| APA 212"s within children il box 11, 2017 | | | | | | | | | --- | --- | --- | --- | --- | --- | --- | --- | | 交易日期 | 证券简称 | 证券代码 | 成交价(元) 成交金额(万元) 成交量( *) 买入营业部 | | | 奥出营业部 | 是否为专场 | | 025-10-22 | 特宝生物 | 688278 | 77.31 1799.78 | 23.28 | 親愛護護 | 至勞屋交通常業務 | KO | 10月22日，特宝生物大宗交易成交23.28万股，成交额1799.78万元，占当日总成交额的11.7%，成交价 77.31元，较市场收盘价77.31元持平。 ...

Market Overview - The biopharmaceutical sector experienced a decline of 0.57% on October 22, with Aopumai leading the drop [1] - The Shanghai Composite Index closed at 3913.76, down 0.07%, while the Shenzhen Component Index closed at 12996.61, down 0.62% [1] Stock Performance - Notable gainers in the biopharmaceutical sector included: - Wendi Pharmaceutical (688488) with a closing price of 14.77, up 4.01% [1] - Dongbao Bio (300239) at 5.78, up 2.66% [1] - Jinke (688670) at 17.03, up 2.59% [1] - Major decliners included: - Aopumai (688293) at 55.19, down 4.40% [2] - Wofu Bio (300357) at 31.63, down 3.18% [2] - Sanofi (688336) at 59.60, down 2.39% [2] Capital Flow - The biopharmaceutical sector saw a net outflow of 192 million yuan from institutional investors, while retail investors contributed a net inflow of 53.82 million yuan [2] - Specific stock capital flows included: - Te Bao Bio (688278) with a net inflow of 19.00 million yuan from institutional investors [3] - Hualan Bio (002007) with a net inflow of 12.05 million yuan from institutional investors [3] - Aopumai (688293) with a net outflow of 4.40% from institutional investors [3]

资料显示，厦门特宝生物工程股份有限公司位于福建省厦门市海沧新阳工业区翁角路330号，成立日期 1996年8月7日，上市日期2020年1月17日，公司主营业务涉及从事重组蛋白质及其长效修饰药物研发、 生产及销售。主营业务收入构成为：抗病毒用药86.85%，血液/肿瘤用药12.87%，其他(补充)0.27%。 特宝生物所属申万行业为：医药生物-生物制品-其他生物制品。所属概念板块包括：抗癌药物、生物医 药、创新药、肝炎治疗、价值成长等。 截至6月30日，特宝生物股东户数8439.00，较上期增加13.00%；人均流通股48204股，较上期减少 11.51%。2025年1月-6月，特宝生物实现营业收入15.11亿元，同比增长26.96%；归母净利润4.28亿元， 同比增长40.60%。 10月22日，特宝生物盘中下跌2.02%，截至13:09，报76.96元/股，成交7940.44万元，换手率0.25%，总 市值313.07亿元。 资金流向方面，主力资金净流入882.60万元，特大单买入300.99万元，占比3.79%，卖出185.57万元，占 比2.34%；大单买入1843.30万元，占比23.21%，卖出107 ...

Investment Rating - The report maintains a positive outlook on the innovative drug and medical device industry, highlighting key targets for investment [5][24]. Core Insights - The innovative drug sector is experiencing high growth, with a focus on companies such as Jiangsu Heng Rui Medicine, Hansoh Pharmaceutical Group, and others. The report emphasizes the potential for value re-evaluation in these firms [5][24]. - Recent business development (BD) deals in the innovative drug sector are expected to catalyze market activity, with notable transactions including Jiangsu Heng Rui Medicine's agreement with Kite for a $1.20 billion upfront payment, potentially reaching $15.20 billion in total [5][24]. - The A-share pharmaceutical sector underperformed the broader market in the third week of October 2025, with the Shanghai Composite Index falling by 1.5% and the SW Biopharma index declining by 2.5% [7][18]. Summary by Sections 1. Continuous Focus on Innovative Drugs and Medical Devices - The report emphasizes the high growth potential in innovative drugs, with key investment targets including Jiangsu Heng Rui Medicine, Hansoh Pharmaceutical Group, and others. Related targets include CSPC Innovation Pharmaceutical [5][24]. 2. A-Share Pharmaceutical Sector Performance - In the third week of October 2025, the A-share pharmaceutical sector saw a decline of 2.5%, underperforming the Shanghai Composite Index, which fell by 1.5%. The report notes that the sector's premium relative to all A-shares is currently at a normal level, with a relative premium rate of 74.5% [7][14][21]. 3. Hong Kong and U.S. Pharmaceutical Sector Performance - The report indicates that the Hong Kong and U.S. pharmaceutical sectors also underperformed, with the Hang Seng Healthcare index dropping by 5.8% and the S&P 500 Healthcare index increasing by only 0.7% during the same period [18][24].

