Core Viewpoint - The company, Jiudian Pharmaceutical, has won the bid for its core product, Loxoprofen Sodium Gel Patch, at the lowest price in the 11th national centralized procurement, which may pressure its gross margin in the short term, necessitating an increase in sales to cope with market competition [1] Business Strategy - The company has set a strategic goal for 2026 to drive growth through a dual approach of "stabilizing the existing business base and innovative transformation," ensuring sales of centralized procurement products in hospitals while expanding OTC channels and strengthening brand presence, as well as advancing the pipeline for innovative drug development [2] Product Development Progress - In the field of external preparations, the innovative drug JIJ02 gel is currently in the clinical stage, while the traditional Chinese medicine product, Jiao Qi Pain Relief Gel Patch, has been submitted for production approval. Unique products such as Ketoprofen Gel Patch and Daiwen Moxibustion Patch are prioritized for promotion [3] Company Status - The company plans to evaluate high-quality products or assets based on strategic needs and does not rule out acquisitions to enrich its product line. Additionally, it aims to establish a sustainable shareholder return plan based on operational performance and cash flow over the next 2-3 years [4]

Group 1: Company Overview - The company is Hunan Jiutian Pharmaceutical Co., Ltd., with stock code 300705 and bond code 123223 [1][2]. Group 2: Innovation and Product Development - The company is developing innovative external preparations, including the acne treatment JIJ02 gel, which is currently in clinical development [2]. - In the traditional Chinese medicine sector, the company has submitted production applications for the pepper pain relief gel patch and has received clinical trial approval for JIZM01 and JIZM02 [2][3]. - The company employs a dual approach of independent research and project introduction to enhance its innovative drug pipeline [2][4]. Group 3: Strategic Focus for 2026 - In 2026, the company aims to stabilize its existing business while driving innovation through a dual strategy [4]. - Key initiatives include promoting the sales of existing products like the Loxoprofen Sodium Gel Patch and enhancing brand recognition through the new "Jiutian Pain Relief Mr." branding [4]. - The company plans to expand into high-end pharmaceutical excipients while adhering to GMP management policies [4]. Group 4: Market Performance and Strategies - Despite a sluggish external market, the company has maintained stable growth in its external market by leveraging a professional OTC team of over 200 members [5]. - The company focuses on brand-driven strategies and patient education to enhance brand recognition and consumer loyalty [5]. - The integrated supply chain of "formulations + raw materials + pharmaceutical excipients" provides quality assurance and cost competitiveness [5]. Group 5: Acquisition Strategy - The company is open to evaluating and acquiring high-quality products or assets that align with its strategic development needs [7]. Group 6: Product Matrix - The company has established a clear and advantageous external product matrix, including products like Loxoprofen Sodium Gel Patch and Ketoprofen Gel Patch, which have significant competitive advantages [7]. - The Ketoprofen Gel Patch is a key exclusive product under medical insurance, while the traditional Chinese medicine sector features unique products like the Strong Waist and Bone Strengthening Patch [7].

编号：2026-02 | | 特定对象调研 □分析师会议 | | --- | --- | | 投资者关系活动 | □媒体采访 □业绩说明会 | | 类别 | □新闻发布会 □路演活动 | | | □现场参观 其他 | | 参与单位名称及 | 湖南医药基金、毅木资产、平安证券、长江证券、国信证券 | | 人员姓名 | 投资者代表共 9 人 | | 时间 | 2026 年 1 月 23 日下午 2:00-3:00 | | 地点 | 公司会议室 | | 上市公司接待人 | 副总经理兼董事会秘书：曾蕾 | | 员姓名 | 证券事务代表：甘荣 | | | 主要采用解答投资者提问的方式进行，主要问题回复如下： | | | 1、洛索洛芬钠凝胶贴膏集采后，什么时候执行？采购周期有 | | | 多长？ | | | 回复：据国家联采办的通知显示，第十一批国家集采中 | | | 选结果将于 2026 年 2 月在全国各地陆续落地执行。各地采购 | | 投资者关系活动 | 周期自中选结果执行之日起至 2028 年 12 月 31 日。 | | 主要内容介绍 | | | | 2、公司创新药 JIJ02 凝胶现阶段有哪些研发进展？ ...

