Core Insights - On May 28, 2025, a total of 23 papers were published in the prestigious journal Nature, with 13 authored by Chinese scholars, highlighting the significant contribution of Chinese researchers to global scientific advancements [1][3][5]. Group 1: Research Highlights - The research by Huang Xiaoqiang from Nanjing University focuses on electricity-driven enzymatic dynamic kinetic oxidation, achieving a breakthrough in the compatibility of traditional electrochemistry and enzyme catalysis, paving the way for asymmetric biosynthesis of phenylpropanoids like ibuprofen [1]. - Stephen Tang from Columbia University revealed a novel antiviral mechanism of the DRT9 reverse transcriptase family, demonstrating its role in synthesizing poly-dA to combat infections, thus expanding the understanding of bacterial immune systems [2]. - The study by professors Bao Xiaojun and Zhu Haibo from Fuzhou University, along with Ye Mao from the Dalian Institute of Chemical Physics, discusses platinum migration in zeolites for stable propane dehydrogenation catalysts, contributing to advancements in catalytic processes [3]. Group 2: Cancer Research - The research led by Academician Zhang Zemin from Peking University and Chongqing Medical University introduces the concept of "Cross-tissue Cellular Modules" (CM) and develops a computational framework (CoVarNet) to identify these modules, providing insights into multicellular coordination in cancer progression [4]. Group 3: Environmental Studies - A study by Zhang Liangpei and colleagues discusses the reduction of radiative forcing due to increased land albedo in the early 21st century, emphasizing the impact of land surface changes on climate dynamics [6]. - Research by Zheng Bo and Zhao Yuanhong examines how air pollution affects global methane budget trends and variability, highlighting the interplay between environmental factors and greenhouse gas emissions [7]. Group 4: Semiconductor Research - The work by Professor Pei Jian from Peking University presents a method for light-triggered regionally controlled n-doping of organic semiconductors, which could enhance the performance of electronic devices [8]. Group 5: Quantum Physics - The research by Guo Yanliang discusses the observation of anyonization of bosons in a quantum gas, contributing to the understanding of quantum states and their applications [9]. Group 6: Behavioral Science - The study by Andrew Wang from Yale University reveals that gut-derived T cells act as a communication link to the brain, influencing behavior through the subfornical organ, thus bridging immunology and neuroscience [11]. Group 7: Seasonal Dynamics - Research by Professor Long Di from Tsinghua University highlights the global dominance of seasonality in shaping lake-surface extent dynamics, providing insights into ecological changes driven by seasonal variations [12]. Group 8: Magnetism - The study by Qian Song from MIT explores the electrical switching of a p-wave magnet, which could have implications for future magnetic materials and technologies [13].

Core Viewpoint - The article discusses the revival of electrochemistry in synthetic chemistry, highlighting its potential in enzyme applications and the challenges faced in utilizing electrochemistry to unlock new catalytic modes for enzymes [2]. Group 1: Research Findings - A research team from Nanjing University published a paper in Nature on May 28, 2025, demonstrating a new catalytic function of ThDP-dependent enzymes through the integration of electrocatalysis and enzyme catalysis, achieving dynamic kinetic oxidation of aldehydes to chiral carboxylic acids [2]. - The study reported a robust electroenzymatic method for the efficient synthesis of ten (S)-arylpropionic acid anti-inflammatory drugs, such as ibuprofen and naproxen, with enantiomeric selectivity reaching 99% ee and enzyme loading as low as 0.05 mol% [4]. - Mechanistic studies revealed that the electroenzyme plays multiple roles in precise substrate recognition, accelerating racemization, and facilitating electron transfer events for kinetic matching [5]. Group 2: Recent Publications - The research team has published three papers in Nature over the past two years, including a study on December 18, 2023, that developed a dual catalytic system combining ThDP-dependent enzymes and photocatalysis, significantly expanding enzyme catalytic functions and providing new strategies for chiral precision control in chemical fields [7]. - Another publication on November 22, 2024, introduced a synergistic photobiocatalysis system for enantioselective triple radical sorting, overcoming the limitations of natural enzymes that typically catalyze only 1-2 substrates, thus empowering green biomanufacturing [10].