有机构分析指出，目前，创新药指数已经自高点回调20%左右，部分创新药公司回调幅度达到 30%-50%，市场预期从八、九月份的过分乐观，切换至目前的偏悲观状态，而很多创新药公司的估值也 已经回归合理甚至低估的水平。站在当前时点，我们有理由对创新药板块重新乐观起来——中国创新药 企业正在重塑全球创新药研发生态体系，背靠强大的产业趋势，创新药行情虽有波折，但总会螺旋上 升。 把握创新药深度回调机遇，配置工具首选同类最大港股通创新药ETF（520880）及其场外联接基金 （025221），标的指数恒生港股通创新药精选指数具备三大独特优势： 1、纯粹，全面。不含CXO，纯正创新药！全面覆盖创新药研发类公司。 2、龙头占比大。前十大创新药龙头权重超71%，表征创新药硬核力量。 3、风险更可控。对流动性较差的成份股强制降权，有力管控尾部风险。 | | | 港股通创新药ETF (520880) 标的指数 | | | --- | --- | --- | --- | | | | 前十成份股权重高达71.51%,龙头优势显著 | | | 代码 | 简称 | 权重(%) | 总市值(亿港元) | | 6160.HK | 百济神州 | ...

方正证券表示，当下时点更应积极看多，新一轮行情有别于今年第一轮估值修复的轰轰烈烈行情，未来 创新药将呈现核心龙头震荡上行，新机会继续涌现的慢牛行情。 恒生医药ETF（159892）聚焦创新+药品主线，涵盖创新药、CXO、互联网药店等细分领域，具备较强 的创新特征，契合创新、出海等主线方向。 百济神州的三季报相当于给创新药行情注入了稳定剂，提示中国原研新药可以在国际市场获得丰厚的回 报和利润，打开创新药行情空间。 方正证券表示，本轮创新药从8月中下旬进行调整状态，部分个股尤其是港股调整剧烈，市场对创新药 的核心逻辑出现怀疑，部分市场资金在国际博弈扰动下有减仓，但实质上创新药BD的逻辑从未改变。 从后续一二级层出不穷的BD可以印证，部分个股调整剧烈是预期过高、过于超前导致，不是行情逻辑 的证伪或终结，这点从龙头稳健的走势上可见一斑。 ...

Group 1 - The Hong Kong stock market for innovative drugs experienced a significant surge, with the Hong Kong Stock Connect Innovative Drug ETF (520880) rising by 5.31%, outperforming the Hang Seng Index and other related indices [1] - Major stocks leading the rally included 3SBio, which surged by 10.18%, and BeiGene, which rose by 7.71%, reaching a nearly four-year high [1] - The ETF recorded a trading volume of 588 million yuan, indicating strong investor interest [1] Group 2 - Technical indicators show a strong bullish signal for the Hong Kong Stock Connect Innovative Drug ETF, with a significant increase in buying pressure and a MACD indicator suggesting a trend reversal [2] - Citic Securities forecasts continued over-allocation to the pharmaceutical sector through 2026, while Dongwu Securities identifies innovative drugs as a key investment theme for the same period [3] Group 3 - BeiGene's impressive performance, with a net profit of 1.139 billion yuan in the first three quarters, has positively influenced industry expectations [4] - The introduction of a new payment channel for high-priced innovative drugs through commercial insurance in the 2025 national medical insurance negotiations is expected to enhance cash flow for pharmaceutical companies [4] - The total value of outbound licensing transactions for Chinese innovative drugs exceeded 100 billion USD in the first ten months of 2025, highlighting the global competitiveness of Chinese pharmaceutical companies [4] Group 4 - The Hong Kong Stock Connect Innovative Drug ETF (520880) is recommended for investment, with its index comprising primarily innovative drug companies, excluding CXO firms [4][5] - The top ten innovative drug companies account for over 71% of the ETF's weight, indicating a strong focus on leading firms in the sector [5] - The ETF's design includes measures to control risks associated with less liquid stocks, enhancing overall risk management [6]