Group 1: Company Overview and Strategy - Hunan Jiutian Pharmaceutical Co., Ltd. is focusing on expanding its market presence through a multi-channel strategy and brand enhancement initiatives, including the launch of the "Jiutian Zhen Tong Xian Sheng" branding campaign on December 6, 2025 [2][3] - The company aims to strengthen its product pipeline by increasing R&D investments and introducing new products, while also leveraging its integrated supply chain to control costs and ensure product quality [3][4] Group 2: Product Specifics and Market Response - The company’s key product, Loxoprofen Sodium Gel Patch, has been selected in the 11th round of national drug centralized procurement at prices of ¥17.88 for 4 patches, ¥26.82 for 6 patches, and ¥35.76 for 8 patches, with a total planned selection of approximately 30.12 million patches [5] - Following the price reduction from centralized procurement, the company anticipates a potential increase in sales volume for Loxoprofen Sodium Gel Patch, contingent on market conditions post-implementation [5] Group 3: Mergers and Acquisitions - The company has acquired a 67% stake in Hunan Nona Pharmaceutical Technology Co., Ltd., which includes 67 drug licenses, enhancing its product offerings and market stability [3][4] - This acquisition is expected to fill potential sales gaps from the centralized procurement of Loxoprofen Sodium Gel Patch and diversify the product range with unique offerings like the Daiwen Moxibustion Patch [3] Group 4: Innovation and R&D Focus - The company is transitioning towards innovative drug development, establishing multiple R&D centers and focusing on various drug forms and cooperative models to expedite the development of new drugs [4][6] - Current R&D efforts are concentrated on oncology and chronic disease treatments, utilizing small molecules, peptides, and other advanced drug forms to build a robust pipeline [4][6] Group 5: Future Product Development - The JIJ02 gel is expected to complete Phase I clinical trials in the first half of 2026, with plans to initiate Phase II trials thereafter [7] - The company is optimistic about the market prospects for Ketoprofen Gel, which was approved in 2023 and included in the national medical insurance directory, and is implementing new sales strategies to enhance market penetration [7]

Core Insights - Hunan Jiutian Pharmaceutical Co., Ltd. successfully won the bid for its core product, Loxoprofen Sodium Gel Patch, in the 11th national drug centralized procurement, with a total bid quantity of approximately 30.12 million patches across 11 provinces [2][3] - The company is undergoing a transformation towards innovative drugs, focusing on oncology and chronic diseases, with multiple R&D centers established to leverage regional advantages [4][5] - Jiutian Pharmaceutical is implementing a multi-faceted strategy to address market changes post-bid, including expanding its sales channels and enhancing its product pipeline through investments and acquisitions [3][4] Group 1: Bidding and Market Expectations - Jiutian Pharmaceutical's Loxoprofen Sodium Gel Patch was successfully selected in the centralized procurement at prices of 17.88 yuan for 4 patches, 26.82 yuan for 6 patches, and 35.76 yuan for 8 patches, with a total of 30.12 million patches to be supplied [2] - The company anticipates a potential increase in sales volume due to the growing demand in the chronic pain treatment market, although short-term profit margins may be pressured due to procurement requirements [2] Group 2: Response Strategies to Procurement Challenges - The company plans to enhance its sales strategy by focusing on outpatient markets and accelerating brand development while also investing in new product launches and pipeline expansion through acquisitions [3] - Jiutian Pharmaceutical emphasizes its integrated supply chain advantage, combining formulations, active pharmaceutical ingredients, and excipients to strengthen cost control and ensure product quality [3] Group 3: Innovative Drug Transformation and R&D Pipeline - Jiutian Pharmaceutical is adopting a strategy of multiple R&D centers and various drug forms to accelerate its innovative drug development, particularly in oncology and chronic diseases [4] - The company is planning to initiate Phase II clinical trials for its key project, JIJ02 gel, in the first half of 2026, while also implementing a share repurchase plan to align interests with its core team [5]

