上海仁度生物科技股份有限公司2025 年半年度报告 公司代码：688193 公司简称：仁度生物 上海仁度生物科技股份有限公司 2025 年半年度报告 1 / 190 上海仁度生物科技股份有限公司2025 年半年度报告 重要提示 一、 本公司董事会、监事会及董事、监事、高级管理人员保证半年度报告内容的真实性、准确 性、完整性，不存在虚假记载、误导性陈述或重大遗漏，并承担个别和连带的法律责任。 二、 重大风险提示 公司已在本报告中详细阐述公司在经营过程中可能面临的各种风险及应对措施，敬请查阅本 报告第三节"管理层讨论与分析"之"五、风险因素" 三、 公司全体董事出席董事会会议。 四、 本半年度报告未经审计。 五、 公司负责人居金良、主管会计工作负责人蔡廷江及会计机构负责人（会计主管人员）蔡廷 江声明：保证半年度报告中财务报告的真实、准确、完整。 六、 董事会决议通过的本报告期利润分配预案或公积金转增股本预案 □适用 √不适用 七、 是否存在公司治理特殊安排等重要事项 □适用 √不适用 八、 前瞻性陈述的风险声明 √适用 □不适用 本报告所涉及公司未来计划，发展战略等前瞻性陈述，不构成对投资者的实质承诺，敬请投 资 ...

Group 1 - Multiple listed companies are developing detection solutions for Chikungunya virus, including Kingmed Diagnostics, Wanfu Biology, and Shengxiang Biology [1][2] - Kingmed Diagnostics has established a comprehensive platform for serological, fluorescent PCR, and sequencing tests to accurately identify the Chikungunya virus, aiding in clinical diagnosis [1] - Wanfu Biology has responded to the recent guidelines from the National Disease Control Bureau by developing several detection products that create a closed-loop system for rapid screening, precise detection, and monitoring [1] - Shengxiang Biology has introduced a dual-platform solution combining rapid nucleic acid testing and sequencing for precise tracing, with a detection time of 25 to 45 minutes and high sensitivity [1] Group 2 - According to a report by Everbright Securities, several domestic listed companies, including Da'an Gene, Wanfu Biology, Shengxiang Biology, Zhijiang Biology, Shuoshi Biology, Mingde Biology, and Rendu Biology, have launched Chikungunya virus detection solutions [2]

MACD金叉信号形成，这些股涨势不错！ 据北京日报，中国疾控中心艾防中心等团队完成我国首个复制型天坛痘苗载体艾滋病疫苗I期临床试 验。该研究创新性采用曾用于消灭天花的"天坛株"痘苗病毒为载体，试验验证了该方案的安全性且能激 发有效免疫反应。这标志着我国在艾滋病疫苗研发领域取得重要进展。 受此影响，A股市场生物医药股拉升，其中，南模生物、赛伦生物涨超14%，天坛生物10CM涨停，之 江生物、沃森生物、仁度生物、安旭生物等跟涨。 ...

Group 1 - The A-share market saw a surge in biopharmaceutical stocks, with notable increases including Nanmo Bio and Sairun Bio rising over 14%, and Tiantan Bio hitting a 10% limit up [1] - The China CDC and other teams completed the first Phase I clinical trial of a replicative Tian Tan smallpox vaccine-based HIV vaccine, marking a significant advancement in HIV vaccine research in China [1] - The innovative approach utilized the "Tian Tan strain" smallpox virus, previously used to eradicate smallpox, to verify the safety and effective immune response of the vaccine [1]

Group 1 - Rendu Biotech's stock price fell by 7.62% to 52.15 yuan, with a total market value of 2.09 billion yuan, currently in a state of breaking issue [1] - The company was listed on the Shanghai Stock Exchange's Sci-Tech Innovation Board on March 30, 2022, with an initial offering price of 72.65 yuan per share [1] - Rendu Biotech raised a total of 726.5 million yuan, with a net amount of 652.76 million yuan after deducting issuance costs, which was 47.75 million yuan less than originally planned [1] Group 2 - The controlling shareholder and actual controller of Rendu Biotech is Ju Jinliang, who has held various positions in notable companies and has been the chairman and chief scientist since 2007 [2]

