Core Viewpoint - Aiming to provide early cancer screening services, Wuhan Aimesen Life Technology Co., Ltd. has submitted its IPO application to the Hong Kong Stock Exchange, highlighting its innovative cancer detection products and significant market potential in China [1][2]. Company Overview - Founded in 2015, Aimesen specializes in early cancer detection, with a mission to become a "munitions depot" for tumor screening [1]. - The company has developed two core products: Aixin Gan for liver cancer and Aiguang Le for urinary tract cancer, utilizing advanced technologies for non-invasive testing [2]. Product Details - Aixin Gan is the world's first liver cancer detection reagent based on methylation and qPCR technology, achieving a sensitivity of 84.43% for stage I liver cancer [2]. - Aiguang Le allows for non-invasive detection of urinary tract cancer using just 1 milliliter of urine, enhancing efficiency and convenience [2]. - Aimesen has launched over 20 early screening products covering various cancers, including colorectal, liver, esophageal, and gastric cancers [4]. Market Context - In China, digestive system cancers account for 50% of cancer-related deaths, with colorectal cancer alone having 560,000 new cases annually and an early diagnosis rate below 20% [2]. - The early screening market for cancer in China is projected to grow from $18.4 billion in 2019 to $28.9 billion by 2030, with a compound annual growth rate of 4.2% [5]. Financial Performance - Aimesen reported revenues of 6.23 million yuan, 7.24 million yuan, and 6.51 million yuan for the first half of 2023, 2024, and 2025, respectively, with net losses of 67.92 million yuan, 38.63 million yuan, and 13.91 million yuan during the same periods [4]. - Research and development expenditures were 22.74 million yuan, 15 million yuan, and 4.52 million yuan for the same periods, while sales expenses were 25.17 million yuan, 15.10 million yuan, and 6.39 million yuan [4]. Customer Base - Aimesen's primary customers include testing laboratories, with the top three clients in 2024 being Wuhan Aino Medical Laboratory, KingMed Diagnostics, and Guangdong Capbio, contributing 52.1%, 9.3%, and 5.2% to total sales, respectively [5].

Core Viewpoint - Wuhan Aimeson Life Science Technology Co., Ltd. has submitted a listing application to the Hong Kong Stock Exchange, focusing on early cancer detection technologies with two core products targeting liver cancer and urinary tract cancer [1][2]. Group 1: Company Overview - The company was established in January 2015 and is a leading early cancer detection firm, concentrating on cancers with high incidence and mortality rates [1]. - Aimeson has developed the world's first methylation-based early cancer detection technology, with two main products: Aixin Gan for liver cancer and Aiguang Le for urinary tract cancer [1]. Group 2: Product Details - Aixin Gan, a liver cancer detection reagent, has a sensitivity of 92.33% and specificity of 93.35%, with a sensitivity of 84.43% for stage I patients [1]. - Aiguang Le allows non-invasive detection of urinary tract cancer using just 1 milliliter of urine, significantly improving efficiency and convenience compared to traditional methods [1][2]. - The company has additional products approved by the National Medical Products Administration (NMPA), including Aichang Kang and Aichang Jian for colorectal cancer, and Aisi Ning for esophageal cancer [2]. Group 3: Research and Development - The company's R&D expenditures for 2023, 2024, and the first half of 2025 were RMB 22.7 million, RMB 15.0 million, and RMB 4.5 million, respectively [3]. - The R&D costs for Aixin Gan and Aiguang Le were RMB 4.2 million, RMB 7.5 million, RMB 0.4 million and RMB 2.5 million, RMB 2.8 million, RMB 3.9 million, respectively, over the same periods [3]. - Aimeson has a strong internal R&D team of 28 members, primarily based in Wuhan, with 75% holding a bachelor's degree or higher [3]. Group 4: Funding Utilization - The funds raised from the listing will be allocated to the R&D, registration, and commercialization of core products Aixin Gan and Aiguang Le, as well as other pipeline products [3]. - The company aims to enhance its general R&D capabilities, improve production facility automation, and expand its product portfolio through potential acquisitions or licensing in the cancer detection field [3].