Verve Therapeutics(VERV)

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Lilly completes acquisition of Verve Therapeutics to advance one-time treatments for people with high cardiovascular risk
Prnewswire· 2025-07-25 12:49
Core Insights - Eli Lilly and Company has successfully completed the acquisition of Verve Therapeutics, a clinical-stage company focused on genetic medicines for cardiovascular disease [1] - The acquisition is expected to transform treatment paradigms for millions of patients by providing lifelong cardiovascular risk reduction through a single treatment [2] Company Overview - Eli Lilly has been a pioneer in medical discoveries for nearly 150 years, helping tens of millions globally with its medicines [2] - The company is focused on addressing significant health challenges, including diabetes care, obesity, Alzheimer's disease, immune system disorders, and difficult-to-treat cancers [2] Strategic Implications - The integration of Verve Therapeutics is anticipated to enhance Lilly's capabilities in developing innovative genetic medicines for cardiometabolic diseases [2] - The acquisition aligns with Lilly's mission to make life better for millions by advancing clinical trials and ensuring medicine accessibility [2]
Lilly and Verve announce expiration of Verve tender offer
Prnewswire· 2025-07-24 12:00
Core Viewpoint - Eli Lilly and Verve Therapeutics have completed a tender offer for Verve's common stock, with a purchase price of $10.50 per share and a contingent value right potentially worth up to $3.00 per share, which expired on July 23, 2025 [1][2]. Group 1: Acquisition Details - The tender offer resulted in 49,882,464 shares being validly tendered, representing approximately 55.7% of the outstanding shares [2]. - All conditions for the acquisition have been satisfied, and Lilly will proceed to pay for the validly tendered shares [2]. - The acquisition is expected to be finalized on July 25, 2025, in accordance with the definitive agreement [3]. Group 2: Company Profiles - Verve Therapeutics is a clinical-stage company focused on developing genetic medicines for cardiovascular diseases, with lead programs targeting key drivers of atherosclerosis [4]. - Lilly is a long-established pharmaceutical company dedicated to advancing healthcare solutions across various significant health challenges, including diabetes, obesity, Alzheimer's disease, and cancer [5].
3 Bullish Biotech Stocks With Explosive Growth Trends
MarketBeat· 2025-07-21 15:03
Core Insights - Investing in biotechnology stocks involves long periods of inactivity followed by sharp movements, particularly in small-cap biotech stocks which often lack profitability and revenue [1][2] Group 1: Urogen Pharma - UroGen Pharma is focused on treating urologic cancers with its proprietary RTGel technology, enhancing drug efficacy by prolonging retention in the urinary tract [4] - UroGen stock has increased approximately 43% in 2025 due to an application to expand the Jelymyto label for low-grade bladder cancer, potentially increasing its market [5] - Analyst forecasts suggest a price target of $32.86 for URGN stock, indicating a potential gain of over 115% from its closing price on July 18, although short interest is high at over 42% [6] Group 2: Nektar Therapeutics - Nektar Therapeutics has seen a 78% gain in 2025 but remains down over 93% in the last five years due to several clinical trial failures [8] - Positive Phase 2b clinical trial results for a candidate treating systemic lupus erythematosus and ulcerative colitis have generated bullish sentiment, along with a Fast Track designation from the FDA [9] - The consensus price target for NKTR stock is $88.33, representing a 254% increase from its closing price on July 18, but a pullback is anticipated due to recent price surges [10] Group 3: Verve Therapeutics - Verve Therapeutics is pioneering gene editing to treat cardiovascular disease, currently in the clinical stage with revenue primarily from partnerships [12] - The company received approval for a Phase 1b U.S. clinical trial for its lead candidate, VERVE-102, targeting the PCSK9 gene associated with high cholesterol [13] - Analysts have set a price target of $14.57 for VERV stock, indicating a 33% upside, although this is lower compared to the other stocks mentioned [13]
礼来超10亿美元押注基因疗法,“心脏疫苗”问世还有多远?
