Group 1 - Barclays Bank is the largest holder of the newly listed Hong Kong innovative drug ETF, holding 20 million shares, which accounts for 4.5997% of the total fund shares [2][3] - The innovative drug sector has seen a significant rebound since the end of 2024, with the Hang Seng Innovative Drug Index rising nearly 68% year-to-date as of July 2 [7] - The recent policy measures from the National Healthcare Security Administration and the National Health Commission aim to support the high-quality development of innovative drugs, proposing 16 measures to enhance R&D support and improve market accessibility [7][8] Group 2 - In the past, Barclays also held a significant position in the Huatai-PineBridge Hang Seng Innovative Drug ETF, owning 85 million shares, which represented 42.02% of the total shares, with a return of over 56% since its inception [4][2] - Recent trends show that the top holders of other innovative drug ETFs are primarily brokerages, private equity, individual investors, and corporate pension plans, indicating a diverse investor base [5] - The innovative drug industry in China is at a critical turning point, with a focus on ADC and dual-antibody technologies, which are expected to capture significant market share in global immunotherapy [8]

Core Viewpoint - Barclays Bank has become the largest holder of two Hong Kong-listed innovative drug ETFs, indicating a strategic investment in the innovative drug sector in Hong Kong [2][3]. Group 1: Investment Activity - As of June 30, Barclays Bank held 20 million shares of the Hua Bao Hang Seng Hong Kong Stock Connect Innovative Drug Select ETF, accounting for 4.5997% of the total fund shares, making it the largest holder [4]. - Previously, Barclays held 85 million shares of the Huatai-PineBridge Hang Seng Innovative Drug ETF (QDII) at the end of 2024, representing 42.02% of the total shares, also ranking as the largest holder [6][7]. Group 2: Market Performance - The innovative drug sector has seen a significant rebound since the end of 2024, with a notable increase over the past six months [5]. - As of July 2, the Hang Seng Innovative Drug Index has risen nearly 68% year-to-date, reflecting strong market performance [10]. Group 3: Policy Support - Recent favorable policies from the National Healthcare Security Administration and the National Health Commission aim to support the high-quality development of innovative drugs, proposing 16 measures to enhance R&D support, inclusion in insurance directories, and improve payment capabilities [10]. - Analysts believe that these policies demonstrate the government's commitment to fostering a high-quality development environment for innovative drugs, which could expand market opportunities [10]. Group 4: Future Outlook - The innovative drug industry in China may be at a critical turning point, with ADC and dual-antibody technologies expected to capture significant market share in global immunotherapy [11]. - Investment focus is shifting towards second-generation immuno-oncology drugs, metabolic diseases, and companies with strong clinical data and international capabilities [11].