Core Insights - NextNRG, Inc. is set to achieve record fuel volumes in Q4 2025, driven by strong holiday demand and effective operational execution [1] Delivery Performance - In Q3 2025, NextNRG delivered approximately 6.5 million gallons, a significant increase from about 1.9 million gallons in Q3 2024 [2] - December 2025 deliveries are projected to reach around 2.5 million gallons, compared to approximately 620,000 gallons in December 2024 [2] - The company anticipates delivering approximately 7.0 million gallons in Q4 2025, marking the highest quarterly fuel volume in its history [3] Operational Efficiency - NextNRG's mobile fueling platform enhances fleet efficiency by providing on-site fueling solutions, reducing downtime during peak demand periods [4] - The company emphasizes operational discipline, customer retention, fleet expansion, and route optimization to capture growing market demand [5] Future Outlook - NextNRG expects to maintain operational momentum into 2026 through ongoing optimization and improved routing efficiency [6] Company Overview - NextNRG integrates AI and machine learning into energy management, focusing on utility infrastructure, battery storage, and mobile fuel delivery [7] - The Next Utility Operating System® optimizes infrastructure across microgrids and fleet operations, contributing to cost savings and decarbonization [8]

Generative vs. discriminative models in ML:(a popular ML interview question) https://t.co/r3c5l3NIDx ...

在工业互联网与智能制造深入推进的背景下，高精度的网络规划与仿真成为实现数字孪生、提升生产效能的关键支撑。面对"工业互联网仿真软件有哪 些？"的常见议题，除广为人知的通用仿真平台外，专注于无线网络规划与仿真的Ranplan Professional与Ranplan Academic正凭借其专业定位与技术深度，在 行业与学术领域展现出独特价值。以下将基于其核心能力与适用场景，展开客观梳理与分析。 NO.1 Ranplan Professional：面向工业场景的无线网络数字孪生专家 Ranplan Professional是一款先进的3D建模与网络仿真平台，致力于为通信运营商、设备商、垂直行业（如智能制造、智慧矿山、港口船舶）提供从设计、规 划到优化的全生命周期网络支撑。其核心价值在于通过高精度数字孪生，在物理部署前预见并解决网络问题，显著降低投资风险与后期整改成本。 当前，以数字孪生为核心的仿真技术正成为工业智能化的关键支柱。Ranplan凭借其在全球超过十年的研发投入（累计近5亿元）与深厚的行业积淀，在无线 网络规划仿真这一细分领域构建了显著的技术优势。对于寻求网络规划可靠性、前瞻性研究能力或专业人才培养的用 ...

Industry Overview - The global oncology market is evolving significantly due to rising cancer incidence and rapid scientific advancements, with the American Cancer Society estimating approximately 2.04 million new cancer diagnoses and over 618,000 cancer-related deaths in the U.S. by 2025 [2] - Aging populations and lifestyle-related risk factors are contributing to higher cancer prevalence, leading to sustained growth in healthcare spending on oncology [2] Innovation in Cancer Care - Breakthroughs in immunotherapies, targeted treatments, and personalized vaccines are expanding therapeutic options beyond conventional chemotherapy and radiation [3] - Immune-based strategies, including checkpoint inhibitors and CAR-T therapies, are harnessing the body's immune system to target tumors, while targeted therapies focus on specific genetic alterations [3] - Emerging technologies like genomic sequencing, AI, and machine learning are enhancing biomarker discovery and supporting earlier diagnosis, improving survival rates and quality of life across several cancer types [4] Pharmaceutical Investment - Major pharmaceutical companies, including Novartis, AstraZeneca, Johnson & Johnson (J&J), Pfizer, AbbVie, Merck, Bristol Myers Squibb, and Eli Lilly, are investing aggressively in oncology portfolios with new therapies such as antibody-drug conjugates and bispecific antibodies [5] - Smaller biotech firms are also crucial in driving innovation through partnerships, licensing agreements, and acquisitions [5] Market Dynamics - Oncology is considered one of the most durable and attractive segments within the global healthcare sector for long-term investors, supported by ongoing innovation and favorable reimbursement dynamics [6] Company Focus: Johnson & Johnson - J&J's oncology segment currently accounts for approximately 27% of its total revenues, with oncology sales rising 20.6% to $18.52 billion in the first nine months, driven by key products like Darzalex and Erleada [9] - J&J's oncology pipeline has gained momentum with promising developments in colorectal and head and neck cancers, and the company expects its oncology sales to reach $50 billion by the end of the decade [10][12] - J&J is also enhancing its oncology pipeline through M&A, including a recent agreement to acquire Halda Therapeutics [11] Company Focus: ImmunityBio - ImmunityBio's lead drug, Anktiva, was approved for treating BCG-unresponsive non-muscle invasive bladder cancer, generating $74.7 million in sales with a 467% increase in volume [13] - The drug is under review in the EU, and ImmunityBio is evaluating Anktiva for expanded use in other cancer indications [15] Company Focus: Foghorn Therapeutics - Foghorn Therapeutics is developing precision therapies targeting genetically driven vulnerabilities, with a collaboration with Lilly to co-develop its selective SMARCA2 oncology program [17] - Foghorn's lead candidate, FHD-909, is advancing in a phase I study for SMARCA4-mutated cancers, with initial data expected in 2026 [17][18]

