Summary of Conference Call Records Industry Overview - The pharmaceutical industry is projected to see a revenue decline of 0.46% in 2024, with net profit attributable to shareholders decreasing by 6.7% and non-recurring net profit declining by approximately 11% [1][4] - In Q1 2025, the fastest-growing sectors include medical services, CXO, and raw materials, while community pharmacies and research services lead in revenue growth [1][4] Key Insights on Specific Sectors Innovative Drug Sector - 23 innovative companies reported a total revenue of 62.8 billion yuan in 2024, reflecting a year-on-year growth of 23.8%, with net profit attributable to shareholders reaching 3.7 billion yuan, significantly outpacing the industry average [1][5] - In Q1 2025, these companies achieved a total revenue of 16.3 billion yuan, marking an 18.7% year-on-year increase, indicating a trend towards profitability [5] Research Services Industry - The research services sector saw a total revenue growth of 6.5% in 2024, although profits declined by 20%-16% [6] - In Q1 2025, total revenue grew by 4.7%, with scale profit increasing by 9% and non-recurring profit rising by 13%, indicating a recovery phase compared to the overall industry decline of 5% [6][7] CXO Industry - The CXO sector experienced a revenue decline in 2024 but rebounded in Q1 2025 with a 13% year-on-year revenue growth and a 23% increase in non-recurring net profit, showcasing strong development potential [8] Chemical Preparations Sector - The chemical preparations industry reported stable revenue in 2024, with a slight increase of 1.2%, and a minimal growth of 0.3% in Q1 2025, indicating a phase of stability [9][10] Raw Materials Sector - The raw materials sector faced a revenue decline of 3.8% in Q1 2025, following a 3.9% decrease in 2024, but non-recurring profit grew by 5%, suggesting that the most challenging phase post-pandemic has passed [10] Medical Devices and Traditional Chinese Medicine - The medical devices industry is projected to grow by 1% in 2024 and 0.3% in Q1 2025, with noticeable profit declines potentially linked to centralized procurement policies [11] - The traditional Chinese medicine sector experienced a 6% revenue decline in Q1 2025 due to high base effects, following a 3.9% decrease in 2024 [11] GLP-1 Receptor Agonists Developments - The development of GLP-1 receptor agonists is trending towards oral formulations and extended half-lives, with multi-target drugs becoming a research focus [3][14] - Notably, the revenue for semaglutide surpassed that of pembrolizumab, indicating strong consumer demand [13] - Companies such as Innovent Biologics, Federated Pharmaceuticals, and Boryung Pharmaceutical are making significant strides in the GLP-1 space [16] Market Performance - The overall pharmaceutical sector saw a 1% increase this week, with a year-to-date rise of 1.2%, slightly underperforming compared to the CSI 300 index, which fell by 1% [2] - Notable individual stock performances included Changshan Pharmaceutical (up 23%), Haichuang Pharmaceutical (up 22%), and Jinkai Biotechnology (up 19%) [2] Conclusion - The pharmaceutical industry is navigating a challenging landscape with mixed performance across sectors, but innovative drugs and specific niches like GLP-1 receptor agonists show promising growth potential. The recovery signs in research services and CXO sectors are noteworthy, indicating potential investment opportunities.

