Company Overview - 德镁医药 is an innovative pharmaceutical company focused on skin health, operating under 康哲药业. It specializes in prescription drugs and dermatological skincare products, with three products already on the market and several candidates in various clinical stages [1] Financial Performance - Revenue for 2023 reached RMB 472.56 million, a year-on-year increase of 23.2%, driven by a robust growth in prescription drugs and a significant surge in skincare products [2][3] - Prescription drug revenue was RMB 424.82 million in 2023, up 13.6% from RMB 374.04 million in 2022, accounting for 89.9% of total revenue [2] - Skincare product revenue skyrocketed by 404.4% to RMB 47.74 million in 2023, primarily due to successful e-commerce promotions [3] Profitability and Margins - The overall gross margin improved to 76.9% in 2023, up 6.8 percentage points from the previous year, with a significant reduction in net loss to RMB 5 million [5] - The gross margin for prescription drugs was 76.6%, while skincare products achieved a gross margin of 79.0% [5] - However, the gross margin is expected to decline to 63.5% in 2024 due to increased costs and pricing pressures from insurance adjustments [7][8] Debt Structure and Cash Levels - A debt-to-equity conversion in 2024 significantly improved the company's balance sheet, reducing liabilities from RMB 15.75 billion to RMB 1.54 billion [10] - Despite the reduction in debt, cash reserves remain tight, with only RMB 2.82 billion available at the end of 2024 [10] Competitive Advantages - 德镁医药 has the broadest coverage of skin disease indications in China, with nine conditions addressed, surpassing competitors [11] - Key products like 益路取 for psoriasis and 喜辽妥 for scar treatment have unique advantages, including insurance coverage and lack of direct competition [12][14] - The company benefits from a strong distribution network, leveraging 康哲药业's existing relationships with over 10,000 hospitals and 100,000 pharmacies [13] Industry Context - The Chinese skin treatment and care market was valued at RMB 76.4 billion in 2023, with a projected CAGR of 10.6% through 2035, driven by the high prevalence of chronic skin diseases [20] - The demand for dermatological skincare products is also increasing, with significant growth in e-commerce channels [20]

Company Dynamics - Kangzheng Pharmaceutical plans to spin off its subsidiary, Demai Pharmaceutical, which focuses on skin health, for independent listing on the Hong Kong Stock Exchange [3] - Kangzheng holds 90.8% of Demai's shares, with the remaining 9.2% held by employee incentive platforms [3] - The spin-off is expected to be executed through a distribution of shares to existing shareholders [3] Financial Performance - Demai Pharmaceutical's revenue from 2022 to 2024 is projected to be 384 million, 473 million, and 618 million respectively, totaling nearly 1.5 billion with a compound annual growth rate of 26.89% [4] - Despite revenue growth, Demai has reported losses of 55.17 million, 4.703 million, and 106 million over the same period, attributed to high sales and R&D expenses [4] - The company has successfully entered the skin-level skincare market, with related business revenue exceeding 10% of total revenue [3][4] Market Implications - No skin-level skincare companies have successfully listed on the Hong Kong Stock Exchange to date, making Demai's potential listing a significant milestone for the sector [4] - A successful listing would signal positive developments for the skin-level skincare industry in the capital market [4]

Core Viewpoint - Kangzheng Pharmaceutical is planning to spin off its subsidiary, Demai Pharmaceutical, which focuses on skin health, for independent listing on the Hong Kong Stock Exchange. This move raises questions about whether it is a strategic decision or an attempt to offload a loss-making entity [1][4]. Group 1: Spin-off Details - The spin-off will involve a distribution of 90.8% of Demai's shares to existing shareholders, with no new stock issuance for financing. This allows shareholders to directly hold shares of Demai and benefit from independent valuation premiums [1][2]. - Demai Pharmaceutical has shown revenue growth from 384 million yuan in 2022 to 618 million yuan in 2024, but its losses have also increased from 55.17 million yuan to 106 million yuan during the same period [2][3]. Group 2: Financial Performance - Demai's gross margin for prescription drugs is projected to decline from 76.6% in 2023 to 61.7% in 2024, contributing to an overall gross margin drop from 76.9% to 63.5% [2][3]. - The company's sales expense ratio has risen from 57.7% to 62.9%, with sales expenses reaching 388 million yuan in 2024, nearly matching its gross profit [2][3]. Group 3: Strategic Context - Kangzheng Pharmaceutical is facing significant performance pressure, with a revenue decline of 6.8% to 7.469 billion yuan and a net profit drop of 32.3% to 1.613 billion yuan in 2024. The decline is attributed to the impact of national procurement policies on key products [4][5]. - The spin-off aims to achieve three objectives: shedding the loss-making skin business, allowing Demai to raise capital independently, and enhancing the overall market valuation of the group by focusing on higher-margin areas [4][5]. Group 4: Market Landscape - The skin health market is projected to grow significantly, with an estimated market size of 254.9 billion yuan by 2035 and a compound annual growth rate exceeding 15% [4]. - However, Demai faces intense competition from stronger players in the skin health sector, and its reliance on generic products and high sales expenses raises concerns about sustainability [5].

Core Viewpoint - 德镁医药's parent company, 康哲药业, experienced a revenue decline of 6.8% last year and is attempting to reshape its growth momentum through a spin-off listing in Hong Kong [1] Group 1: Company Overview - 德镁医药 is an innovative pharmaceutical company focused on skin health, providing comprehensive solutions for skin disease patients from prevention to long-term care [1] - The company has achieved a significant position in the industry, ranking first in the number of skin disease indications covered by its products among Chinese innovative pharmaceutical companies in 2024 [2] Group 2: Financial Performance - 德镁医药's revenue has shown an upward trend, increasing from 384 million yuan in 2022 to 473 million yuan in 2023, and further to 618 million yuan in 2024 [3] - Despite revenue growth, the company recorded net losses of 55.17 million yuan, 4.7 million yuan, and 106 million yuan from 2022 to 2024, primarily due to high sales expenses for new product promotions and significant R&D investments [4] Group 3: Product and R&D Strategy - The company has a rich and differentiated product portfolio, with its main product pipeline covering various major skin diseases, including both marketed and clinical-stage candidates [5][6] - 德镁医药 employs a dual approach to R&D, collaborating with global pharmaceutical companies while also developing innovative drugs independently, such as CMS-D001, which is currently in Phase I clinical trials [7] Group 4: Commercialization and Market Presence - The company has strong commercialization capabilities, supported by a self-built team of over 650 professionals and a sales network that covers numerous hospitals, retail pharmacies, and major e-commerce platforms [8] Group 5: Market Challenges - The company faces potential risks in its IPO, including the lengthy and costly nature of innovative drug development, with uncertainties regarding regulatory approvals for its candidates [9] - The pharmaceutical industry is highly competitive, and 德镁医药 must timely launch competitive new products to avoid pricing pressures that could impact profits and market share [10] - Regulatory policies, such as centralized procurement and reimbursement policies, may affect product demand and commercialization success if products are not included in the medical insurance directory or if reimbursement levels are limited [11]