以下文章来源于中国企业家杂志 ，作者胡楠楠 中国企业家杂志 . 重金押向重组胶原蛋白领域。 来源 ：中国企业家杂志 记者： 胡楠楠 编辑 ： 米娜 讲好企业家故事，弘扬企业家精神 钟睒睒花34亿元投资"重组胶原蛋白第一股"，有了新进展。 9月19日，北京证券交易所（简称"北交所"）上市公司锦波生物发公告称，公司向特定对象发 行股票申请已获受理。 重组胶原蛋白无疑是当下生物科技公司追逐的风口，被称为"黄金赛道"。据弗若斯特沙利文预 测，未来五年中国重组胶原蛋白市场将从2025年的585.7亿元，增长到2030年的2193.8亿 元，年复合增长率接近45%。 与此同时，钟睒睒也需为他的商业帝国，寻找新的增长点。 来源： 北交所官网 特定发行对象指的便是养生堂有限公司（简称"养生堂"）。养生堂为钟睒睒个人实控的公司， 也是上市公司农夫山泉的母公司。 据了解，锦波生物此次募资金额达20亿元，资金将用于人源化胶原蛋白FAST数据库与产品开 发平台，以及补充流动资金。这也是北交所迄今为止募资金额最大的现金定增计划。 此外，钟睒睒还通过养生堂旗下公司——久视管理咨询（杭州）合伙企业，以约14亿元购买了 锦波生物实际控制人杨 ...

Core Insights - The founder of Gu Yu, Wang Anning, announced a commitment to invest at least 2 billion yuan in research and development over the next decade [1] - The concept of "functional skincare" is gaining traction among consumers, who are increasingly focused on product ingredient transparency and scientific efficacy [1] - The functional skincare market has seen a significant increase in attention, with a 358% growth from 2021 to 2023, and the core user group expanding by 23% during the same period [1] Company Developments - Gu Yu recently launched a proprietary anti-aging ingredient, "Human-like Exosome HME," marking its third innovative ingredient with complete independent intellectual property rights [3][7] - The new ingredient is based on artificial exosome technology and aims to address anti-aging concerns, which are becoming a critical factor in consumer skincare choices [7][10] - Gu Yu's research and development efforts have led to significant advancements in the efficacy of its products, with the new ingredient showing a 17.43% reduction in wrinkle count after 14 days and a 26.61% reduction after 28 days [11] Market Position - Gu Yu has positioned itself as a leader among domestic skincare brands, surpassing international competitors and achieving a GMV of over 5 billion yuan in 2024 [14] - The brand has established a comprehensive R&D and manufacturing infrastructure, including a 3,000 square meter research center and multiple production facilities [15] - Gu Yu's focus on core technology and independent research has allowed it to create products that significantly outperform industry standards [14][15] Research and Innovation - The company emphasizes the importance of using Chinese technology to develop ingredients suitable for the Chinese skin type, having analyzed nearly 100,000 skin samples from Chinese women [16] - Gu Yu's proprietary technologies, such as "Melt Crystallization Purification" and "28-Nanometer Encapsulation Technology," have enhanced the purity and efficacy of its key ingredients [16] - The collaboration with Xiamen University to establish a joint research center will further enhance Gu Yu's capabilities in developing active ingredients for anti-aging and other applications [19]

Core Viewpoint - Swiss brand Cellcosmet views China as the most important market in Asia, highlighting its unique ability to integrate online and offline consumption effectively [4][6]. Company Insights - Cellcosmet specializes in developing skincare products with live cells and no chemical additives, being the first brand to design products based on different hormonal needs for men and women [4]. - The brand has participated in the China International Consumer Products Expo for five consecutive years since 2021 and has established a presence in various duty-free stores in Hainan, expanding its retail business into the taxed market [4][6]. - In 2024, Cellcosmet plans to open 125 retail points in China and aims to further increase its market share [4]. Market Trends - The high-end skincare market in China is expected to continue its diversification trend, with a growing focus on efficacy-driven skincare products [4][6]. - Consumers are increasingly prioritizing the actual clinical effects of products over branding and packaging, indicating a maturation of the market [6]. - The shift towards "professional efficacy consumption" reflects an enhancement in consumer awareness and a more competitive market focused on product effectiveness [6]. Technology and Innovation - Cellcosmet's proprietary technology, CellControl™, ensures that live cells remain viable until the product is fully used, achieving a live cell content of up to 30%, the highest in the industry [5]. - This technology is positioned as unmatched within the industry, promising genuine revitalization effects for the skin [5].