Group 1: Product Performance and Market Strategy - The company’s Loxoprofen Sodium Gel Patch was selected in the 11th batch of national drug centralized procurement with prices set at ¥17.88 for 4 patches, ¥26.82 for 6 patches, and ¥35.76 for 8 patches, with a planned selection quantity of 30.122605 million patches [2] - The company anticipates a certain growth in sales for the Loxoprofen Sodium Gel Patch post-price reduction due to the ongoing growth in the chronic pain treatment market, with actual performance feedback expected after next year's procurement execution [2][3] - The company plans to expand its sales channels and enhance brand building in response to the centralized procurement, leveraging its established multi-channel coverage system [4] Group 2: Financial Impact and Adjustments - The centralized procurement is expected to lead to a phase adjustment in profit margins for the Loxoprofen Sodium Gel Patch, impacting short-term revenue and profit performance [3] - The company is facing pressure to meet its annual targets due to market challenges, prompting a focus on promoting new products and enhancing market penetration through education and optimized product positioning [9] Group 3: Innovation and R&D Initiatives - The company is transitioning towards innovative drug development, establishing multiple R&D centers and focusing on various drug forms and collaboration models [5] - The R&D team consists of over 40 experts with experience in drug design and clinical research, focusing on oncology and chronic disease treatments using small molecules, peptides, and other drug forms [5] - The JIJ02 gel is expected to complete Phase I clinical trials in the first half of next year, with Phase II trials to follow [6] Group 4: Corporate Governance and Employee Engagement - The company is implementing a share repurchase plan to support future equity incentive programs, aiming to align the interests of the company, shareholders, and core team members [7]

Core Viewpoint - Hunan Jiutian Pharmaceutical Co., Ltd. is focusing on the transformation towards innovative drug development, with a significant increase in R&D investment and a stable operational performance in Q3 2025, despite challenges in the broader pharmaceutical industry [2][3]. Group 1: Q3 Operational Performance - The overall operational status in Q3 2025 remained stable, with market demand relatively consistent and sales progressing as planned [2]. - The pharmaceutical manufacturing industry saw a revenue of 12,275.2 billion yuan in the first half of 2025, a year-on-year decrease of 1.2%, and a profit total of 1,766.9 billion yuan, down 2.8% year-on-year [2]. - Despite industry pressures, the sales of medicated plaster in the terminal market showed a yearly increase, with sales expected to exceed 7 billion yuan in 2024, a growth of approximately 10%, and over 4 billion yuan in the first half of 2025, a growth of about 15% [2]. Group 2: Focus on Innovative Drug Transformation - The company is fully transitioning to focus on innovative drug R&D, with chemical innovative drugs as the core direction and some involvement in traditional Chinese medicine [3]. - Key therapeutic areas include pain management, focusing on polypeptide and small molecule drugs, and oncology, concentrating on PDC drug development [3]. - The company plans to invest between 250 million to 300 million yuan in R&D for 2025, indicating a strong commitment to its innovative transformation [3]. Group 3: Competitive Advantages and Market Strategies - The external pain relief market is expected to grow due to increasing health demands and an aging population, providing significant development space [4]. - The company aims to enhance product strength and brand influence in the gel plaster sector, optimizing product structure to meet diverse health needs [4]. - Specific product strategies include leveraging the advantages of JIJ02 gel for acne treatment and expanding indications in the polypeptide drug field, focusing on pain and pulmonary fibrosis [4]. - To address the impact of centralized procurement on key products like Loxoprofen Sodium Gel, the company plans to enhance sales through a comprehensive channel coverage system, increase R&D investment for new product launches, and strengthen cost control through an integrated supply chain [4].

