（文章来源：证券日报） 证券日报网讯 1月9日，百克生物在互动平台回答投资者提问时表示，公司在研的阿尔茨海默病治疗性 疫苗，以国际上广泛认可的靶向Aβ和Tau蛋白进行抗原设计，旨在诱导机体产生针对Aβ和Tau的抗体， 以清除脑内产生的病理性Aβ和Tau蛋白，从而延缓疾病的进展。该项目正处于临床前研究阶段。 ...

Core Insights - The company, Baike Biotech (688276), focuses on innovative product research and development as its primary growth driver, leveraging over 20 years of technical expertise to establish a well-structured and diverse R&D pipeline [1] - Since 2025, Baike Biotech has reported significant progress in key projects, driven by a high proportion of R&D investment, contributing to the advancement of China's vaccine industry [1] R&D Strategy - Baike Biotech has established a tiered R&D strategy centered on "upgrading, filling gaps, and breakthroughs," aiming to create a product matrix that meets the health needs of the entire population [2] - The company focuses on optimizing mature products through process innovations to enhance safety and applicability, such as the acellular DTP vaccine, which reduces adverse reaction risks compared to traditional vaccines [2] - Baike Biotech targets unmet clinical needs in China with self-developed vaccines, like the "Ganwei" varicella-zoster virus vaccine, breaking the import monopoly and aiming to increase vaccination rates [2] - The company is also pursuing cutting-edge technologies with products like HSV-2 mRNA vaccine and Alzheimer's therapeutic vaccine, aligning with the national "Healthy China" strategy [2] Development Model - To ensure steady progress in its R&D strategy, Baike Biotech has implemented a "production, R&D, and reserve" model, covering the entire chain from mature product production to cutting-edge technology reserves [3] - Core products like varicella vaccine and nasal spray flu vaccine support the company's growth, while products in clinical stages include acellular DTP vaccine and adjuvanted flu vaccines [3] - The company has built a dual innovation system of "independent R&D + collaborative win-win," enhancing its technical strength through partnerships with universities and research institutions [3] Diverse Pipeline - Baike Biotech has established a diverse R&D pipeline with 13 vaccine projects and 3 monoclonal antibodies for infectious disease prevention, supported by five core technology platforms [4] - The company has achieved breakthroughs in traditional live attenuated vaccines and is advancing in mRNA vaccines and adjuvant technologies, with its self-developed adjuvant already applied in several vaccines [4] Key Projects - The company has developed a matrix of flu vaccines, including the nasal spray flu vaccine, which is the first and only one of its kind in China, offering significant advantages over traditional injected vaccines [5][6] - The "Ganwu" nasal spray flu vaccine has been approved for production and is undergoing clinical trials to expand its application to a broader age group [6] - Baike Biotech has also developed adjuvanted flu vaccines for elderly populations, enhancing immune response and safety [6] Innovative Vaccines - The HSV-2 mRNA vaccine aims to address the public health issue of genital herpes, currently in Phase I clinical trials, with no similar products available globally [7] - The DTP-Hib combined vaccine offers a "one shot, multiple protections" advantage, reducing the number of injections required for infants while ensuring high purity and consistency [8] - The Alzheimer's therapeutic vaccine is in preclinical research, showing promising safety and immunogenicity, with potential applications for early-stage patients [9]

Pharmaceutical and Biotechnology - Guangshengtang's innovative hepatitis B drug, Nairu Kewei GST-HG141, is currently undergoing active Phase III clinical trials [1] - Baike Biotech's Alzheimer's disease therapeutic vaccine is in the preclinical research stage [1] - Te Yi Pharmaceutical's acetaminophen tablets are suitable for symptoms related to chikungunya fever [1] Brain-Computer Interface - Jingxin Pharmaceutical has not yet entered the brain-computer interface technology field [1] - Sidik's products have not been applied in brain-computer interface electrodes or perception [1] Robotics - Feiyada's self-branded watch business has entered the Hainan duty-free channel [1] - Haineng Industrial's lawnmower orders are showing stable growth [1] - Chaojie Co., Ltd. has obtained small batch samples and formal small batch orders from clients including Zhiyuan Robotics [1] - Keda Intelligent's smart robotics-related products do not involve direct procurement and application of rare earth permanent magnet materials [1] - Lixing Co., Ltd.'s products can be applied in various rotating units required in the robotics field [1] - Digital China is a partner of Huawei Ascend [1] - Chiplink's AI glasses microphone chips and robotics laser radar chips have achieved breakthroughs [1] - Zhaolong Interconnect's data cables, high-speed cables, and connection products can be applied in 6G high-frequency transmission and underwater data centers [1] - Sanan Optoelectronics' Hunan Sanan SiC MOSFET products have been supplied in bulk to Delta and others [1] - Zhaowei Electromechanical's micro transmission and drive system products can be used in sweeping robots [1]