Summary of the Conference Call Records Industry Overview: Pharmaceutical Sector Key Points on Industry Performance - In 2024, the biopharmaceutical sector is expected to stabilize in revenue, but profits are under pressure; the chemical preparation sector shows significant cost reduction and efficiency improvement, with A-share revenue growing by 5% year-on-year and non-recurring net profit increasing by 24%, mainly due to the release of innovative products and milestone revenue from business development [1][2][3] - The innovative drug companies are entering a high-speed development phase, with sample hospital data indicating a revenue growth rate of 60% year-on-year; the number of drug registration certificates has significantly increased from 2019 to 2024, and leading companies are improving operational efficiency, resulting in enhanced profitability [1][6] - In Q1 2025, there was a significant increase in holdings of chemical preparations and other biopharmaceuticals by both pharmaceutical and non-pharmaceutical funds, indicating a rising interest in innovative drug companies; despite some recovery in overall valuation, the pharmaceutical sector remains at a historical low, presenting investment opportunities [1][8] Financial Performance Insights - The overall profitability of the pharmaceutical sector has improved, with the chemical preparation sector showing a notable optimization in sales expense ratio, which decreased by 2.4 percentage points year-on-year in 2024; however, the biopharmaceutical sector's revenue growth rate declined by 1 percentage point in 2024, with an 8% year-on-year increase in Q1 2025 [2][3] - In Q1 2025, Ganli Pharmaceutical's insulin product price increase led to a 100% year-on-year net profit growth, while Tonghua Dongbao's profit fell by 49%, primarily due to the impact of a new round of insulin centralized procurement [1][10] Company-Specific Developments - In Q1 2025, companies like Rongchang Bio and Junshi are narrowing their losses, with core products accelerating profitability; a positive development trend is expected over the next three years [1][11] - The chemical preparation sector's revenue growth for large pharmaceutical companies remained stable, while smaller companies faced short-term profit pressures; high-barrier and innovative transformation companies performed well [3][12] Investment Recommendations - Recommended companies in the Pharma sector include Heng Rui, Han Sen Pharmaceutical, China Biologics, and others; in the Biotech sector, companies like BeiGene, Innovent Biologics, and others are highlighted for their strong competitive positions and promising core products [1][9] Market Trends and Valuation - The pharmaceutical sector's overall valuation is at a historical low, with significant recovery signs since 2025; the biopharmaceutical and chemical preparation sectors are particularly noted for their growth potential [1][22] - The active public funds' holdings in the pharmaceutical sector increased to 10% in Q1 2025, reflecting a growing interest in the sector, especially in innovative drugs [16][17] Additional Insights - The performance of the insulin sub-sector in Q1 2025 showed a stark contrast between Ganli Pharmaceutical and Tonghua Dongbao, driven by pricing strategies influenced by centralized procurement [10] - The focus of funds on different sub-sectors indicates a shift, with significant increases in holdings in chemical preparations and biopharmaceuticals, while medical devices and consumables are also gaining attention from non-pharmaceutical funds [18][20]

Group 1 - Dashi Intelligent signed a smart hospital project contract worth 58.12 million yuan with the First Affiliated Hospital of Bengbu Medical College and Bengbu Urban Construction Investment Development Co., Ltd. [1] - The project aims to create a comprehensive tumor specialty hospital integrating medical care, research, teaching, preventive health care, and rehabilitation, which is expected to positively impact the company's future performance [1] Group 2 - Huahong Company reported a net profit of 22.76 million yuan for Q1 2025, a year-on-year decrease of 89.73%, despite a revenue increase of 18.66% to 3.913 billion yuan [2] - The company specializes in the development and application of embedded/non-volatile memory, power devices, and other semiconductor technologies [2] Group 3 - Jindi Group announced a signed area of 214,000 square meters in April, a year-on-year decrease of 55.14%, with a signed amount of 2.78 billion yuan, down 55.45% [3] - The company focuses on real estate development and sales, commercial real estate, and property management [3] Group 4 - Jinlong Automobile reported