Core Viewpoint - Shanghai Pharmaceuticals (601607.SH) has received approval from the National Medical Products Administration for the marketing license of SPH3127 tablets, a new oral non-peptide small molecule renin inhibitor for the treatment of primary hypertension [1] Group 1: Product Approval - The product, SPH3127 tablets (also known as Apixaban), has been granted a drug registration certificate with the approval number H20250067 [1] - The approval signifies a significant milestone for the company in expanding its product portfolio in the hypertension treatment market [1] Group 2: Product Efficacy - SPH3127 tablets directly inhibit renin, counteracting the blood pressure increase caused by the overactivation of the renin-angiotensin-aldosterone system (RAAS) [1] - Preclinical and clinical studies indicate that SPH3127 exhibits stronger renin activity inhibition compared to other drugs targeting the same pathway [1] - Clinical research has demonstrated good overall safety and clear antihypertensive efficacy in patients with primary hypertension, fulfilling a clinical need for new treatment options [1] Group 3: Research and Development Investment - The company has invested approximately 296 million yuan in the research and development of SPH3127 tablets to date [1]

Core Viewpoint - Shanghai Pharmaceuticals has received approval from the National Medical Products Administration for the marketing license of its new drug, SPH3127 tablets, which is a novel oral non-peptide small molecule renin inhibitor for the treatment of primary hypertension [1] Company Summary - The drug, SPH3127 tablets, is designed to directly inhibit renin, counteracting the blood pressure increase caused by the overactivation of the renin-angiotensin-aldosterone system (RAAS) [1] - Clinical studies have demonstrated that SPH3127 tablets exhibit a clear antihypertensive effect in patients with hypertension, indicating good overall safety and efficacy [1] - The total research and development investment for SPH3127 tablets has reached approximately 296 million yuan [1] Industry Summary - SPH3127 tablets represent a new treatment option for patients with primary hypertension, addressing an unmet clinical need in this patient population [1] - The drug has shown stronger renin activity inhibition compared to other drugs targeting the same pathway, as evidenced by both in vitro and in vivo pharmacological studies [1]

Core Viewpoint - Shanghai Pharmaceuticals (601607) announced that its subsidiary, Shanghai Pharmaceuticals Xinyi, received a drug registration certificate from the National Medical Products Administration for the approval of its application for the marketing license of Apixaban Tablets, a new generation of oral non-peptide small molecule renin inhibitors [1] Group 1 - The approved drug, Apixaban Tablets, directly inhibits renin, counteracting the increase in blood pressure caused by the overactivation of the renin-angiotensin-aldosterone system (RAAS) [1] - The drug is indicated for the treatment of primary hypertension [1]

Core Viewpoint - Shanghai Pharmaceuticals (601607.SH) has received approval from the National Medical Products Administration for the marketing license of its new drug, SPH3127 tablets, which is a novel oral non-peptide small molecule renin inhibitor for the treatment of primary hypertension [1] Group 1: Drug Approval and Characteristics - The drug name is SPH3127 tablets, with the application acceptance number CXHS2400037 [1] - SPH3127 is designed to directly inhibit renin, counteracting the blood pressure increase caused by the overactivation of the renin-angiotensin-aldosterone system (RAAS) [1] - Preclinical and clinical studies indicate that SPH3127 exhibits stronger renin activity inhibition compared to other drugs targeting the same pathway, demonstrating efficacy in models of hypertension, chronic kidney disease, and inflammatory bowel disease [1] Group 2: Clinical Efficacy and Safety - Completed clinical studies show that SPH3127 has good overall safety and clear antihypertensive efficacy in patients with hypertension [1] - The drug aims to meet the clinical needs of patients with primary hypertension by providing a new treatment option [1] Group 3: Research and Development Investment - To date, approximately 296 million yuan has been invested in the research and development of SPH3127 [1]

Core Viewpoint - Shanghai Pharmaceuticals has received approval from the National Medical Products Administration for its new drug, SPH3127 tablets, which are indicated for the treatment of primary hypertension [1] Group 1: Company Developments - Shanghai Pharmaceuticals' subsidiary, Shanghai Shiyin Pharmaceutical Factory, has been granted a drug registration certificate for SPH3127 tablets [1] - The drug is a new generation oral non-peptide small molecule renin inhibitor [1] Group 2: Industry Context - SPH3127 tablets work by directly inhibiting renin, counteracting the blood pressure increase caused by the overactivation of the renin-angiotensin-aldosterone system (RAAS) [1] - The drug is specifically designed for the treatment of primary hypertension [1]