海沧区厦门生物医药港，30年前还是一片甘蔗地。如今，在这片规划面积6.58平方公里的土地上，上演着中国生物医药产业的创新奇迹：培育出特宝生物等细分领域龙头企业，书写了一部从"政 近日，上海证券报记者走进特宝生物，听其创始人、董事长孙黎讲述特宝生物向未来开放，在创新中不迷失的故事。 解决"人有我无"问题 成立于1996年的特宝生物，主要从事重组蛋白质及其长效修饰药物研发、生产及销售，以免疫相关细胞因子药物研发为核心，致力于为肝病、肿瘤、代谢性相关疾病等治疗领域提供更优解决方 "早期工作解决的是'西方有，我们没有'的问题。20世纪90年代中期，进口药品价格极高。当时一克黄金才100元左右，而一支国外进口的可用于化疗和放疗过程中升白辅助治疗的特尔立同类药 三十载耕耘守初心。目前，特宝生物已构建起以聚乙二醇长效化药物为核心的创新平台技术，已上市包括派格宾、益佩生、珮金等多款聚乙二醇长效化国家1类新药。 数据显示，2018至2024年，特宝生物经营业绩每年均保持增长，营业收入从4.48亿元增加至28.17亿元，净利润从1600万元增加至8.27亿元。 研发过程"九死一生" 特宝生物的成长史，是厦门改革开放实践的一个缩影 ...

Investment Rating - The report indicates a current overall valuation of the pharmaceutical sector at 30.1 times earnings, ranking it 10th among 31 primary sectors in the market [5][8]. Core Insights - The pharmaceutical sector experienced a decline of 2.5% this week, underperforming compared to the Shanghai Composite Index, which fell by 1.5% [3][5]. - The report highlights significant corporate activities, including BMS's acquisition of Orbital Therapeutics for $1.5 billion, which includes a promising CAR-T therapy candidate and proprietary RNA platform technology [4][13]. - The report emphasizes the importance of the 2025 ESMO conference, where multiple Chinese pharmaceutical companies are expected to present clinical data, suggesting a focus on innovative drug sectors and companies with improving performance in medical devices and upstream sectors [4][19]. Market Performance Summary - The pharmaceutical sector's performance this week ranked 16th among 31 sub-industries, with various segments showing mixed results: - Raw materials (-2.3%) - Chemical preparations (-1.7%) - Traditional Chinese medicine (+0.4%) - Medical devices (-5.4%) [3][8]. - The report notes that the pharmaceutical sector's index has seen a decline of 2.5%, while the overall market (excluding financials and oil) dropped by 4.2% [3][5]. Key Events Recap - BMS's acquisition of Orbital Therapeutics is a notable event, as it aims to enhance its capabilities in CAR-T therapies [4][13]. - The approval of new indications for Pegasys by Teva Biopharma is expected to strengthen its market position in hepatitis treatment [4][15]. - Mindray Medical announced plans to issue H shares and list on the Hong Kong Stock Exchange to support its international strategy [4][15]. Clinical Data Highlights - The report includes a summary of clinical data presented at the 2025 ESMO conference, showcasing various drugs and their efficacy in treating different cancers, which may present investment opportunities [19][22].

Investment Rating - The report indicates a current investment rating for the pharmaceutical sector, with the overall valuation at 30.1 times earnings, ranking 10th among 31 primary industries [3][5]. Core Insights - The report highlights a decline of 2.5% in the Shenwan Pharmaceutical and Biological Index, which underperformed compared to the Shanghai Composite Index's decline of 1.5% and the overall A-share market's decline of 4.2% [3][5]. - Key events include BMS's acquisition of Orbital Therapeutics for $1.5 billion, which includes a candidate drug for CAR-T therapy and proprietary RNA platform technology [4][13]. - The report emphasizes the importance of the 2025 ESMO conference, where multiple Chinese pharmaceutical companies are expected to present clinical data, suggesting a focus on innovative drug sectors and companies with improving performance in medical devices and upstream sectors [4][18]. Market Performance Summary - The Shenwan Pharmaceutical and Biological Index fell by 2.5%, ranking 16th among 31 Shenwan primary sub-industries [3][5]. - The performance of various sub-sectors includes: - Raw materials (-2.3%) - Chemical preparations (-1.7%) - Traditional Chinese medicine (+0.4%) - Blood products (-1.6%) - Vaccines (-3.3%) - Other biological products (-3.6%) - Medical equipment (-5.4%) - Medical consumables (-1.7%) - In vitro diagnostics (-0.4%) - Pharmaceutical distribution (-1.5%) - Offline pharmacies (+0.6%) - Medical R&D outsourcing (-6.5%) - Hospitals (-1.5%) [3][8][5]. Key Events Review - BMS's acquisition of Orbital Therapeutics includes a candidate drug for CAR-T therapy and advanced RNA technology [4][13]. - The approval of a new indication for Peginterferon by Teva Biopharma enhances its market competitiveness in hepatitis B treatment [4][14]. - Mindray Medical announced plans to issue H shares and list on the Hong Kong Stock Exchange to support its international strategy [4][15]. - The report suggests monitoring companies presenting at the 2025 ESMO conference, particularly those in the innovative drug sector and those with improving performance metrics [4][18].

