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MRK's ADC Candidate Gets FDA Breakthrough Therapy Tag for Lung Cancer
ZACKS· 2025-08-19 16:41
Group 1: FDA Breakthrough Therapy Designation - Merck's B7-H3-directed ADC, ifinatamab deruxtecan (I-DXd), received FDA's Breakthrough Therapy designation for treating extensive-stage small cell lung cancer in adults whose disease progressed after platinum-based chemotherapy [1][8] - The Breakthrough Therapy designation accelerates the development and review of drugs for serious conditions when early clinical evidence indicates significant improvement over existing treatments [2] Group 2: Clinical Studies and Data - The FDA's decision was based on data from the phase II IDeate-Lung01 study, which evaluated the safety and efficacy of I-DXd, supported by the phase I/II IDeate-PanTumor01 study [3][8] Group 3: Stock Performance - Year to date, Merck's shares have decreased by 15.3%, while the industry has seen a decline of 2.8% [4] Group 4: Collaboration and Development - Merck acquired global co-development and co-commercialization rights to I-DXd and two other ADCs from Daiichi Sankyo for a potential total consideration of up to $22 billion, although Daiichi retains exclusive rights for development in Japan [6][9] - I-DXd is also being evaluated in phase III studies for esophageal and prostate cancers, and it has an orphan drug designation for small-cell lung cancer in multiple regions [5][8] Group 5: ADC Market Competition - ADCs are viewed as a disruptive innovation in the pharmaceutical industry, enhancing cancer treatment by targeting tumors with cytotoxic drugs [11] - Daiichi Sankyo has multiple ADCs in clinical development and markets Enhertu in partnership with AstraZeneca, which is approved for various cancer indications [12] - Pfizer entered the ADC market by acquiring Seagen for $43 billion, adding several ADCs to its portfolio that have contributed significantly to its revenues [13][14]
PayPal vs. Block: Which Fintech Stock Is the Better Buy Right Now?
ZACKS· 2025-08-19 16:41
Core Insights - PayPal and Block are both key players in the fintech space, each with distinct approaches to digital payments and commerce [1][2] - PayPal focuses on a global two-sided payments platform, while Block operates through its Square and Cash App ecosystems [1] PayPal Overview - PayPal reported a 5% year-over-year revenue increase to $8.3 billion, with Total Payment Volume (TPV) rising 6% and non-GAAP EPS growing 18% to $1.40 [3] - The company raised its full-year EPS and transaction margin dollar guidance, indicating confidence in ongoing momentum [3] - PayPal's growth strategy includes enhancing checkout experiences, expanding Venmo, improving payment services profitability, and investing in AI and stablecoins [4] - Venmo's revenue grew over 20% year over year, with a 40% increase in monthly active accounts for the Venmo Debit Card and a 45% rise in TPV [4] - Despite challenges such as a 5% decline in payment transactions and a 4% drop in engagement per user, PayPal's fundamentals remain strong [5][6] Block Overview - Block's second quarter saw a 2% year-over-year revenue decline to $6.05 billion, but gross profit increased by 14% to $2.54 billion [7] - Cash App contributed significantly with a 16% gross profit increase, while Square saw an 11% rise [7] - Block introduced new features like Cash App Pools and Afterpay integrations, enhancing user engagement [9] - The company faces challenges, including reliance on Bitcoin and competition in consumer payments, which may limit its broader market reach compared to PayPal [11] Comparative Analysis - PayPal offers greater global scale and a stronger branded checkout presence, while Block is more U.S.-centric and focused on younger demographics [10][11] - PayPal's 2025 sales and EPS estimates suggest a year-over-year increase of 3.97% and 12.04%, respectively, with EPS estimates trending upward [12] - In contrast, Block's 2025 sales are expected to rise by 1.83%, but EPS is projected to decline by 23.7%, with estimates trending downward [13] Valuation and Performance - PayPal shares are considered undervalued with a Value Score of A, while Block shares are viewed as overvalued with a Value Score of D [15] - PayPal's forward Price/Sales ratio is 1.94X, below its three-year median, whereas Block's is 1.81X, above its three-year median [16] - Over the past three months, Block's shares have outperformed PayPal and the S&P 500 composite [17] Conclusion - PayPal demonstrates steady, profitable growth and strong global positioning, making it a more attractive investment currently [20] - Block, while innovative and engaging, faces greater volatility and earnings inconsistency, suggesting it remains a hold for long-term potential [20]
LYG or EBKDY: Which Is the Better Value Stock Right Now?
