Group 1 - Huapei Power received a project intention letter from a domestic new energy vehicle company for a thermal management system PTC water heater, with an estimated sales amount of approximately 9 million yuan over a 5-year lifecycle starting from 2026 [1] - Antu Biotech obtained medical device registration certificates for products including "Cytomegalovirus IgM Antibody Test Kit" [1][2] - Yihong Technology adjusted the upper limit of its share repurchase price to 65.04 yuan per share, with a total repurchase amount of 6.9583 million yuan for 198,000 shares [2] Group 2 - Aihui Long received a medical device registration certificate for the Hepatitis B virus core antibody detection kit, valid until May 28, 2030 [2][3] - Quanxin Co. plans to engage in commodity futures hedging to mitigate raw material price fluctuations, with a maximum guarantee amount of 8 million yuan [3] - Jiahua Intelligent plans to lease idle assets in Dongguan for a total rental amount of approximately 6.3193 million yuan over 6 years [3] Group 3 - Qianjiang Biochemical announced the resignation of its chairman and a director, with a new chairman to be elected [4][5] - Aerospace Morning Light was suspended from participating in military procurement activities due to violations, with internal investigations underway [6] - Guang'an Aizhong intends to establish a fund with a total scale of 70.7 million yuan, focusing on distributed wind and solar power generation [7] Group 4 - Zhejiang Medicine plans to use up to 1 billion yuan of idle funds for entrusted wealth management, with a maximum investment period of 12 months [10] - Hengrui Medicine's subsidiary received approval for clinical trials of HRS9531 injection, aimed at treating type 2 diabetes patients [11] - Taiji Co. announced the purchase of 10 million yuan in wealth management products, with a minimum holding period of 6 months [12] Group 5 - Hong Kong-listed company Huichuang Pharmaceutical received approval for the clinical trial of a spray for treating primary premature ejaculation [26][27] - Haichuang Pharmaceutical's new drug application for a prostate cancer treatment was approved by the National Medical Products Administration [28] - Zhuhai Guanyu was selected as a designated supplier for low-voltage lithium batteries by SAIC Volkswagen [29] Group 6 - Huayi Technology opened a tax refund service for overseas travelers, enhancing its retail offerings [32] - Baobian Electric plans to transfer 90% of its subsidiary's shares for 137 million yuan [33] - Yiwei Communication intends to invest 100 million yuan to establish a wholly-owned subsidiary to enhance its strategic layout [34]

证券代码：688193 证券简称：仁度生物 公告编号：2025-029 上海仁度生物科技股份有限公司 关于自愿披露公司相关产品 取得医疗器械注册证的公告 特此公告。 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 上海仁度生物科技股份有限公司 一、产品注册证具体情况 | 产品名称 | 注册证书编号 | 注册类别 | | 注册证有效期 | | --- | --- | --- | --- | --- | | 乙型肝炎病毒核酸测定试 | 国械注准 | 三类 | 2025年5月29日至2030 | | | 剂盒（DNA 捕获探针法） | 20253401041 | | 年 | 月 日 5 28 | 二、对公司的影响 上述产品系公司血源传染病系列的新产品，通过对乙型肝炎患者血中 HBV DNA 基线水平和变化情况的监测，评估抗病毒治疗的应答和治疗效果，与公司 已有的 HBV RNA 检测形成"双维"检测，实现了"乙丙艾"三大传染病全自动高 敏检测产品线全覆盖。 三、风险提示 上述注册证书涉及的产品实际销售情况取决于未来市场推广效果， ...

Core Viewpoint - The company has received regulatory approval for its hepatitis B virus nucleic acid testing kit, which is expected to enhance its product line and market presence in the infectious disease testing sector [1] Group 1: Product Approval - The hepatitis B virus nucleic acid testing kit (DNA capture probe method) has been granted a Class III registration certificate with a registration number of 202.53 billion [1] - The registration certificate is valid from May 29, 2025, to May 28, 2030 [1] Group 2: Product Features and Market Impact - This new product is part of a series for blood-borne infectious diseases, allowing for the monitoring of HBV DNA baseline levels and changes in patients, which aids in evaluating antiviral treatment responses and effectiveness [1] - The product complements the existing HBV RNA testing, creating a comprehensive "dual-dimension" testing approach and covering the full automated high-sensitivity testing product line for hepatitis B, C, and E [1] - The actual sales performance of this product will depend on future marketing efforts, and its impact on the company's future performance remains uncertain [1]

