving profitability [2]. - The trend of domestic innovative drugs going overseas is accelerating, with increasing numbers and values of new drug authorizations [2]. - The pricing power of innovative drugs is improving, reflecting the global competitiveness of Chinese pharmaceutical companies [2]. Group 2: High-Value Medical Consumables - The orthopedic sector is expected to see mild price reductions due to continued domestic substitution and accelerated overseas business progress [2]. - The neurosurgery and neurointervention fields are experiencing stable growth post-collection, with new products being launched [2]. - The high-value consumables market is expected to benefit from ongoing domestic replacement and the introduction of new products [2]. Group 3: Medical Devices - The medical device sector is seeing a recovery in bidding prices, with ongoing high-speed growth in bidding data this year [2]. - Companies are entering a phase of inventory reduction, with performance expected to improve in the second half of the year [2]. - The low-value consumables sector is experiencing product upgrades and accelerated expansion into overseas markets [2]. Group 4: Blood Products - The supply side of the blood products industry is concentrating on central state-owned enterprises, gradually clearing the competitive landscape [2]. - The demand side is expected to see continuous upgrades to new products, with industry sentiment gradually improving [2]. Group 5: API (Active Pharmaceutical Ingredients) - The API sector is benefiting from the end of a capital expenditure peak, with three growth logic points driving upward trends: new high-end market products, integrated consolidation and overseas expansion, and cost-leading CDMO [2]. - Leading companies in the API sector are expected to see explosive growth in revenue and profits [2]. Group 6: CXO (Contract Research Organization) - The CXO sector is witnessing a recovery in A+H financing activity, with multiple significant business developments enhancing market confidence [2]. - The focus is on optimizing the supply-side landscape and increasing market share for leading CRO companies [2]. Group 7: Traditional Chinese Medicine and Retail Pharmacy - The traditional Chinese medicine sector is showing signs of recovery, with friendly pricing for new drugs and ongoing observation of collection progress [2]. - The retail pharmacy sector is influenced by the pace of supply-side clearing and business model upgrades, with expectations of increased store closures in the second half of 2025 [2]. Group 8: Research and Development Services - The domestic innovative drug business development is heating up, likely driving downstream demand recovery [2]. - The overseas market presents significant growth opportunities for domestic companies, leveraging cost-effectiveness and service differentiation [2].

Core Viewpoint - The Chinese innovative drug industry is gradually catching up with Europe and the United States in terms of technology, with some targets and technical pathways already leading globally. The number and value of new drugs authorized for overseas markets continue to increase, leading to world-class pricing and non-linear investment elasticity. The domestic market is experiencing strong growth in demand, with domestic new drug sales continuing to rise, and several innovative pharmaceutical companies have turned losses into profits, entering a stable growth phase [2]. Group 1: Innovative Drugs - The innovative drug sector is witnessing a significant increase in sales driven by strong domestic demand, with a number of innovative companies achieving profitability [2]. - The trend of domestic innovative drugs going overseas is accelerating, with increasing numbers and values of new drug authorizations [2]. - The industry is positioned for a "Davis double" effect, where both performance and valuation are expected to improve [2]. Group 2: High-Value Medical Consumables - The orthopedic sector is expected to see mild price reductions, while domestic replacements continue to grow, and overseas business progresses rapidly [2]. - The neurosurgery and neurointervention fields are stabilizing after centralized procurement, with new products expected to contribute to growth [2]. Group 3: Medical Devices - The medical device sector is experiencing a high-speed growth in bidding data, with companies entering a destocking phase, which is expected to improve performance in the second half of the year [2]. - The low-value consumables sector is seeing continuous product upgrades and accelerated expansion into overseas markets [2]. Group 4: Blood Products - The supply side of the blood products industry is increasingly concentrated among state-owned enterprises, leading to a clearer competitive landscape [2]. - The demand side is expected to upgrade towards new products, gradually improving the industry's overall health [2]. Group 5: API (Active Pharmaceutical Ingredients) - The industry is at an upward turning point due to the end of a capital expenditure peak, combined with three growth drivers: new high-end market products, integrated consolidation and overseas expansion, and cost-leading CDMO [2]. - Leading companies are expected to see explosive growth in revenue and profits in the medium term [2]. Group 6: CXO (Contract Research Organization) - The CXO sector is seeing a revival in A+H financing activity, with multiple significant business developments enhancing market confidence [2]. - The focus is on optimizing the supply-side landscape and increasing market share for leading CRO companies [2]. Group 7: Traditional Chinese Medicine and Retail Pharmacy - The traditional Chinese medicine sector is showing signs of recovery, with friendly pricing for new drugs, while the retail pharmacy sector is influenced by supply-side adjustments and business model upgrades [2]. - The performance of offline pharmacies is expected to improve in the second half of 2025, with leading chains like YaoXingTang making progress in store upgrades [2]. Group 8: Research Reports - A series of in-depth research reports on various companies and sectors within the pharmaceutical and medical device industries have been published, highlighting their growth potential and market positioning [3][4].