Core Viewpoint - The innovative drug sector in Hong Kong is experiencing a resurgence, with significant trading activity and price increases among leading companies, indicating a potential investment opportunity in this market [1][3]. Market Performance - The Hong Kong Stock Connect innovative drug ETF (520880) has seen a stable increase of over 2.5%, with trading volume exceeding 520 million yuan, a 130% increase compared to the previous day [1]. - Leading innovative drug stocks such as BeiGene have reached a three-year high with an 8.8% increase, while other companies like 3SBio and Kelun-Bio have also shown strong performance with gains exceeding 5% and 4% respectively [1][3]. Industry Trends - The acquisition of Metsera by Pfizer highlights the intensifying competition among multinational corporations for innovative drug pipelines [3]. - The upcoming release of the first commercial insurance innovative drug directory in early December is expected to provide a new growth engine for the innovative drug sector [3]. Company Performance - BeiGene recently reported impressive earnings, and CanSino Biologics announced significant results from its HARMONi-A study, reinforcing the positive trends in the industry [3]. - The ETF manager, Feng Chen Cheng, noted that the end of the year is typically a peak season for mergers and acquisitions in the biopharmaceutical sector, with the JPMorgan Healthcare Conference in early January serving as a catalyst for further developments [3]. Investment Strategy - The recommended investment approach is to actively accumulate shares in the Hong Kong Stock Connect innovative drug ETF (520880) and its associated funds, which track the Hang Seng Hong Kong Stock Connect Innovative Drug Select Index [3][4]. - The index is characterized by three unique advantages: it exclusively includes innovative drug companies, has a high concentration of leading firms, and employs measures to control risks associated with less liquid stocks [4][5]. Index Composition - The top ten holdings in the ETF account for over 71% of the index, showcasing the dominance of leading innovative drug companies [5][6]. - The ETF has surpassed a fund size of 2 billion yuan and has the highest liquidity among similar ETFs since its inception [6].

Group 1 - The Hong Kong innovative drug sector is experiencing a rebound after a two-month pullback, with the Hong Kong Stock Connect Innovative Drug ETF (520880) rising over 3% and quickly surpassing the 20-day moving average [1] - Significant capital has been flowing into the Hong Kong innovative drug sector, with the fund size of the Hong Kong Stock Connect Innovative Drug ETF (520880) exceeding 2 billion yuan for the first time on November 3, marking a 392% increase since its launch on July 7 [1] - The fund manager of the Hong Kong Stock Connect Innovative Drug ETF (520880) indicated that the innovative drug market may be on the verge of a rally, suggesting that the current period may be a high-probability zone for investment [1] Group 2 - Huafu Securities believes that the focus of the innovative drug market is shifting from broad valuation recovery to the ability of companies to deliver on their fundamentals, with companies that have excellent clinical data, strong commercialization capabilities, and successful international expansion potential likely to emerge as future winners [2] - The Hong Kong Stock Connect Innovative Drug ETF (520880) and its linked fund (025221) passively track the Hang Seng Hong Kong Stock Connect Innovative Drug Select Index, which exclusively invests in innovative drug R&D companies, with over 70% of its holdings in large-cap innovative drug leaders [2] - As of the end of September, the Hang Seng Hong Kong Stock Connect Innovative Drug Select Index has shown a year-to-date increase of 108.14%, outperforming other innovative drug indices [2]

Group 1: Market Trends - The chemical sector experienced a counter-trend rise on November 7, with related ETFs showing significant gains [1][4] - Multiple chemical and new materials ETFs saw increases of over 3% on November 7, while several new energy ETFs rose by more than 2% [4][5] - The Hong Kong biotech sector faced declines, with leading pharmaceutical stocks dropping over 3% [7] Group 2: ETF Performance - Several Hong Kong stock ETFs saw substantial net inflows recently, particularly in the Hang Seng Technology and Hong Kong innovative drug sectors [2][8] - The A500 ETFs showed high trading activity, with four funds exceeding 20 billion yuan in scale, led by Huatai-PB's A500 ETF at 26.463 billion yuan [6][7] - Overall, nearly 20 billion yuan flowed into ETFs, with significant investments in sectors like securities, banking, and electric grid equipment [10] Group 3: Innovation Drug Sector Outlook - The Hong Kong innovative drug index has dropped over 18% since its peak in September, but many institutions believe the sector may soon rebound [3][11] - Fund managers suggest that the current market conditions present a high-probability zone for long-term investments in the biopharmaceutical sector, recommending balanced allocations across various sub-sectors [11][12] - Upcoming international conferences and positive corporate earnings are expected to act as catalysts for the innovative drug sector [12]

