Core Insights - Aimeike achieved a revenue of 1.865 billion yuan and a net profit of 1.093 billion yuan in the first three quarters of 2025 [1] - The company has a strong liquidity position with cash and cash equivalents of 1.18 billion yuan and trading financial assets of 1.973 billion yuan as of September 30, 2025 [1] - Aimeike's cash flow from operating activities for the first three quarters was 1.073 billion yuan, indicating robust cash generation capabilities [1] Financial Performance - Aimeike distributed cash dividends, profits, or interest payments totaling 1.513 billion yuan in the first three quarters [1] - Research and development expenses increased by 26.67% year-on-year to 237 million yuan, reflecting the company's commitment to innovation [1] - Other income reached 52.185 million yuan, and fair value changes contributed 64.307 million yuan to the financial results [2] Strategic Developments - The acquisition of a controlling stake in South Korea's REGENBiotech, Inc. resulted in a 233.54% increase in intangible assets compared to the previous year [2] - Fixed assets grew by 47.75% year-on-year, and non-current assets due within one year increased by 60.57%, primarily due to an increase in short-term financial products [2] - Aimeike's strategic initiatives include entering the hair regeneration market with the approval of Minoxidil topical solution and the registration of a new cosmetic ingredient, Glycyrrhetinic Acid A [1]

脂肪细胞 作为重要的能量储存库，会根据全身代谢需求储存或释放脂质。但它们能否通过局部代谢交流促进组织再生，目前仍不清楚。 2025 年 10 月 22 日，中国台湾学者在 Cell 子刊 Cell Metabolism 上发表了题为： Adipocyte lipolysis activates epithelial stem cells for hair regeneration through fatty acid metabolic signaling 的研究论文。 该研究表明，脂肪细胞脂解通过脂肪酸代谢信号，激活 上皮毛囊干细胞 ，促进毛发再生，而局部使用单不饱和脂肪酸，即可激活毛囊干细胞以促进毛发生长。 撰文丨王聪 编辑丨王多鱼 排版丨水成文 脂肪组织 作为许多器官的重要组成部分，是富含能量的脂质的主要储存库，同时还能提供关键的机械缓冲和保温保护。此外，它还是一种内分泌器官，分泌蛋白 质激素 （即脂肪因子） 来调节全身代谢。保持健康的脂肪组织对于整个机体的健康至关重要。肥胖症中常见的慢性全身性脂肪组织炎症会导致全身性炎症和代谢 失调。此外，慢性局部脂肪组织炎症，包括一系列异质性疾病，其特征是免疫细胞持 ...

Core Viewpoint - The company is actively advancing its medical laser business, specifically focusing on hair regeneration devices, and is in the process of obtaining necessary medical device registrations for market application [1] Group 1: Product Development - The company has developed a mid-infrared femtosecond laser hair growth device, which has completed product application testing and laboratory biological validation [1] - The company is working on obtaining Class III medical device registration for its hair regeneration-related products [1] Group 2: Market Strategy - The company plans to collaborate closely with major public hospitals, private medical aesthetic institutions, and chain hair transplant organizations to promote the market application of its products [1]

Core Viewpoint - The research conducted by Chen Ting's team reveals that the bioelectric signaling of fibroblasts plays a crucial role in hair regeneration, with hyperpolarization promoting hair growth and depolarization inhibiting it [3][4][5][7]. Group 1: Research Findings - The study identifies that chromatin changes link the KCNJ2 gene in patients with congenital generalized hypertrichosis to distal enhancers [5]. - Upregulation of KCNJ2 in fibroblasts, rather than other cell types, drives sustained hair growth [5]. - Hyperpolarization of fibroblast membranes promotes hair growth, while depolarization halts it [5]. - KCNJ2-mediated hyperpolarization can reverse hair loss associated with aging and androgenetic alopecia [5]. Group 2: Mechanism Insights - The research indicates that the membrane potential oscillation of fibroblasts is particularly associated with the anagen phase of the hair cycle, where hyperpolarization is crucial [4]. - Inducing depolarization in fibroblasts can delay the anagen phase, while hyperpolarization can rescue hair loss in aging and androgenetic alopecia models [4][5]. Group 3: Clinical Implications - The findings suggest a novel therapeutic approach for hair loss treatment by targeting the bioelectric properties of fibroblasts [7].