Core Insights - The medical services sector experienced a slight increase of 0.29% on September 16, with Chengda Pharmaceutical leading the gains [1] - The Shanghai Composite Index closed at 3861.87, up 0.04%, while the Shenzhen Component Index closed at 13063.97, up 0.45% [1] Medical Services Sector Performance - Chengda Pharmaceutical (301201) closed at 33.32, with a significant increase of 15.25% and a trading volume of 157,100 shares, amounting to a transaction value of 508 million yuan [1] - Haocen Medical (002622) saw a rise of 10.10%, closing at 4.25 with a trading volume of 993,200 shares, totaling 409 million yuan [1] - Aoyang Health (002172) increased by 10.00%, closing at 4.73 with a trading volume of 87,500 shares, amounting to 41.39 million yuan [1] - Bid Pharma (688073) rose by 6.48%, closing at 74.73 with a trading volume of 26,000 shares, totaling 192 million yuan [1] - Yikang Biological (688046) increased by 5.56%, closing at 19.75 with a trading volume of 79,600 shares, amounting to 158 million yuan [1] - Other notable performers include Haoyuan Pharmaceutical (688131) with a 4.44% increase, closing at 78.28, and Xinlicheng (002219) with a 3.46% increase, closing at 2.39 [1] Fund Flow Analysis - The medical services sector saw a net outflow of 228 million yuan from institutional investors, while retail investors contributed a net inflow of 59.64 million yuan [3] - Speculative funds recorded a net inflow of 168 million yuan into the sector [3]

Investment Rating - The report does not provide specific ratings for the pharmaceutical industry, but indicates a neutral outlook for certain segments such as biopharmaceuticals and other pharmaceutical therapies [2]. Core Insights - The pharmaceutical industry is showing signs of stabilization and recovery, with a clear upward trend in performance [12]. - The CXO sector achieved a revenue of 47.096 billion yuan in the first half of 2025, representing a year-on-year growth of 13.25%, and a net profit of 11.743 billion yuan, up 61.19% year-on-year [12][10]. - The report highlights improvements in operational efficiency and cost reduction as key factors driving profit growth [12]. Summary by Sections 1. Industry Overview - The industry is gradually stabilizing, with a clear trend towards recovery. The CXO sector's revenue and profit have shown significant growth in the first half of 2025 [12][10]. - The average revenue per employee increased to 411,100 yuan, a year-on-year increase of 12.62%, while average profit per employee rose to 114,000 yuan, up 52.41% [4][25]. 2. Demand and Supply Dynamics - Demand is stabilizing with a slight recovery in orders, as indicated by a 3.71% year-on-year increase in contract liabilities and prepayments, reaching 7.549 billion yuan in the first half of 2025 [4][33]. - Supply-side indicators show a modest increase in capacity construction, with fixed assets growing by 5.81% year-on-year to 47.274 billion yuan [36]. 3. Financial Environment - The report notes the commencement of a Federal Reserve rate-cutting cycle, which is expected to enhance market liquidity [5][42]. - The A+H share innovation drug index has seen significant increases, which may positively influence local financing conditions [5]. 4. Company Recommendations - The report suggests focusing on clinical CROs benefiting from domestic innovation drug support policies, such as Yangguang Nuohuo and Nuosige [61]. - It also highlights companies with strong overseas business prospects, like Haoyuan Pharmaceutical and Bide Pharmaceutical, as well as those involved in weight loss drugs and Alzheimer's treatments [61]. 5. Performance Forecasts - For the company Hongbo Pharmaceutical, revenue is projected to grow from 739 million yuan in 2025 to 1.299 billion yuan by 2027, with a corresponding net profit increase [66]. - Haoyuan Pharmaceutical is expected to achieve revenues of 28.48 billion yuan by 2027, reflecting a growth rate of 25.47% [70]. 6. Market Trends - The CXO index has significantly outperformed the market, with a year-to-date increase of 58.32% as of September 11, 2025 [54]. - The report emphasizes the importance of monitoring changes in U.S. interest rate policies and geopolitical factors affecting the industry [5].

