苏州富士莱医药股份有限公司 投资者关系活动记录表 证券代码：301258 证券简称：富士莱 编号：20250825 | | √特定对象调研 | □分析师会议 | | --- | --- | --- | | 投资者关系活动 | □媒体采访 | √业绩说明会 | | 类别 | □新闻发布会 | □路演活动 | | | □现场参观 | □其他 | | | 线上参与富士莱 | 年半年度网上业绩说明会的投资者 2025 | | | 蒋维东 | 华福证券有限责任公司 | | | 温灵军 | 上海璞智投资管理有限公司 | | | 王瑞 | 上海海能投资 | | | 李尊 | 南京金友私募基金管理有限公司 | | | 曹新林 | 浙江大通骐楷投资管理有限公司 | | | 王焕 | 常熟银行 | | | 曹志平 | 粤佛私募基金管理(武汉)有限公司 | | | 陆懿晨 | 上海融义投资咨询有限公司 | | 参与单位名称及 | 梁游 | 华数数科 | | | 向红旭 | 尚诚资产管理 | | 人员姓名 | 魏鑫 | 北京橡果资产管理有限公司 | | | 颜丽红 | 旭为投资 | | | 应方 | 上海涌融私募基金管理有限公司 | ...

回顾过往，从灵魂砍价到高质量发展，中国创新药迎来高歌猛进的黄金十年。如今，从"中国制造"到"全球智造"，中国创新药企们正在重新定义全球医药产 业的游戏规则。 在这股浪潮中，作为中国创新药企的领军者，恒瑞医药自今年上半年成功赴港上市后，再次迎来他的高光时刻。在其赴港上市厚首份业绩成绩单中，核心指 标再创新高。 根据公告显示，2025上半年，公司营收、净利润双双大幅增长，创下历史新高。尤其引人注目的是，其创新药销售收入与对外授权收入占比突破60%，标志 着正式迈入高质量发展的"收获期"，转型升级全面提速。 亮眼数据的背后，是中国创新药从"跟跑"到"领跑"的质变，更是中国经济从规模扩张向质量跃升的核心密码——以创新为引擎、以国际化为路径，在全球价 值链重构中抢占制高点。 营收净利再创新高，迈入收获期 尽管面临医药行业政策持续调整与变革，恒瑞医药依然展现出强劲的业绩韧性，稳健穿越行业周期，持续引领创新转型。 从收入端看，公司坚定创新驱动，业绩实现高速增长。 创新转型的成效已在利润端清晰显现。2025年上半年，公司实现归母净利润44.5亿元，同比增长29.67%；净利率达到28.26%，同比提升3.05个百分点，创上 ...

上半年研发投入逾38亿元 创新药方面，恒瑞医药半年报显示，2025年上半年，公司创新药销售及许可收入为95.61亿元，占公司 营业收入比重的60.66%，其中创新药销售收入为75.70亿元。 业内人士表示，当前我国创新药相关企业已经实现从量变到质变的转化，逐渐从"跟跑者"到"引领者"。 创新药板块景气度有望持续，"创新+国际化"步伐逐渐加快，成为医药板块的核心方向。 恒瑞医药 恒瑞医药表示，瑞维鲁胺、达尔西利、恒格列净等创新药收入继续保持快速增长。艾瑞昔布、瑞马唑 仑、吡咯替尼及氟唑帕利等上市较早的创新药，随着上市后研究循证医学证据的逐步积累及新适应症的 持续获批，持续为公司销售收入贡献增量。 ● 本报记者 李梦扬 近日，恒瑞医药发布2025年半年度报告。2025年上半年，恒瑞医药实现营业收入157.61亿元，同比增长 15.88%；归属于上市公司股东的净利润44.50亿元，同比增长29.67%；经营性现金流净额达43.00亿元， 同比增长41.80%。上半年公司营收、净利及经营性现金流净额均创同期新高。记者梳理发现，截至目 前，百济神州、翰森制药等多家创新药企披露上半年业绩情况，创新药收入情况、研发管线进展 ...

8月20日，恒瑞医药（股票代码：600276.SH；01276.HK）发布2025年半年度报告。报告显示， 2025年上半年，公司实现营业收入157.61亿元，同比增长15.88%；归属于上市公司股东的净利润 44.50亿元，同比增长29.67%；经营性现金流净额达43.00亿元，同比增长41.80%。营收、净利及经 营性现金流净额均创往年同期新高，业绩进入爆发增长期。公司持续加大创新力度，维持较高的研 发投入，报告期内公司研发投入38.71亿元，其中费用化研发投入32.28亿元。 为了增强团队凝聚力及公司核心竞争力，充分发挥长效激励机制，恒瑞医药还同时公告将 回 购 1 0 亿 - 2 0 亿 元 的 股 份 ， 用 于 实 行 新 的 员 工 持 股 计 划 ， 2 0 2 5 年 激 励 规 模 不 超 过 1 4 0 0 万 股。 创新药销售引领业绩增长 对外许可成常态化业务 从业绩角度来看，持续的高强度研发投入加快公司转型升级步伐，公司迈入了创新药丰收 期，创新药收入持续提升。2 0 2 5年上半年公司创新药销售及许可收入9 5 . 6 1亿元，占公司 营业收入比重6 0 . 6 6%，其中创新药销 ...

