Summary of Haohai Biology Conference Call Company Overview - **Company**: Haohai Biology - **Date**: September 18, 2025 Key Points Industry and Company Performance - **Revenue Decline**: Haohai Biology's revenue for the first half of 2025 decreased by 34% year-on-year, primarily due to changes in VAT policy affecting hyaluronic acid products, resulting in a profit reduction of approximately 30 million yuan [2][3] - **Overall Revenue**: The company achieved a revenue of 1.304 billion yuan in the first half of 2025, a year-on-year decline of 7% but a quarter-on-quarter increase of about 11% [3] - **Net Profit**: The net profit attributable to shareholders was 210 million yuan, down 10% year-on-year, but up 34% quarter-on-quarter [3] Business Segment Performance - **Aesthetic Medicine Segment**: - Revenue decreased by 9% year-on-year, with hyaluronic acid sales down 17% [2][4] - Human epidermal growth factor sales increased by 14% [2] - High-end hyaluronic acid product "Haimi" saw sales growth exceeding double digits, now accounting for over 40% of the segment [2][7] - **Ophthalmology Segment**: - Revenue decreased by 20% year-on-year, but sales of preloaded aspheric intraocular lenses increased by 74% [2][4] - High oxygen permeability orthokeratology lenses saw an 86% increase in sales [2][5] - **Surgical Segment**: - Revenue grew by 60%, with innovative hemostatic product "Kangrui Gel" contributing 44 million yuan [2][5] - New anti-adhesion surgical products performed well, achieving 40 million yuan in sales shortly after launch [2][24] Product Development and Market Strategy - **High-End Product Focus**: The company is focusing on exporting high-end products, with preparations for "Haimi" and "Haimi Yuebai" underway [10] - **New Product Lines**: The company is expanding its aesthetic medicine offerings, including dermal fillers and light therapy devices, with some products receiving FDA certification [11][12] - **Technological Advantages**: "Haimi" utilizes a unique cross-linking process for smooth injection, while "Haimi Yuebai" employs amino acid cross-linking for safety and effectiveness [9] Market Challenges and Responses - **Impact of VAT Policy**: The adjustment of VAT from 3% to 13% on hyaluronic acid and chitosan products is expected to impact profits throughout 2025, but no similar effects are anticipated in 2026 [2][5] - **Competitive Landscape**: The OK lens segment faced challenges due to competition from new products like defocus frame glasses, leading to a decline in sales [20][21] - **Price Pressure**: The company is increasing R&D investment in mid-to-high-end products to counteract potential price pressures from upcoming procurement policies [15] Future Outlook - **Performance Expectations**: The company remains optimistic about future growth despite current economic uncertainties, focusing on steady marketing efforts and product development [26] - **Market Share Potential**: The domestic multifocal intraocular lens market share is expected to increase due to price adjustments in procurement policies [16] Additional Insights - **Sales of Human Epidermal Growth Factor**: This product has seen significant growth due to its application in aesthetic medicine, with sales increasing since 2024 [13] - **Surgical Product Innovations**: The innovative hemostatic product "Kangrui Gel" has entered the Shanghai medical insurance directory, with plans to expand into other provinces [25] This summary encapsulates the key insights from Haohai Biology's conference call, highlighting the company's performance, strategic focus, and market challenges.

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性 或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部份內容而產生或因依 賴該等內容而引致的任何損失承擔任何責任。 Shanghai Haohai Biological Technology Co., Ltd.* 上海昊海生物科技股份有限公司 （於中華人民共和國註冊成立的股份有限公司） （股份代號：6826） 海外監管公告 本公告乃由上海昊海生物科技股份有限公司（「本公司」）根據《香港聯合交易所有 限公司證券上市規則》第13.10B條的規定刊發。 茲載列本公司在上海證券交易所網站刊登之《上海昊海生物科技股份有限公司 2025年半年度報告》，僅供參考。 承董事會命 上海昊海生物科技股份有限公司 主席 侯永泰 中國上海，2025年8月22日 於本公告日期，本公司之執行董事為侯永泰博士、吳劍英先生、陳奕奕女士及唐 敏捷先生；本公司之非執行董事為游捷女士、黃明先生及魏長征先生；及本公司 之獨立非執行董事為沈紅波先生、姜志宏先生、蘇治先生及楊玉社先生。 * 僅供識別 上海昊海生物科技股份有限公司2025 年半年度报告 公司代码 ...

