礼来此前公布的财报显示，2025年第四季度营收攀升至193亿美元，好于市场预期的179.6亿美元；每股 收益为7.54美元，好于市场预期的6.67美元。在第四季度，Zepbound销售额达43亿美元，高于市场预期 的38亿美元;Mounjaro销售额达74亿美元，同样高于市场预期的67亿美元。 此外，据礼来心血管代谢健康业务负责人肯·卡斯特（Ken Custer）在财报电话会议上表示，公司预计将 在第二季度于美国推出orforglipron，大多数国际市场则将在2027年跟进。 智通财经APP获悉，高盛近日重申对礼来（LLY.US) "买入"评级，并将对该股的目标价从1145美元上调 至1260美元。高盛表示，礼来给出的2026年业绩指引显示出约25%的营收同比增长，并反映出在定价压 力逐渐加大的背景下，市场对肥胖症药物领域的信心依然持续。高盛指出，市场关注点很可能将转向礼 来计划于2026年第二季度推出的口服肥胖症药物orforglipron。礼来管理层表示，该产品对现有注射剂疗 法的替代效应应当有限，且早期迹象支持GLP-1整体市场的进一步扩张。 与此同时，礼来还公布了对2026年的乐观增长展望，增长动力 ...

高盛相信，信达生物将继续保持其在中国生物技术领域的领先地位，主要得益于拥有大量针对下一代免 疫肿瘤靶点的新型分子，并已获得令人鼓舞的初步数据(如IBI363(PD-1/IL-2α偏向性双特异性抗体)，在 免疫治疗/冷肿瘤中具有差异化的药物特性；强大的商业化能力及与全球合作伙伴，特别是礼来公司的 深度合作等。 智通财经APP获悉，高盛发布研报称，信达生物(01801)昨日(8日)宣布与礼来(LLY.US)美元的里程碑付 款；及基于中国以外地区净销售额的分级销售特许权使用费。高盛考虑到当前市场隐含的加权平均资本 成本(12%)较高，认为其目前股价被低估；予该股"买入"评级；基于风险调整后、现金流量折现法，予 目标价102.85港元。 ...

Chinese drugmaker Innovent Biologics and Eli Lilly plan to target cancer and immune system diseases under the partnership. ...

Investment Rating - The report maintains a positive outlook on the pharmaceutical industry, indicating an "Overweight" rating, suggesting that the industry is expected to outperform the overall market [2][33]. Core Insights - The pharmaceutical sector saw a slight increase of 0.14% in the week, while the Shanghai Composite Index decreased by 1.27% [3][2]. - The report highlights the implementation of the "Traditional Chinese Medicine Industry High-Quality Development Implementation Plan (2026-2030)" by the Ministry of Industry and Information Technology and other departments, aiming to enhance the supply chain and technological advancements in the traditional Chinese medicine sector [11][12]. - Key pharmaceutical products such as Eli Lilly's Tirzepatide are projected to generate significant sales, with estimates of $36.5 billion in 2025, reflecting a 99% year-on-year growth for the diabetes version and a 175% growth for the weight loss version [15][17]. - The report notes active licensing and collaboration in the industry, with significant deals such as a $1.5 billion agreement between Saint's RNAi therapy and Genentech, and various other collaborations involving companies like Jichuan Pharmaceutical and Baiyunguan [18][20]. Market Performance Summary - The overall valuation of the pharmaceutical sector is reported at 29.6 times earnings, ranking 13th among 31 sectors [4][14]. - The performance of various sub-sectors includes: - Raw materials (+0.6%) - Traditional Chinese Medicine (+2.6%) - Chemical preparations (-0.8%) - Medical devices (+0.1%) [4][3]. Key Events and Developments - The report emphasizes the importance of the new plan for traditional Chinese medicine, which includes goals such as establishing 60 high-standard raw material production bases and developing 10 major traditional Chinese medicine products by 2030 [12][11]. - Notable company developments include: - Eli Lilly's projected revenue growth driven by Tirzepatide [15]. - And the announcement of significant profit forecasts from Heptares Pharmaceuticals, indicating a shift towards profitability [16]. Investment Recommendations - The report suggests focusing on domestic companies related to traditional Chinese medicine, such as Zoli Pharmaceutical and Yunnan Baiyao, as well as innovative drug companies like Heng Rui Pharmaceutical and Bai Jie Shen Zhou [2][18].

根据合作协议，双方将发挥互补优势，加快推进创新药物的全球研发工作。信达生物依托自身成熟的抗 体技术平台及高效的临床能力，将主导相关项目从药物发现至中国临床概念验证（二期临床试验完成） 的研发工作。根据协议，礼来获得相关项目在大中华区以外的全球独家开发与商业化许可，信达生物保 留相关项目在大中华区的全部权利。 根据协议条款，信达生物将获得3.5亿美元首付款；在达成后续特定里程碑事件后，信达生物还有资格 获得总额最高约85亿美元的研发、监管及商业化里程碑付款。此外，信达生物有权就各产品在大中华区 以外的净销售额获得梯度的销售分成。 近日，信达生物制药集团宣布与礼来制药达成战略合作，携手推进肿瘤及免疫领域创新药物的全球研 发。本次协议为双方第七次合作，进一步深化了双方长期且富有成效的合作伙伴关系，携手为全球患者 带来创新药物。 ...

