Summary of Edwards Lifesciences FY Conference Call (January 12, 2026) Company Overview - **Company**: Edwards Lifesciences (NYSE: EW) - **Industry**: Medical Technology (MedTech), specifically focusing on structural heart disease Core Points and Arguments 1. **Strategic Focus**: The company has concentrated on structural hearts over the past three years, deploying strategies across core platforms such as TAVR (Transcatheter Aortic Valve Replacement), TMTT (Transcatheter Mitral and Tricuspid Therapies), and surgical innovations, with a commitment to next-generation innovations [2][3][4] 2. **Market Opportunity**: There are over 20 million patients globally with unmet needs in structural heart disease, representing significant growth potential for the company [4] 3. **Innovation Commitment**: Edwards aims to pioneer therapies for patient groups currently without solutions, including those with asymptomatic aortic stenosis (AS), mitral disease, tricuspid disease, and aortic regurgitation [3][4] 4. **Product Development**: The company has launched two world-first catheter-based replacement valves for mitral and tricuspid conditions and continues to invest over $1 billion in R&D while achieving profitable growth [9] 5. **Financial Performance**: The company is on track to meet its sales guidance of 8-10% and exceed EPS guidance for 2025, with expectations for continued strong performance in 2026 [9][14] Growth Outlook 1. **Revenue Projections**: Edwards anticipates achieving $2 billion in revenue from TMTT by 2030, with overall sales growth projected at 8-10% and EPS growth of approximately 15% in 2026 [6][14] 2. **Market Dynamics**: The TAVR market is stabilizing and showing signs of acceleration, with a shift from a four-competitor to a three-competitor market, allowing Edwards to gain market share [18][20] 3. **Regulatory Developments**: The reopening of the U.S. National Coverage Determination (NCD) for TAVR is expected to improve patient access to this technology, potentially enhancing market volumes [11][24] Product and Technology Insights 1. **TAVR Innovations**: The SAPIEN platform is highlighted as the best-in-class technology, with recent studies proving its durability and effectiveness for asymptomatic patients [5][18] 2. **TMTT Portfolio**: The company has a comprehensive portfolio including PASCAL, EVOQUE, and SAPIEN M3, which are designed to provide personalized care [6][10] 3. **Emerging Therapies**: Edwards is developing new therapies for patients with limited options, such as TAVR for moderate AS and transcatheter therapies for heart failure [8][11] Financial Strategy and Capital Allocation 1. **Investment Focus**: The company prioritizes funding innovation and production capacity, with a commitment to maintaining high levels of R&D investment while improving operational efficiency [33][35] 2. **M&A Activity**: While M&A remains a priority, the company emphasizes internal innovation and early-stage investments over acquisitions [34][35] 3. **Share Repurchase**: Edwards plans to continue share repurchase programs to offset dilution and enhance shareholder value [34] Additional Insights 1. **Patient-Centric Approach**: The company emphasizes a patient-focused culture, with over 16,000 employees dedicated to improving patient care globally [4][5] 2. **Long-Term Vision**: Edwards aims to sustain double-digit growth and maintain its position as a pioneer in the MedTech industry, focusing on long-term innovation and market leadership [17][15] This summary encapsulates the key points discussed during the conference call, highlighting Edwards Lifesciences' strategic direction, market opportunities, product innovations, and financial outlook.

Core Viewpoint - The company, HeartLink Medical-B (02160.HK), has announced significant growth in its VitaFow® series of transcatheter aortic valves and delivery systems (TAVI), with a cumulative implantation of nearly 1,300 cases across 35 countries and regions as of the announcement date [1] Group 1: Market Expansion - The projected implantation volume for 2025 is expected to exceed 850 cases, representing an increase of nearly 350% compared to 2024 [1] - In the second half of 2025, the implantation volume is anticipated to grow by over 170% compared to the first half, driven by the commercialization of VitaFowLiberty® following CE mark approval in European countries and continued market share growth in emerging markets in Asia and Latin America [1] Group 2: Strategic Enhancements - The company's board believes that the recent acquisition of Micro-Invasive Cardiac Management will strengthen local channel resources and clinical support systems in mature markets like Europe, significantly improving market access efficiency for TAVI products [1] - The company aims to continuously leverage the synergies from business integration, advance the research and clinical progress of next-generation TAVI products, and enhance its overall competitiveness in the global valve treatment sector [1]

Core Viewpoint - MicroPort CardioFlow-B (02160) has announced significant growth in its VitaFow series transcatheter aortic valves and delivery systems, with a global presence in 35 countries and nearly 1,300 implants to date [1] Group 1: Market Expansion - The company expects to exceed 850 implants in 2025, representing a nearly 350% increase compared to 2024 [1] - In the second half of 2025, the implant volume is projected to grow by over 170% compared to the first half, driven by the commercialization of VitaFow Liberty in Europe following CE certification and increased market share in emerging markets in Asia and Latin America [1] Group 2: Strategic Development - The board believes that the recent acquisition of MicroPort Cardiac Rhythm Management will enhance local channel resources and clinical support systems in mature markets like Europe, significantly improving market access efficiency for TAVI products [1] - The company aims to continuously leverage the synergies from business integration, advancing the research and clinical progress of next-generation TAVI products, and enhancing its comprehensive competitiveness in the global valve treatment sector [1]