Group 1 - The core viewpoint of the articles highlights the financial performance of Haohai Biological Technology for the first half of 2025, showing a decline in revenue and profit compared to the previous year [1][3] - The company's revenue for the reporting period was approximately RMB 1.293 billion, representing a year-on-year decrease of about 7.48% [1] - The profit attributable to ordinary shareholders was approximately RMB 211 million, down about 10.29% from the same period in 2024, with basic earnings per share at RMB 0.91 and an interim dividend of RMB 0.40 per share [1] Group 2 - The company faced challenges due to the implementation of national centralized procurement policies and a sluggish domestic consumption market, leading to a significant decline in the ophthalmology product line revenue, which decreased by approximately RMB 83.51 million, or 18.57% year-on-year [1] - The revenue from the medical beauty and wound care product line also saw a decline of approximately RMB 58.55 million, or 9.27%, primarily due to a temporary decrease in domestic demand for the first and second generation hyaluronic acid products [1] - Conversely, the revenue from the anti-adhesion and hemostatic product line increased by approximately RMB 41.10 million, or 59.68%, mainly due to the inclusion of the "Kangrui Gel" product in the Shanghai Municipal Biopharmaceutical "New and Excellent Drug and Medical Device" product catalog [2]

报告期内，该集团紧密围绕医美、眼科、骨科、防黏连及止血四大核心业务板块，积极应对外部环境的 机遇与挑战，持续深化产品创新、市场拓展和精益管理，集团整体经营继续保持了稳健发展态势。报告 期内，受到国家集采政策逐步落地实施以及国内消费市场出现疲态等因素影响，集团眼科产品线整体收 入较2024年同期下降约人民币8351万元，降幅约18.57%。报告期内，集团医疗美容与创面护理产品线 的收入较2024年同期下降约人民币5855万元，降幅约9.27%，主要是集团第一代和第二代玻尿酸产品受 到国内消费需求阶段性减少的影响，收入下降较为明显。 另外，根据国家税务总局《关于生物製品适用增值税政策执行口径》的要求，下属子公司上海其胜所生 产的相关产品不再被认定为适用增值税简易办法徵收率计算的生物制品，增值税率由3%调整为13%， 由于集团无法通过调整含税销售价格的方式消化上述税率调整的影响，导致报告期内相关上海其胜产品 的扣税后销售单价及收入有所下降。报告期内，集团防黏连及止血产品线收入较2024年同期增长约人民 币4110万元，增幅约59.68%，主要是集团"康瑞胶"产品于2024年12月被纳入《上海市生物医药"新优药 械" ...

Core Viewpoint - The company reported a decline in revenue and profit for the first half of 2025, attributed to external market challenges and regulatory changes affecting product pricing and demand [1][2]. Financial Performance - The company recorded a total revenue of approximately RMB 1.293 billion, a year-on-year decrease of about 7.48% [1]. - Research and development expenses amounted to approximately RMB 98.4 million, down about 21.53% year-on-year, representing 7.61% of total revenue [1]. - Profit attributable to ordinary shareholders was approximately RMB 211 million, a decline of about 10.29% year-on-year, with basic earnings per share at RMB 0.91 [1]. Business Segments - The company focuses on four core business segments: medical aesthetics, ophthalmology, orthopedics, and anti-adhesion & hemostasis, and has been actively responding to market opportunities and challenges [2]. - Revenue from the ophthalmology product line decreased by approximately RMB 83.51 million, a decline of about 18.57% compared to the same period in 2024, influenced by national procurement policies and a sluggish domestic consumption market [2]. - Revenue from the medical aesthetics and wound care product line fell by approximately RMB 58.55 million, a decrease of about 9.27%, primarily due to reduced domestic demand for the first and second generation hyaluronic acid products [2]. Product Innovations and Market Developments - The anti-adhesion and hemostasis product line saw revenue growth of approximately RMB 41.1 million, an increase of about 59.68%, mainly due to the inclusion of the "Kangrui Gel" product in the Shanghai biopharmaceutical "New and Excellent Drug and Device" product directory [3]. - The inclusion in the directory allows the product to access a green channel for public hospital admission in Shanghai and prioritize recommendations for Shanghai medical insurance negotiations, enhancing market access and patient willingness to pay [3].