Industry Rating - Investment Rating: Recommended (Maintain) [1] Core Viewpoints - The chemical industry is expected to benefit from the anticipated interest rate cuts by the Federal Reserve, which may drive demand and support the recovery of the industry [2][4]. - The significant growth of chemical ETFs, from 2.2 billion to 15.7 billion, indicates a positive outlook for leading chemical companies and new material growth [4]. - The report emphasizes the importance of focusing on core chemical assets, which are expected to see profit and valuation recovery in the medium to long term [3][5]. Summary by Sections Investment Recommendations - Long-term value in white horse stocks is emphasized, with core chemical assets expected to experience profit and valuation recovery [3]. - Attention is drawn to leading chemical companies as potential investment opportunities due to their strong market positions and growth prospects [4][5]. Market Dynamics - The report highlights the impact of external factors such as the U.S. tariffs on Indian goods, which may improve the pesticide trade between the U.S. and China, benefiting companies like Yangnong Chemical and Runfeng Shares [4]. - The recent adjustments in real estate policies in Shanghai are expected to marginally improve demand for chemical products related to the real estate sector [4]. Price Trends - The report notes that chemical product prices and price spreads are currently at bottom levels, suggesting potential for price increases in the future [5]. - Specific price movements are tracked, such as the increase in Vitamin B3 and D3 prices due to supply tightness, and the upward trend in refrigerant prices driven by supply constraints [9][10]. Supply Chain Insights - The report discusses the supply-side changes in the ethylene industry due to force majeure events, which may lead to supply recovery in the sector [4]. - It also mentions the ongoing supply constraints in the refrigerant market due to quota management, which is expected to maintain high price levels [9]. Strategic Focus Areas - The report recommends focusing on leading companies in the chemical sector, such as Hengli Petrochemical, Rongsheng Petrochemical, and others, as they are likely to benefit from industry recovery and supply-side improvements [4][5]. - The emphasis is placed on the potential for strategic opportunities in the petrochemical sector as oil prices stabilize and supply-demand dynamics shift [5].

Core Findings - A team from the University of California, Irvine discovered that a combination of Vitamin B3 (niacinamide) and the active component in green tea, EGCG, can rejuvenate aging brain cells and effectively clear harmful protein accumulations associated with Alzheimer's disease [1][2] - The research published in the latest issue of "Aging Science" indicates that this combination significantly enhances the levels of GTP, a key energy molecule in brain cells, and improves the ability to clear β-amyloid proteins, which are characteristic of Alzheimer's disease [1][3] Mechanism of Action - The study utilized a gene-encoded fluorescent sensor named GEVAL to monitor GTP dynamics in neurons of aged Alzheimer's model mice, revealing a continuous decline in GTP levels with age, particularly in mitochondria, which severely impacts autophagy, the process of clearing damaged components [1] - Neurons treated with niacinamide and EGCG showed GTP levels restored to those of younger cells, leading to improved energy metabolism, activation of key proteins responsible for cellular transport, and efficient clearance of β-amyloid aggregates, thereby reducing oxidative stress associated with neurodegeneration [2] Implications for Treatment - The findings suggest that the combination of these two natural dietary supplements may serve as a new tool in combating cognitive decline and Alzheimer's disease [3]