Core Viewpoint - Significant capital is being invested in innovative drugs, with the Hong Kong Stock Connect Innovative Drug ETF (520880) experiencing strong buying momentum and a premium trading rate exceeding 0.6% as of November 4 [1] Group 1: Market Activity - The Hong Kong Stock Connect Innovative Drug ETF (520880) has attracted nearly 220 million yuan in the last 10 days as of November 3, indicating robust investor interest [1] - The ETF manager, Feng Chen Cheng, suggests that the innovative drug market may soon see a resurgence due to improved geopolitical conditions between China and the U.S. following a recent meeting between leaders [1] - The recent quarterly reports from companies like Innovent Biologics and Hengrui Medicine have confirmed strong performance in the innovative drug sector, further boosting investor confidence [1] Group 2: Policy and Industry Outlook - The policy environment remains supportive of innovative drugs, with recent information from medical insurance negotiations indicating continued favorable conditions for original innovations [1] - Huafu Securities notes that the focus of the innovative drug market is shifting from broad valuation recovery to the fundamental performance of companies, emphasizing the importance of clinical data, commercialization capabilities, and international expansion potential [1] Group 3: ETF Performance - The Hong Kong Stock Connect Innovative Drug ETF (520880) passively tracks the Hang Seng Hong Kong Stock Connect Innovative Drug Select Index, which exclusively includes innovative drug R&D companies and has a high concentration in large-cap leaders [2] - As of September 30, the index has seen a year-to-date increase of 108.14%, outperforming other innovative drug indices [2] - The ETF has reached a record fund size of over 2 billion yuan as of November 3, with an average daily trading volume of 474 million yuan, making it the largest and most liquid ETF in its category [2]

Core Viewpoint - The innovative drug sector is experiencing a significant rebound, with the Hong Kong Stock Connect Innovative Drug ETF (520880) showing strong performance and increased trading volume, indicating robust investor interest [1][2]. Group 1: Market Performance - The Hong Kong Stock Connect Innovative Drug ETF (520880) saw a V-shaped reversal, rising by 3% in the morning and peaking at 3.37% in the afternoon, ultimately closing up by 2.13%, outperforming all other pharmaceutical ETFs in the market [1]. - The ETF recorded a trading volume of 8.66 billion yuan, the highest since September 12, and has seen two consecutive days of increased volume [1]. - Out of the 37 innovative drug companies covered by the ETF, 33 stocks closed in the green, with notable gains from companies like First Signal Pharmaceuticals (+7.36%) and Innovent Biologics (+4.32%) [1]. Group 2: Policy and Industry Developments - The introduction of a "commercial insurance innovative drug catalog" mechanism in the 2025 national medical insurance negotiations is expected to benefit the sector, along with the anticipated breakthrough in pricing negotiations for CAR-T therapies [1]. - At the ESMO 2025 conference, domestic innovative drug companies had 35 research projects selected for oral presentations, setting a new record [1]. - A significant collaboration was announced between Innovent Biologics and Takeda, with a total scale of up to 11.4 billion USD, highlighting the growing partnerships in the industry [1]. Group 3: Future Outlook - The fund manager of the Hong Kong Stock Connect Innovative Drug ETF (520880) emphasized that the innovative drug market could see another surge, suggesting that the current period may represent a high-probability zone for medium to long-term investments in innovative drugs [2]. - The market is expected to transition from a funding-driven phase to a fundamental-driven phase, with a focus on quality factors, potentially favoring leading companies [2]. - The ETF is designed to track the Hang Seng Hong Kong Stock Connect Innovative Drug Select Index, which exclusively includes innovative drug development companies, with over 70% of its holdings in large-cap leaders [2].

