间苯三酚三甲醚主要用于制备间苯三酚注射液，其主要用于治疗消化系统和胆道功能障碍引起的急性痉 挛疼痛;急性痉挛性尿道、膀胱、肾绞痛;及妇科痉挛性疼痛。诚如本公司日期为2024年8月27日的公告 所载，本集团已取得国家药监局有关间苯三酚注射液的药品生产注册批件。 盐酸多巴酚丁胺主要用于制备盐酸多巴酚丁胺注射液，其主要用于器质性心脏病时心肌收缩力下降引起 的心力衰竭，包括心脏直视手术后所致的低排血量综合症。 石四药集团(02005)发布公告，本集团的间苯三酚三甲醚及盐酸多巴酚丁胺已获中国国家药品监督管理 局(国家药监局)批准登记成为在上市制剂使用的原料药。 ...

盐酸多巴酚丁胺主要用于制备盐酸多巴酚丁胺注射液，其主要用于器质性心脏病时心肌收缩力下降引起 的心力衰竭，包括心脏直视手术后所致的低排血量综合症。 间苯三酚三甲醚主要用于制备间苯三酚注射液，其主要用于治疗消化系统和胆道功能障碍引起的急性痉 挛疼痛;急性痉挛性尿道、膀胱、肾绞痛;及妇科痉挛性疼痛。诚如本公司日期为2024年8月27日的公告 所载，本集团已取得国家药监局有关间苯三酚注射液的药品生产注册批件。 智通财经APP讯，石四药集团(02005)发布公告，本集团的间苯三酚三甲醚及盐酸多巴酚丁胺已获中国国 家药品监督管理局(国家药监局)批准登记成为在上市制剂使用的原料药。 ...

间苯三酚三甲醚主要用于制备间苯三酚注射液，其主要用于治疗(i)消化系统和胆道功能障碍引起的急性 痉挛疼痛；(ii)急性痉挛性尿道、膀胱、肾绞痛；及(iii)妇科痉挛性疼痛。集团已取得国家药监局有关间 苯三酚注射液的药品生产注册批件。 格隆汇2月9日丨石四药集团(02005.HK)公告，集团的间苯三酚三甲醚及盐酸多巴酚丁胺已获中国国家药 品监督管理局("国家药监局")批准登记成为在上市制剂使用的原料药。 盐酸多巴酚丁胺主要用于制备盐酸多巴酚丁胺注射液，其主要用于器质性心脏病时心肌收缩力下降引起 的心力衰竭，包括心脏直视手术后所致的低排血量综合症。 ...

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告之內容概不負責，對其準確 性或完整性亦不發表任何聲明，並明確表示，概不會就因本公告全部或任何部份內容而產生 或因倚賴該等內容而引致之任何損失承擔任何責任。 本公告為本公司自願發佈，目的是使股東及潛在投資者瞭解本集團最新業務發展情況。 石四藥集團有限公司（「本公司」，連同其附屬公司，「本集團」）董事局（「董事局」）欣然公告， 本集團的間苯三酚三甲醚及鹽酸多巴酚丁胺已獲中國國家藥品監督管理局（「國家藥監局」）批 准登記成為在上市製劑使用的原料藥。 間苯三酚三甲醚主要用於製備間苯三酚注射液，其主要用於治療(i)消化系統和膽道功能障礙引 起的急性痙攣疼痛；(ii)急性痙攣性尿道、膀胱、腎絞痛；及(iii)婦科痙攣性疼痛。誠如本公司 日期為二零二四年八月二十七日之公告所載，本集團已取得國家藥監局有關間苯三酚注射液的 藥品生產註冊批件。 鹽酸多巴酚丁胺主要用於製備鹽酸多巴酚丁胺注射液，其主要用於器質性心臟病時心肌收縮力 下降引起的心力衰竭，包括心臟直視手術後所致的低排血量綜合症。 自願公告 產品開發的最新進展 承董事局命 執行董事兼公司秘書 周興揚 香港，二零二六年 ...

Core Viewpoint - Chengyi Pharmaceutical has received approval for its Palivizumab injection, marking a significant milestone in its drug development efforts and expanding its product line in the influenza treatment market [1][2] Group 1: Drug Approval and Market Position - The Palivizumab injection has been approved as a Class 3 chemical drug for the treatment of influenza A or B [1] - In 2023, the total sales of the four main influenza treatment drugs in the domestic market reached 11.405 billion yuan, with Oseltamivir holding the majority market share [1] - Palivizumab is recognized as the first innovative Class 1 anti-influenza drug approved in China, recommended in various influenza treatment guidelines [1] Group 2: Product Line Expansion and Financial Performance - Over the past year, Chengyi Pharmaceutical has launched multiple products in the formulation sector, continuously expanding its product line [2] - The company expects a net profit attributable to shareholders of 107 million to 119 million yuan for the first half of 2025, representing a year-on-year growth of 40% to 55%, primarily driven by the sales growth of joint-related drugs [2] - The company is also advancing its "Two Strong One Big Project" initiative in marine biomedicine, with a large-scale EPA fish oil production project underway, which is expected to become a core revenue driver alongside joint-related drugs [2]

Group 1 - The company held its fourth board meeting on April 28, 2025, where it approved changes to its accounting policies without requiring shareholder approval [1][6][40] - The change in accounting policy is due to the Ministry of Finance's issuance of Interpretation No. 18, which clarifies the reporting of warranty-related costs [1][3][4] - The new accounting policy will be implemented starting December 6, 2024, and aims to provide a more objective and fair representation of the company's financial status and operating results [1][5][4] Group 2 - The company has proposed to elect a new board of directors, consisting of nine members, including six non-independent directors and three independent directors [9][10][11] - The election of the new board is scheduled to be presented at the 2024 annual general meeting [9][10][11] - The company will hold a staff representative meeting on May 20, 2025, to elect one staff representative director [10] Group 3 - The company has received approval from the National Medical Products Administration for the marketing of the chemical raw material drug, Dobutamine Hydrochloride [34][36] - This approval allows the company to produce and sell the drug domestically, which is used in the treatment of cardiovascular diseases [34][36][37] - The company has invested approximately RMB 5.1982 million in the research and development of this raw material drug [37] Group 4 - The company has proposed a profit distribution plan, intending to distribute cash dividends of RMB 0.25 per share, totaling approximately RMB 79.42 million [99][102] - The proposed cash dividend represents 39.57% of the company's net profit attributable to shareholders for the year [102] - The profit distribution plan is subject to approval at the upcoming shareholder meeting [102][105] Group 5 - The company has decided to cancel its supervisory board, transferring its responsibilities to the audit committee of the board [109][110] - This decision aligns with recent amendments to the Company Law and aims to streamline governance [109][110] - The relevant rules and regulations will be revised accordingly to reflect this change [109][110]