Di Yi Cai Jing· 2025-06-18 04:53
Core Viewpoint - Eli Lilly announced the acquisition of Verve Therapeutics for up to $1.3 billion, including nearly $1 billion upfront payment, which significantly boosted Verve's stock price by over 80% on the announcement day [1][3]. Group 1: Acquisition Details - Eli Lilly's acquisition of Verve Therapeutics aims to enhance its portfolio in the cardiovascular disease treatment sector, alongside its existing GLP-1 weight loss drug, expected to generate over $30 billion in total sales this year [3]. - Verve Therapeutics is developing a gene-editing therapy, Verve-102, targeting the PCSK9 protein to lower cholesterol levels, potentially transforming chronic cardiovascular disease treatment into a one-time therapy [1][3]. Group 2: Market Potential and Clinical Trials - Verve-102 is currently undergoing a Phase 1b clinical trial and has received Fast Track designation from the FDA, indicating its potential for significant market impact if proven effective [3]. - The gene therapy market for cardiovascular diseases may face skepticism regarding demand, as existing PCSK9-targeting drugs already meet a substantial portion of market needs [4]. Group 3: Competitive Landscape - The PCSK9 monoclonal antibodies have shown to reduce LDL cholesterol levels by over 50% compared to statins, with several products already available in the market, including a long-acting PCSK9 monoclonal antibody recently launched in China [4][5]. - Oral PCSK9 inhibitors from major pharmaceutical companies like Merck and AstraZeneca are expected to drive sales from approximately $4 billion to $12 billion by 2034, indicating a growing competitive landscape [6].
异动盘点0618|乐华娱乐涨超24%,旗下潮玩创销售纪录;顺丰同城涨超5%;脑再生科技续涨超 30%; 比特币概念股普跌
贝塔投资智库· 2025-06-18 04:17
Group 1: Hong Kong Stocks - Lehua Entertainment (02306) surged over 24% due to strong market performance of its toy IP "WUKUKU," with multiple new products setting sales records and the theme song exceeding 1 billion views [1] - United Energy Group (00467) rose over 7% after signing a 15-year production increase contract with Uzbekistan's UNG, involving 57.8 billion cubic meters of oil and gas production, with an initial investment of $100 million to expand into Central Asia [1] - Smoore International (06969) fell over 3% as shareholder Yiwei Lithium Energy plans to reduce its stake by 3.5% (216 million shares), resulting in a decrease of its holding to 27.23%, no longer being the controlling shareholder [1] - New World Development (00200) dropped over 5% after completing a "2 for 1" rights issue, issuing 758 million shares and raising HKD 771 million, with oversubscription of 13 times [1] - Fourth Paradigm (06682) increased over 7% after launching AI solutions for the manufacturing industry, covering production optimization to supply chain intelligence upgrades [1] - Shandong High-Tech Holdings (00412) rose over 4% as Zhongtai Securities highlighted significant synergy between its new energy and digital infrastructure, with a data center PUE value of 1.15, enhancing financial integration [1] - KANAT Optical (02276) increased over 4% due to an explosion in the smart glasses market (e-commerce transactions up 8 times), with Meta collaborating with Oakley to launch AI glasses, positioning the company with leading 3C enterprises [1] Group 2: Other Notable Stocks - Sipai Health (00314) rose over 7% after partnering with Anruijiaer to develop customized insurance, planning to sell 6 pharmacies for 5.89 million to focus on core medical insurance business [2] - SF Express (09699) increased over 5% after raising its delivery service revenue cap for 2025/26 to HKD 12.8 billion / HKD 20.5 billion, with demand growth exceeding expectations [2] - Liufu Group (00590) fell over 3% as it projected a 40% decline in profits for the 2025 fiscal year, primarily due to gold hedging losses and high base effects from acquisition gains [2] - Zhenjiu Lidu (06979) rose over 4% after announcing Yao Annan as the "Cultural Heritage Ambassador" for liquor, leveraging Huawei-related topics to boost brand visibility [2] - Ideal Auto-W (02015) dropped over 4% as Meituan's Wang Xing sold 5.73 million shares for HKD 600 million, reducing his stake to 20.61% [2] - Health Road (02587) surged over 7% as its liver disease AI management platform was selected for Beijing's digital medical verification program, supporting WHO's "2030 Hepatitis Elimination" goal [2] - Gilead Sciences-B (01672) rose over 5% after its psoriasis oral drug ASC50 completed the first dosing in