种子是农业的"芯片"，是国家粮食安全的命脉。12月22日，中国科学院在北京举行A类先导专 项"种子精准设计与创造"（以下简称"种子专项"）系列科研成果发布会，介绍种子专项通过创建精准设 计育种新范式，在打造种业振兴的"中国芯"方面取得的系列突破。 从田间到餐桌，赋能全产业链 精准设计育种正从实验室快速走向广袤的田野和百姓的餐桌，在作物和水产等多个领域结出硕果。 大豆，是我国进口依赖度最高的粮油作物。种子专项研究团队绘制了全球领先的大豆图形结构泛基 因组图谱，并开发了功能强大的大数据平台SoyOmics。利用这些工具，科学家能够像"拼乐高"一样， 精准聚合高产、高油、高蛋白等优良性状。种子专项成功培育出"科豆""东生"系列等10个高产高营养大 豆新品种。 "经过六年攻关，种子专项取得了覆盖理论、技术、产品的全链条体系化突破，提出了新理论，开 发了新技术，推出了新产品。"种子专项首席科学家、中国科学院院士李家洋说。 找到"基因钥匙"，破解生产难题 面对化肥过量施用、病虫害威胁加剧、资源约束趋紧等难题，种子专项的科学家们不再仅仅依靠传 统经验，而是拿起"精准设计"这一全新工具，为种子注入"智慧"，直面生产痛点。 如 ...

Core Insights - Zhongnong Zhongyuan (Shenzhen) Technology Co., Ltd. has completed a Series A financing round, raising a significant amount in RMB, with investors including Songhe Capital and Sanze Venture [1][2]. Financing Details - The financing round was announced on November 2, 2025, with Songhe Capital participating and the amount being in the billion RMB range [2]. - Previous funding rounds include a Pre-A round by Lenovo Capital on August 10, 2023, with undisclosed amounts, and an angel round by HongShan Sequoia China on February 8, 2023, raising tens of millions in RMB [2]. Company Focus - Zhongnong Zhongyuan is established in collaboration with the Shenzhen Agricultural Genomics Institute of the Chinese Academy of Agricultural Sciences, focusing on advanced breeding technology for pigs and the creation of breeding materials [1][2]. - The company is engaged in research related to pig genomics and breeding, gene engineering, and experimental miniature pigs, with a focus on developing new breeding materials through gene editing [2]. - The team has developed several gene-edited breeding materials that confer resistance to major diseases such as blue ear disease and infectious gastroenteritis, and has completed relevant patent arrangements [2]. - The company has also obtained certification for three model pig strains as new resources for experimental animals, marking the first successful identification of gene-edited pig disease model strains [2].

Core Insights - The article discusses a groundbreaking research study that successfully established haploid embryonic stem cells (haESC) in cattle and sheep, overcoming previous limitations in breeding these ruminants [3][4][5] - The study introduces a novel breeding strategy combining haESC, spermatid-like modifications, and non-integrative prime editing (ePE), leading to significant advancements in genetic editing of livestock [3][9] Group 1: Research Breakthroughs - The research team successfully created haploid embryonic stem cell lines from cattle and sheep, which exhibit pluripotent characteristics and can differentiate into three germ layers [4] - The innovative "Pro-iCHI" technique, which involves injecting haESC into oocytes, significantly improved the full-term development rate of embryos [4][5] - The study achieved a 100% editing efficiency for the MSTN gene, which is known to inhibit muscle growth, leading to a potential increase in muscle mass of 20%-30% in cattle and sheep [5][6] Group 2: Implications for Livestock Breeding - Traditional methods for gene editing in livestock resulted in a low birth rate of less than 5%, but the new Pro-iCHI technique combined with ePE achieved a birth rate of 13.3% for genetically edited animals [5] - The research opens new pathways for efficient breeding of genetically modified livestock, potentially transforming the agricultural industry [9] - The findings were highlighted in a related article in Nature Biotechnology, emphasizing the potential for rapid generation of genome-edited farm animals from haploid stem cells [6]

Core Insights - The National Standard Material approval has reached 19,007 items, maintaining China's leading position in international metrology recognition [1][2] - From January to July, 549 new national standard materials were approved, representing a 56% year-on-year increase, indicating strong demand in both production and research [1] Group 1: Traditional and Emerging Fields - Traditional fields, particularly environmental monitoring, remain the foundation for standard materials, with 205 items approved from January to July, accounting for 37.3% of the total and a 64% year-on-year increase [1] - Emerging sectors such as high-end biomedicine and new semiconductor manufacturing are also seeing growth, addressing key measurement technology challenges [1] Group 2: Production and Research Dynamics - Enterprises produced 401 standard materials from January to July, making up 73% of the total, with a 68.5% year-on-year increase, all classified as national secondary standard materials [2] - Research institutions produced 148 standard materials, accounting for 27% of the total, with a 29.8% year-on-year increase, including 31 national primary and 117 secondary standard materials [2] Group 3: Regional Concentration and Development - The North China region shows a high concentration in standard material production, with 244 items approved, representing 44.4% of the total and a 165.2% year-on-year increase [2] - Beijing, leveraging its rich research resources, leads in the production of standard materials, particularly in food safety monitoring and steel manufacturing [2] Group 4: Future Directions - The National Market Regulation Administration plans to enhance the capacity for national standard materials, focusing on urgent societal and industrial needs to support high-quality economic development [2]

以下文章来源于RimeData 来觅数据 ，作者来觅研究院 导读：4月7日，中共中央、国务院印发《加快建设农业强国规划（2024-2035）》，其中提到要推动种业自主创新全面突破，加强种质资 源保护利用，建设国际一流的国家农业种植资源保存、鉴定、创制和基因挖掘重大设施。实施育种联合攻关和畜禽遗传改良计划，加快建 设南繁硅谷。实施生物育种重大专项，选育高油高产大豆、耐盐碱作物等品种，加快生物育种产业化应用。 01 生物育种 生物育种是指利用现代生物学技术（如基因工程、分子标记、细胞工程等）结合传统育种方法，对动植物进行遗传改良，以获得优良性状（如高产、抗 病、耐逆、优质等）的新品种的过程，其核心是通过操控生物体的遗传物质（DNA）来定向优化目标性状，提高农业生产效率。 全球大力发展生物育种技术，主要是为了应对传统种植方法存在的诸多问题，如育种效率低、抗逆性差、资源利用效率低以及难以满足多样化市场需求 等。生物育种技术凭借其精准高效、抗逆性强、资源利用高效等优势，能显著提高粮食产量，保障粮食安全，同时推动农业的智能化和可持续发展。生物 育种技术已成为现代农业发展的关键驱动力，对于提升农业竞争力、应对资源约束以及推 ...