Investment Rating - The industry investment rating is optimistic (maintained) [1] Core Viewpoints - The pharmaceutical industry is experiencing significant differentiation, with innovative drugs, raw materials, and CXO sectors performing well [2][3] - The overall performance of the pharmaceutical industry in 2024 and the first half of 2025 is under pressure, with notable declines in consumer segments, while innovative drugs, raw materials, and CXO show strong growth [2] Summary by Relevant Sections Overall Industry Performance - In 2024, 453 pharmaceutical companies achieved revenue of 2.46 trillion yuan, a year-on-year decline of 0.55%, and a net profit of 148.65 billion yuan, down 8.8%. In the first half of 2025, revenue was 1.22 trillion yuan, a decrease of 2.5%, with net profit at 102 billion yuan, down 2.1% [2][68] Innovative Drugs - In the first half of 2025, innovative drug companies generated revenue of 26.964 billion yuan, a year-on-year increase of 11.78%. Domestic innovative drug companies are transitioning from R&D to commercialization, marking a turning point towards profitability [2][10] Chemical Drugs - Chemical drug companies reported revenue of 198.06 billion yuan in the first half of 2025, a decline of 3.83%, with net profit at 22.14 billion yuan, down 0.11%. Traditional generic to innovative drug companies are performing better [2][10] Medical Devices - Medical device companies achieved revenue of 106.82 billion yuan in the first half of 2025, down 5.32%, with net profit at 17.58 billion yuan, down 18.07%. The sector is under pressure due to inventory and policy impacts, but high-value consumables are showing better performance [2][10] Biological Products - Blood products revenue in 2024 was 24.18 billion yuan, down 1.4%, with net profit of 6.23 billion yuan, up 14.47%. Vaccine companies faced significant declines, with 2024 revenue at 40.77 billion yuan, down 45.3% [2][10] Traditional Chinese Medicine - In the first half of 2025, traditional Chinese medicine companies reported revenue of 174.38 billion yuan, down 4.57%, with net profit of 22.48 billion yuan, up 0.70%. The sector is under pressure from regulatory policies and weak consumer demand [2][10] Raw Materials - Raw material companies achieved revenue of 47.86 billion yuan in the first half of 2025, down 2.90%, but net profit increased by 20.61% to 8.10 billion yuan. High-demand segments like peptides are performing well [2][10] Pharmaceutical Commerce - Pharmaceutical commerce companies reported revenue of 517.86 billion yuan in the first half of 2025, flat year-on-year, with net profit of 12.09 billion yuan, up 7.6% [5] Medical Services - Medical service companies achieved revenue of 36.36 billion yuan in the first half of 2025, down 4.93%, with net profit of 2.35 billion yuan, down 11.17% [5] CXO & Research Services - The CXO and research services sector reported revenue of 50.64 billion yuan in the first half of 2025, up 13.05%, with net profit of 11.91 billion yuan, up 60.6% [5]

Overall Industry Summary - In 2024, 453 pharmaceutical companies achieved revenue of 2.46 trillion yuan, a year-on-year decline of 0.55%, and a net profit of 148.65 billion yuan, down 8.8% [1] - In the first half of 2025, revenue is expected to be 1.22 trillion yuan, a decrease of 2.5%, with a net profit of 102 billion yuan, down 2.1% [1] Innovative Drugs - In the first half of 2025, innovative drug companies achieved revenue of 26.964 billion yuan, a year-on-year increase of 11.78%, indicating strong momentum [1] - Domestic innovative drug companies are transitioning from R&D to commercialization, marking a turning point towards profitability [1] - Outbound licensing has become a second growth curve for biotech companies, providing sustainable funding for R&D through high upfront payments [1] Chemical Drugs - In the first half of 2025, chemical drug companies reported revenue of 198.057 billion yuan, a decline of 3.83%, with a net profit of 22.139 billion yuan, down 0.11% [1] - Traditional generic-to-innovative drug companies performed well, with notable examples including Hengrui Medicine and Haizheng [1] - The chemical drug sector is expected to further differentiate, with innovative companies likely to benefit in the medium to long term [1] Medical Devices - In the first half of 2025, medical device companies achieved revenue of 106.82 billion yuan, down 5.32%, and a net profit of 17.58 billion yuan, down 18.07% [2] - The performance of high-value consumables is driven by factors such as inventory levels and policy impacts, suggesting potential turning points and innovation opportunities [2] Biological Products - Blood products in 2024 generated revenue of 24.18 billion yuan, down 1.4%, with a net profit of 6.23 billion yuan, up 14.47% [2] - Vaccine companies faced significant declines, with 2024 revenue of 40.77 billion yuan, down 45.3%, and a net profit of 3.2 billion yuan, down 72% [2] Traditional Chinese Medicine - In the first half of 2025, traditional Chinese medicine companies reported revenue of 174.376 billion yuan, down 4.57%, with a net profit of 22.479 billion yuan, up 0.70% [3] - The sector is under pressure due to stricter regulations and weak consumer demand, but there are opportunities for leading OTC brands and innovative companies [3] Raw Materials - In the first half of 2025, raw material drug companies achieved revenue of 47.86 billion yuan, down 2.90%, with a net profit of 8.1 billion yuan, up 20.61% [3] - High-performing segments include peptides and vitamin E/A, with companies like Nuotai Bio and New Hecheng showing strong results [3] Pharmaceutical Commerce - In the first half of 2025, pharmaceutical commerce companies reported revenue of 517.86 billion yuan, flat year-on-year, with a net profit of 12.09 billion yuan, up 7.6% [4] - Offline pharmacies achieved revenue of 57.77 billion yuan, up 0.1%, and a net profit of 2.55 billion yuan, up 0.9% [4] Medical Services - In the first half of 2025, medical service companies reported revenue of 36.36 billion yuan, down 4.93%, with a net profit of 2.352 billion yuan, down 11.17% [5] - The performance of eye care companies showed growth, with revenue of 16.102 billion yuan, up 6.75% [5] CXO & Research Services - In the first half of 2025, the CXO and research services sector achieved revenue of 50.64 billion yuan, up 13.05%, with a net profit of 11.91 billion yuan, up 60.6% [6] - The sector continues to show improvement, with leading CXO companies demonstrating strong resilience and growth [6]