Core Insights - The article highlights the ongoing development and innovation in the synthetic biology and biomanufacturing sectors in China, with a focus on Guangdong province, particularly Guangzhou and Shenzhen, which are leading in policy support and innovation outcomes [2][3]. Summary by Sections Industry Overview - Guangdong province's biomanufacturing industry is valued at approximately 1.3 trillion yuan, ranking third nationally, with plans to elevate the industry to a trillion-yuan scale through the "Action Plan for Accelerating the Construction of Biomanufacturing Industry Innovation High Ground" [2]. - Shenzhen has positioned synthetic biology as one of its "20+8" future industries, establishing a comprehensive support system for biomanufacturing, including a major synthetic biology infrastructure and a national innovation center [2]. Company Rankings - SynBioCon has released the "Top 500 Representative Enterprises in Biomanufacturing (Guangdong Edition)," featuring 76 companies recognized for their competitiveness based on team, core products, and diverse possibilities [3]. Upcoming Events - The "China Biomanufacturing Industry Map (2025)" will be published in August 2025, with a focus on 500 representative enterprises in biomanufacturing [1]. - The Fourth Synthetic Biology and Green Biomanufacturing Conference will be held from August 20-22, 2025, in Ningbo, Zhejiang, focusing on AI and biomanufacturing, green chemicals, new materials, future food, and agriculture [12][14].

Core Viewpoint - Tianjin Hesheng Biotechnology Co., Ltd. has completed a multi-million Pre-A round financing, which will accelerate its technological innovation in the synthetic biology field and lead new trends in health and nutrition solutions [1][2]. Group 1: Company Overview - Established in August 2023, Hesheng Biotechnology is a key technology transfer enterprise of Nankai University, gathering a leading research team in synthetic biology with nearly 30 years of experience [2]. - The company has developed a "DBTL" (Design-Build-Test-Learn) technical platform, utilizing proprietary gene element databases and self-developed AI algorithms to create high-productivity microbial strains [2]. - Hesheng Biotechnology has a comprehensive technical coverage from product research and development to downstream applications, focusing on probiotics, functional foods, and medical foods [2]. Group 2: Key Product Focus - Human Milk Oligosaccharides (HMOs) - The core technology for Hesheng Biotechnology's HMO products originates from the National Key Basic Research Program (973 Program), with the team first synthesizing HMOs in 2016 and obtaining invention patents for industrial strains [3]. - The company has developed several industrial strain construction technologies for HMOs, including 2'-FL, 3-FL, and others, with a product purity of 98.98%, significantly exceeding domestic and international quality standards [3][4]. Group 3: Research and Application - Hesheng Biotechnology is committed to independent innovation and has initiated research on the functional applications of HMOs, including their role in immune balance and disease intervention [4].

Project Overview - The project is named "Annual Production of 855 Tons of Green Active Raw Materials" and is initiated by Shandong Yunluo Biotechnology Co., Ltd. [2] - The total estimated investment for the project is 100 million yuan, with 7.5% allocated for environmental protection, amounting to 7.5 million yuan [2]. - The construction period is planned for one year, and the project will utilize existing factory buildings while acquiring new production equipment [2]. Production Capacity - Upon reaching full production capacity, the project is expected to produce 1 ton of probiotics, 5 tons of ergothioneine, 126 tons of ectoine, 250 tons of hydroxypropyl tetrahydropyran triol (Bosein), and 473 tons of gluconic acid annually [2][3]. - The products will be sold externally and adhere to the company's quality standards [3]. Company Background - Shandong Yunluo Biotechnology Co., Ltd. is a wholly-owned subsidiary of Shanghai Yunluo Biotechnology Co., Ltd. [3]. - The company focuses on synthetic biology, specializing in enzyme gene mining, directed enzyme modification, cell factory construction, biological fermentation, and enzyme catalysis [3]. Industry Event - The Fourth Synthetic Biology and Green Bio-Manufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang [5]. - The conference will focus on the integration of AI and biological manufacturing, as well as the industrialization progress and opportunities in green chemistry, new materials, future food, and agriculture [5]. - Various stakeholders, including international enterprises, industry experts, and government representatives, will participate to explore trends in biological manufacturing and innovation [5].

Core Insights - The article highlights the upcoming SynBioCon 2025, focusing on advancements in synthetic biology and green manufacturing, scheduled for August 20-22, 2025, in Ningbo, Zhejiang [6][2]. Group 1: Event Overview - SynBioCon 2025 is organized by DT New Materials, with support from various institutions including Peking University Ningbo Institute of Oceanography and Enzyme Bioengineering [6]. - The conference aims to explore the integration of AI in biological manufacturing, advancements in green chemistry, new materials, future food, and agriculture [6]. Group 2: Key Themes and Discussions - The event will cover the "1+3" theme, focusing on AI and biological manufacturing, and will discuss the industrialization progress and opportunities in related fields [6]. - It will feature discussions on the development trends of the biological manufacturing industry during the 14th Five-Year Plan, innovations that sustain the industry, and the transfer of technological achievements [6]. Group 3: Agenda Highlights - The agenda includes a high-level roundtable on biological manufacturing, a youth forum, and several specialized forums on green chemistry, AI in biological manufacturing, and future food and agriculture [7]. - Notable activities include a welcome dinner and a technology achievement exhibition, aimed at fostering collaboration and innovation within the industry [7].

