Core Insights - The beauty industry is undergoing a technological transformation, with the integration of medical research driving value upgrades in cosmetics. This dual integration of medicine and beauty is defining a new competitive logic in the industry [3][6][24]. Industry Trends - The 20th China Dermatology Association (CDA) conference showcased over 10,000 dermatologists and more than 100 companies, including both domestic and international beauty brands, highlighting the industry's focus on scientific collaboration [3][4]. - The concept of "medical-research co-creation" emerged as a key theme, with brands actively participating in discussions on how to contribute to the skin science system, moving from mere users of research to active participants in scientific understanding and industry standards [7][24]. Brand Innovations - Winona, a brand known for its scientific foundation, showcased its "NUTE" principle at CDA 2025, which emphasizes clinical needs, unique mechanisms, technology empowerment, and credible evidence in product development [10]. - HBN, a domestic skincare brand, initiated the establishment of a group standard for "Cosmetic Efficacy Evidence Weight Assessment Guidelines," aiming to shift the industry from experience-driven to evidence-based competition [11][13]. - Estee Lauder's Clinique presented a white paper on the causes and distribution patterns of post-inflammatory hyperpigmentation, demonstrating the brand's commitment to scientific validation [14][16]. Research and Development - The integration of research and clinical application is evident in the initiatives taken by brands like Giant Bio and Zhenyan Bio, which are expanding the boundaries of medical-research co-creation through innovative collagen products and clinical studies [20][22]. - The collaboration between brands and medical experts is evolving, with companies like Ximu Yuan conducting extensive research on sensitive skin, showcasing a shift from being mere users of research to contributors to scientific inquiry [24][25]. Future Outlook - The CDA conference highlighted a significant shift in the beauty industry towards a more scientific and collaborative approach, with brands, medical institutions, and research organizations forming a new ecosystem that emphasizes shared data and mutual advancement [47][48]. - The focus on original ingredient research is becoming a core strategy for leading domestic brands, as they aim to differentiate themselves from homogenized competition [38][39].

Core Viewpoint - PDRN is emerging as a key ingredient in the beauty industry, with significant market growth projected, driven by its established efficacy in medical aesthetics and innovative delivery technologies [5][6][10]. Market Overview - The global PDRN market was approximately 180 million in 2023 and is expected to grow to 3 billion by 2030, with a compound annual growth rate (CAGR) of 43% from 2024 to 2030 [5]. - As of June 2023, there are 3,894 brands using PDRN, with 16,901 products containing this ingredient, indicating rapid growth in its adoption [5]. Scientific Basis - PDRN has gained recognition in the medical aesthetics market, which has laid a solid consumer foundation for its transition into the broader beauty market [6]. - The ingredient's effectiveness is supported by advanced research in anti-aging, focusing on mitochondrial energy, chronic inflammation, and cellular autophagy [6][9]. Technological Innovation - Jumiya has developed a patented technology, "ball PDRN™," which compresses PDRN into nanometer-sized microspheres, enhancing its transdermal absorption and bioavailability [10][13]. - Experimental data shows that the penetration rate of ball PDRN™ into the dermis can reach 427.34% within one hour, overcoming previous limitations of large molecule PDRN [10]. Product Development - Jumiya's flagship product, the ball PDRN™ energy stick, has achieved over 30 million sales, establishing itself as a leading product in the PDRN market [16]. - The company has expanded its product line with the launch of the "ball PDRN™ super cream," which has also gained significant market traction [16][21]. Market Positioning - Jumiya is positioned as a leader in the PDRN skincare segment, having created a successful product ecosystem around this ingredient [14][22]. - The brand has effectively communicated the scientific benefits of PDRN to consumers, enhancing market understanding and acceptance [22][30]. Research and Development - Jumiya is actively involved in ongoing research to further explore PDRN's applications, including its effectiveness in post-procedure skin recovery [22][23]. - The company has established a strong research foundation, with a team recognized for significant contributions to the field, including over 200 SCI publications [25]. Industry Impact - Jumiya's innovations and market strategies are setting new standards in the beauty industry, particularly in the application of PDRN as a "super ingredient" [33]. - The brand's success is encouraging other domestic brands to invest in technological advancements and market strategies, potentially reshaping the competitive landscape [33].

Core Viewpoint - The article discusses the potential of domestic brands to lead the market in the precise anti-aging sector, particularly in the context of mitochondrial function and the innovative use of PDRN technology [2][3]. Group 1: Product Innovation - Baihong Group's brand Zhanmeya launched a new product, the "Ball PDRN Super Cream," which targets mitochondrial function for anti-aging [3][5]. - The product utilizes a proprietary technology called Mit o-S-PDRN™, which encapsulates PDRN in microspheres to enhance skin absorption and efficacy [13][14]. Group 2: Scientific Basis - Mitochondrial dysfunction is identified as a significant marker of aging, with studies indicating its role in skin aging processes [7][9]. - PDRN is highlighted as a key ingredient that can repair mitochondrial damage and enhance cellular energy production [12][15]. Group 3: Efficacy and Testing - The Ball PDRN Super Cream reportedly increases ATP levels in skin cells by 197.62%, significantly higher than similar products [19]. - Efficacy tests show that the cream can reduce crow's feet wrinkles by 41.87% and improve collagen production significantly over four weeks [20]. Group 4: Market Position and Strategy - Zhanmeya aims to establish itself as a leader in the PDRN market, having already achieved significant sales success with its previous product, the Ball PDRN Energy Stick [25][26]. - The brand is positioned to leverage its scientific research background to innovate further in the anti-aging skincare segment [24][28].