Core Insights - The demand for "visualized efficacy" in the skincare market is increasing, with CEMOY's new White Lotus Flower Essence Oil 2.0 becoming a focal point due to its "five major contour support points enhancement" [1][3] - The product ambassador, Zhang Xinyu, embodies elegance and resilience, promoting the skincare philosophy of "exploring orderly beauty and reshaping contour order" [1] Product Efficacy - Testing shows that the essence oil effectively improves five key facial contour support points after 28 days of continuous use, including the brow arch, eye corners, apple cheeks, nasolabial folds, and jawline [3] - Other facial wrinkles such as nasolabial lines, glabellar lines, neck lines, forehead lines, under-eye lines, crow's feet, and mouth corners also showed varying degrees of improvement [3] Ingredient and Technology Integration - The product contains 38% organic white lotus seed oil and is certified by the EU COSMOS organic standard, ensuring purity and effectiveness [3] - CEMOY's proprietary KLOGen™ technology revitalizes youth proteins, providing essential support to the skin [3] - The formula includes squalane, jojoba seed oil, and various effective ingredients such as plant-based retinol and peptides, combined with dual-directional permeation technology for rapid nutrient absorption and enhanced skin barrier resilience [3] Market Positioning - CEMOY's White Lotus Flower Essence Oil 2.0 is now fully launched, expected to inject new vitality into the skincare market with its significant effects and rare organic ingredients, supported by the image of Zhang Xinyu [3]

Core Viewpoint - The company, Fulejia, announced on September 23 that its products are primarily divided into two categories: medical devices and functional skincare products, featuring a diverse range of formulations including masks, waters, serums, lotions, sprays, single-use products, and eye masks [2] Group 1 - The company offers a wide variety of product forms, which enhances its market coverage [2] - The product categories include both medical devices and functional skincare, indicating a diversified product portfolio [2]

Group 1: Sales Performance - The company's sales channel optimization has shown significant progress, with a 86.68% increase in revenue from Q1 to Q2 2025, indicating a recovery trend that aligns with company expectations [1] - The lactose acid mask launched in August last year has performed very well in sales during the first half of 2025, meeting company expectations [2] Group 2: Product Structure and Development - The company's product range includes medical devices and functional skincare products, featuring various forms such as masks, essences, lotions, and sprays [1] - The company has a robust pipeline of research projects, with ongoing efforts to enhance R&D capabilities following the establishment of a new R&D center in Shanghai [2] Group 3: Online Sales Channels - JD.com has emerged as a strong online sales channel, with the company enhancing its collaboration with JD to diversify product offerings and implement new promotional strategies, resulting in notable growth on the platform [2] Group 4: Future Plans - The company plans to continue launching new products in the upcoming quarters, with specific details to be announced in future communications [2] - Dividend arrangements for the third quarter are still under consideration, with updates to be provided through official announcements [2]

Core Insights - OPELESIS, a domestic skincare brand, completed its Pre-A round financing at the beginning of this year, with investment from Shunwei Capital, co-founded by Lei Jun and Xu Dalai [1][10] - The brand focuses on light medical beauty skincare, emphasizing technological innovation, and has a research center in Switzerland [1] Financing and Investment - The recent financing will primarily support biomedical research and innovation [3] - Shunwei Capital has invested in over 600 startups since its inception in 2011, with 38 of those companies successfully going public [9] Product Development and Technology - OPELESIS has developed NEUBLOX, a botulinum-like peptide that inhibits dynamic wrinkles with an immediate anti-wrinkle efficiency exceeding 300% compared to ordinary neuropeptides [3][4] - The company has registered 20 products, including skincare and oral health products, with a price range from 12.9 to 549 yuan [6] Market Performance - The projected GMV for OPELESIS on Douyin in 2024 is between 75 million and 100 million yuan, with current GMV ranging from 25 million to 50 million yuan [9] - The brand heavily relies on influencer live-streaming for sales, with over 80% of sales coming from this channel [9] Strategic Partnerships - Following the success of NEUBLOX, OPELESIS has formed a strategic partnership with i+Med to develop injectable biomaterials as a Class III medical device [9] Industry Trends - The light medical beauty market in China has seen a 55% increase in user scale compared to three years ago, with consumers increasingly interested in complex skincare principles [9]

