Core Viewpoint - The article discusses the revival of electrochemistry in synthetic chemistry, highlighting its potential in enzyme applications and the challenges faced in utilizing electrochemistry to unlock new catalytic modes for enzymes [2]. Group 1: Research Findings - A research team from Nanjing University published a paper in Nature on May 28, 2025, demonstrating a new catalytic function of ThDP-dependent enzymes through the integration of electrocatalysis and enzyme catalysis, achieving dynamic kinetic oxidation of aldehydes to chiral carboxylic acids [2]. - The study reported a robust electroenzymatic method for the efficient synthesis of ten (S)-arylpropionic acid anti-inflammatory drugs, such as ibuprofen and naproxen, with enantiomeric selectivity reaching 99% ee and enzyme loading as low as 0.05 mol% [4]. - Mechanistic studies revealed that the electroenzyme plays multiple roles in precise substrate recognition, accelerating racemization, and facilitating electron transfer events for kinetic matching [5]. Group 2: Recent Publications - The research team has published three papers in Nature over the past two years, including a study on December 18, 2023, that developed a dual catalytic system combining ThDP-dependent enzymes and photocatalysis, significantly expanding enzyme catalytic functions and providing new strategies for chiral precision control in chemical fields [7]. - Another publication on November 22, 2024, introduced a synergistic photobiocatalysis system for enantioselective triple radical sorting, overcoming the limitations of natural enzymes that typically catalyze only 1-2 substrates, thus empowering green biomanufacturing [10].

Core Viewpoint - The recent surge in mergers and acquisitions (M&A) in the A-share market reflects a deep-seated logic of industrial upgrading and strategic transformation, showcasing the diversification and specialization of the current M&A landscape [1] Group 1: Characteristics of Recent M&A Activity - Cash transactions dominate the current wave of M&A, with companies accelerating their entry into new sectors [2] - The M&A activities are driven by three strategic directions: seeking breakthroughs in technological innovation, enhancing risk resilience through resource integration, and capitalizing on policy incentives to enter emerging sectors like AI and semiconductors [2] Group 2: Industry Chain Integration - Industry chain integration is a core driver of M&A among A-share companies, with firms pursuing horizontal and vertical integration to enhance competitiveness [3] - Jiangsu Zongyi Co., Ltd. plans to acquire control of Jiangsu Jilai Microelectronics Co., Ltd. to extend its reach into the power semiconductor sector [3] - Suzhou Dongshan Precision Manufacturing Co., Ltd. intends to acquire 100% of Groupe Mécanique Découpage to optimize its debt structure and enhance its capabilities in the automotive parts sector [3][4] Group 3: Strategic Focus and Diversification - Companies are adopting divergent strategies, with some focusing on core businesses while others pursue diversification [5] - Jiangsu Zongyi's acquisition of Jilai Microelectronics aims to strengthen its position in the integrated circuit sector, enhancing its technical capabilities and market share [5] - China National Pharmaceutical Group plans to acquire Beijing Jinsui Technology to enter the e-commerce service sector, diversifying its business and revenue streams [5] Group 4: Investment Trends - Beijing Lier High-Temperature Materials Co., Ltd. is investing in Shanghai Zhenliang Intelligent Technology Co., Ltd. to enter the AI chip market, reflecting a commitment to both core business and new growth areas [6] Group 5: Valuation and Compliance Concerns - Valuation and compliance are critical issues in M&A transactions, directly impacting their success [8] - Huafeng Chemical Co., Ltd. terminated its planned acquisition of Zhejiang Huafeng Synthetic Resin Co., Ltd. due to high valuation and lack of shareholder approval, highlighting the risks associated with high-premium related transactions [8][9] - Companies are advised to establish a scientific valuation system and ensure transparency in operations to mitigate risks associated with related-party transactions [10]