Core Insights - National Investment Group's subsidiary, Guotou Juli, has completed a strategic investment of 450 million RMB in the synthetic biology company Yikolei Biotech, marking another significant investment in the biomanufacturing sector following a previous investment of 300 million RMB in Muen Biotech in 2024 [1][2]. Company Overview - Yikolei Biotech, established in 2015, has developed a comprehensive synthetic biology technology pathway and industrial production capabilities, focusing on enzyme-biosynthesis routes and intelligent cell design [3]. - The company has a diverse product matrix and has become a strategic partner for several industry giants, maintaining a leading position in biomedicine and green agriculture, with recent breakthroughs in the nutrition and health sector [5]. Product Innovations - Yikolei Biotech is the first company in China to receive approval for several functional food ingredients, including HMOs (human milk oligosaccharides), steviol glycosides, and sialic acid [5]. Industry Event - The 2025 Synthetic Biology and Green Biomanufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on AI and biomanufacturing, green chemicals, new materials, future food, and agriculture [7]. - The conference aims to explore the development trends of the biomanufacturing industry during the 14th Five-Year Plan, emphasizing technology transfer, product scaling, and talent acquisition [7].

Core Viewpoint - Zhejiang Kemin Biopharmaceutical Co., Ltd. is advancing its production capabilities by launching a project to produce 1,400 tons of bio-fermentation products annually, focusing on environmentally friendly alternatives to previously planned products [1][2]. Project Overview - Project Name: Annual production of 1,400 tons of bio-fermentation series products and supporting construction project [2] - Project Nature: Technological upgrade [2] - Construction Unit: Zhejiang Kemin Biopharmaceutical Co., Ltd. [2] - Location: Zhejiang Xinchang Economic Development Zone [2] - Scale: The project includes two adjacent closed production lines, one for fermentation processes and another for extraction processes, with advanced equipment to achieve a production capacity of 1,400 tons per year [2]. Product Details - The project will produce various bio-fermentation products, including: - Coenzyme Q10: 1,080 tons/year - Astaxanthin: 100 tons/year - Calcium Pantothenate: 1,090 tons/year - Beta-Carotene: 60 tons/year - Lycopene: 3 tons/year - PQQ: 7 tons/year - Dehydroacetic Acid: 60 tons/year [2]. Financial Performance - Zhejiang Pharmaceutical Co., Ltd. expects a net profit attributable to shareholders of 600 million to 720 million yuan for the first half of 2025, representing a year-on-year increase of 90.28% to 128.33% [2]. - The net profit excluding non-recurring gains and losses is projected to be between 590 million and 708 million yuan, reflecting an increase of 86.27% to 123.53% year-on-year [2]. Market Dynamics - The company is focusing on maintaining safety in production and product quality amidst intense market competition and a complex economic environment [3]. - The demand and sales prices for the company's main products in the life nutrition segment have increased compared to the same period last year, driving revenue growth [3]. Industry Event - The 4th Synthetic Biology and Green Bio-Manufacturing Conference (SynBioCon 2025) will be held from August 20-22, 2025, in Ningbo, Zhejiang, focusing on AI and bio-manufacturing, green chemicals, new materials, future food, and agriculture [4][6].

Core Insights - The Chinese biomanufacturing industry is projected to reach a scale of 1.01 trillion yuan in 2024, with a year-on-year growth of 15.4%. By 2030, the industry is expected to exceed 2.5 trillion yuan, with a compound annual growth rate of 16.8% [1]. Group 1: Industry Overview - The DT New Materials Research Institute has been actively monitoring and supporting the progress and innovation in the synthetic biology sector since the release of the "China Synthetic Biology Industry Map (2023)" which includes over 300 listed companies [1]. - The upcoming "4th Synthetic Biology and Green Biomanufacturing Conference (SynbioCon 2025)" will take place from August 20-22 in Ningbo, Zhejiang, where the "China Synthetic Biology Industry Distribution Map (2025 Edition)" will be announced, featuring over 500 representative biomanufacturing companies and their product information [1][9]. Group 2: Event Details - The conference will focus on five key areas: AI + Biomanufacturing, Green Chemistry and New Materials, Future Food, Future Agriculture, and Beauty Raw Materials, inviting industry leaders, experts, and various stakeholders to explore trends in biomanufacturing development during the 14th Five-Year Plan [9]. - Participants at the conference can receive a free copy of the industry map valued at 499 yuan, and eligible biomanufacturing companies can register to be included in the map [6][10].

