禁忌症 ：司美格鲁肽不适用于1型糖尿病患者或用于治疗糖尿病酮症酸中毒，也不是胰岛素的替代品。如果有甲状腺髓样癌的个人或家 族病史，或者患有2型多发性内分泌肿瘤综合征（MEN 2），则不应使用司美格鲁肽。 ▍ 司美格鲁肽等GLP-1类药物的首次使用注意事项 起始剂量和逐步增加 ：通常建议从小剂量0.25 mg开始，每周一次，并根据医嘱逐渐增加剂量。不建议单次注射剂量超过1 mg。 使用方法 ： 口服司美格鲁肽的推荐服用方式是 每天早餐前 以不超过4盎司（ 约120毫升 ）水送服，服药后 至少间隔30分钟 再吃早餐、 饮料或其他口服药物。此外，患者在服用时应整片吞服药物，不要切割、压碎或咀嚼药片。 司美格鲁肽注射液通过皮下注射给药，推荐的注射部位是腹部、大腿外侧和上臂。注射时应使用新的一次性无菌针头，并在每次注射后 和储存时取下针头。 储存条件 ： 口服剂型在贮藏 方 面 更为灵活，不需要冷藏 条件。 而 未开封的司美格鲁肽注射液应储存于冰箱中（2℃-8℃），首次使用后可在30℃以下环境或冷藏于冰箱中保存，最多可保存6周。切勿 冷冻本品。 监测血糖 ：使用司美格鲁肽期间，应定期监测血糖水平，并在医生的指导下进行必 ...

Core Viewpoint - The article emphasizes the importance of a balanced diet and nutritional management for individuals using GLP-1 receptor agonists like semaglutide for weight loss, highlighting that medication alone is insufficient for effective weight management [4][6]. Group 1: Nutritional Considerations - Users of semaglutide should focus on the nutritional density of their food, as rapid weight loss can lead to a decrease in muscle mass [6][7]. - It is crucial for users to ensure adequate intake of high-quality protein, fiber, and hydration, while considering the potential need for multivitamins to address nutritional gaps [7][9]. - A balanced plate should include approximately 85-113g of protein, 170g of non-starchy vegetables, and 85g of starch, although many users may struggle to achieve this balance [7][9]. Group 2: Foods to Avoid - High-fat foods, especially fried and heavily oil-based dishes, should be avoided as they can cause gastrointestinal discomfort during semaglutide use [9][11]. - Foods high in trans fats and saturated fats, such as full-fat dairy and red meats, can exacerbate digestive issues and affect medication efficacy [9][11]. - High-sugar foods, including desserts and sugary beverages, should be strictly limited to prevent blood sugar fluctuations, particularly for diabetic patients [9][11]. - High-sodium foods and refined carbohydrates should also be minimized to reduce health risks, especially for those with type 2 diabetes [11][12]. - Alcohol consumption is discouraged as it can aggravate digestive problems and increase the risk of hypoglycemia [12].

Core Viewpoint - The article discusses the launch of the weight loss drug Semaglutide (brand name: Novo Nordisk) in China and emphasizes the importance of a holistic approach to weight loss that includes dietary changes alongside medication use [1][3]. Group 1: Drug Overview and Usage - Semaglutide was officially launched in China on November 17, leading to an increase in consultations at weight loss and endocrinology clinics [1]. - The use of weight loss medications requires standardized management, as relying solely on drugs is insufficient for effective weight loss [1][3]. Group 2: Nutritional Considerations - Users of Semaglutide should focus on the nutritional density of their food, as rapid weight loss can lead to a decrease in muscle mass [3][4]. - It is crucial for users to ensure adequate intake of high-quality protein, fiber, and hydration, as well as to consider taking multivitamins to address potential nutritional gaps [5][4]. Group 3: Recommended Dietary Practices - A balanced plate should include protein, vegetables, and starches tailored to individual health conditions and preferences [5]. - Specific recommendations include consuming 85-113g of protein, 170g of non-starchy vegetables, and 85g of starch per meal, although many users may struggle to achieve this balance [5]. Group 4: Foods to Avoid - High-fat foods, such as fried items and those cooked in heavy oils, should be avoided as they can cause gastrointestinal discomfort, especially when using Semaglutide [7]. - Foods high in trans fats and saturated fats, such as full-fat dairy and red meats, can exacerbate digestive issues and affect the drug's efficacy [7]. - High-sugar foods and refined carbohydrates should be limited, as they can lead to blood sugar spikes and interfere with the medication's effects [10][9]. - Alcohol consumption should be minimized or avoided due to its potential to aggravate digestive problems and increase the risk of hypoglycemia [11].