Core Insights - The company reported a revenue of 15.76 billion yuan for the first half of 2025, representing a year-on-year growth of 15.88% [1] - The net profit attributable to shareholders reached 4.45 billion yuan, with a year-on-year increase of 29.67% [1] - Operating cash flow net amount was 4.30 billion yuan, showing a growth of 41.80% year-on-year [1] Revenue Breakdown - Sales and licensing income from innovative drugs amounted to 9.56 billion yuan, accounting for 60.66% of total revenue, with innovative drug sales reaching 7.57 billion yuan [1] - The company has seen rapid growth in revenue from innovative drugs such as Rivoceranib, Darsylin, and Henggrelizumab, which have gained clinical recognition [1] R&D Investments - R&D expenditure for the reporting period was 3.87 billion yuan, with 3.23 billion yuan classified as expensed R&D [1] - The company has advanced 15 self-developed innovative molecules into clinical stages, covering various disease areas including oncology and cardiovascular diseases [2] Product Approvals - Six first-class innovative drugs were approved for market launch during the reporting period, including injection of Rika single antibody and Sulfate Emamectin tablets [1] - The company received approvals for six new indications for existing innovative drugs, enhancing their market potential [1] Clinical Trials and Platforms - The company has five listing applications accepted by NMPA, with 10 projects in Phase III and 22 in Phase II clinical trials [2] - A new molecular model platform has been established, focusing on AI drug development and streamlining R&D processes [2] Licensing and Partnerships - The company received upfront payments of 200 million USD from Merck and 75 million USD from IDEAYA, contributing to revenue growth [3] - The company is enhancing its core competitiveness through a share buyback plan of 1 to 2 billion yuan for a new employee stock ownership plan [3]

Core Viewpoint - Heng Rui Medicine (600276) reported strong financial performance in the first half of 2025, with significant growth in revenue and net profit driven by innovative drug sales and licensing [2][4]. Financial Performance - The company achieved operating revenue of 15.76 billion yuan, a year-on-year increase of 15.88% [2]. - The net profit attributable to shareholders reached 4.45 billion yuan, reflecting a year-on-year growth of 29.67% [2]. Innovative Drug Development - Innovative drug sales and licensing revenue amounted to 9.56 billion yuan, accounting for 60.66% of total revenue, with sales revenue from innovative drugs at 7.57 billion yuan [4]. - Key innovative drugs such as Rivoceranib, Darsylin, and Hengriletin continued to show rapid growth, while older drugs like Arixtra and Pyrrolidine contributed to revenue through new indications [4]. - The company invested 3.87 billion yuan in R&D during the first half of the year, with a total R&D investment exceeding 48 billion yuan as of June 30 [4]. International Expansion - Heng Rui Medicine accelerated its internationalization efforts, with innovative drug licensing becoming a key growth driver [6]. - The company received upfront payments of 200 million USD from Merck and 75 million USD from IDEAYA, contributing to revenue growth [6]. - Strategic partnerships were established, including a collaboration with GSK for the development of up to 12 innovative drugs, with an upfront payment of 500 million USD and potential total payments of around 12 billion USD [6]. Hong Kong Listing - Heng Rui Medicine successfully listed on the Hong Kong Stock Exchange on May 23, raising a total of 11.4 billion HKD (approximately 1.5 billion USD), marking the largest IPO in the Hong Kong pharmaceutical sector in the past five years [7].

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性 或完整性亦不發表任何聲明，並明確表示概不就因本公告全部或任何部分內容所產生或因依賴 該等內容而引致的任何損失承擔任何責任。 Jiangsu Hengrui Pharmaceuticals Co., Ltd. 江蘇恒瑞醫藥股份有限公司 （於中華人民共和國註冊成立的股份有限公司） （股份代號：1276） 海外監管公告 本公告乃根據香港聯合交易所有限公司證券上市規則第13.10B條刊發。 根據中華人民共和國的有關法例規定，江蘇恒瑞醫藥股份有限公司（「本公司」）在 上海證券交易所網站( www.sse.com.cn )刊發了以下公告。茲載列如下，僅供參閱。 承董事會命 江蘇恒瑞醫藥股份有限公司 董事長 孫飄揚先生 中國上海 2025年8月20日 於本公告日期，董事會成員包括(i)執行董事孫飄揚先生、戴洪斌先生、馮佶女 士、張連山先生、江寧軍先生及孫杰平先生；(ii)非執行董事郭叢照女士；及(iii) 獨立非執行董事董家鴻先生、曾慶生先生、孫金雲先生及周紀恩先生。 江苏恒瑞医药股份有限公司 2025 年半年度报告 公司代码：600276 ...