Group 1: Hologene (HOLX) - Hologene is a major player in the medical device sector, recently rejecting a $16 billion acquisition offer from TPG and Blackstone, which would have been one of the largest leveraged buyouts in the global medical field by 2025 [1] - The acquisition offer was priced at $70 to $72 per share, significantly above Hologene's closing price of $54.28 on May 24, indicating a strong market interest in the company [1] - Hologene remains committed to its long-term development strategy, believing that its technological and market advantages will lead to a future value exceeding $100 billion [1] Group 2: Rendu Biotech (仁度生物) - Rendu Biotech, listed on the STAR Market, is emerging as a potential leader in the RNA testing field, with its founder having extensive experience at Hologene [2] - The company has developed RNA testing technology over the past decade, supported by a strong R&D team with nearly 50% of members holding master's or doctoral degrees [2] - Rendu has established a robust patent portfolio with 62 patents, including 40 invention patents, showcasing its commitment to innovation in RNA diagnostics [2] Group 3: Market Position and Challenges - Rendu's CT and NG testing products hold a significant market share domestically, with a reported revenue of 177 million yuan in 2024, reflecting a year-on-year growth of 7.87% [3] - The company is actively developing various projects, including an anticipated HPV testing product that aims to challenge foreign market dominance [3] - Despite its technological strengths, Rendu faces challenges in market recognition, as RNA testing is still a nascent field in China, with many institutions and patients favoring traditional methods [3]

Core Viewpoint - The recent revision of the Infectious Disease Prevention Law in China emphasizes the need for standardized isolation treatment for infectious tuberculosis (TB) patients, marking a significant shift towards a modernized prevention and control system in TB management starting from September 1, 2025 [1][2][3]. Group 1: Policy Changes - The new law mandates standardized isolation treatment for infectious TB patients and screening of close contacts, providing a legal basis for medical institutions to implement these measures [2][3]. - The National TB Prevention and Control Plan (2024-2030) and the Guangxi TB Prevention and Control Plan (2025-2030) highlight the importance of reducing transmission in community and hospital settings through effective isolation [2][3]. Group 2: Technological Advancements - The TB-RNA nucleic acid testing system launched by Rendu Biotech is the only rapid live bacteria detection product in China, enhancing the scientific and efficient isolation treatment of infectious TB patients [1][4]. - TB-RNA technology offers unique advantages in accurately identifying live bacteria, which is crucial for controlling transmission and adjusting treatment plans, overcoming limitations of traditional methods [4][5]. Group 3: Efficiency and Economic Benefits - TB-RNA testing significantly reduces the time required for diagnosis, with results available in hours compared to weeks for traditional culture methods, thus shortening patient isolation periods and improving resource utilization [5][6]. - The integration of TB-RNA technology into diagnostic protocols is expected to yield positive health economic benefits by reducing hospitalization days and minimizing unnecessary isolation due to false positives from DNA testing [7].

Core Viewpoint - The report outlines the continuous supervision work conducted by China International Capital Corporation for Shanghai Rendu Biotechnology Co., Ltd. during the 2024 fiscal year, emphasizing compliance with regulations and the company's operational integrity [1][2][3]. Continuous Supervision Work - The sponsor has established and effectively implemented a continuous supervision system, along with a corresponding work plan [1]. - A sponsorship agreement has been signed with Rendu Biotechnology, clarifying the rights and obligations of both parties during the supervision period [2]. - Continuous supervision is conducted through daily communication, regular visits, on-site inspections, and due diligence [3]. Compliance and Governance - Rendu Biotechnology has adhered to legal and regulatory requirements, ensuring that its directors and senior management comply with relevant laws and regulations [4][5]. - The company has established effective internal control systems, including financial management and internal audit procedures, which have been verified by the sponsor [7]. - The sponsor has reviewed the company's information disclosure documents to ensure there are no false records or misleading statements [6]. Financial Performance - For the fiscal year 2024, Rendu Biotechnology reported a revenue of 177.35 million, a 7.87% increase from 164.41 million in 2023 [18]. - The net profit attributable to shareholders was -7.81 million, a significant decline from 23.33 million in 2023 [18]. - The company has faced challenges in maintaining profitability, with a notable decrease in net assets and total assets compared to the previous year [19]. Industry Context - The in vitro diagnostic industry, particularly the molecular diagnostics sector, is experiencing rapid growth, driven by government support and increasing market demand [11][13]. - Rendu Biotechnology focuses on RNA molecular diagnostics, which offers higher specificity and sensitivity compared to DNA diagnostics, positioning the company favorably in the market [22]. - The company has established a strong market presence, particularly in the reproductive health sector, with a market share of 30.4% in the sexually transmitted infection diagnostics segment [24]. Risks and Challenges - The company faces risks related to significant declines in performance due to macroeconomic factors and changes in market demand for molecular diagnostics [9]. - Rendu Biotechnology must continuously innovate and develop new products to maintain its competitive edge in a technology-driven industry [10]. - The company is also challenged by the need to comply with evolving regulatory standards and the potential impact of international market dynamics [12][15]. Research and Development - Rendu Biotechnology has increased its R&D investment, focusing on the development of new products and technologies, including a digital micro-droplet RNA amplification detection system [26]. - The company has received multiple patents and regulatory approvals for its innovative products, enhancing its competitive position in the market [27][28]. - Ongoing projects cover a wide range of diagnostic areas, including reproductive health, blood-borne pathogens, and cancer diagnostics [27].