ZACKS· 2025-08-19 16:41
Core Viewpoint - Investors in the Banks - Foreign sector may find Lloyds (LYG) and Erste Group Bank AG (EBKDY) as potential stocks to consider, with a focus on determining which stock is more appealing to value investors [1] Valuation Metrics - Both LYG and EBKDY currently hold a Zacks Rank of 2 (Buy), indicating positive revisions to their earnings estimates and improving earnings outlooks [3] - The Style Score Value grade incorporates various fundamental metrics, including P/E ratio, P/S ratio, earnings yield, and cash flow per share, which are essential for value investors [4] Specific Valuation Comparisons - LYG has a forward P/E ratio of 11.52, while EBKDY has a forward P/E of 11.70; LYG's PEG ratio is 0.70 compared to EBKDY's 0.98, suggesting LYG may be undervalued relative to its expected earnings growth [5] - LYG's P/B ratio stands at 1.09, indicating a favorable market value compared to its book value, while EBKDY's P/B ratio is higher at 1.28; these metrics contribute to LYG's Value grade of B and EBKDY's Value grade of D [6] Investment Recommendation - Based on the valuation figures, LYG is considered the superior value option compared to EBKDY, despite both stocks having solid earnings outlooks [7]
CNA or CINF: Which Is the Better Value Stock Right Now?
ZACKS· 2025-08-19 16:41
Core Viewpoint - Investors are evaluating CNA Financial and Cincinnati Financial to determine which stock presents a better value opportunity for investment [1] Valuation Metrics - Both CNA Financial and Cincinnati Financial currently hold a Zacks Rank of 2 (Buy), indicating positive earnings estimate revisions for both companies [3] - CNA has a forward P/E ratio of 10.77, significantly lower than Cincinnati Financial's forward P/E of 25.84 [5] - The PEG ratio for CNA is 4.32, while Cincinnati Financial's PEG ratio is higher at 7.43, suggesting that CNA may be more attractive based on expected earnings growth [5] - CNA's P/B ratio stands at 1.2, compared to Cincinnati Financial's P/B ratio of 1.64, further indicating a more favorable valuation for CNA [6] - Based on these valuation metrics, CNA earns a Value grade of A, while Cincinnati Financial receives a Value grade of C [6] Investment Outlook - Both companies exhibit solid earnings outlooks, but CNA is identified as the superior value option based on the discussed valuation figures [7]
CNXC or TRI: Which Is the Better Value Stock Right Now?
ZACKS· 2025-08-19 16:41
Investors looking for stocks in the Business - Services sector might want to consider either Concentrix Corporation (CNXC) or Thomson Reuters (TRI) . But which of these two stocks presents investors with the better value opportunity right now? Let's take a closer look.There are plenty of strategies for discovering value stocks, but we have found that pairing a strong Zacks Rank with an impressive grade in the Value category of our Style Scores system produces the best returns. The Zacks Rank is a proven str ...
DH vs. BL: Which Stock Should Value Investors Buy Now?
ZACKS· 2025-08-19 16:41
Investors interested in stocks from the Internet - Software sector have probably already heard of Definitive Healthcare Corp. (DH) and BlackLine (BL) . But which of these two stocks offers value investors a better bang for their buck right now? We'll need to take a closer look.There are plenty of strategies for discovering value stocks, but we have found that pairing a strong Zacks Rank with an impressive grade in the Value category of our Style Scores system produces the best returns. The proven Zacks Rank ...
JMPLY vs. APD: Which Stock Should Value Investors Buy Now?
