2025年7月11日至13日，全球医美界瞩目的国际医学（000516）美容抗衰老大会（IMCAS）于上海成功 举办。作为医美领域最具影响力的国际学术盛会，本届大会汇聚了近200位全球顶尖专家及数千名行业 精英，围绕整形外科、注射美容等前沿议题展开深入交流与探讨。英卡思大会始终致力于搭建全球医美 专业人士的学术桥梁，通过汇集国际前沿科研成果与创新理念，推动跨地域、跨学科的深度协作，持续 突破现有治疗技术的边界，为求美者带来更安全、更精准的医疗美容解决方案。 图1：2025·国际医学美容抗衰老大会（IMCAS）现场 7月13日，在注射并发症专场，薛志强博士发表了题为《胶原刺激剂引发结节肉芽肿的等离子射频消融 治疗》的学术演讲。这也是他本次大会针对馒化修复的第二场深度报告。薛志强博士在演讲中指出，随 着医美行业的快速发展，注射美容并发症的发生率正逐年上升，其中以玻尿酸、胶原刺激剂等注射物残 留所导致的团块和结节问题尤为常见。他强调，此类修复的关键在于精准定位与针对性处理，盲目操作 不仅难以解决问题，还可能进一步加重组织损伤。 针对胶原刺激剂（再生材料）引发的结节或肉芽肿，俊泰医疗薛志强博士提出了分级治疗策略："我们 ...

Core Insights - The medical beauty materials market is entering a competitive phase in 2025, with significant approvals for new materials such as agarose and hydroxyapatite, indicating a growing diversity of products [1][10] - The approval of various injection fillers, including recombinant collagen and animal-derived collagen, highlights the rapid development and commercialization of medical beauty materials [1][4] - Investment in medical beauty materials companies has surged, with 12 companies securing funding in the first five months of 2025, reflecting strong interest from investors [4][5] Regulatory Approvals - Hydroxyapatite received two approvals in 2025, with the first compliant product for medical beauty injections approved in February [10] - Agarose also saw its first approval in January 2025, marking a significant milestone for this material in the domestic market [10] - Over 110 products for medical beauty injections have been approved in China, primarily classified as Class III medical devices [2][4] Market Dynamics - The competition for the first regulatory approval (Class III certificate) is intense, as it provides a significant market advantage [10][12] - Companies are increasingly focusing on developing new materials and applications, with many aiming to secure the first approval in various new material categories [11][12] - The market is characterized by a mix of established companies and startups, all vying for a share of the growing medical beauty sector [15][16] Investment Trends - Notable investments in medical beauty materials companies include significant funding rounds for firms like 聚源生物 and 未名拾光, indicating robust investor confidence [5][6] - The trend of startups receiving funding is expected to continue, as the demand for innovative medical beauty solutions grows [4][5] Product Development - Companies are exploring the combination of different materials to enhance product competitiveness, with a focus on safety and efficacy [14][15] - New materials such as PDRN, silk protein, and chitosan are being investigated for their applications in medical beauty and functional skincare [16][17] - The development of multi-indication products is becoming a strategic focus, with companies aiming to address various aesthetic needs [13][15] Future Outlook - The medical beauty market is anticipated to expand, driven by the introduction of new materials and innovative applications [16][17] - The interplay between medical beauty and skincare sectors is expected to create a positive feedback loop, enhancing market growth [16][17] - Ultimately, the success of new materials will depend on their clinical validation and real-world application, as safety and effectiveness remain paramount [16][17]

Core Insights - The skincare market for international brands like Estée Lauder and L'Oréal is facing challenges, prompting a shift towards the medical aesthetics sector [1][4] - Estée Lauder has partnered with Jiahui Medical to establish a clinical research center focused on post-surgical skincare solutions [1][5] - The beauty industry is witnessing a trend towards "medical beauty," with brands integrating effective skincare products with medical aesthetics [4][6] Group 1: Company Strategies - Estée Lauder's brands, including La Mer and Clinique, are launching medical device products aimed at post-surgical recovery, indicating a strategic pivot towards medical aesthetics [1][5] - L'Oréal has been proactive in the medical aesthetics space, introducing products like the "Platinum Research" collagen injection and investing in high-end medical chains [6][7] - Amorepacific has also entered the market with its high-end brand "AP," focusing on post-surgical skincare products priced between 2000-3000 RMB [5][6] Group 2: Market Dynamics - The high-end skincare market is experiencing a significant decline, with Estée Lauder reporting an 8% drop in skincare sales in Q3 2024 and a further 12% in Q4 2024, leading to a total revenue loss of $300 million [4] - Competitors like Beiersdorf are also struggling, with its luxury brand La Prairie seeing a 15% sales decline in 2023 and a 6% drop in 2024 [4] - The domestic medical aesthetics market is becoming increasingly competitive, with companies like Aimeike facing growth slowdowns despite a 5.45% revenue increase in 2024 [9][10] Group 3: Future Outlook - Aimeike's acquisition of an 85% stake in Korean company REGEN for approximately 1.4 billion RMB highlights the need for companies to strengthen their technological capabilities in the face of rising competition [11] - The competition between international beauty brands and domestic medical aesthetics firms is intensifying, focusing on brand strength and clinical validation versus technological barriers and channel control [11]

Core Insights - The domestic market is on the verge of launching its first PDRN product, with Jiangsu Wuzhong completing clinical trials and planning to submit for market approval in the second half of the year [1][2][3] - PDRN, known as "salmon needle" in the aesthetic medicine market, has gained significant attention due to its ability to stimulate collagen and elastin production, making it valuable for skin repair and anti-aging [3][5] - The global PDRN market is projected to grow fivefold in the next five years, reaching $285 million by 2029, with China expected to have the highest growth rate at a compound annual growth rate (CAGR) of 49.02% from 2023 to 2029 [9][10] Industry Dynamics - Over 20 domestic companies are currently involved in the PDRN sector, including major players like Huaxi Biology and Jiangsu Wuzhong, indicating a competitive landscape [3][5] - The initial applications of PDRN were in wound healing and tissue regeneration, but its efficacy in anti-aging has led to a shift towards aesthetic applications [5][6] - The entry of domestic companies into the PDRN market has been accelerated by significant investments and acquisitions, highlighting the commercial potential of PDRN products [6][19] Market Competition - The current market is dominated by imported PDRN products, primarily from South Korea, which poses a challenge for domestic brands to establish themselves [10][12] - The success of Korean brands in China has been attributed to tailored product offerings and effective marketing strategies, including partnerships with beauty institutions [15][19] - Domestic PDRN products have the opportunity to capture market share by focusing on compliance and quality, as existing products lack regulatory approval [18][19] Future Outlook - The first approved PDRN product is expected to create a significant market opportunity, potentially becoming a blockbuster in the aesthetic medicine sector [18][19] - The competition among aesthetic products, including PDRN, PLLA, and PCL-based injections, will intensify as companies innovate and seek to differentiate their offerings [21][23] - The strategic focus on product compliance, market education, and efficient distribution will be crucial for domestic companies to succeed in the evolving landscape of aesthetic medicine [19][23]