Core Insights - The medical beauty materials market is entering a competitive phase in 2025, with significant approvals for new materials such as agarose and hydroxyapatite, indicating a growing diversity of products [1][10] - The approval of various injection fillers, including recombinant collagen and animal-derived collagen, highlights the rapid development and commercialization of medical beauty materials [1][4] - Investment in medical beauty materials companies has surged, with 12 companies securing funding in the first five months of 2025, reflecting strong interest from investors [4][5] Regulatory Approvals - Hydroxyapatite received two approvals in 2025, with the first compliant product for medical beauty injections approved in February [10] - Agarose also saw its first approval in January 2025, marking a significant milestone for this material in the domestic market [10] - Over 110 products for medical beauty injections have been approved in China, primarily classified as Class III medical devices [2][4] Market Dynamics - The competition for the first regulatory approval (Class III certificate) is intense, as it provides a significant market advantage [10][12] - Companies are increasingly focusing on developing new materials and applications, with many aiming to secure the first approval in various new material categories [11][12] - The market is characterized by a mix of established companies and startups, all vying for a share of the growing medical beauty sector [15][16] Investment Trends - Notable investments in medical beauty materials companies include significant funding rounds for firms like 聚源生物 and 未名拾光, indicating robust investor confidence [5][6] - The trend of startups receiving funding is expected to continue, as the demand for innovative medical beauty solutions grows [4][5] Product Development - Companies are exploring the combination of different materials to enhance product competitiveness, with a focus on safety and efficacy [14][15] - New materials such as PDRN, silk protein, and chitosan are being investigated for their applications in medical beauty and functional skincare [16][17] - The development of multi-indication products is becoming a strategic focus, with companies aiming to address various aesthetic needs [13][15] Future Outlook - The medical beauty market is anticipated to expand, driven by the introduction of new materials and innovative applications [16][17] - The interplay between medical beauty and skincare sectors is expected to create a positive feedback loop, enhancing market growth [16][17] - Ultimately, the success of new materials will depend on their clinical validation and real-world application, as safety and effectiveness remain paramount [16][17]

国内首款"三文鱼针"即将问世，又一大单品已到爆发前夜？ 文 | 动脉网 再生领域风水轮流转，这次终于轮到了PDRN。 先是在今年1月，瑞吉明生物宣布已成功研制出全球首款人工合成PDRN原料，并中试成功。2个月后，也就是近日，江 苏吴中也传来好消息，旗下注射用透明质酸钠-多聚脱氧核糖核苷酸（PDRN）复合溶液已完成全部临床受试者入组，预 计于今年下半年提交上市申请，届时将向国内首个获批上市的PDRN三类械发起冲击。 图1.PDRN的化学 结构（图源：Cardiovascular &Hematological） 事实上，作为再生领域的"液体黄金"，PDRN近些年一直备受市场关注，目前参与布局的国内企业已超过20家，这其中 不乏华熙生物、江苏吴中、华东医药、复星医药等行业巨头。而之所以会如此，关键还是在于其功效，因为具有刺激胶 原蛋白和弹力纤维增生的能力，PDRN在修复、抗衰老以及改善肤色肤质等方面都有极大的应用价值，再加上其碱基组 成与人类DNA相似度高达98%，因此不会引起明显的免疫反应，产品安全性极高。 不过到目前为止，国内还尚无PDRN溶液三类医疗器械产品获批上市，现有产品都是通过进口化妆品备案进行销售。所 ...