ZACKS· 2025-08-19 16:41
Core Insights - The article compares Johnson Matthey PLC (JMPLY) and Air Products and Chemicals (APD) to determine which stock is more attractive to value investors [1] - JMPLY has a stronger earnings outlook and a better Zacks Rank compared to APD, indicating a more favorable investment opportunity [3] Valuation Metrics - JMPLY has a forward P/E ratio of 12.60, significantly lower than APD's forward P/E of 23.98, suggesting JMPLY is undervalued [5] - The PEG ratio for JMPLY is 3.10, while APD's PEG ratio is 6.43, indicating JMPLY offers better value relative to its expected earnings growth [5] - JMPLY's P/B ratio is 1.43 compared to APD's P/B of 3.61, further supporting the conclusion that JMPLY is the superior value option [6] Value Grades - JMPLY holds a Value grade of A, while APD has a Value grade of D, highlighting JMPLY's stronger position in terms of valuation metrics [6]
Smith-Midland Q2 Earnings Double Y/Y on Record Revenues, Stock Rises
ZACKS· 2025-08-19 16:36
Shares of Smith-Midland Corporation (SMID) have risen 0.8% since reporting second-quarter 2025 results. In contrast, the S&P 500 index has declined 0.2% over the same period. Looking over a longer horizon, the stock has jumped 16.3% in the past month, outperforming the S&P 500’s 2.5% growth. This relative strength highlights investor confidence in the company’s operational momentum amid broader market uncertainty.In its latest quarter, Smith-Midland reported revenues of $26.2 million, up 33% from $19.6 mill ...
FTNT vs. QLYS: Which Cybersecurity Stock Deserves Your Investment?
ZACKS· 2025-08-19 16:36
Core Insights - The cybersecurity market is projected to grow significantly, reaching $351.9 billion by 2030, with Fortinet and Qualys as key players addressing critical security needs [1][2] - Organizations are increasing their security budgets by 15% in 2025 due to escalating cyber threats [2] Fortinet (FTNT) - Fortinet reported a revenue growth of 14% year-over-year to $1.63 billion in Q2 2025, with billings increasing by 15% to $1.78 billion [4] - The company maintains a strong market position with its Security Fabric platform and leadership in network firewalls, but faces challenges in sustaining growth momentum [4][5] - Following its earnings announcement, Fortinet's stock dropped 17% in after-hours trading, indicating investor concerns about future growth despite beating earnings estimates [5] - The guidance for Q3 revenues is between $1.67 billion and $1.73 billion, suggesting a moderation in growth trajectory [5] - The consensus mark for 2025 earnings is $2.51 per share, indicating a 5.91% year-over-year growth [6] Qualys (QLYS) - Qualys demonstrated a 10% revenue growth to $164.1 million in Q2 2025, with 82% GAAP gross margins, showcasing operational efficiency [7] - The launch of the AI-powered Risk Operations Center positions Qualys as a leader in next-generation threat management, with the ability to reduce risk exposure by 85% and accelerate remediation by 70% [7] - Qualys raised its 2025 revenue guidance to $656-662 million, representing 8-9% growth, while maintaining strong profitability metrics [9] - The consensus mark for 2025 earnings is $6.35 per share, indicating a 3.59% year-over-year growth [10] Valuation and Performance Comparison - Fortinet trades at a P/E ratio of 30.18, while Qualys trades at a more attractive P/E ratio of 19.88, indicating better relative value for Qualys [11][8] - Fortinet's stock has dropped over 25% from its 52-week high and is down 14.5% year to date, while Qualys has shown more stability with a decline of 6.8% year to date [14] Conclusion - Qualys is viewed as a more compelling investment opportunity due to its innovative AI-driven platform, superior margins, and attractive valuation [18] - The focus on autonomous risk management positions Qualys for accelerated growth in the face of increasing security threats [18]
TSLY Delivers Yield But Captures The Worst Of Both Worlds
Seeking Alpha· 2025-08-19 16:32
If you look at my analysis history, you will see that I am not a big fan of ETFs that limit upside in exchange for income, and I am also not a big fan of Tesla, Inc. (Equity Research Analyst with a broad career in the financial market, covered both Brazilian and global stocks. As a value investor, my analysis is primarily fundamental, focusing on identifying undervalued stocks with growth potential. Feel free to reach out for collaborations or to connect!Analyst’s Disclosure:I/we have a beneficial long posi ...