Core Insights - Supramolecular technology is gaining significant attention in the cosmetics industry, focusing on "molecular structure" and "intelligent delivery" to enhance ingredient efficacy and stability [3][4][19] - Major international brands like L'Oréal and Shiseido, as well as local companies, are actively developing and applying supramolecular technology in their products [6][9][21] - The technology aims to address traditional active ingredient challenges, such as penetration, stability, and synergy, providing a new pathway for innovation in skincare [20][34] Industry Trends - The emergence of supramolecular technology reflects a broader trend in the cosmetics industry towards more effective, gentle, and intelligent products, driven by consumer demand for enhanced efficacy [19][20] - Companies are exploring various supramolecular pathways, including microcapsules, co-crystals, and self-assembly techniques, indicating a diverse approach to ingredient application [4][9] - The technology is seen as a response to the industry's need for differentiation and innovation, with brands focusing on structural optimization to enhance product performance [12][34] Product Development - L'Oréal's fourth-generation collagen cream and Shiseido's new products utilize supramolecular technology to improve ingredient absorption and efficacy [7][8] - Local brands like Fulejia and Marubi are also leveraging supramolecular techniques to enhance their product offerings, demonstrating the technology's widespread adoption [9][10] - The collaboration between companies and research institutions is crucial for advancing supramolecular technology, as seen in partnerships like that of Fulejia and Shenzhen Shanhai Innovation Technology [21][23] Scientific Foundation - Supramolecular technology is based on supramolecular chemistry, which studies the interactions between molecules through non-covalent bonds, allowing for dynamic and reversible assembly [14][15] - This approach differs fundamentally from traditional molecular modification, offering a modular and flexible method for creating complex structures [16][19] - The technology's potential for precise and intelligent delivery of active ingredients is being explored across various applications in the cosmetics sector [24][34] Challenges and Future Outlook - The industry faces challenges in establishing the stability and efficacy of supramolecular formulations in complex systems, which requires rigorous quality control and production processes [28][30] - Effective consumer education on supramolecular technology is essential, as understanding its benefits and applications can enhance market acceptance [30][32] - The future of supramolecular technology in cosmetics is promising, with potential applications extending beyond skincare to areas like hair care and fragrance, indicating a broad scope for innovation [35][36]

Core Viewpoint - PDRN is emerging as a key ingredient in the beauty industry, with significant market growth projected, driven by its established efficacy in medical aesthetics and innovative delivery technologies [5][6][10]. Market Overview - The global PDRN market was approximately 180 million in 2023 and is expected to grow to 3 billion by 2030, with a compound annual growth rate (CAGR) of 43% from 2024 to 2030 [5]. - As of June 2023, there are 3,894 brands using PDRN, with 16,901 products containing this ingredient, indicating rapid growth in its adoption [5]. Scientific Basis - PDRN has gained recognition in the medical aesthetics market, which has laid a solid consumer foundation for its transition into the broader beauty market [6]. - The ingredient's effectiveness is supported by advanced research in anti-aging, focusing on mitochondrial energy, chronic inflammation, and cellular autophagy [6][9]. Technological Innovation - Jumiya has developed a patented technology, "ball PDRN™," which compresses PDRN into nanometer-sized microspheres, enhancing its transdermal absorption and bioavailability [10][13]. - Experimental data shows that the penetration rate of ball PDRN™ into the dermis can reach 427.34% within one hour, overcoming previous limitations of large molecule PDRN [10]. Product Development - Jumiya's flagship product, the ball PDRN™ energy stick, has achieved over 30 million sales, establishing itself as a leading product in the PDRN market [16]. - The company has expanded its product line with the launch of the "ball PDRN™ super cream," which has also gained significant market traction [16][21]. Market Positioning - Jumiya is positioned as a leader in the PDRN skincare segment, having created a successful product ecosystem around this ingredient [14][22]. - The brand has effectively communicated the scientific benefits of PDRN to consumers, enhancing market understanding and acceptance [22][30]. Research and Development - Jumiya is actively involved in ongoing research to further explore PDRN's applications, including its effectiveness in post-procedure skin recovery [22][23]. - The company has established a strong research foundation, with a team recognized for significant contributions to the field, including over 200 SCI publications [25]. Industry Impact - Jumiya's innovations and market strategies are setting new standards in the beauty industry, particularly in the application of PDRN as a "super ingredient" [33]. - The brand's success is encouraging other domestic brands to invest in technological advancements and market strategies, potentially reshaping the competitive landscape [33].

Core Viewpoint - The article discusses the potential of domestic brands to lead the market in the precise anti-aging sector, particularly in the context of mitochondrial function and the innovative use of PDRN technology [2][3]. Group 1: Product Innovation - Baihong Group's brand Zhanmeya launched a new product, the "Ball PDRN Super Cream," which targets mitochondrial function for anti-aging [3][5]. - The product utilizes a proprietary technology called Mit o-S-PDRN™, which encapsulates PDRN in microspheres to enhance skin absorption and efficacy [13][14]. Group 2: Scientific Basis - Mitochondrial dysfunction is identified as a significant marker of aging, with studies indicating its role in skin aging processes [7][9]. - PDRN is highlighted as a key ingredient that can repair mitochondrial damage and enhance cellular energy production [12][15]. Group 3: Efficacy and Testing - The Ball PDRN Super Cream reportedly increases ATP levels in skin cells by 197.62%, significantly higher than similar products [19]. - Efficacy tests show that the cream can reduce crow's feet wrinkles by 41.87% and improve collagen production significantly over four weeks [20]. Group 4: Market Position and Strategy - Zhanmeya aims to establish itself as a leader in the PDRN market, having already achieved significant sales success with its previous product, the Ball PDRN Energy Stick [25][26]. - The brand is positioned to leverage its scientific research background to innovate further in the anti-aging skincare segment [24][28].