相关论文发表在美国专业期刊《干细胞报告》上。 英国伯明翰大学等机构的研究人员利用干细胞培育出人体泪腺的"类器官"，即具备特定关键功能的微型 器官，用基因工具扰乱其细胞自噬机制。结果发现，泪腺类器官的细胞组成失衡，泪液蛋白质分泌显著 减少，细胞死亡增加，与干眼症患者的情况一样。 研究人员进一步发现，对于泪腺类器官，烟酰胺单核苷酸和褪黑素可以缓解自噬机制紊乱带来的细胞功 能失调，减少细胞死亡，恢复泪液蛋白质的分泌。 新华社伦敦1月4日电 一项国际研究通过干细胞实验发现，如果泪腺的"细胞垃圾回收"即自噬机制发生 紊乱，会导致泪液分泌异常，这可能是引发干眼症的重要原因。这为治疗干眼症提供了新思路。 泪腺持续分泌泪液，对眼球起到润滑和保护作用，其中的蛋白质有着重要的抗菌和免疫功能。泪腺的自 噬机制销毁受损的细胞器和蛋白质等，将其分解成原材料回收利用，对防止废物累积、预防疾病至关重 要。而干眼症患者的泪液分泌异常，导致眼睛干涩、有刺激感、疲劳等，严重时会影响视力。 ...

干眼症是眼科常见病，我国约3亿人受其困扰。了解干眼症的预防和治疗方法，养成良好的用眼习 惯，可以有效减少干眼症的发生。今天，眼科专家针对"干眼打工人"普遍关心的问题，进行权威解答。 干眼症能根治吗 多数干眼症患者通过合理的治疗和护理可以有效控制症状。部分有明确病因引起的干眼症（如某些 药物副作用、眼部手术后等），在去除病因后可能会得到改善甚至痊愈。但大多数患者需要长期坚持治 疗和良好的用眼习惯，才能维持眼部健康。一旦过度用眼或者熬夜，可能导致症状卷土重来。 干眼还能戴隐形眼镜吗 能否佩戴隐形眼镜取决于干眼症状的严重程度。轻症患者，必要时可短时佩戴隐形眼镜，同时需注 意摘戴的卫生条件。干眼症状比较明显的患者，尽量避免戴隐形眼镜。因为，隐形眼镜会加重眼部干涩 不适，如果上皮有损伤，还会显著增加感染的风险。 眼干又须用电子产品怎么办 调整用眼习惯定时休息，遵循"20-20-20"规则，即每20分钟看远处20英尺（约6米）的地方，持续 20秒，让眼睛得到休息；有意识地多眨眼，帮助泪液均匀分布在眼表面，减少干涩。 优化工作环境调整屏幕位置，屏幕应位于眼睛水平线稍下方，距离眼睛约50-70厘米，使睑裂暴露 在空气中的宽度 ...

Core Viewpoint - Dry eye syndrome is a common eye condition affecting one in three people in China, often exacerbated by daily habits and environmental factors [2][15]. Group 1: Symptoms of Dry Eye Syndrome - Typical symptoms include dryness, foreign body sensation, burning or stinging, and eye fatigue [4][5][6][7]. - Visual symptoms consist of blurred vision, light sensitivity, and temporary vision fluctuations [8][9][10]. - Other accompanying symptoms may include redness, increased tearing, and difficulty wearing contact lenses [10][11]. Group 2: Risks and Complications - Long-term dry eye can lead to permanent vision damage, decreased quality of life, increased risk of infections, and exacerbation of other eye diseases [15][17][18][19]. - Chronic inflammation and eye surface damage can create a vicious cycle, making treatment more difficult [19]. Group 3: Causes and Contributing Factors - Dry eye syndrome has complex causes, including age, autoimmune diseases, medication effects, and environmental factors [21]. - Poor eye habits, such as prolonged contact lens wear, excessive screen time, and improper use of eye drops, significantly contribute to the condition [21][22][23][24]. Group 4: Prevention and Management Strategies - Recommended strategies include the 20-20-20-2 rule, adjusting screen height, and using warm compresses to improve blood circulation [26][27]. - Dietary adjustments, such as increasing intake of unsaturated fatty acids and vitamins, are also suggested to support eye health [27].