a bus production of 4,361 units in April, a year-on-year decrease of 5.79%, with sales of 3,611 units, down 3.91% [4][5] - The company is engaged in the production and sales of bus products [5] Group 5 - Sanyou Medical established a joint venture with CGBio Co., Ltd. with a registered capital of 60 million yuan, focusing on innovative cell biological materials and regenerative medicine [6][7] - The company specializes in the research, production, and sales of orthopedic implant consumables [7] Group 6 - Jinzhi Technology won a bid for projects related to the State Grid with a total amount of 90.73 million yuan, accounting for 5.12% of the company's projected revenue for 2024 [9][10] - The company focuses on smart energy and smart city businesses [10] Group 7 - Pinggao Electric won multiple procurement projects from the State Grid, totaling approximately 1.751 billion yuan, which is 14.12% of the company's projected revenue for 2024 [10] - The company specializes in high-voltage switchgear and power engineering contracting [10] Group 8 - Luantang Pharmaceutical received approval for the raw material drug Celecoxib, which is a selective COX-2 inhibitor with fewer gastrointestinal side effects compared to traditional NSAIDs [11][12] - The company is involved in the research, production, and sales of pharmaceutical products [12] Group 9 - Dongjie Intelligent obtained seven patent certificates related to AGV and conveyor system technologies [13][14] - The company specializes in the research, design, manufacturing, installation, and debugging of intelligent logistics systems [14] Group 10 - XJH Holdings received a government subsidy of 8.69 million yuan, which accounts for 38.67% of the company's projected net profit for 2024 [15][16] - The company focuses on the recycling and dismantling of waste electrical products [16] Group 11 - Huaihua Pharmaceutical's subsidiary received approval for the clinical trial of HZ-J001 ointment for treating non-segmental vitiligo [17][19] - The company is engaged in the research, production, and sales of pharmaceutical products [19] Group 12 - ST Aonong reported a pig sales volume of 132,800 heads in April, a year-on-year decrease of 14.42%, while the stock of pigs increased by 15.06% [22][23] - The company is involved in feed, pig farming, food, and trade [23] Group 13 - Beibu Gulf Port reported a cargo throughput of 31.75 million tons in April, a year-on-year increase of 20.32% [24][25] - The company specializes in port loading, storage, and related services [25] Group 14 - Dongfang Iron Tower won a bid for State Grid projects totaling approximately 100 million yuan, which is 2.39% of the company's projected revenue for 2024 [26] - The company focuses on steel structures and related businesses [26] Group 15 - Huanxu Electronics reported a consolidated revenue of 4.641 billion yuan in April, a year-on-year increase of 0.72% [27] - The company provides design, manufacturing, and related services for brand customers [27] Group 16 - Jincheng Co. announced that part of its bank accounts has been frozen, involving approximately 32.97 million yuan due to contract disputes [28][29] - The company specializes in high-end intelligent equipment for photovoltaic and smart port sectors [29] Group 17 - NAIKE Equipment announced the departure of core technical personnel Wang Xiangguo [30][31] - The company focuses on semiconductor packaging equipment and related products [31] Group 18 - Jiaojian Co. won a construction project in Hefei with a bid amount of approximately 704 million yuan, covering residential buildings and related infrastructure [32][33] - The company specializes in infrastructure construction and related services [33] Group 19 - Hongyuan Green Energy plans to transfer a 27.07% stake in Inner Mongolia Xinyuan Silicon Material Technology Co., Ltd. for 1.245 billion yuan [34][35] - The company focuses on the research, production, and sales of aviation electromechanical products [35] Group 20 - Poly Development reported a signed amount of 24.622 billion yuan in April, a year-on-year decrease of 25.44% [46][48] - The company specializes in real estate development and sales [48]

医药生物行业 超配（维持） Q1 板块业绩承压，关注细分景气方向 医药生物行业 2024 年及 2025 年一季度业绩综述 投资要点： 本报告的风险等级为中高风险。 本报告的信息均来自已公开信息，关于信息的准确性与完整性，建议投资者谨慎判断，据此入市，风险自担。 请务必阅读末页声明。请务必阅读末页声明。 分析师：谢雄雄 SAC 执业证书编号： S0340523110002 电话：0769-22110925 邮箱： 分析师：魏红梅 SAC 执业证书编号： S0340513040002 电话：0769-22119462 邮箱：whm2@dgzq.com.cn 医药生物（申万）指数走势 资料来源：东莞证券研究所，Wind 相关报告 证 券 研 究 报 告 业 绩 综 述 行 业 研 究 2025 年 5 月 8 日 xiexiongxiong@dgzq.com.cn ◼ 2024年行业整体营收和归母净利润同比有所下滑。2024年，SW（2021）医 药生物行业实现营业总收入2.46万亿元，同比下滑1.0%，增速同比下滑1.8 个百分点；实现归属于母公司股东的净利润1,402.6亿元，同比下降13.1%， 增速同比上 ...

