中经记者苏浩卢志坤北京报道 2018年11月，海创药业自主研发的高尿酸血症和痛风1类新药HP501缓释片获得国家药监局颁发的《临 床试验通知书》。公司满怀希望地宣布，这款具有自主知识产权的URAT1抑制剂将为中国1.3亿高尿酸 血症患者带来新希望。 然而，近七年后，2025年8月13日，海创药业在发布年中财报的同时宣布了一则消息：拟暂停HP501项 目的研发推进。此时，该项目已投入募集资金8111.25万元。 决定背后的原因是残酷的市场竞争：国内已有药企针对URAT1靶点的产品获批上市，并有多项围绕该 靶点的Ⅲ期临床研究正在进行。 8月22日，海创药业方面在接受《中国经营报》记者采访时表示，募投项目子项目调整是基于公司实际 情况并结合当前市场竞争格局、行业发展趋势等多重因素决定的。上述调整将更好地维护公司和广大投 资者的利益，符合公司的长远发展及规划。不会对公司当期经营业绩产生重大影响，不存在损害股东利 益的情形。 从临床到落寞 据了解，HP501是海创药业自主研发的小分子化学创新药，为尿酸盐阴离子转运体1（URAT1）抑制 剂。临床前研究结果显示，其生物活性优于同类药物，展现了优良的药代动力学和毒理学性质。 ...

Core Insights - Shenzhen Qianhai Taikang Hospital successfully held a forum on high-quality development in the health ecosystem, marking its first anniversary and establishing three specialized treatment centers [1][3] Group 1: Establishment of Specialized Centers - The hospital officially established three specialized treatment centers: the Cardiothoracic Center, the Shoulder Joint Center, and the Cartilage Repair Center, which are crucial for promoting high-quality development [3][6] - The Cardiothoracic Center is led by Professor Wang Zhiping, who has performed over 5,000 heart surgeries and is recognized for pioneering advanced cardiac techniques in Guangdong [5][6] - The Shoulder Joint Center focuses on advanced surgical techniques such as Latarjet and reverse total shoulder arthroplasty, while the Cartilage Repair Center emphasizes cutting-edge technologies for cartilage damage repair [8] Group 2: Strategic Cooperation with Sun Yat-sen University First Affiliated Hospital - The hospital deepened its strategic cooperation with Sun Yat-sen University First Affiliated Hospital by appointing several leading experts as consultants for various medical centers [9][12] - Over 230 experts from Sun Yat-sen University have provided support through regular consultations and surgeries, significantly enhancing the hospital's capabilities [12] Group 3: Achievements and Patient Care - In its first year, the hospital has treated over 70,000 patients, including more than 3,000 from Hong Kong, Macau, and foreign nationals, and completed over 1,100 surgeries, with over 70% being complex procedures [13] - The hospital aims to provide high-quality medical services with a focus on patient comfort, including the establishment of a "pain-free hospital" and the integration of smart hospital technologies [15]