梅斯医学 . 以下文章来源于梅斯医学 ，作者木白 梅斯医学（MedSci）是国内领先的医学科研与学术服务平台，致力于医疗质量的改进，为临床实践提 供智慧、精准的决策支持，让医生与患者受益。 本文来自微信公众号： 梅斯医学 ，编辑：木白，作者：木白，原文标题：《每一口外卖、瓶装水都 在伤害心脏和生育力！最新研究：微塑料不仅加剧动脉粥样硬化，还侵入男性生殖系统，不粘锅涂层 竟成「帮凶」》 忙碌的打工人们，在无数个赶时间的打工日，走进咖啡店打包一杯咖啡唤醒困倦的大脑，点一份外卖 解决一餐，又或是在口渴时拧开瓶装水，随手撕开包装袋吃点零食……然而，正是在这一杯一袋、一 撕一拧之间，一些肉眼看不见的「不速之客」就开始「兴风作浪」了。这些「不速之客」便是无处不 在的微塑料，是指直径在1μm到5mm之间的微小塑料碎片。 它们小到可以轻松穿过层层屏障和防线，混在水、食物，甚至空气中，最终进入血液，在体内「落 脚」。按照目前对人体暴露剂量的估算，每个人每年通过进食和呼吸进入体内的塑料颗粒，总数可能 高达7.4万到12.1万个。除了消化道和呼吸道，研究者甚至在脑、肝脏、胎盘和血管等多个重要组织 和器官内检测到它们的踪迹。 微塑料 ...

Core Viewpoint - The consumption of ultra-processed foods (UPF) is significantly increasing globally, which is linked to various negative health outcomes, particularly in male reproductive and metabolic health [2][4][10]. Group 1: Health Impacts of Ultra-Processed Foods - UPF consumption is associated with an increased risk of chronic diseases, including cardiovascular diseases, metabolic disorders, certain cancers, and mental health issues [2]. - A notable decline in male semen quality has been observed globally, with sperm counts decreasing by approximately 60% since the 1970s, potentially linked to the rise in UPF consumption [6]. - The recent study confirms that UPF negatively impacts male reproductive and cardiovascular metabolic health, regardless of caloric intake [4][10]. Group 2: Research Findings - The study utilized a controlled 2×2 crossover design to assess the effects of UPF on reproductive and metabolic health, indicating that the harmful effects of UPF are not solely due to increased caloric intake [6][8]. - Key hormonal levels involved in energy metabolism and sperm production, such as GDF15 and follicle-stimulating hormone (FSH), were found to be altered due to UPF consumption [7][8]. - There was a significant increase in serum levels of phthalates (cxMINP), which are endocrine disruptors, following UPF consumption, while lithium levels in plasma decreased, correlating with mood disorders and cognitive decline [7][8].