Investment Rating - The industry investment rating is "stronger than the market" indicating an expected performance that exceeds the market by more than 5% over the next six months [49]. Core Views - The chemical agents and blood products sectors are expected to perform outstandingly in 2024, with positive revenue and profit growth reported in the CXO and medical services (hospitals) sectors for Q1 2025 [4][5]. - The biopharmaceutical industry is anticipated to outperform the market overall [4]. Summary by Sections Industry Performance - As of April 30, 2025, 467 A-share biopharmaceutical companies reported their 2024 annual and Q1 2025 results. In 2024, 28 companies had revenue growth exceeding 30%, while 50 companies exceeded 20%, and 113 companies exceeded 10%. Approximately 220 companies reported positive revenue growth, while 246 experienced negative growth. On the profit side, 102 companies had profit growth over 30%, 132 over 20%, and 172 over 10%, with 218 maintaining positive profit growth and 249 facing negative growth [4]. - In Q1 2025, 24 companies reported revenue growth over 30%, 52 over 20%, and 109 over 10%, with 214 maintaining positive revenue growth and 251 reporting negative growth. For profits, 100 companies had growth over 30%, 120 over 20%, and 159 over 10%, with 220 maintaining positive profit growth and 240 facing negative growth [4]. Investment Strategies - Focus on "innovation," "going global," "equipment upgrades," and "consumption recovery." - **Innovation**: Invest in globally competitive innovative drugs and categories with significant market potential. Recommended companies include BeiGene, Dongcheng Pharmaceutical, and others [7]. - **Going Global**: Explore overseas markets for long-term opportunities, with companies like Mindray Medical and others highlighted [7]. - **Equipment Upgrades**: Expect support for medical equipment updates from central and local government financing, with companies like Mindray Medical and others recommended [7]. - **Consumption Recovery**: Anticipate recovery in quality sectors like ophthalmology and medical aesthetics, with companies such as Puri Eye Hospital and others suggested [7]. Key Companies to Watch - **Nocare Biopharma**: Expected to achieve over 1 billion yuan in revenue from its core product, with a 49% year-on-year sales increase. The company reported a gross margin of 86.3% and a significant reduction in losses [8]. - **Sihuan Pharmaceutical**: Strong fundamentals with core products maintaining growth, and a robust pipeline expected to yield multiple approvals from 2025 to 2027 [11]. - **China Biopharmaceutical**: Rapid revenue growth with an increasing share of innovative products, and a strong pipeline in oncology [13]. - **Aibo Medical**: Anticipated growth in high-end artificial lenses and recovery in consumption due to aging trends [23]. Industry News Highlights - BeiGene's Sonrotoclax NDA application has been accepted for review, indicating potential market entry for a new treatment for CLL/SLL [30]. - Novartis' Pluvicto has received acceptance for a new indication in China, expanding its market potential [31]. - The partnership between Fuhong Hanlin and Sandoz for HLX13 indicates a significant milestone in the commercialization of biosimilars [33].

Investment Rating - The industry investment rating is "stronger than the market" indicating an expected performance that exceeds the market by more than 5% over the next six months [50]. Core Insights - The chemical agents and blood products sectors showed outstanding performance in 2024, while the CXO and medical services (hospitals) sectors reported positive growth in both revenue and profit for Q1 2025 [4][5]. - As of April 30, 2025, among 467 selected A-share biopharmaceutical companies, 28 companies reported revenue growth exceeding 30% for 2024, while 50 companies had growth over 20% [4]. - In Q1 2025, 24 companies achieved revenue growth greater than 30%, and 100 companies reported profit growth exceeding 30% [4]. Summary by Sections Industry Performance - In 2024, the chemical agents and blood products sectors maintained positive growth in both revenue and profit [5]. - For Q1 2025, the CXO and medical services sectors also reported positive growth in revenue and profit [5]. Investment Strategy - Focus on "innovation," "going global," "equipment upgrades," and "consumption recovery" as key investment themes [7]. - Recommended companies for "innovation" include BeiGene, Dongcheng Pharmaceutical, and others [7]. - For "going global," companies like Mindray Medical and Sinopharm are highlighted [7]. - In "equipment upgrades," companies such as Mindray Medical and Aohua Medical are suggested [7]. - Under "consumption recovery," companies like Puri Eye Hospital and Tongce Medical are noted [7]. Key Companies to Watch - **Nocera Health**: Achieved revenue of 1.009 billion yuan in 2024, with a 49% year-on-year increase in sales of its core product, Obinutuzumab [8]. - **Sihuan Pharmaceutical**: Maintained a stable performance with core products continuing to grow [11]. - **China Biopharmaceutical**: Rapid revenue growth with an increasing proportion of innovative products expected to accelerate profit growth [13]. - **Aibao Medical**: The launch of its self-developed ICL lens is expected to drive significant revenue growth [23]. Industry News Highlights - BeiGene's Sonrotoclax new drug application has been accepted for review [30]. - Novartis' Lutetium-177 injection has been accepted for a new indication in China [31]. - Fuhong Hanlin signed a licensing agreement with Sandoz for HLX13 [33]. - BeiGene won a patent dispute, strengthening its market position for its BTK inhibitor [34].