10月17日，特宝生物跌1.52%，截至发稿，报77.65元/股，成交1.19亿元，换手率0.37%，总市值315.88 亿元。特宝生物股价已经连续4天下跌，区间累计跌幅7.44%。 风险提示：市场有风险，投资需谨慎。本文为AI大模型自动发布，任何在本文出现的信息（包括但不 限于个股、评论、预测、图表、指标、理论、任何形式的表述等）均只作为参考，不构成个人投资建 议。 资料显示，厦门特宝生物工程股份有限公司位于福建省厦门市海沧新阳工业区翁角路330号，成立日期 1996年8月7日，上市日期2020年1月17日，公司主营业务涉及从事重组蛋白质及其长效修饰药物研发、 生产及销售。主营业务收入构成为：抗病毒用药86.85%，血液/肿瘤用药12.87%，其他(补充)0.27%。 责任编辑：小浪快报 从基金十大重仓股角度 华泰柏瑞量化创盈混合A（010303）基金经理为笪篁。 截至发稿，笪篁累计任职时间5年161天，现任基金资产总规模13.15亿元，任职期间最佳基金回报 62.41%， 任职期间最差基金回报-1.1%。 数据显示，华泰柏瑞基金旗下1只基金重仓特宝生物。华泰柏瑞量化创盈混合A（010303）二季度持有 股 ...

Core Viewpoint - The stock of TEBIO experienced a decline of 2.06% on October 16, 2023, with a trading volume of 1.40 billion yuan and a market capitalization of 31.974 billion yuan [1] Financial Performance - For the first half of 2025, TEBIO reported a revenue of 1.511 billion yuan, representing a year-on-year growth of 26.96%, and a net profit attributable to shareholders of 428 million yuan, which is a 40.60% increase compared to the previous year [2] Shareholder and Market Activity - As of June 30, 2025, TEBIO had 8,439 shareholders, an increase of 13.00% from the previous period, with an average of 48,204 circulating shares per shareholder, down by 11.51% [2] - The stock's performance shows an 8.04% increase year-to-date, but a decline of 3.44% over the last five trading days and 3.99% over the last twenty days [1] Dividend Distribution - TEBIO has distributed a total of 577 million yuan in dividends since its A-share listing, with 506 million yuan distributed over the last three years [3] Institutional Holdings - As of June 30, 2025, the top ten circulating shareholders included the Huaxia SSE STAR 50 ETF, which increased its holdings by 837,500 shares, and the E Fund SSE STAR 50 ETF, which added 189,900 shares [3]

Core Viewpoint - The innovation drug sector in China is experiencing significant growth, driven by increased investment, favorable policies, and a strong pipeline of new drugs entering clinical trials, positioning it for a robust future in both domestic and international markets [6][8][10]. Group 1: Market Performance - As of October 16, the Science and Technology Innovation Drug ETF (Huitianfu, 589120) saw a notable increase of 3.31%, maintaining a rise of over 2% despite a slight pullback [1]. - The ETF has attracted over 40 million yuan in net inflows over the past five days, indicating strong investor interest [1]. - Key constituent stocks such as Sangfor Technology and Yifang Bio have shown significant gains, with Sangfor hitting the daily limit up and Yifang Bio rising by 8.61% [2][3]. Group 2: Industry Trends - The number of License-out transactions in China reached 72 in the first half of 2025, surpassing half of the total for 2024, with a total transaction value 16% higher than the previous year [5]. - The innovation drug sector is primarily driven by business development (BD) expectations, with a significant portion of annual BD activity occurring in the fourth quarter [6]. - The Chinese innovation drug market is expected to see a recovery in confidence as more BD deals materialize, particularly as companies prepare for the upcoming European Society for Medical Oncology (ESMO) conference [6][7]. Group 3: R&D and Financial Outlook - Since 2015, Chinese innovation drug companies have significantly increased R&D investments, leading to a rise in the number of original innovative drugs entering clinical trials, with 704 drugs expected to enter Phase I trials in 2024 [8]. - The revenue of innovation drug companies has been steadily increasing, with projections indicating that one-third of these companies will achieve profitability by 2025, and 70% will reach breakeven by 2026 [8]. - The Chinese government's support for innovation drugs through favorable policies and increased funding is expected to enhance the sector's growth, with healthcare spending on innovation drugs projected to rise from 50 billion yuan in 2022 to 120 billion yuan in 2024 [9]. Group 4: Competitive Landscape - The impending patent cliff for multinational corporations (MNCs) is expected to create a demand for new products, with 190 drugs losing patent protection by 2030, including 69 with annual sales exceeding 1 billion dollars [10]. - Chinese innovation drug companies are well-positioned to fill this gap due to their high R&D efficiency and rich technological outcomes, making them attractive partners for MNCs [10].