Group 1 - Tianhua New Energy plans to acquire 75% equity of Suzhou Tianhua Times for 1.254 billion yuan, aiming to transfer lithium resource investment to the listed company and eliminate potential competition risks [1] - Wan'an Technology intends to invest 20 million yuan in Tongchuan Technology through capital increase, acquiring 2.72% equity, focusing on core components for robotics [2] - Bid Pharma shareholders plan to reduce their holdings by no more than 1% of the company's total shares within three months [3] Group 2 - Borui Data shareholders plan to reduce their holdings by no more than 5.4% of the company's total shares, with specific reductions from key personnel [4] - Tonglian Precision announces that shareholders intend to reduce their holdings by no more than 3% of the company's total shares through various trading methods [5] - Zhongchao Holdings signs a strategic cooperation agreement with Hefei Intelligent Robot Research Institute to collaborate on technology and industrial applications in robotics [6] Group 3 - Guodun Quantum plans to sign sales contracts with China Telecom Quantum Group, with expected amounts of 12.144 million yuan and 63.054 million yuan for different projects [7] - Jingjiawei signs a strategic cooperation agreement with Anchaoyun, ensuring compatibility between its GPU products and Anchaoyun's software, supporting high-performance cloud desktop solutions [8] - *ST Dongtong faces potential forced delisting due to significant violations, with stock risk warnings implemented following regulatory actions [9]

Summary of Key Points Core Viewpoint - On September 12, 18 listed companies disclosed share reduction plans, with no companies announcing share increases on that day [1]. Group 1: Companies and Their Reduction Plans - Mars Man plans to reduce shares by up to 2.94% by a concerted action of its controlling shareholder [2]. - Minfa Aluminum's shareholder Huang Tianhu plans to reduce shares by up to 1% [2]. - Hengtian Hailong's shareholder China Hengtian Group intends to reduce up to 3% of the company's shares [2]. - Zhiwei Intelligent's controlling shareholder Guo Xuhui plans to reduce up to 7.5 million shares [2]. - Peking University Medicine plans to reduce 3% of its shares [2]. - Jin'an Guoji's controlling shareholder Donglin Investment and its concerted parties plan to reduce up to 3% [2]. - *ST Yitong's shareholder plans to reduce up to 2.96% of the company's shares [2]. - International Composite's shareholder Yunnan Yunxi plans to reduce up to 1.5% of the company's shares [2]. - Donghua Software's controlling shareholder Xue Xiangdong plans to reduce up to 1.4% of the company's shares [2]. - Huali Group's controlling shareholder Hong Kong Junyao plans to reduce up to 1.5% of the company's shares [2]. - Warner Pharmaceutical's shareholder Xu Xiaoqiang has cumulatively reduced 1.2961 million shares from September 1 to September 12 [2]. - Bidder Pharmaceutical's shareholders plan to collectively reduce up to 1% of the company's shares [2]. - Borui Data's shareholders plan to collectively reduce up to 5.4% of the company's shares [2]. - Tonglian Precision's shareholders Shenchuang Investment and its concerted parties plan to reduce up to 3% of the company's shares [2]. - Juguang Technology's controlling shareholder and its concerted parties have recently reduced 868,800 shares [2]. - Huat Gas's shareholders plan to reduce up to 2% of the company's shares [2]. - Beileisong's shareholder Wang Qiaoqing plans to reduce up to 1% of the company's shares [2]. - New Classics' shareholder Chen Liping plans to reduce up to 1.2 million shares [2].