智通财经记者 岳怀让 据深圳医学科学院官网消息，1月25日，深圳医学科学院颜宁、黄健和范潇团队联合北京大学宋晨团队 在Vita首期杂志上发表了题为"Open-state structure of veratridine-activated human Nav1.7 reveals the molecular choreography of fast inactivation"的文章。 消息提到，值得关注的是，该研究于2025年11月18日率先发表于"浪淘沙预印本平台"，成为该平台上线 后的首篇论文，迄今累计浏览量已近8000人次，全文下载超2000次。随后，论文经严格同行评议，正式 发表于由生命科学开放联盟联合建设的生命科学与生物医学领域高水平国际期刊Vita，并成为该期刊首 期发表的重要成果之一。 这一从预印本平台快速公开到顶级期刊正式发表的完整传播链条，生动体现了Vita期刊"零OA费用、回 归学术本源"的办刊理念，并通过浪淘沙平台实现了科研成果的即时开放共享，完美践行了"全网免费即 时预览+严格同行评议+期刊发表"的创新传播模式。该模式在兼顾传播效率与学术公信力的同时，有效 本 期 编 辑 邹姗 消息介 ...

据深圳医学科学院官网消息，1月25日，深圳医学科学院颜宁、黄健和范潇团队联合北京大学宋晨团队 在Vita首期杂志上发表了题为"Open-state structure of veratridine-activated human Nav1.7 reveals the molecular choreography of fast inactivation"的文章。 消息提到，值得关注的是，该研究于2025年11月18日率先发表于"浪淘沙预印本平台"，成为该平台上线 后的首篇论文，迄今累计浏览量已近8000人次，全文下载超2000次。随后，论文经严格同行评议，正式 发表于由生命科学开放联盟联合建设的生命科学与生物医学领域高水平国际期刊Vita，并成为该期刊首 期发表的重要成果之一。 这一从预印本平台快速公开到顶级期刊正式发表的完整传播链条，生动体现了Vita期刊"零OA费用、回 归学术本源"的办刊理念，并通过浪淘沙平台实现了科研成果的即时开放共享，完美践行了"全网免费即 时预览+严格同行评议+期刊发表"的创新传播模式。该模式在兼顾传播效率与学术公信力的同时，有效 提升了研究成果的可见度与影响力，充分展示了"自主平 ...

Core Viewpoint - The launch of the domestic preprint platform "Langtaosha" marks a significant step for China's life sciences sector, enabling independent and secure management of research data and academic dissemination, while addressing the challenges posed by international publication systems [1][2]. Group 1: Platform Overview - "Langtaosha" is a preprint platform developed collaboratively by Shenzhen Medical Academy, Shenzhen Bay Laboratory, Tsinghua University, and Westlake University, aimed at enhancing the efficiency and safety of academic communication in China [1][2]. - The platform allows researchers to publish their findings without incurring publication fees, contrasting with the traditional Open Access (OA) model that often requires authors to pay article processing charges (APC) [2][3]. Group 2: Market Context - The global academic publishing market is predominantly controlled by developed countries, with major players like Elsevier and Springer dominating the landscape, leading to over 90% of SCIE papers from Chinese scientists being published in foreign journals [2][3]. - In 2023, Chinese authors paid a total of $750 million in APCs, reflecting a 23% annual growth rate, which highlights the financial burden on researchers and the need for alternative publishing avenues [3]. Group 3: Benefits of Preprint Platforms - Preprint platforms like "Langtaosha" facilitate rapid dissemination of research findings, allowing for immediate feedback and collaboration across disciplines, thus enhancing the overall quality and impact of research [4][5]. - The introduction of blockchain technology in "Langtaosha" ensures transparency and traceability of research records, which is crucial for maintaining academic integrity and prioritizing original contributions [4]. Group 4: Future Development and Recommendations - Experts suggest that the development of preprint platforms in China is still in its exploratory phase and requires improved top-level design, institutional norms, and academic evaluation systems to support high-level scientific independence [6][7]. - Recommendations include establishing a national certification system for preprint platforms, defining qualification criteria, and integrating preprints into existing research management frameworks to enhance their credibility and acceptance [6][7].

摘要 ： 学术出版的高额费用已成全球科研人员的共同负担，而中国新推出的《Vita》期刊正试图打破这 一模式。 特别提示 微信机制调整，点击顶部"仪器信息网" → 右上方"…" → 设为 ★ 星标，否则很可能无法看到我 们的推送。 日前，从西湖大学获悉，由高等教育出版社主办、西湖大学牵头的生命科学与生物医学领域顶 级国际期刊《Vit a》将于2 0 2 6年春季正式亮相。该期刊由李党生担任主编，施一公担任共同主 编。 《Vit a》定位为国际高水平学术平台，坚持开放获取模式，但明确 不向作者收取任何版面费或 论文处理费 。这一政策直面当前全球科研人员面临的发表负担：有统计显示，2 0 2 4年中国学 者共支付了约9 . 0 9亿美元国际论文版面费。 期刊名"Vit a "源自拉丁语"生命"，寓意跨越国界的学术胸怀。目前，其国际刊号已获批，专家 咨询委员会已吸纳近百位国内外顶尖科学家，首批原创论文正处于最终审核阶段，预计2 0 2 6年 第一季度在线发布，纸质版将于6月出版。 同时，与之联动的" 浪淘沙预印本平台 "也已上线，为科研成果提供快速分享渠道。 《Vit a》的创办是对我国科研现实需求的回应。随着中国在 ...

Core Insights - The article discusses the launch of the LangTaoSha Preprint Server, a collaborative open science platform aimed at enhancing academic communication in the life sciences field [3][4]. - The platform is established by Shenzhen Medical Academy, Shenzhen Bay Laboratory, Tsinghua University, Westlake University, and other leading institutions, focusing on rapid dissemination of research findings prior to formal peer review [3]. - The introduction of blockchain technology ensures the integrity and traceability of scientific records by generating unique, immutable timestamps and encrypted certificates for each published paper [3]. Group 1: Platform Overview - The LangTaoSha Preprint Server officially launched in November 2025, providing a reliable and efficient environment for researchers [3]. - The platform has already published 11 research papers, including two from the team led by Academician Yan Ning [4]. - The platform aims to integrate AI-driven tools to streamline manuscript screening processes and improve manuscript quality [3]. Group 2: Research Highlights - The paper titled "Open-state structure of veratridine-activated human Nav1.7 reveals the molecular choreography of fast inactivation" focuses on capturing the open-state structure of the sodium channel Nav1.7 using veratridine [5][8]. - The research team identified two complexes of Nav1.7 with veratridine, revealing insights into the dual-mode regulatory mechanism of veratridine on sodium channels [9][11]. - Another paper, "High-throughput cryo-EM characterization and automated model building of glycofibrils via CryoSeek," introduces a new strategy combining cryo-electron microscopy with AI for discovering novel biological entities [12][13]. Group 3: Methodologies and Innovations - The CryoSeek methodology allows for high-throughput processing of cryo-EM data and automated modeling of glycan structures, establishing a workflow for reconstructing three-dimensional electron microscopy maps [14]. - The research team proposed a unified naming scheme for the fibers discovered through CryoSeek, which will aid in understanding glycan folding principles [14]. - A CryoSeek database has been created for data archiving and sharing, accommodating the large volume of structures obtained through this strategy [14].