这一独特的合作架构也为信达生物打造了全新的合作模式，加速公司创新研发管线的全球化开发进程。 根据合 【信达生物】更新：与礼来达成全球战略合作，驱动创新加速与价值兑现 事件：2026年2月8日，信达生物宣布与礼来制药达成战略合作，携手推进肿瘤及免疫领域创新药物的全球研发。 本次协议为双方第七次合作，进一步深化了双方长期且富有成效的合作伙伴关系，携手为全球患者带来创新药 物。 【信达生物】更新：与礼来达成全球战略合作，驱动创新加速与价值兑现 事件：2026年2月8日，信达生物宣布与礼来制药达成战略合作，携手推进肿瘤及免疫领域创新药物的全球研发。 本次协议为双方第七次合作，进一步深化了双方长期且富有成效的合作伙伴关系，携手为全球患者带来创新药 物。 合作看点2：信达生物的核心竞争力在于成熟的抗体技术平台和高效的临床研发能力，在本次合作中被反复强调， 作为主导早期研发的基础。 1）抗体技术平台：成熟的全人抗体发现平台，支持单抗、双抗、三抗、ADC、融合蛋白等。 这一独特的合作架构也为信达生物打造了全新的合作模式，加速公司创新研发管线的全球化开发进程。 根据合作协议，双方将发挥互补优势，加快推进创新药物的全球研发工作。 ...

Core Insights - Innovent Biologics has entered into a partnership with Eli Lilly to develop drugs in the fields of immunology and oncology, with an initial payment of $350 million and potential additional payments of up to $8.5 billion [1] Company Summary - The deal signifies a strategic collaboration between Innovent Biologics and Eli Lilly, focusing on the development of innovative therapies in immunology and oncology [1] - The upfront payment of $350 million indicates a strong commitment from Eli Lilly towards the partnership [1] - The total potential value of the deal, reaching up to $8.5 billion, highlights the anticipated significance and potential success of the drug development efforts [1] Industry Summary - The collaboration reflects ongoing trends in the pharmaceutical industry, where partnerships are increasingly common for drug development, particularly in high-demand areas like immunology and oncology [1] - The financial structure of the deal, with substantial upfront and milestone payments, underscores the competitive landscape and the high stakes involved in developing new therapies [1]

2月8日，信达生物宣布与礼来制药达成战略合作，共同推进肿瘤及免疫领域创新药物的全球研发。根据 合作协议，信达生物将主导相关项目从药物发现至中国临床概念验证（二期临床试验完成）的研发工 作。礼来获得相关项目在大中华区以外的全球独家开发与商业化许可，信达生物保留相关项目在大中华 区的全部权利。根据协议条款，信达生物将获得3.5亿美元首付款；在达成后续特定里程碑事件后，信 达生物还有资格获得总额最高约85亿美元的研发、监管及商业化里程碑付款。此外，信达生物有权就各 产品在大中华区以外的净销售额获得梯度的销售分成。 ...

Group 1 - Eli Lilly and Company (NYSE:LLY) is recognized as a top stock in the healthcare sector by Jim Cramer, praised for its weight loss drug, manufacturing capacity, and drug pipeline [2] - The company's shares have increased by 20% over the past year but have decreased by 2% year-to-date [2] - Goldman Sachs raised its price target for Eli Lilly to $1,260 from $1,145, maintaining a Buy rating, while JPMorgan increased its target to $1,300 from $1,150, keeping an Overweight rating [2] Group 2 - JPMorgan's positive outlook for Eli Lilly followed the company's fourth quarter earnings, highlighting its growth potential in the diabetes and obesity markets [2] - Jim Cramer referred to Eli Lilly as "the Great Drug Company on Earth," emphasizing its significant position in the pharmaceutical industry [3]

Core Insights - The weight loss drug market is shifting focus from injectables to pills, with Eli Lilly performing exceptionally well, showing a 10% increase in stock value and strong sales growth [1][3] - Novo Nordisk's stock has declined following disappointing earnings, with sales growth down by 5% to 13%, equating to a $1.5 billion shortfall compared to expectations [4][10] - Eli Lilly is gaining market share and has a robust pipeline for future drugs, while Novo Nordisk is facing challenges, including a new CEO and cost-cutting measures [8][10] Company Performance - Eli Lilly's sales margins are reported at 40%, indicating strong profitability and market positioning [3] - Novo Nordisk's earnings have decreased, leading to a significant divergence in stock performance compared to Eli Lilly [4][10] - Eli Lilly's stock is trading at higher valuation multiples, with 26-27 times earnings compared to Novo's 13 times, suggesting a premium for Eli Lilly's growth prospects [10] Market Dynamics - The competition in the GLP-1 market is increasing, leading to price reductions and impacting margins for companies like Novo Nordisk [7] - The need for ongoing treatment with GLP-1 drugs is becoming apparent, as many patients require continuous use to maintain weight loss [6] - The overall market is experiencing volatility, with concerns about potential declines in major tech stocks affecting investor sentiment [14][16]