Group 1 - The Hong Kong Stock Connect innovative drug sector experienced a significant rebound on November 3, with the innovative drug ETF (520880) showing a volatility of over 4.4% and a trading volume exceeding 500 million yuan, indicating strong bullish sentiment [1] - Key stocks such as Kangfang Biotech, Xiansheng Pharmaceutical, and Kangnuo Ya-B saw increases of nearly 6%, while other companies like Yuanda Pharmaceutical and Rongchang Biotech also experienced substantial gains [1] - The National Medical Insurance negotiation, which began on October 30, is expected to conclude with results announced in early December, introducing a new "commercial insurance innovative drug catalog" mechanism for the first time [1] Group 2 - Fund manager Feng Chen indicated that the innovative drug market could see a resurgence, suggesting that now may be a high-probability period for medium to long-term investments in innovative drugs [2] - The recent meeting between US and Chinese leaders has alleviated previous risks that suppressed the sector's performance, potentially allowing previously withdrawn funds to re-enter the market [2] - The current earnings season has shown strong performance from companies like Innovent Biologics and Hengrui Medicine, boosting confidence in the sector [2] Group 3 - The Hong Kong Stock Connect innovative drug ETF (520880) passively tracks the Hang Seng Hong Kong Stock Connect Innovative Drug Select Index, which focuses entirely on innovative drug R&D companies, with over 70% of its holdings in large-cap innovative drug leaders [3] - As of the end of September, the index has seen a year-to-date increase of 108.14%, outperforming other innovative drug indices [3] - The ETF has a fund size of 1.806 billion yuan and an average daily trading volume of 493 million yuan, making it the largest and most liquid ETF tracking this index [3]

Core Viewpoint - The innovative drug sector experienced a significant surge on October 31, with notable performances in both A-shares and Hong Kong stocks, driven by the initiation of the 2025 national medical insurance negotiations and the introduction of a "commercial insurance innovative drug catalog" mechanism [1][3]. Market Performance - The drug ETF (562050) in A-shares rose by 2.46%, while the Hong Kong innovative drug ETF (520880) surged by 5.25%, indicating high elasticity in the sector [1]. - Major stocks such as Sanofi and InnoCare Pharmaceuticals saw gains of 11% [1]. Policy Impact - The introduction of the "commercial insurance innovative drug catalog" is expected to alleviate the payment pressure for high-value innovative drugs, providing a supportive policy environment for the sector [1][3]. Technical Analysis - The Hong Kong innovative drug ETF (520880) showed strong technical indicators, including a significant increase in trading volume and a bullish reversal pattern, suggesting a potential trend change [1]. - The MACD indicator also indicated a reduction in bearish momentum, signaling a possible shift towards bullish sentiment [1]. Fund Manager Insights - The fund manager of the Hong Kong innovative drug ETF (520880) expressed optimism about the sector, citing the recent U.S.-China summit as a factor that may reduce risk factors previously affecting the sector [3]. - The current earnings season, with strong performances from companies like Innovent Biologics and Hengrui Medicine, is expected to boost confidence in the sector [3]. ETF Composition - The Hong Kong innovative drug ETF (520880) tracks the Hang Seng Hong Kong Stock Connect Innovative Drug Select Index, which focuses entirely on innovative drug development companies, with over 70% of its holdings in large-cap leaders [4][5]. - The top ten holdings account for 71.63% of the index, highlighting the dominance of leading companies in the sector [4]. Performance Metrics - As of September 30, the Hang Seng Hong Kong Stock Connect Innovative Drug Select Index has seen a year-to-date increase of 108.14%, outperforming other innovative drug indices [5]. - The Hong Kong innovative drug ETF (520880) has a fund size of 1.806 billion and an average daily trading volume of 493 million since its inception, making it the largest and most liquid ETF in its category [5].