Group 1 - The core point of the article is that Fujifilm (富士莱) has announced its collaboration with Hengrui Medicine (恒瑞医药) on an active pharmaceutical ingredient (API) project, which includes Eribulin and Apatinib Mesylate [1] Group 2 - The collaboration focuses on the development of specific APIs, indicating a strategic partnership in the pharmaceutical sector [1] - The mention of Eribulin and Apatinib Mesylate highlights the company's involvement in oncology-related drug development [1]

Core Viewpoint - Hengrui Medicine has successfully listed on the Hong Kong Stock Exchange, marking the largest pharmaceutical IPO in Hong Kong in nearly five years, with significant international investor interest and a total subscription amount of approximately HKD 41.31 billion, representing 41.77% of the total issuance scale [1][5][21]. Group 1: Company Overview - Hengrui Medicine, a leader in China's innovative pharmaceutical sector, has transformed from a small local manufacturer to a global player, now ranked among the top 50 pharmaceutical companies worldwide [4][10]. - The company has a rich history of over 55 years, witnessing significant growth and development in the pharmaceutical industry [4][22]. Group 2: Historical Development - From 1970 to 2003, Hengrui Medicine began as a small pharmaceutical factory, focusing on basic medicines, and achieved its first major success with the launch of the cancer drug Ifosfamide in 1995, leading to its status as a billion-yuan sales enterprise [5][6]. - Between 2004 and 2017, the company accelerated its transformation by establishing a research center in Shanghai and entering the high-value innovative drug development sector, achieving FDA certification for its products [6][7]. - From 2018 to 2022, Hengrui increased its R&D investment significantly, reaching CNY 6.346 billion in 2022, which accounted for 29.83% of its sales revenue, marking a historical high for the company [7][8]. Group 3: Recent Developments - Since 2023, Hengrui has shifted its focus from generic drugs to innovative drug development, with projected sales revenue from innovative drugs reaching CNY 13.892 billion in 2024, a year-on-year increase of 30.60% [9][12]. - The company has also engaged in 14 innovative drug licensing transactions since 2018, leading the domestic pharmaceutical industry in this area [9][12]. Group 4: Global Expansion Strategy - Hengrui is actively pursuing international markets, having initiated over 20 overseas clinical trials in regions such as the US, Europe, and Japan, and has completed 9 business development transactions in the past three years, with a cumulative transaction value of approximately USD 14 billion [18][21]. - The recent listing on the Hong Kong Stock Exchange is a strategic move to enhance its global brand influence and attract international investors, facilitating further international collaborations and business expansion [21][22].

Core Viewpoint - Heng Rui Medicine has shown significant growth and innovation in 2024, achieving record-high revenues and profits, while also advancing its internationalization strategy through successful licensing agreements and a planned IPO in Hong Kong [1][5][14]. Financial Performance - In 2024, Heng Rui Medicine reported revenue of 27.985 billion yuan, a year-on-year increase of 22.63%, and a net profit of 6.337 billion yuan, up 47.28% [5]. - For Q1 2025, the company achieved revenue of 7.206 billion yuan, reflecting a 20.14% year-on-year growth, with a net profit of 1.874 billion yuan, increasing by 36.9% [5]. Innovation and R&D - Heng Rui Medicine has invested a total of 46 billion yuan in R&D as of Q1 2025, with innovative drug sales accounting for over 50% of total revenue [4][5]. - The company has 19 approved new molecular entity drugs and over 90 innovative products in clinical development, with 400 clinical trials ongoing [6]. Licensing and Partnerships - In 2024, Heng Rui Medicine secured two major licensing agreements totaling nearly $2 billion, marking a significant expansion in its business development (BD) strategy [8][9]. - The company has completed 14 licensing agreements, with potential total transaction amounts reaching approximately $14 billion in the last three years [10][11]. Internationalization Strategy - Heng Rui Medicine is pursuing a dual strategy of "innovation + internationalization," with plans to issue H-shares in Hong Kong to fund R&D and commercialization efforts [13][14]. - The company aims to optimize its international cooperation model and explore partnerships with multinational pharmaceutical companies and innovative startups [12][15]. Leadership Changes - The appointment of Feng Ji as the new president is seen as a move to accelerate Heng Rui Medicine's innovation and internationalization strategies [16]. Future Outlook - With a robust pipeline of innovative drugs and an expanding international presence, Heng Rui Medicine is positioned to play a more significant role in the global pharmaceutical market [17].