证券之星消息，7月29日医疗器械板块较上一交易日下跌0.04%，仁度生物领跌。当日上证指数报收于 3609.71，上涨0.33%。深证成指报收于11289.41，上涨0.64%。医疗器械板块个股涨跌见下表： | 代码 | 名称 | 收盘价 | 涨跌幅 | 成交量(手) | 成交额(元) | | | --- | --- | --- | --- | --- | --- | --- | | 300171 | 东富龙 | 15.17 | 7.82% | 34.04万 | | 5.08亿 | | 688108 | 赛诺医疗 | 13.94 | 3.64% | 24.74万 | | 3.45亿 | | 688114 | 华大智造 | 70.08 | 3.27% | 5.20万 | | 3.59亿 | | 301235 | 体康洁净 | 27.66 | 3.21% | 6.02万 | | 1.64亿 | | 688656 | 浩欧博 | 124.82 | 2.86% | 1.81万 | | 2.25 乙 | | 688198 | 佰仁医疗 | 110.34 | 2.79% | 6816.66 | 7415.15万 | | ...

Investment Rating - The report assigns an "Overweight" rating to the pharmaceutical and biotechnology industry, indicating that the industry index is expected to outperform the CSI 300 index by 10% or more over the next six months [2][40]. Core Insights - The pharmaceutical and biotechnology sector saw an overall increase of 1.90% from July 21 to July 25, 2025, ranking 19th among 31 industries in the Shenwan index, outperforming the CSI 300 index by 0.21 percentage points [4][12]. - The current PE valuation of the pharmaceutical and biotechnology sector is 30.67 times, which is at the historical median level, with a valuation premium of 140% compared to the CSI 300 index [4][18]. - The top three performing sub-sectors during the same period were medical services (6.73%), medical devices (4.43%), and pharmaceutical commerce (1.84%) [4][12]. Market Performance - In the year-to-date, the pharmaceutical and biotechnology sector has increased by 18.81%, ranking 3rd among 31 industries, and outperforming the CSI 300 index by 13.92 percentage points [4][13]. - The sub-sectors that achieved significant gains include chemical pharmaceuticals (34.25%), medical services (32.34%), and biological products (13.49%) [4][19]. Industry News - The National Healthcare Security Administration (NHSA) held two meetings to support the high-quality development of innovative drugs and medical devices, emphasizing the need for comprehensive value assessments for innovative products [5][34]. - The NHSA introduced new measures to empower innovation in drug and device pricing, aiming to support genuine innovation and improve the quality of healthcare in China [5][36]. Investment Recommendations - The report suggests focusing on high-quality stocks in the following segments: innovative drugs, CXO (Contract Research Organization), chain pharmacies, medical services, and second-class vaccines [5][37][38]. - Recommended stocks include Betta Pharmaceuticals, Teva Biopharmaceuticals, Kaili Medical, Haier Biomedical, Huaxia Eye Hospital, and Lao Bai Xing [5][38]. Stock Performance - During the last week, 337 stocks in the sector increased in value (71.10%), while 127 stocks decreased (26.79%). The top five gainers were Haitai Biological (46.93%), Zhendong Pharmaceutical (42.89%), Saili Medical (31.73%), Chenxin Pharmaceutical (30.75%), and Rendu Biological (27.82%) [4][27].