Summary of Edwards Lifesciences 2025 Investor Day Company Overview - **Company**: Edwards Lifesciences (NYSE: EW) - **Focus**: Structural heart disease, particularly in areas such as TAVR (Transcatheter Aortic Valve Replacement), mitral, and tricuspid valve therapies [1][3][12] Key Industry Insights - **Market Opportunity**: Structural heart disease represents a significant and growing market with millions of patients in need. The company aims to address large unmet patient needs through innovative therapies [4][16] - **Patient Burden**: Structural heart disease is the leading cause of hospitalization among middle-aged populations, creating a substantial burden on healthcare systems [19][22] Core Company Strategies - **Innovation Strategy**: Edwards focuses on breakthrough innovations to create and define new therapeutic categories, such as TAVR and tricuspid replacement [3][5] - **Long-term Commitment**: The company has a history of investing in innovation, with over $1 billion internally and $1.6 billion externally in structural heart disease [9][10] - **Diversified Growth Drivers**: The company has identified three primary growth drivers: TAVR, mitral, and tricuspid therapies, along with emerging opportunities in structural heart failure and aortic regurgitation [12][15] Financial Performance and Projections - **Sales Growth Guidance**: For 2025, the company expects total sales growth between 8% and 10%, with TAVR growth projected at 5% to 7% and TMTT (Transcatheter Mitral and Tricuspid Therapies) expected to grow by 50% to 60% [12][15] - **Earnings Per Share (EPS)**: Projected EPS for 2025 is between $2.40 and $2.50, setting a strong base for double-digit earnings growth in 2026 and beyond [12] Product Innovations and Pipeline - **TAVR Innovations**: The EARLY TAVR trial results indicate a shift in treatment paradigms, suggesting that patients with severe aortic stenosis should not wait for symptoms before treatment [30][45] - **Emerging Technologies**: The company is pursuing new technologies for aortic regurgitation, including the acquisition of J-Valve and JenaValve, which are expected to enhance treatment options [65] Clinical Insights - **Patient Management**: The company emphasizes the importance of timely intervention for patients with structural heart disease, advocating for a shift in clinical guidelines to treat patients based on disease severity rather than symptoms [57][63] - **Evidence Generation**: Edwards has a strong focus on generating clinical evidence to support its therapies, with over 10,000 patents and numerous FDA-approved studies [7][41] Challenges and Considerations - **Market Dynamics**: The company acknowledges challenges such as the slowing growth of TAVR and the need to expand treatment capacity in healthcare systems [38][39] - **Regulatory Changes**: Anticipated changes in guidelines and coverage determinations are expected to impact treatment pathways and patient access to therapies [62][63] Conclusion - **Long-term Vision**: Edwards Lifesciences is positioned for sustainable, long-term growth through its innovative product pipeline and commitment to addressing the needs of patients with structural heart disease [16][12]

Investment Rating - The report maintains a "Buy" rating for the company, indicating a positive outlook for its stock performance relative to the market index [2][6]. Core Insights - The company has demonstrated impressive year-on-year growth, with a revenue increase of 30.58% and a net profit growth of 57.93% for the first three quarters of 2025 [5][6]. - The structural heart disease segment has seen significant revenue growth, particularly from the artificial biological heart valve, which increased by 89.83% year-on-year [5]. - The company is actively pursuing the registration of 12 products, with 8 already in the review phase, indicating strong future growth potential [5][6]. - The development of innovative products, such as the modular interventional valve, is progressing well and is expected to provide comprehensive treatment options for patients [5]. Financial Performance Summary - For the first three quarters of 2025, the company reported revenues of 382 million yuan and a net profit of 93 million yuan [5]. - The projected revenues for 2025, 2026, and 2027 are 698.40 million yuan, 1,014.55 million yuan, and 1,349.32 million yuan, respectively, with corresponding net profits of 245.22 million yuan, 406.44 million yuan, and 555.12 million yuan [7][12]. - The earnings per share (EPS) are expected to grow from 1.78 yuan in 2025 to 4.03 yuan in 2027, reflecting strong profitability growth [6][12]. Market Position and Growth Drivers - The company is expected to continue increasing its market share in traditional product areas, driven by the rising incidence of structural heart diseases and the expanding indications for transcatheter aortic valve replacement (TAVR) procedures [6]. - The anticipated growth in the heart surgery demand and the expansion of the patient population eligible for secondary valve replacement are key factors supporting the company's growth trajectory [6].

