Investment Rating - The report maintains a positive outlook on the pharmaceutical industry, highlighting investment opportunities in AI healthcare and innovative drugs [1]. Core Insights - The pharmaceutical sector index increased by 1.13% this week, outperforming the CSI 300 index by 0.25 percentage points, ranking 17th in industry performance [14]. - Year-to-date, the pharmaceutical industry has risen by 7.81%, surpassing the CSI 300 index by 9.36 percentage points, ranking 5th [14]. - The current valuation level (PE-TTM) for the pharmaceutical industry is 28.24 times, with a premium of 86.84% relative to the entire A-share market [19]. - The best-performing sub-sector this week was vaccines, which rose by 2.9%, while the top three sub-sectors year-to-date are chemical preparations, raw materials, and other biological products, with increases of +21.3%, +20.4%, and +16.1% respectively [28]. Summary by Sections Investment Strategy - The report emphasizes the acceleration of AI healthcare development and investment opportunities, with over 830 hospitals in China completing the localization of DeepSeek-R1, marking a new phase in medical intelligence [15]. - Continuous attention is recommended for innovative drugs, especially following the ASCO 2025 conference, where over 70 research abstracts led by Chinese scholars were presented [16]. Market Performance - The pharmaceutical industry has shown strong performance, with a notable increase in the number of stocks with positive returns, totaling 330, while 150 stocks experienced declines this week [29]. - The report lists the top gainers and losers in the pharmaceutical sector, with 易明医药 (Yiming Pharmaceutical) leading with a gain of +33.1% and *ST龙津 (ST Longjin) facing a decline of -36.3% [29]. Recent News and Policies - The report highlights the ongoing trend of AI integration in healthcare, with significant advancements in clinical decision support systems and AI-assisted diagnostics [15]. - It also notes the importance of focusing on drug development that is patient-centered and clinically valuable, aligning with the broader themes of innovation and internationalization in the pharmaceutical industry [16].

Policy Developments - The National Healthcare Security Administration has revised the medical price and procurement credit evaluation system to combat commercial bribery and encourage integrity among pharmaceutical companies [2][3] - The revised system aims to increase the cost of dishonesty for companies and promote compliance, quality improvement, and effective market participation through collective procurement and national negotiations [2][3] Industry Updates - The internal whistleblower reward system for drug and medical device quality safety has been announced, incentivizing individuals who provide clear evidence of violations that lead to administrative penalties or criminal prosecution [4] - A notification has been issued to promote pain relief services during childbirth across various medical institutions, with goals set for 2025 and 2027 to ensure comprehensive service availability [5] Company News - Puluo Pharmaceutical has received approval for the listing application of Succinic Acid Desvenlafaxine, a third-generation antidepressant for treating major depressive disorder [7] - China Pharmaceutical has obtained a drug registration certificate for Sulfhydryl Clopidogrel Tablets, aimed at secondary prevention of atherosclerotic thromboembolic events in specific patient groups [8] - Shanghai Sipurei Pharmaceutical Technology has completed over 200 million RMB in angel round financing, with funds allocated for preclinical and early clinical development [11] - Kelun Pharmaceutical's subsidiary plans to raise approximately 1.943 billion HKD through a share placement to support product development and operational needs [12] - Merck KGaA has entered a strategic partnership with Zai Lab to commercialize a recombinant human thyroid-stimulating hormone in mainland China [14] - China National Pharmaceutical Group has established a technology innovation research institute with a registered capital of 1 billion RMB, focusing on various research and development activities [15] Management Changes - Tongrentang Technology announced the resignation of its chairman and general manager due to work changes, indicating potential shifts in company leadership [17]