Core Viewpoint - The article highlights the urgent need for effective detection and control measures against mosquito-borne diseases, particularly Chikungunya virus, as the World Health Organization warns of its spread across 119 countries, affecting approximately 5.5 million people [1]. Group 1: Industry Response - Wanfu Biotech has developed rapid and precise detection solutions for mosquito-borne diseases, providing reliable monitoring schemes for disease prevention and control centers [2]. - Fosun Diagnostics has quickly provided Chikungunya virus test kits to aid in epidemic prevention, emphasizing early detection and treatment as crucial to controlling the spread [7]. - Multiple companies, including BGI and Dean Diagnostics, are leveraging advanced sequencing technologies to enhance the detection capabilities for mosquito-borne viruses, ensuring a comprehensive response to the epidemic [14][19]. Group 2: Detection Technologies - Molecular POCT technology allows for results in just 25 minutes, utilizing magnetic bead-based nucleic acid extraction and real-time fluorescent quantitative PCR to detect pathogens in human serum and plasma [3]. - Various nucleic acid detection kits are available, including those for Chikungunya virus, Dengue virus, and Zika virus, with detection limits as low as 200 copies/mL [6][10]. - RenDu Biotech has introduced a series of detection kits based on real-time fluorescent isothermal amplification technology, which can provide results in 40 minutes, significantly faster than traditional methods [30][31]. Group 3: Product Offerings - Companies are offering a range of test kits for various mosquito-borne pathogens, including those that can detect multiple viruses simultaneously, such as Dengue, Chikungunya, and Zika [11][28]. - The kits are designed for ease of use, with many requiring only standard PCR equipment, thus facilitating widespread adoption in healthcare settings [30]. - High-sensitivity and specificity are emphasized across products, ensuring accurate detection without cross-reactivity with other pathogens [9][8].

Group 1: Overview of Chikungunya Fever - Chikungunya virus is spreading globally, with 119 countries reporting cases and approximately 5.5 million people at risk of infection [1] - In Foshan, Guangdong Province, over 4,000 confirmed cases have been reported, primarily mild cases [1] Group 2: Symptoms and Treatment - Chikungunya fever is characterized by high fever and severe joint pain, particularly affecting small joints [2] - There is currently no specific treatment or widely used vaccine; management is primarily supportive, focusing on symptom relief [3] Group 3: Market Response and Company Involvement - Investors are inquiring about companies with products related to Chikungunya fever, focusing on mosquito repellent products, testing kits, and antipyretic and analgesic medications [4] - Companies like Rainbow Group, Runben Co., and Weigao Medical have reported an increase in sales of mosquito repellent products [5][6] - Pharmaceutical companies such as Renhe Pharmaceutical and Xinhua Pharmaceutical have indicated they offer products for fever and pain relief [7] Group 4: Testing Products - Companies like Kehua Bio, YHLO Biotech, and Shuoshi Bio have developed testing kits for Chikungunya virus [8] - YHLO Biotech has a rapid screening kit for Chikungunya, currently used for research purposes [8] - The market interest in these companies has led to notable stock price increases since the news of the outbreak [8]

Group 1 - The World Health Organization (WHO) reports that 119 countries and regions have identified the spread of Chikungunya virus, with approximately 5.5 million people at risk, potentially leading to widespread outbreaks that could strain health systems [1] - Several A-share listed companies have made strategic moves in response to the Chikungunya virus, including Ayhuilong, Shuoshi Biology, Aotai Biology, Rendu Biology, and Rainbow Group, who have shared their plans on the stock exchange interaction platform [1] Group 2 - Chikungunya fever is primarily transmitted by Aedes mosquitoes, with symptoms including fever, rash, and joint pain. Measures such as eliminating breeding sites and insect extermination can help interrupt transmission [2] - The Guangdong Province reported a local outbreak of Chikungunya fever linked to imported cases, with 3,645 confirmed cases reported as of July 23, all mild, and 2,018 patients have recovered [2] - The National Disease Control Bureau and the Guangdong Provincial Health Commission have dispatched expert teams to guide and participate in epidemic prevention efforts, focusing on cutting community transmission and preventing the spread of the outbreak [2] Group 3 - Multiple A-share listed companies are developing testing solutions for Chikungunya virus, primarily for research purposes or overseas markets. Ayhuilong's partner company has developed a rapid screening kit, while Shuoshi Biology and Aotai Biology also have testing kits available for research use [3] - Currently, there are no approved Chikungunya testing kits in the domestic market, but the approval process for related testing products is expected to accelerate [3] - Rainbow Group offers a wide range of household insecticide products aimed at mosquito control, including electric mosquito repellent and aerosol insecticides, which utilize high-quality active ingredients recommended by WHO [3]