Core Insights - The 20th China Dermatology Association (CDA) conference was held in Chongqing, showcasing the advancements in sensitive skin care, with Winona being a prominent participant for the 17th consecutive time [1] - Winona has established itself as a leader in the sensitive skin care market, adhering to the NUTE principle to guide the scientific development of effective skin care products [2][4] Group 1: NUTE Principle and Market Position - The NUTE principle focuses on clinical needs, unique mechanisms, technological empowerment, and credible evidence, addressing the challenges in the rapidly growing effective skin care market [2][4] - Winona has been the top seller in the sensitive skin care market in China for five consecutive years (2020-2024), indicating its strong market presence and authority [6] Group 2: Product Development and Clinical Research - Winona's second-generation special cream targets the core issue of sensitive skin, which is skin barrier damage, utilizing unique active ingredients like Portulaca oleracea extract and Silybum marianum oil [3] - Over the past decade, Winona has conducted more than 56 clinical studies involving 5,590 participants across 61 hospitals, validating the efficacy and safety of its products [3][4] Group 3: PLUS Solutions and Comprehensive Product Matrix - Winona has introduced the sensitive skin PLUS solution, which includes five core products addressing various needs such as repair, post-medical care, sun protection, whitening, and anti-aging [6][7] - The lightening serum has shown significant clinical efficacy in reducing melasma, supported by level I evidence published in the Journal of Cosmetic Dermatology [7] Group 4: Innovations in Treatment for Specific Conditions - Winona has developed the first domestic external antioxidant gel for vitiligo, which combines phototherapy with specific antioxidants to mitigate oxidative damage [8] - The company has been actively involved in establishing clinical guidelines and standards, enhancing the scientific understanding of sensitive skin care within the industry [9] Group 5: Academic Contributions and Industry Standards - Winona's "Red Book 3.0" compiles over 300 authoritative documents, reflecting the evolution of its research system and the growth of the effective skin care academic framework in China [9] - The company continues to push for a scientifically rigorous approach to effective skin care, contributing to the establishment of a comprehensive skin health ecosystem [9]

Core Viewpoint - The article highlights the significance of the NUTE principle in the development of functional skincare products, emphasizing its role in ensuring clinical relevance, unique mechanisms, technological empowerment, and credible evidence in the rapidly growing Chinese functional cosmetics market [12][22][31]. Group 1: Event Overview - The 20th Chinese Medical Association Dermatology Physician Annual Conference (CDA 2025) was held in Chongqing from November 6 to 9, attracting numerous dermatologists and beauty companies, with over 20 participating beauty enterprises [3][4]. - Notable foreign brands such as L'Oréal, Procter & Gamble, and Unilever, along with domestic brands like Betaini and HBN, showcased their products at the event [3][4]. Group 2: Winona's Presentation - Winona made a strong impression at CDA 2025 with 15 academic reports covering hot topics in dermatology, presented by renowned experts [6]. - The exhibition area was themed "Time Research Archive," featuring multiple sections that systematically displayed the brand's research achievements [6][7]. Group 3: NUTE Principle - The NUTE principle consists of four components: Clinical Need, Unique Mechanism, Technology, and Evidence [13][17]. - Winona's development of sensitive skin products is based on clinical needs, identifying key genes like CLDN-5, and utilizing innovative technologies for effective ingredient delivery [17][18]. Group 4: Market Growth and Challenges - The Chinese functional cosmetics market is projected to reach 105.4 billion yuan by 2025, with a compound annual growth rate of 36.03% from 2021 to 2025, significantly outpacing the overall cosmetics market [22]. - However, the market faces challenges with exaggerated claims and varying levels of evidence supporting product efficacy, leading to consumer confusion [25][29]. Group 5: Winona's Achievements - Winona has collaborated with 63 top-tier hospitals for clinical observations, covering over 19,000 individuals, and has published 493 papers in SCI and core journals [9]. - The brand has maintained its position as the top seller in the sensitive skin care market in China for five consecutive years from 2020 to 2024 [9].

Core Insights - The core viewpoint of the articles highlights the rapid growth of the Chinese dermatological skincare market, with Winona emerging as a leading brand due to its focus on efficacy and safety in sensitive skin care products [1][3][12]. Market Overview - In 2024, the Chinese dermatological skincare market is projected to reach 33.96 billion yuan, showcasing significant expansion over the past fifteen years [1]. - Winona has established itself as the market leader in this segment, emphasizing its unique approach to product development and clinical validation [1][3]. Brand Development - Winona entered the market in 2010 with a focus on sensitive skin, leveraging its background in the OTC industry to develop effective skincare products based on pharmaceutical standards [3][4]. - The brand has maintained a strong commitment to research and development, with a reported investment of 337 million yuan in 2024, consistently achieving over 5% annual R&D investment [7]. Product Innovation - Winona's product development is guided by the NUTE principle, which stands for Need, Unique, Technology, and Evidence, ensuring that products address clinical needs and are backed by scientific validation [4][5]. - The brand has successfully launched new products targeting advanced needs such as anti-aging for sensitive skin, expanding its product line beyond basic care [8]. Strategic Positioning - Winona aims to become the world's leading efficacy skincare brand, integrating international research resources and establishing laboratories in France and Japan, with plans for a research center in Israel [8][9]. - The company is focused on transforming Yunnan's unique plant resources into competitive advantages, enhancing its value chain from low-end to high-end [8][9]. Consumer Engagement - Winona has developed a robust membership program with approximately 40 million members, emphasizing value-added services and solutions for sensitive skin issues [11]. - The brand's marketing strategy centers on embedding the message "for sensitive skin, use Winona" into consumer consciousness [11]. Industry Contribution - Winona is committed to promoting high-quality development standards in the skincare industry, addressing challenges such as product homogeneity and safety concerns [12]. - The brand has published significant research contributions, including a comprehensive guide on efficacy skincare, which consolidates expert guidelines and clinical studies [12].

张爱玲曾说：" 人生有三恨：一恨海棠无香，二恨鲥鱼多刺，三恨红楼梦未完。 "事实上"鱼 与熊掌不可兼得"的遗憾在化妆品行业也一直存在，尤其是围绕敏感肌的抗老需求。 一方面，随着环境压力与生活方式的改变，全球女性敏感肌人群在持续扩大。 据复旦大学附属华山医院、中国非公立医疗机构协会皮肤专业委员会终身名誉主委郑志忠教授 介绍： 中国女性敏感性皮肤的占比逐渐走高，在部分区域性的流调中，敏感肌的发生率甚至 达5 0%以上 。 而2 0 1 7年发表的《中国敏感性皮肤诊疗专家共识》显示，敏感性皮肤在世界各国均有较高的 发 生 率 ， 欧 洲 为 2 5 . 4% ～ 8 9 . 9% ， 澳 洲 约 为 5 0% ， 美 洲 女 性 为 2 2 . 3% ～ 5 0 . 9% ， 亚 洲 女 性 为 4 0%～5 5 . 9 8%。 而由专业皮肤科医生在2 0 2 4年" 5 2 5全国护肤日"期间进行的一项调查更是显示：7 2 . 1%的受调 查对象皮肤处于亚健康或者病态状态。 与此同时，敏感性皮肤人群对功效护肤，尤其是对抗老需求却在直线上升。 这背后源于一个扎心的事实。四川大学华西医院、中国抗衰老促进会皮肤慢病管理 ...