Core Insights - NetraMark Holdings Inc. has made significant progress in commercial execution, regulatory engagement, and scientific validation, strengthening its growth trajectory in AI-driven clinical trial optimization [1][2] Group 1: Contract Backlog and Financial Outlook - The contract backlog for NetraMark increased to approximately C$2.5 million, driven by new project commitments and commercial momentum, with a target of reaching C$8–$10 million by mid-2026 [2][4] - The company is experiencing growing commercial traction and expanding channel partnerships, which support its financial outlook [4] Group 2: Regulatory Engagement - NetraMark completed a Critical Path Innovation Meeting (CPIM) with the FDA, receiving feedback on its NetraAI platform and its application in clinical trial design [2] - The FDA discussed considerations for identifying responder-enriched subgroups while maintaining control of Type I error, aligning with FDA enrichment guidance [2] Group 3: Scientific Validation - A scientific study on NetraAI was accepted for publication in npj Digital Medicine, demonstrating its ability to identify clinically meaningful subgroups in a Phase II depression trial [2] - The acceptance by a high-impact journal provides third-party validation of NetraMark's scientific approach [2] Group 4: Strategic Collaborations - NetraMark secured an Ontario Research Fund – Research Excellence Award in collaboration with the Centre for Addiction and Mental Health (CAMH), focusing on analyzing genetic and epigenetic data in psychiatric disorders [2] - This collaboration aims to enhance NetraAI's capabilities in identifying explainable patient subpopulations [2]

BRANFORD, Conn., Dec. 17, 2025 /PRNewswire/ -- Azitra, Inc. (NYSE American: AZTR), a clinical stage biopharmaceutical company focused on developing innovative therapies for precision dermatology, today announced it received a notice from the staff of NYSE American LLC (the "Exchange") approving Azitra's plan (the "Plan") to come into compliance with the Exchange's continued listing standards under Section 1003(a)(ii) of the NYSE American Company Guide. As previously reported, on October 1, 2025, Azitra rec ...

Industry Overview - The global payments industry is experiencing a positive growth environment, driven by the transition to digital and electronic payment methods, with consumer spending continuing to grow [2] - The U.S. central bank has lowered interest rates three times in 2025, which supports consumer spending and improves credit conditions, potentially boosting payment volumes [3][4] - Companies in the payment industry are pursuing mergers and acquisitions to diversify their revenue streams and stabilize their top line [5] Growth Drivers - The quality of growth in the payments space is improving, with revenues increasingly driven by value-added services such as fraud prevention and data analytics [6] - Continued innovation and enhanced security in transactions are expected to benefit payment companies [7] - Real-time and account-to-account payments are gaining traction, increasing overall transaction frequency and creating a favorable backdrop for payment stocks [8] Company Highlights - **Capital One Financial Corp. (COF)**: Expected to benefit from growing consumer loan demand, solid credit card operations, and opportunistic buyouts, with a projected earnings growth of 1.5% and revenue growth of 17.4% for 2026 [10][11][12] - **OppFi Inc. (OPFI)**: Focus on AI and machine learning is expected to improve operating efficiency and support margin expansion, with projected earnings growth of 8.6% and revenue growth of 9.1% for 2026 [13][14] - **SoFi Technologies, Inc. (SOFI)**: Innovation and an expanding digital financial ecosystem are expected to drive growth, with projected earnings growth of 62.9% and revenue growth of 25.4% for 2026 [15][16]

In 2023, Kalyani Ramadurgam founded Kobalt Labs with former Affirm software engineer Ashi Agrawal to bring compliance into the machine-learning age. Kobalt's AI models sort through mountains of documents to help banks vet their business partners, ensuring they're following the rules, like halting money transfers from sanctioned countries and promptly disclosing security breaches. #ForbesUnder30Read more: https://t.co/Pq2lx0UdZgPhoto: Sebastian Nevols for Forbes ...