Core Viewpoint - The company reported strong financial performance in H1 2025, with significant revenue and profit growth, driven by successful product launches and effective cost management [1][2]. Financial Performance - In H1 2025, the company achieved revenue of 248 million yuan, a year-on-year increase of 30.07% [1] - The net profit attributable to shareholders reached 71 million yuan, reflecting a substantial year-on-year growth of 102.90% [2] - Q2 2025 saw revenue of 148 million yuan, up 29.25% year-on-year and 47.68% quarter-on-quarter [1] - Q2 2025 net profit was 39 million yuan, a year-on-year increase of 44.75% and a quarter-on-quarter increase of 19.67% [1] Gross Margin and Cost Management - The company's gross margin for H1 2025 was 88.71%, a slight decrease of 0.82 percentage points year-on-year [1] - Q2 2025 gross margin improved to 90.54%, an increase of 1.07 percentage points year-on-year and 4.54 percentage points quarter-on-quarter [1] - The company effectively controlled costs through digitalization and strong cost management, contributing to improved gross margins [1] R&D and Product Development - The company maintained high R&D investment, with R&D expense ratio decreasing significantly due to revenue growth [2] - As of H1 2025, the company had 22 approved Class III medical devices, with 11 filling domestic market gaps [3] - 12 additional Class III medical device registration applications are expected in 2025, indicating a robust product pipeline [3] Market Position and Product Launches - The heart valve segment saw an 88.96% year-on-year increase in sales, with the TAVR product gaining significant market share [2] - The company received registration approval for TAVR in Indonesia and patent authorization in Japan [2] - The company is set to commercialize its unique "valve-in-valve" product in Q3 2025, which is expected to boost sales [4] Future Outlook - Revenue projections for 2025-2027 are set at 698 million, 1.015 billion, and 1.349 billion yuan, respectively, with net profits of 245 million, 406 million, and 555 million yuan [5] - The company is expected to benefit from increasing heart disease prevalence and expanding TAVR indications to lower-risk groups [5]

Group 1 - The company reported a total revenue of RMB 25.5 million for the six months ending June 30, 2025, with a primary revenue of RMB 13.4 million and other income of RMB 12.1 million [1] - The adjusted loss for the period was RMB 91.8 million, a decrease of RMB 2.4 million compared to the previous year's loss of RMB 94.2 million, attributed to revenue growth and improved operational efficiency [1] - Research and development expenses increased from RMB 82.2 million in the previous year to RMB 88.9 million during the reporting period, primarily due to a rise in share-based payment expenses from RMB 11.7 million to RMB 36.2 million [1] Group 2 - The company's vision is to become a high-potential medical device enterprise with a global perspective, providing innovative products for the treatment of structural heart diseases [2] - The company plans to accelerate the global business layout and progress of the LuX-Valve product series, aiming to become a benchmark in the transcatheter tricuspid valve replacement field [2] - The company aims to enhance operational efficiency, accelerate revenue and profit growth, and continuously innovate to achieve sustainable development of its long-term international strategy [2]

Core Insights - The article highlights the recent acquisition by Heart通医疗 of the remaining 49% stake in Shanghai Zhaoxin, making it a wholly-owned subsidiary, with a total acquisition cost of RMB 170 million [1][2]. Company Overview - Heart通医疗, established in 2009 and officially registered in 2015, focuses on innovative medical devices for structural heart diseases, with its headquarters in Shanghai and listed on the Hong Kong Stock Exchange in 2021 [2]. - The company emphasizes research and innovation, developing a comprehensive range of transcatheter and surgical solutions for structural heart diseases, including products for transcatheter aortic valve implantation (TAVI) [2]. Market Performance - Shanghai Zhaoxin specializes in left atrial appendage-related medical devices, with its core product, the AnchorMan left atrial appendage occlusion system, receiving NMPA approval for market entry in January 2024 [5][6]. - The TAVI series products of Heart通医疗 are already in over 650 hospitals across China, and the company has expanded its international presence to nearly a hundred hospitals in countries like Argentina, Colombia, and Switzerland [4]. Product Development - The AnchorMan left atrial appendage occlusion system has shown promising clinical results, achieving a 98.1% clinical success rate and a 100% left atrial appendage occlusion success rate in a one-year follow-up study [7].

报名：首届全球眼科大会 | 议程更新 报名：首届全球骨科大会 | 议程更新 报名：首届全球心血管大会 | 奖项申报 合作伙伴征集：2025全球手术机器人大会 心未来 2025年3月30日， 心通医疗 发布截至2024年12月31日止年度业绩公告。 # 财报数据 # 关于心通 医疗 2024年公司实现收入 3.62亿 元，同比增长 7.5% ，收入增长主要得益于 二代主瓣产品及主动脉瓣膜球囊 在全球市场的持续商业化，特别是TAVI产品在海外市场的收入快速增长。 此外，子公司佐心医疗的左 心耳封堵器在中国正式商业化，为集团带来新的收入贡献。分地区来看，公司24年国内收入3.38亿元， 同比增长4.0%；海外地区实现收入0.24亿元，同比增长108.3%。经计算，公司H2实现收入1.38亿元，同 比下降13.4%。 公司24年实现毛利率 69.5% ，同比增加 1.1 pct ， 主要得益于公司采取的有效降本控费措施，以及业务 增长带来的规模效应。 公司24年归母净利润亏损 0.49亿 元，同比亏损收窄 89.5% ， 亏损大幅收窄主要得益于：收入增长、生 产成本下降及毛利率提升；公司通过统筹内外部资源、发挥集中效 ...