Phase I clinical trials in the U.S., targeting the IL-17 pathway [2] - China Silver Group (00815) increased over 10% after partnering with Zefeng Gold to acquire a 55% stake in a lead-zinc exploration company, gaining exploration rights over 50.8 square kilometers in Tibet [2] Group 3: U.S. Stocks - Verve Therapeutics (VERV.US) skyrocketed over 80% as Eli Lilly prepares to acquire the gene-editing company for up to $1.3 billion, with $1 billion as an upfront payment and $300 million contingent on specific clinical milestones [4] - Solar energy stocks plummeted, with Sunrun (RUN.US) down over 40%, Solaredge Technologies (SEDG.US) down over 41%, and First Solar (FSLR.US) down over 22%, following a Republican proposal in the U.S. Senate to terminate wind and solar tax credits by 2028, raising concerns about the industry's outlook [4] - Reddit (RDDT.US) rose over 6% after launching the AI advertising tool Reddit Insights, enhancing ad targeting through real-time user trend analysis [4] - Bitcoin-related stocks fell, with CleanSpark (CLSK.US) down over 7% and Riot Platforms (RIOT.US) down over 5%, as Bitcoin prices dropped nearly 2% to $105,580 amid escalating tensions in the Middle East and high leverage positions in the derivatives market [4] - AMD (AMD.US) continued to rise 0.56% after officially launching the Zen5 architecture Ryzen Threadripper processors, covering the workstation and desktop markets, with a market share close to 50% in China for Q1, although there are concerns about its cost-performance ratio [5] - Brain Regen Technologies (RGC.US) surged over 30% after announcing a 38-for-1 stock split, coupled with FDA clinical trial approval news, although its actual business has no revenue and a very small float, indicating significant retail speculation [6] - Jabil (JBL.US) rose over 8%, reaching a new all-time high of $202.5, with Q3 revenue increasing 15% year-on-year to $7.83 billion, raising its full-year revenue forecast to $29 billion and planning a $500 million investment to support AI data center infrastructure [6] - Niu Technologies (NIU.US) increased over 11% after launching its new NX Play electric motorcycle on Douyin, integrating a smart riding system to enhance user experience [6] - T-Mobile US (TMUS.US) fell nearly 4% as SoftBank sold 21.5 million shares at $224 each, a 3% discount, triggering market sell-off [6] - The pharmaceutical sector saw widespread declines, with Eli Lilly (LLY.US) down over 2% and Novo Nordisk (NVO.US) down over 3%, as concerns grew over the potential impact of the U.S. Senate tax bill on the industry, coupled with profit-taking ahead of some companies' earnings reports [6] - The gold sector declined, with Gold Fields (GFI.US) down over 2.1%, and spot gold fell 0.27% to $3,375.53, as easing tensions in the Middle East reduced safe-haven demand, alongside Citigroup's bearish long-term gold price forecast [7]
礼来(LLY.US)收购Verve(VERV.US)带来行业提振 基因编辑板块迎上涨
智通财经网· 2025-06-18 03:35
Core Viewpoint - The acquisition of Verve Therapeutics by Eli Lilly for up to $1.3 billion has positively impacted the biotechnology sector focused on gene therapy, which has faced significant challenges recently [1] Group 1: Acquisition Details - Eli Lilly agreed to acquire Verve Therapeutics for a total price not exceeding $1.3 billion, providing a boost to the struggling gene therapy industry [1] - The acquisition led to a 74% increase in Verve Therapeutics' stock price, reflecting positive market sentiment [1] - The deal includes a contingent value right (CVR) that exceeds Verve's 30-day average stock price by over 100% [1] Group 2: Market Reactions - Companies such as Editas Medicine, Prime Medicine, Intellia Therapeutics, CRISPR Therapeutics, and Beam Therapeutics have shown improved performance following the acquisition news, despite experiencing significant declines over the past 12 months [1] - Wall Street reacted positively to Eli Lilly's acquisition proposal, indicating a favorable outlook for the gene editing sector [1] Group 3: Analyst Opinions - BMO Capital Markets expressed skepticism regarding the market demand for additional gene therapies, suggesting that Eli Lilly might have better uses for its capital [2] - Conversely, William Blair viewed the transaction as beneficial for Verve Therapeutics' shareholders, who will receive payments related to the CVR in the coming years [2] - Analyst Myles Minter stated that the acquisition is reasonable for Verve Therapeutics' shareholders and aligns well with Eli Lilly's product line [2]
突发利好!深夜大涨超70%!