Group 1 - The China Securities Central Enterprises Dividend Index (931233.CSI) includes 50 stocks of centrally controlled enterprises with stable dividend levels and high dividend yields, achieving a one-year dividend yield of 6.71% as of December 9, which is higher than the 10-year government bond yield of 4.84% [1] - The Hang Seng High Dividend Yield Index (HSMCHYI.HI) consists of high dividend stocks from mainland companies listed in Hong Kong, with a one-year dividend yield of 6.19% as of December 9, surpassing the 10-year government bond yield of 4.31% [1] - The Non-Standard Poor's Hong Kong Stock Connect Low Volatility Dividend Index (SPAHLVHP.SPI) includes 50 high dividend low volatility stocks listed in Hong Kong, with the Hong Kong Stock Connect Low Volatility Dividend ETF (159118) being the ETF with the lowest comprehensive fee tracking this index [1] Group 2 - Shanghai Pharmaceuticals announced a dividend of HKD 0.13215 per share, with an ex-dividend date of December 30, 2025, and a payment date of February 6, 2026 [1]

证券代码：601607 证券简称：上海医药 公告编号：临2025-113 上海医药集团股份有限公司 2025年第二次临时股东大会决议公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或者重大遗漏，并对其内容 的真实性、准确性和完整性承担法律责任。 重要内容提示： ● 本次会议是否有否决议案：无 一、会议召开和出席情况 (一)股东大会召开的时间：2025年12月9日 ■ (四)表决方式是否符合《公司法》及《公司章程》的规定，大会主持情况等。 2025年第二次临时股东大会（以下简称"本次股东大会"）由本公司董事会召集、董事长杨秋华先生主 持，采用现场与网络投票（网络投票仅针对A股股东）相结合的表决方式，本公司股东代表、监事代表 及律师于股东会上担任监票人。本公司股东会议的召集、召开和表决方式符合《中华人民共和国公司 法》等法律法规和《上海医药集团股份有限公司章程》的有关规定。 (五)公司董事、监事和董事会秘书的出席情况 1、公司在任董事9人，出席5人，董事张文学先生、董明先生，独立董事顾朝阳先生、霍文逊先生因其 他公务未能出席本次股东大会。 (二)股东大会召开的地点：中国上海市黄浦区太仓路2 ...

Group 1 - The company Shanghai Pharmaceuticals (601607)(02607) announced a mid-term dividend distribution of HKD 1.3215 per 10 shares, scheduled for February 6, 2026 [1]

Core Viewpoint - Shanghai Pharmaceuticals (02607) announced a mid-term dividend of HKD 1.3215 per 10 shares, to be distributed on February 6, 2026 [1] Company Summary - The company is set to distribute a mid-term dividend, indicating a commitment to returning value to shareholders [1]

第一章 總則 第一條 為強化董事會決策功能，做到事前審計、專業審計，確保董事會對 總裁層級的有效監督，完善公司治理結構，根據《中華人民共和國公司法》、《上 市公司獨立董事管理辦法》、《上市公司治理準則》、《香港聯合交易所有限公 司證券上市規則》（"《聯交所上市規則》"）、《上海證券交易所股票上市規 則》、《上海證券交易所上市公司自律監管指引第 1 號——規範運作》、《公司 章程》、《董事會議事規則》及其他有關規定，公司特設立董事會審計委員會（"審 計委員會"），並制定本實施細則（"細則"）。 第二條 審計委員會是董事會下設的專門工作機構，主要負責公司與外部審 計機構的關係，審閱公司的財務資料，監管公司財務申報制度、風險管理及內部 監控系統，以及審議監督公司環境、社會及管治事宜。 第二章 人員組成 第三條 審計委員會成員由三名獨立董事組成，其中至少有一名為專業會計 人士。 第四條 審計委員會委員由董事長、二分之一（1/2）以上獨立董事或者全 體董事的三分之一（1/3）以上提名，並由董事會選舉產生。 第五條 審計委員會設召集人一（1）名，由委員中的專業會計人士擔任， 負責主持委員會工作；召集人在委員內選舉，並報請 ...