Core Insights - The article highlights the rapid development and innovation in China's synthetic biology sector, particularly focusing on Shanghai as a leading hub for synthetic biology initiatives and projects [2][3][4]. Group 1: Industry Development - Shanghai is recognized as the primary force in China's synthetic biology development, with significant milestones such as the establishment of the Chinese Academy of Sciences' synthetic biology laboratory in 2008 [2]. - In 2023, Shanghai released an action plan to accelerate synthetic biology innovation and build a high-end biomanufacturing industry cluster from 2023 to 2025 [2]. - The Shanghai Municipal Science and Technology Commission has initiated key projects in synthetic biology and computational biology to support rapid industry growth [2]. Group 2: Funding and Support - Shanghai has allocated substantial funding for synthetic biology projects, including 42 million yuan for 18 projects and 37 million yuan for 16 projects [3]. - The city has established industrial clusters in areas like Zhangjiang Science City and Lingang New Area, providing comprehensive support from research and development to pilot testing [3]. Group 3: Notable Companies - A total of 66 representative companies from Shanghai have been listed in the "China Biomanufacturing 500+ Representative Enterprises List" based on their team, core products, and competitive potential [4]. - Key companies in the synthetic biology sector include Kasei Biotech, Enkasei Pharmaceutical, and Changjin Biotech, all of which are located in the aforementioned industrial parks [3][4]. Group 4: Upcoming Events - The Fourth Synthetic Biology and Green Biomanufacturing Conference will be held from August 20-22, 2025, in Ningbo, Zhejiang, focusing on AI and biomanufacturing, green chemicals, new materials, future food, and agriculture [19][21]. - The conference aims to gather international enterprises, industry experts, and government representatives to explore trends and innovations in the biomanufacturing sector [19].

Core Viewpoint - Nanjing Membrane Materials is a key player in the development and supply of specialized membrane materials and equipment, focusing on the biomanufacturing industry and participating in the upcoming SynBioCon 2025 conference [1][16]. Group 1: Company Overview - Nanjing Membrane Materials Industry Technology Research Institute is a collaborative innovation entity established with the support of Nanjing University of Technology, focusing on high-performance membrane material research and production, as well as the manufacturing of complete membrane separation equipment [7]. - The company provides integrated technology and equipment for fermentation, enzyme catalysis, separation, and purification processes in bioproducts, with a strong emphasis on engineering applications in the fields of biobased products such as succinic acid, long-chain dicarboxylic acids, and amino acids [7]. Group 2: Product Introduction - High-precision ceramic membranes are designed for the separation and purification of fermentation and enzyme reaction liquids, featuring small and narrowly distributed pore sizes, high flux, and excellent anti-pollution performance [9][10]. - Special nanofiltration membranes are resistant to acids, bases, and solvents, with molecular weight cut-offs of 200, 400, and 600 Da, enabling specific separation needs such as desalting, concentration, and decolorization [11][12]. - The multi-component concentration detection instrument, SENSAP, allows for rapid detection of various substances, including glucose and lactic acid, with a detection time of less than 1 minute and high precision [13][15]. Group 3: Industry Events - The SynBioCon 2025 conference will be held from August 20-22, 2025, in Ningbo, Zhejiang, focusing on AI and biomanufacturing, as well as four key application areas: green chemicals and new materials, future food, future agriculture, and beauty raw materials [16]. - The conference will feature a special session, "Biomanufacturing Youth Forum," aimed at providing insights into scientific issues, solutions, results, scalability, and future directions in the research field [16].

Core Viewpoint - The article emphasizes the significance of biomanufacturing as a key focus for enhancing economic competitiveness in various countries, particularly in China, as part of its manufacturing strength initiatives. The upcoming SynBioCon 2025 conference aims to explore the development trends in biomanufacturing and foster collaboration among industry leaders, experts, and investors [1]. Group 1: Conference Overview - The SynBioCon 2025 will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI and biomanufacturing, along with four application areas: green chemicals and new materials, future food, future agriculture, and beauty ingredients [1]. - The conference will gather international leading companies, industry experts, government representatives, and capital to discuss the trends and innovations in the biomanufacturing sector during the "14th Five-Year Plan" period [1]. Group 2: Organizing Institutions - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and co-organized by institutions such as Peking University Ningbo Institute of Ocean Medicine and Ningbo Enzyme Sai Biological Engineering Co., Ltd. [2]. Group 3: Highlights of the Conference - Key highlights include forums and closed-door discussions on biomanufacturing development trends, sharing of innovative technologies and values, and over 100 financing project roadshows to discover new cooperation opportunities [5]. - The event will feature a high-level closed-door seminar focusing on the development trends and growth points of biomanufacturing, inviting 30 industry leaders and experts for in-depth discussions [9]. Group 4: Agenda and Special Sessions - The first day will include a high-level closed-door seminar and a youth innovation technology forum aimed at discovering potential teams and technologies in biomanufacturing [12]. - The second and third days will feature a macro forum on biomanufacturing, specialized sessions on green chemicals and new materials, AI in biomanufacturing, future food and agriculture, and beauty ingredients [13][15][18]. Group 5: Topics of Discussion - Discussions will cover various topics such as the development of bio-based materials, new carbon source biomanufacturing, and the application of AI in enzyme discovery and industrial fermentation processes [16][17]. - The conference will also explore the biomanufacturing of high-value food ingredients, natural flavors, and the application of biotechnology in cosmetics [20].