证券时报· 2025-06-17 16:01
Market Overview - The US stock market opened lower on June 17, with the Dow Jones down 0.24%, S&P 500 down 0.29%, and Nasdaq down 0.40% [1][2] - Major tech stocks mostly declined, with Tesla dropping nearly 2% and Microsoft, Apple, Google A, and Meta experiencing slight decreases [2] - The Nasdaq China Golden Dragon Index fell by 0.74% [2] Economic Data - The US Census Bureau reported a 0.9% month-over-month decline in retail sales for May, with April's figure revised to a 0.1% decrease [2] - The US Bureau of Labor Statistics indicated that the import price index remained unchanged, while the export price index decreased by 0.9% [2] Corporate News - Verve Therapeutics saw its stock price surge over 70% following an announcement from Eli Lilly that it would acquire the company for up to $1.3 billion [4][6] - Eli Lilly's acquisition includes a nearly $1 billion upfront payment and up to $300 million contingent on achieving certain clinical milestones [5][6] - Verve is developing gene editing drugs, with its lead project, Verve-102, currently in a Phase 1b clinical trial and has received Fast Track designation from the FDA [6] Sector Performance - Chinese concept stocks mostly declined, with notable drops in Kingsoft Cloud and Li Auto, while JD, Pinduoduo, and Alibaba saw slight increases [3] - Brain-computer interface stocks, particularly Brain ReGen Technologies, experienced significant gains, with a year-to-date increase of over 460 times [6][7] International Developments - Oil prices rose over 2.5%, with energy stocks in the US also seeing gains [8] - The European Commission proposed legislation to phase out imports of Russian natural gas and oil by the end of 2027, aiming to reduce dependency on Russian fossil fuels [9][10]
Why Verve Therapeutics Stock Is Skyrocketing Today
The Motley Fool· 2025-06-17 15:05
Acquisition Details - Eli Lilly has entered into a definitive agreement to acquire Verve Therapeutics for $10.50 per share in cash, representing a premium of approximately 113% over the 30-day volume-weighted average trading price of Verve stock as of June 16, 2025 [1] - Verve shareholders will also receive one nontradable contingent value right (CVR) per share, which could entitle them to an additional $3 per share upon the first patient being dosed with VERVE-102 in a U.S. phase 3 clinical trial, potentially bringing the total purchase price to around $1.3 billion [2] Strategic Rationale - Verve Therapeutics is recognized as a leader in base editing, a precise gene editing technology, with its flagship product VERVE-102 currently in a phase 1b clinical study for treating atherosclerotic cardiovascular disease (ASCVD) [3] - Lilly's interest in Verve is driven by the potential of VERVE-102 to become the first in vivo gene editing therapy for a broad patient population, which could transform the treatment approach for cardiovascular disease from chronic management to a one-time treatment [4] Market Considerations - The contingent value right (CVR) associated with Lilly's acquisition could attract investors who are optimistic about the success of VERVE-102, despite the inherent risks of clinical-stage drug development [6] - While there are risks that VERVE-102 may not progress to phase 3 testing, the current acquisition scenario suggests that it may not be too late for investors to consider purchasing Verve stock [7]
Biotech Stock Surging on Billion-Dollar Buyout
Schaeffers Investment Research· 2025-06-17 13:53
Core Viewpoint - Verve Therapeutics Inc (NASDAQ:VERV) has seen a significant stock increase of 75.3% to $10.99 following the announcement that Eli Lilly (LLY) will acquire the company for $10.50 per share, totaling approximately $1.3 billion, enhancing Eli Lilly's position in gene editing [1]. Group 1 - VERV is trading at its highest level since April 2024, with an 11.2% year-to-date gain, supported by the $6 region and the 100-day moving average, which were previously resistance levels earlier this year [2]. - Short interest in VERV has increased by 7.2%, now representing 23.5% of the total available float, indicating a significant bearish sentiment among investors [3]. - At the current average daily trading pace, it would take shorts nearly six days to cover their positions, suggesting a potential for volatility in the stock [3]. Group 2 - Options trading activity has been notably bullish, with a put/call open interest ratio (SOIR) of 0.10, placing it in the 5th percentile of annual readings, indicating strong bullish sentiment among short-term options traders [3]. - Today's options activity shows 11,000 puts and 7,164 calls traded, which is 267 times the typical volume, highlighting heightened interest in the stock [4]. - The most active options contract is the November 10 put, where new positions are being opened, suggesting strategic positioning by traders [4].
礼来(LLY.US)拟以最高13亿美元收购基因编辑公司Verve Therapeutics(VERV.US)
智通财经网· 2025-06-17 12:38
Core Viewpoint - Eli Lilly (LLY.US) has announced an agreement to acquire Verve Therapeutics (VERV.US) for up to $1.3 billion, indicating a significant investment in gene editing technology aimed at cardiovascular disease treatment [1][2] Group 1: Acquisition Details - Eli Lilly will make a cash offer of $10.50 per share, totaling approximately $1 billion, to acquire all outstanding shares of Verve [1] - Each share will also include a non-tradable contingent value right, allowing holders to receive up to an additional $3, bringing the total potential value per share to $13.50 [1] - The base purchase price represents a premium of about 113% over Verve's 30-day volume-weighted average price as of June 16, 2025 [1] Group 2: Market Reaction - Following the announcement, Verve's stock price surged nearly 80% in pre-market trading [1] Group 3: Product Pipeline - Verve is advancing a series of in vivo gene editing projects aimed at safely inactivating genes that increase the risk of atherosclerotic cardiovascular disease [1] - The candidate drug VERVE-102 is currently in Phase 1b clinical trials targeting patients with heterozygous familial hypercholesterolemia and early-onset coronary artery disease [1] - VERVE-102 has received Fast Track designation from the U.S. Food and Drug Administration [1][2]