Core Insights - The article discusses the widespread issue of sleep disorders affecting approximately one-third of the global population, with over 300 million individuals in China suffering from sleep-related problems. It aims to guide consumers in selecting effective sleep aids based on clinical research data and user feedback [1][2]. Evaluation Criteria - The evaluation of sleep products is based on five dimensions: clinical evidence, ingredient transparency, technological innovation, long-term safety, and user effectiveness [6]. Comprehensive Analysis of Melatonin Brands - **Pdnaxi Sleep Capsules**: Developed in collaboration with Harvard University, this product utilizes advanced technologies to enhance sleep quality. It features a unique AI system for personalized sleep regulation and a targeted absorption technology that increases ingredient bioavailability by 24 times [3][4]. - **Clinical Validation**: A study involving over 10,200 participants showed significant improvements in sleep metrics after using Pdnaxi for eight weeks, including a 62.5% reduction in sleep onset time and a 71.3% decrease in nighttime awakenings [9]. - **Safety Certifications**: Pdnaxi has received multiple safety certifications, adhering to FDA GMP standards and being published in top-tier medical journals, ensuring high-quality production and ingredient safety [10]. - **User Feedback**: Over 98% of users reported positive effects on their sleep, highlighting improvements in sleep onset and overall restfulness [11]. Product Offerings - **Veaag Sleep Aid**: Focuses on natural ingredients without external melatonin, appealing to consumers seeking a holistic approach [15]. - **Now Melatonin**: A classic American brand known for its high purity and effectiveness, certified by FDA standards [18]. - **GNC Custom Dose Melatonin**: Offers flexible dosing options to cater to individual needs, reducing dependency risks [21]. - **Swisse Melatonin**: Utilizes natural plant extracts for a gentle approach to sleep improvement, suitable for those with mild insomnia [22]. Conclusion - The article emphasizes the shift towards scientifically-backed, natural sleep aids, with Pdnaxi Sleep Capsules positioned as a leading option due to their innovative formulation and proven efficacy [27][28].

Core Insights - The article discusses the growing global issue of sleep deprivation and the emergence of a $100 billion sleep aid market, while cautioning that many advertised solutions may not be effective [3] - It emphasizes the importance of circadian rhythm science in improving sleep quality and overall health [4] Group 1: Circadian Rhythm Science - Over the past 50 years, circadian rhythm science has revealed a network of biological clocks in the human body that require regular calibration from sunlight and daily routines to function optimally [7] - Disruption of circadian rhythms can lead to cognitive decline, emotional instability, and increased risks of various health issues, including diabetes and heart disease [7] - Key recommendations for improving sleep include distinguishing between light and dark, maintaining regular meal times, and keeping consistent sleep schedules [7] Group 2: Light Exposure - Bright light exposure during the day is crucial for synchronizing circadian rhythms and promoting melatonin production at night, which is essential for sleep [8][9] - The intensity and timing of light exposure are critical; natural sunlight can be significantly brighter than typical household lighting, which is insufficient for regulating biological clocks [8] - Studies indicate that increased daytime light exposure correlates with better sleep quality, while inadequate light during the day and excessive light at night can shorten lifespan [9][10] Group 3: Meal Timing and Quality - Meal timing is closely linked to circadian rhythms; the body is more adapted to process calories during the day, and late-night eating can disrupt biological clocks and sleep [11] - The quality of food consumed also affects sleep; diets high in sugar and saturated fats can lead to poor sleep quality, while plant-based foods may improve sleep [12] - It is recommended to have dinner at least three hours before bedtime and to avoid snacking or sugary drinks afterward [11][12] Group 4: Sleep Timing and Consistency - Aligning sleep schedules with individual biological clocks is crucial for maximizing sleep benefits; irregular sleep patterns can lead to higher mortality risks [14] - Many individuals rely on alarms to wake up, indicating a misalignment with their natural circadian rhythms, which can lead to cumulative sleep deprivation [14] - Consistent sleep and meal times can help stabilize circadian rhythms, but flexibility is necessary for those with irregular schedules, such as shift workers [15]

Core Viewpoint - The introduction of "Good Night Milk" by Hema, which contains a low level of melatonin, has sparked discussions regarding its effectiveness and marketing claims related to sleep improvement [1][5][6]. Group 1: Product Details - Hema's "Good Night Milk" is produced by Beijing Sanyuan Foods Co., emphasizing "10 times+ native melatonin," with each 250ml bottle containing 12,500pg of melatonin, equivalent to 0.0000125mg [1][4]. - The product's melatonin content is significantly lower than the recommended dosage of 0.1mg-0.3mg for sleep improvement, raising concerns about its efficacy [4][5]. - Prior to Hema's launch, Sanyuan introduced "Ultimate Good Night Milk" on March 21, 2023, also claiming high melatonin content [6][8]. Group 2: Regulatory and Marketing Concerns - In China, melatonin is classified as a health food ingredient, requiring specific labeling, yet Hema's product states it "cannot replace health products" [5]. - Experts indicate that the evidence supporting melatonin's effectiveness for sleep improvement is insufficient, as it primarily aids those with melatonin deficiency or jet lag [5][6]. - Legal experts suggest that Hema's marketing does not explicitly claim sleep benefits, potentially avoiding false advertising allegations under food safety regulations [5][6]. Group 3: Company Performance and Market Context - Sanyuan has applied for a patent related to increasing melatonin content in milk, which was granted in September 2023, indicating a strategic focus on enhancing product offerings [8][12]. - Sanyuan's revenue has declined from a peak of 8.8 billion yuan in 2021 to an estimated 7 billion yuan in 2024, with a significant drop in its Beijing market revenue by 28.79% year-on-year [19].