Group 1: Switzerland-China Economic Relations - Switzerland's actual investment in China increased by 37.2% in the first eight months of this year, second only to Japan [1] - The second round of negotiations for the upgrade of the China-Switzerland Free Trade Agreement took place in July, covering various topics including trade facilitation and economic cooperation [1] - Swiss companies are increasingly integrating into the Chinese market, with many small and medium-sized enterprises willing to enter and expand their local operations and R&D centers [1] Group 2: Performance of Swiss Companies in China - Logitech has experienced rapid growth in China over the past 15 years, with the Chinese market becoming a core driver of the group's growth [2] - Logitech established a dedicated R&D team for the Chinese market, allowing for tailored strategies and sufficient investment to support innovation [2] - Swiss skincare brand Reine has seen significant growth since entering China in 2013, with its performance ranking among the top three globally [3] Group 3: Strategic Investments and Market Positioning - Hexagon has made substantial investments in China, establishing its largest single market presence, with a new headquarters in Shenzhen [4] - Hexagon views China as a global R&D center, leveraging local market demands to enhance product development and service optimization [5] - Sonova's establishment of a China headquarters reflects the country's strategic importance, with significant contributions to global business innovation [6] Group 4: Innovation and Market Adaptation - Companies are adapting their products and strategies to meet the fast-changing demands of the Chinese market, with local insights driving global product development [5][6] - The rapid evolution of consumer preferences in China, particularly in gaming and beauty products, is prompting companies to innovate and adjust their offerings accordingly [6] - Swiss companies are leveraging China's large population for clinical research and product optimization, benefiting both local and global markets [6]

Group 1 - The company, Betaini, has received three recognitions in the field of sustainable development, including being selected for the "Top 100 ESG Best Practices of Chinese Listed Companies 2025" and winning the "2025 China Listed Company Yinghua Award - A-share ESG Demonstration Case" [1][2] - Betaini is positioned as a skin health internet + big health industry group and ranks first in the sales of functional skincare products in China, demonstrating strong market leadership and commitment to corporate governance, environmental protection, and social responsibility [1][2] - The company has achieved a AAA ESG rating from Huazheng and has been recognized as an "Excellent ESG Practice Case" and "Best Practice in Investor Relations Management" by the China Association of Listed Companies [1][2] Group 2 - The three recognitions highlight Betaini's value as an industry benchmark in disclosure and practice, showcasing its evolution from a disclosure pioneer to a systematic model [2] - Betaini has published ESG reports for four consecutive years, aligning with international standards and transforming policy guidance into corporate actions, thus becoming a significant force in the sustainable transformation of Chinese enterprises [2] - The company's sustainable practices are integrated into its R&D, production, and branding, with initiatives such as a biodiversity protection project in Yunnan and innovative packaging that reduces plastic use by 39% [2][3] Group 3 - Betaini's ESG actions are driven by both scientific research and cultural values, with successful registration of 17 new cosmetic raw materials derived from Yunnan's biodiversity, contributing over 10 billion yuan to the industry chain in 2024 [3] - The "Weixiao Sunshine Program" has been protecting skin health in high UV regions for ten years, alongside projects focused on intangible cultural heritage and rural education, reflecting the company's deep-rooted value of giving back to society [3]

Core Idea - The company Gu Yu has launched the "Rainwood Symbiosis" project, which combines recycling, regeneration, and public welfare, transforming used skincare product caps into new desks for schools in need [1][4][10]. Group 1: Project Overview - In 2024, Gu Yu partnered with Ai Huishou to initiate the first phase of the "Rainwood Symbiosis" project, successfully creating a closed-loop model of recycling and public welfare [1]. - The project aims to recycle patented wooden caps from skincare products, which are then processed and transformed into new desks for schools, specifically benefiting students in rural areas [1][4]. Group 2: Impact on Education - In September 2025, 220 sets of desks made from recycled wooden caps were delivered to Zhangcheng Primary School in Ningxia, enhancing the learning environment for local children [5][7]. - The desks not only serve as new learning tools but also act as tangible examples of environmental education for the students [5][10]. Group 3: Community Engagement - The project has engaged over 50,931 consumers, resulting in the recycling of 4,428.7 kilograms of plastic bottles, which has significantly reduced carbon emissions [15]. - Gu Yu's initiative has fostered a connection between urban consumers and rural students, promoting a sense of community and shared responsibility for the environment [10][18]. Group 4: Educational Activities - Alongside the desk donation, Gu Yu organized educational activities, including skin health science classes and creative art sessions, to further enrich the students' learning experiences [10][12]. - These activities not only provided knowledge about skin health but also encouraged creativity and environmental awareness among the children [10][12]. Group 5: Future Commitment - Gu Yu emphasizes its commitment to corporate social responsibility, aiming to continue its efforts in promoting cultural heritage, rural revitalization, social welfare, and environmental sustainability [20][21]. - The company envisions that the impact of the "Rainwood Symbiosis" project will extend beyond material benefits, fostering a culture of care and responsibility towards the environment and community [18][21].