Investment Rating - The report maintains a "Buy" rating for the company, indicating an expected relative price increase of over 20% compared to the market benchmark within the next six months [17]. Core Views - The company reported a revenue of 1.51 billion yuan for Q1 2025, reflecting a year-on-year growth of 11.3%, and a net profit of 300 million yuan, which is a 13.4% increase year-on-year [2]. - The increase in various expense ratios in Q1 2025, including sales expense ratio at 33.6% (up 1.5 percentage points), management expense ratio at 4.9% (up 1.4 percentage points), and R&D expense ratio at 12.7% (up 2.2 percentage points), is attributed to stock incentive costs and increased R&D investments [3]. - The company continues to increase its R&D investment, with a total of 721 million yuan in 2024, a 17.48% increase year-on-year, and a workforce of 911 R&D personnel, up 6.7% year-on-year. The company has 14 innovative drug projects in progress, with significant advancements expected in 2024 [4]. Financial Forecast and Investment Recommendations - The company is projected to achieve revenues of 6.59 billion yuan, 7.69 billion yuan, and 8.93 billion yuan for 2025, 2026, and 2027 respectively, with growth rates of 16%, 17%, and 16% [5]. - The net profit forecast for the same years is 1.31 billion yuan, 1.52 billion yuan, and 1.78 billion yuan, with growth rates of 15%, 16%, and 17% [5]. - The earnings per share (EPS) are expected to be 1.29 yuan, 1.50 yuan, and 1.75 yuan for 2025, 2026, and 2027 respectively [5]. - The company is considered to be relatively undervalued, and the report maintains a "Buy" rating based on its growth potential and diverse product pipeline [5].

Investment Rating - The report indicates a cautious outlook for the pharmaceutical industry, with a focus on recovery in 2024 after a challenging 2023 due to anti-corruption measures [6][19]. Core Insights - The pharmaceutical industry is projected to see a decline in sales revenue and net profit for 2024 compared to 2023, with total sales revenue growth at -0.46%, net profit at -6.73%, and non-recurring net profit at -11.97% [2][13]. - The fastest-growing segments in Q4 2024 are expected to be CXO, medical devices, and pharmaceutical distribution, while in Q1 2025, the growth leaders will shift to CXO, pharmacies, and pharmaceutical distribution [22]. - The report highlights a significant slowdown in growth for traditional Chinese medicine and a mixed performance across various sectors, with some showing resilience and others facing challenges [5][24]. Summary by Sector Pharmaceutical Industry - In 2024, the total revenue growth for 405 pharmaceutical companies is projected at -0.46%, with net profit declining by 6.73% [2][13]. - Q1 2025 shows a continued decline in revenue and net profit, indicating ongoing challenges [13]. Traditional Chinese Medicine - For 62 listed companies in traditional Chinese medicine, revenue and net profit are expected to decline by -3.9% and -14.6% respectively in 2024, with further declines in Q1 2025 [24][32]. Chemical Preparations - The 96 chemical preparation companies are expected to see revenue growth of 1.2% and net profit growth of 15.7% in 2024, with a slight slowdown in Q1 2025 [2][5]. Research Services - The 16 research service companies are projected to experience a revenue increase of 6.56% in 2024, despite a significant drop in net profit [2][5]. Medical Services - The 11 medical service companies are expected to face revenue growth of 1.4% in 2024, with a notable recovery in Q1 2025 [2][5]. Medical Devices - The 97 medical device companies are projected to see a slight revenue increase of 1.16% in 2024, with a decline in net profit [2][5]. Biopharmaceuticals - The 54 biopharmaceutical companies are expected to see a revenue decline of -6.9% in 2024, with a significant drop in Q1 2025 [3][5]. CXO - The 22 CXO companies are projected to experience a revenue decline of -4.14% in 2024, but a recovery is anticipated in Q1 2025 with a revenue increase of 13.1% [3][5]. Raw Materials - The 50 raw material companies are expected to see a slight revenue increase of 2.48% in 2024, with a recovery trend starting in Q1 2025 [3][5]. Pharmacies - The 7 pharmacy companies are projected to see revenue growth of 4.9% in 2024, but face challenges in Q1 2025 [2][5]. Pharmaceutical Distribution - The 22 pharmaceutical distribution companies are expected to see a slight revenue increase of 0.27% in 2024, with ongoing challenges in Q1 2025 [2][5].