Summary of Tantalus Systems Holding Update / Briefing Company Overview - **Company**: Tantalus Systems Holding (OTCPK:TGMP.F) - **Industry**: Utility Management and Smart Metering Solutions Key Points and Arguments Remote Disconnect and Customer Management - Tantalus offers remote disconnect capabilities that allow utilities to manage customer power supply effectively, even in cases of non-payment, through prepay programs [1] - The system enables utilities to maintain power for customers by automatically reconnecting service when payment thresholds are met, enhancing customer satisfaction and reducing trip charges [1] Interval Success Rate and Data Accuracy - Tantalus measures its performance against specific intervals for meter readings, aiming for high accuracy in data collection [2] - The company emphasizes the importance of real-time data collection, allowing utilities to respond quickly to customer inquiries and issues [5][6] Customer Service Enhancements - The system provides detailed customer data, enabling utility representatives to address high bill complaints effectively by analyzing usage patterns and potential causes [4][10] - Tantalus allows utilities to communicate effectively with customers about their energy usage, reducing frustration and improving customer relations [9] Advanced Metering Infrastructure (AMI) - Tantalus does not manufacture meters but integrates its technology into third-party meters, enhancing data collection capabilities [38] - The TruSense Gateway device captures extensive data, providing utilities with real-time insights into power quality and consumption [39] AI and Machine Learning Integration - Tantalus is leveraging AI and machine learning to enhance the functionality of its systems, allowing for predictive analytics and better grid management [28] - The company aims to transform traditional utility equipment into smart devices, improving operational efficiency and decision-making [28] Transformer Monitoring and Management - Tantalus provides utilities with the ability to monitor transformer performance, identifying overloads and potential failures before they occur [29][31] - The system helps utilities manage reverse power flow, which can pose safety risks if not monitored properly [30] Idle and Underloaded Transformers - The company addresses the issue of idle transformers, which can incur unnecessary costs for utilities, by providing data to identify and manage these assets effectively [34] - Tantalus also helps utilities monitor underloaded transformers to prevent issues that could affect service quality [35] Utility Adoption and Market Presence - As of Q3 results, Tantalus has over 330 utilities deploying its capabilities, with ongoing efforts to expand its market presence [40] - The company is actively working with utilities to enhance their operational capabilities and address the challenges posed by increasing electrification and energy demand [41] Future Developments and Challenges - Utilities are seeking more innovative solutions to manage power constraints and improve service delivery, which Tantalus aims to provide through its advanced technology [44] - Funding remains a significant barrier for some utilities in adopting new technologies, impacting deployment timelines [50] Additional Important Insights - Tantalus emphasizes the importance of real-time data and proactive communication between utilities and customers to enhance service quality [37] - The company is focused on educating utilities about its systems to ensure effective implementation and utilization of data [16] This summary encapsulates the key points discussed in the Tantalus Systems Holding update, highlighting the company's innovative solutions and the challenges faced in the utility industry.

Industry Overview - The global payments industry is experiencing a positive growth environment, driven by the transition to digital and electronic payment methods, with consumer spending on the rise [1] - Cards, digital wallets, and online checkouts are steadily replacing cash, leading to a consistent volume boost and long-term revenue prospects for leading payment companies [1][10] - Monetary policy has become a modest tailwind, with the U.S. central bank lowering interest rates three times in 2025, which is expected to support consumer spending and improve credit conditions [2][3] Growth Drivers - Lower interest rates are anticipated to enhance consumer spending and credit conditions, which will positively impact payment volumes heading into 2026 [3][10] - Companies in the payment industry are pursuing mergers and acquisitions to diversify their revenue streams and stabilize their top line [4] - The quality of growth in the payments space is improving, with revenues increasingly driven by value-added services such as fraud prevention and data analytics [4] Company Highlights - Capital One Financial Corporation (COF) is expected to benefit from growing consumer loan demand, solid credit card operations, and opportunistic buyouts, with a projected earnings growth of 1.5% and revenue growth of 17.4% in 2026 [8][9] - OppFi Inc. (OPFI) is focusing on AI and machine learning to improve operational efficiency, with earnings and revenue growth estimates of 8.6% and 9.1% respectively for 2026 [12][13] - SoFi Technologies, Inc. (SOFI) is enhancing its digital financial ecosystem and is projected to see significant earnings growth of 62.9% and revenue growth of 25.4% in 2026 [16][17] Stock Performance - Capital One Financial shares have gained 32.4% over the past year, while the industry has risen by 54.5%, and it currently holds a Zacks Rank 1 [11] - OppFi's shares have increased by 38.4% in the past year, contrasting with the industry's decline of 9.6%, and it also holds a Zacks Rank 1 [13] - SoFi's shares have soared 55% over the past year, while the industry has fallen by 12.6%, and it carries a Zacks Rank 2 [17]