Group 1 - The "2025 National Vision Health Popularization Action" was officially launched in Beijing, focusing on building an eye health ecosystem through multi-party collaboration [1] - Dr. Luo Yan from Peking Union Medical College Hospital emphasized the importance of comprehensive pre-operative assessments and scientific post-operative care for adult myopia correction surgeries [1][3] - The two main types of adult myopia correction surgeries are corneal laser surgery and intraocular lens surgery, with the latter offering a wider correction range and higher safety [3] Group 2 - For patients with high myopia, post-operative eye care is crucial to prevent further deterioration and retinal diseases, with recommendations for regular eye examinations every 3-5 years [3] - Patients with dry eye syndrome should select surgical methods based on the severity of their condition, with mild cases being less impactful on surgery outcomes [3] - Dr. Luo highlighted that patients with moderate to severe dry eye may benefit more from intraocular lens implantation, which has less impact on the cornea and faster vision recovery [3]

Core Viewpoint - The 30th National Eye Care Day emphasizes the importance of eye health awareness, particularly focusing on the increasing prevalence of dry eye syndrome among younger individuals due to lifestyle and environmental factors [1][2]. Group 1: Dry Eye Syndrome Overview - Dry eye syndrome is defined as an imbalance in the eye's tear film stability or microenvironment, leading to discomfort or visual fluctuations [1]. - Common symptoms include dryness, foreign body sensation, redness, light sensitivity, and even tearing in some cases [1]. Group 2: Causes and Risk Factors - Various factors contribute to the onset of dry eye syndrome, including unhealthy work habits, environmental conditions (e.g., wind, sand, haze), and age [2]. - The incidence of dry eye syndrome increases with age, and hormonal changes during menopause can also elevate risk, particularly in women [2]. Group 3: Treatment Approaches - Treatment for mild dry eye syndrome primarily involves the use of artificial tears to lubricate the eye surface and alleviate discomfort [2]. - For moderate cases, anti-inflammatory medications and physical treatments such as eyelid hygiene, warm compresses, and massage may be employed [2]. - Severe cases may require surgical interventions, including punctal occlusion or tear duct occlusion procedures [2].

Core Viewpoint - Eye fatigue is a significant issue for entrepreneurs, often overlooked amidst the focus on financing, product iteration, and team management. It can lead to various symptoms that affect overall well-being and productivity, highlighting the importance of eye health in daily routines [1][2]. Group 1: Symptoms and Effects of Eye Fatigue - Common symptoms of eye fatigue include dryness, soreness, blurred vision, and headaches, which can lead to decreased work efficiency and overall discomfort [1][2]. - Prolonged exposure to screens causes the ciliary muscles in the eyes to remain tense, resulting in eye fatigue and potential vision decline [2][3]. Group 2: Bad Habits Affecting Eye Health - Incorrect mobile phone usage posture, such as lying down or looking down for extended periods, can lead to conditions like acute comitant esotropia and increased strain on the neck and spine [5]. - Using screens in poorly lit environments or with inappropriate brightness can exacerbate eye strain, leading to conditions like glaucoma [6]. - The use of privacy screen protectors can reduce screen brightness, forcing the eyes to work harder to see content, which can increase fatigue [7]. - Wearing improperly maintained glasses or contact lenses can lead to further eye strain and potential vision issues [8]. Group 3: Additional Factors Impacting Eye Health - Expired eye drops can lead to infections and serious complications if used beyond their recommended period [9]. - Rubbing the eyes can cause damage to the cornea and increase the risk of infections due to bacteria on the hands [10]. - The use of unwashed eye masks can lead to infections, while improper lighting in living spaces can contribute to eye fatigue [10]. Group 4: Recommendations for Eye Care - Awareness of eye fatigue as a silent threat is crucial, and correcting bad habits is necessary to prevent further deterioration [11]. - Maintaining proper lighting, adjusting screen distance, and taking regular breaks can help alleviate eye strain [11].

Core Viewpoint - The article discusses the proposal by Yao Ming during the National People's Congress to initiate a "screen-free 24 hours" action for minors, aiming to reduce excessive screen time and encourage real-world experiences [1][2]. Group 1: Proposal Details - Yao Ming suggests that parents and schools should participate in a designated day each semester where everyone refrains from using mobile phones for 24 hours, allowing children to experience the real world [2]. - The initiative is likened to traditional school outings, emphasizing the need for children to disconnect from electronic environments [2]. - Yao highlights a common consensus that children are spending too much time on screens, which diminishes communication between children and their parents [2][4]. Group 2: Health Concerns - A case study is presented about a 9-year-old boy diagnosed with dry eye syndrome after excessive screen time during the winter break, illustrating the health risks associated with prolonged use of electronic devices [6][7]. - Statistics indicate that approximately 360 million people in China suffer from dry eye syndrome, with a rising trend among younger populations [9]. - Research shows that among individuals using electronic devices for over 8 hours daily, the incidence of dry eye syndrome can reach 60% [9]. Group 3: Recommendations - The article suggests that parents should manage their children's screen time and encourage physical activities to promote overall well-being [11]. - It is advised that parents seek professional medical attention if children exhibit symptoms like dry eyes or light sensitivity [11].