上天天基金APP搜索【777】领 98 元券包 ，优选基金10元起投！限量发放！先到先得！ 作为资本市场的重要"稳定器"和"压舱石"，社保基金凭借审慎稳健的投资运营管理，已经成为A股市场 长期投资、理性投资的典范。 根据A股上市公司2025年一季报披露，截至4月28日记者发稿，一季度末已有324家公司前十大流通股股 东名单中出现社保基金的身影，社保基金最新投资路线图逐次揭晓。东方财富Choice数据显示，上述 324家公司累计获社保基金重仓持股54.97亿股，对应持股市值为853.85亿元。 社保基金新进持有100家上市公司 今年一季度，社保基金对云铝股份、华鲁恒升、常熟银行、万华化学、赤峰黄金、广汇能源、西部超 导、新奥股份、宇通客车、宝钢股份、长城汽车等15家公司的重仓持股市值超过10亿元。其中，社保基 金持有云铝股份1.45亿股，对应持仓市值为25.13亿元；持有华鲁恒升1.06亿股，对应持仓市值23.42亿 元；持有常熟银行2.54亿股，对应持仓市值为17.7亿元；持有万华化学2121万股，对应持仓市值为14.26 亿元；持有赤峰黄金6145.75万股，对应持仓市值为14.07亿元；持有广汇能源2.1 ...

Investment Rating - The report rates the pharmaceutical industry as "Overweight" [1] Core Insights - The total market capitalization of pharmaceutical stocks in public offering funds increased from RMB 233.40 billion to RMB 238.30 billion, reflecting a growth of 2% [30][31] - The proportion of pharmaceutical stocks in all fund holdings slightly increased to 7.87%, up by 0.36 percentage points from the previous quarter [31] - The report expresses optimism about the growth potential of the pharmaceutical industry, driven by continuous technological innovation and demand [30] Summary by Sections 1. Fund Holdings Ratio - The proportion of pharmaceutical stocks in public funds saw a slight recovery, with a total market cap increase from RMB 233.40 billion to RMB 238.30 billion [6][30] - As of Q1 2025, pharmaceutical stocks accounted for 7.87% of all public offering fund long positions, an increase of 0.36 percentage points from Q4 2024 [31] 2. Sector Analysis - The leading sectors in public fund holdings of pharmaceutical stocks in Q1 2025 were: 1) Chemical preparations: RMB 85.20 billion, 36% 2) Medical devices: RMB 44.70 billion, 19% 3) Medical R&D outsourcing: RMB 44.50 billion, 19% [32][10] 3. Top Holdings - The top five public offering fund long positions by market capitalization in Q1 2025 were: 1) Jiangsu Heng Rui Medicine: RMB 32.30 billion 2) WuXi AppTec: RMB 27.60 billion 3) Mindray Medical: RMB 25.60 billion 4) United Imaging: RMB 9.80 billion 5) BeiGene: RMB 9.00 billion [33][20] - The top five growth in public offering fund long positions by market capitalization were: 1) WuXi AppTec: +RMB 6.20 billion 2) BeiGene: +RMB 4.40 billion 3) Sichuan Kelun Pharmaceutical: +RMB 2.60 billion 4) Jiangsu Heng Rui Medicine: +RMB 2.40 billion 5) Pharmaron: +RMB 0.90 billion [25][33]