Meeting Overview - The shareholders' meeting of Shanghai Rendu Biotechnology Co., Ltd. was held on May 22, 2025, at the company's conference room [1] - The meeting was attended by 29 ordinary shareholders, representing 24,640,020 voting rights, which accounts for 63.6552% of the total voting rights [1] Voting Results - All non-cumulative voting proposals were approved with significant majority support: - Proposal 1: 24,628,105 votes in favor (99.9516%), 11,915 votes against (0.0484%) [1] - Proposal 2: 24,627,022 votes in favor (99.9472%), 12,998 votes against (0.0528%) [2] - Proposal 3: 24,628,105 votes in favor (99.9516%), 11,915 votes against (0.0484%) [2] - Proposal 4: 21,783,210 votes in favor (99.9404%), 12,998 votes against (0.0596%) [2] - Proposal 5: 21,779,810 votes in favor (99.9248%), 12,998 votes against (0.0596%), and 3,400 abstentions (0.0156%) [2] Legal Compliance - The meeting's procedures, including the qualifications of attendees and voting processes, complied with the Company Law and the company's articles of association, as confirmed by the attending lawyers [3]

| 序号 | 工作内容 | 持续督导情况 | | --- | --- | --- | | | 员的行为规范等。 | | | | 督导上市公司建立健全并有效执行内控制 | | | | 度，包括但不限于财务管理制度、会计核算 | 保荐机构对仁度生物的内控制度的设计、实 | | | 制度和内部审计制度，以及募集资金使用、 | 施和有效性进行了核查，仁度生物的内控制 | | 8 | 关联交易、对外担保、对外投资、衍生品交 | 度符合相关法规要求并得到了有效执行，能 | | | 易、对子公司的控制等重大经营决策的程序 | 够保证公司的规范运营。 | | | 与规则等。 | | | | 督导上市公司建立健全并有效执行信息披露 | | | | 制度，审阅信息披露文件及其他相关文件， | 保荐机构督促仁度生物依照相关规定健全和 | | 9 | 并有充分理由确信上市公司向上海证券交易 | 完善信息披露制度并严格执行，审阅信息披 | | | 所提交的文件不存在虚假记载、误导性陈述 | 露文件及其他相关文件。 | | | 或重大遗漏。 对上市公司的信息披露文件及向中国证监 | | | | 督促上市公司予以更正或补充，上市公司不 | ...

北京 BEIJING · 上海 SHANGHAI · 深圳 SHENZHEN · 香港 HONG KONG · 广州 GUANGZHOU · 西安 XI'AN 致:上海仁度生物科技股份有限公司 北京市嘉源律师事务所 北京市嘉源律师事务所 关于上海仁度生物科技股份有限公司 2024 年年度股东大会的 法律意见书 西城区复兴门内大街 158 号远洋大厦 4 楼 中国 · 北京 劃师事务所 YUAN LAW OFFICES 关于上海仁度生物科技股份有限公司 2024 年年度股东大会的 法律意见书 嘉源(2025)-04-358 北京市嘉源律师事务所(以下简称"本所")接受上海仁度生物科技股份有 限公司(以下简称"公司")的委托,根据《中华人民共和国公司法》(以下简称 "《公司法》")、《上市公司股东会规则》(以下简称"《股东会规则》")等现行有 效的法律、行政法规、部门规章、规范性文件(以下简称"法律法规")以及《上 海仁度生物科技股份有限公司章程》(以下简称"《公司章程》")的有关规定,指 派本所律师对公司 2024年年度股东大会(以下简称" 本次股东大会")进行见证, 并依法出具本法律意见书。 为出具本法律意见 ...

证券代码：688193 证券简称：仁度生物 公告编号：2025-028 上海仁度生物科技股份有限公司 2024年年度股东大会决议公告 本公司董事会及全体董事保证公告内容不存在任何虚假记载、误导性陈述或 者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 重要内容提示： 本次会议是否有被否决议案：无 一、 会议召开和出席情况 （一） 股东大会召开的时间：2025 年 5 月 22 日 （二） 股东大会召开的地点：公司会议室 事推选董事于明辉女士主持会议。会议采取现场投票和网络投票相结合的表决方 式。本次股东大会的召集和召开程序、出席会议人员的资格和召集人资格、会议 的表决程序和表决结果均符合《中华人民共和国公司法》及《上海仁度生物科技 股份有限公司章程》的规定。 （五） 公司董事、监事和董事会秘书的出席情况 1、 公司在任董事7人，出席7人； 2、 公司在任监事3人，出席3人； 3、董事会秘书蔡廷江先生出席了本次会议；其他高管均列席本次会议。 二、 议案审议情况 （一） 非累积投票议案 （三） 出席会议的普通股股东、特别表决权股东、恢复表决权的优先股股东及 其持有表决权数量的情况： | 1、出席会 ...