Group 1: Company Overview and Market Conditions - The overall business operation of the company in Q3 2025 remains stable, with market demand relatively steady and sales progressing as planned [2] - The pharmaceutical manufacturing industry saw a revenue of CNY 12,275.2 billion in the first half of 2025, a year-on-year decrease of 1.2%, and a total profit of CNY 1,766.9 billion, down 2.8% [2] - Despite the overall industry pressure, the transdermal patch market is showing a positive growth trend, with sales expected to exceed CNY 7 billion in 2024, a year-on-year increase of approximately 10%, and over CNY 4 billion in the first half of 2025, up about 15% [3] Group 2: Strategic Focus and R&D Investment - The company is fully transitioning to focus on innovative drug research and development, with a core emphasis on chemical and traditional Chinese medicine innovations [4] - The estimated R&D expenditure for the year 2025 is projected to be between CNY 250 million and CNY 300 million [5] - The company is committed to enhancing its product strength and brand influence through continuous R&D, aiming to meet diverse health needs and create long-term value for investors [6][7] Group 3: Competitive Landscape and Product Development - The external pain relief market has significant growth potential, driven by increasing health demands and an aging population [6] - The JIJ02 gel shows advantages over existing acne treatments, such as lower risk of resistance and milder side effects, with plans to expand its indications in the peptide drug area [7] - Following the implementation of centralized procurement for the Loxoprofen Sodium Gel Patch, the company will adopt multi-faceted measures to stabilize its business foundation and ensure long-term growth [7]

Group 1 - The company is focusing on a strategic transformation towards innovative drug development, with a core emphasis on chemical innovative drugs and a layout for traditional Chinese medicine innovative drugs [2] - In the pain management sector, the company is developing peptide and small molecule drugs, while in the oncology sector, it is concentrating on PDC drugs [2] - The company has received clinical trial approval for JIZM01 and JIZM02, and has submitted production applications for the pepper seven pain relief gel patch [2] Group 2 - The company is optimistic about the market prospects for its anti-inflammatory and pain relief patch, primarily targeting the OTC channel, and plans to enhance sales through resource sharing and product matrix expansion [3] - The JIJ02 gel is expected to complete Phase I clinical trials by mid-next year and initiate Phase II trials, with characteristics that make it superior to existing acne treatments [4] - The company plans to expand the indications for peptide drugs and focus on new project introductions, particularly in pain and pulmonary fibrosis areas [4] Group 3 - The company is currently in the bidding phase for the eleventh batch of national drug procurement for its Loxoprofen sodium gel patch, with submission of application materials and public pricing due by October 27 [5] - The company’s e-commerce strategy is centered around the "big health category," utilizing social e-commerce platforms like Xiaohongshu, Douyin, and Kuaishou for targeted marketing [6]

Group 1: Company Strategy and Focus - The company is fully transforming to focus on innovative drug research and development, with a core emphasis on chemical and traditional Chinese medicine innovations [2][3] - Key therapeutic areas include pain management, with a focus on peptide and small molecule drugs, and oncology, specifically PDC drug development [2] - The company employs a dual approach of independent research and project acquisition to enhance its innovation capabilities and accelerate the commercialization of results [3] Group 2: Product Development and Market Outlook - The company has submitted production applications for its traditional Chinese medicine product, Jiao Qi Pain Relief Gel, which is currently under review [2] - The JIJ02 gel is expected to complete Phase I clinical trials in the first half of next year and will initiate Phase II trials thereafter [5] - The company is optimistic about the market potential for its anti-inflammatory pain relief patch, particularly due to the increasing prevalence of chronic pain among the aging population [4] Group 3: Market Strategy and Sales Channels - The sales strategy for the anti-inflammatory pain relief patch primarily targets OTC channels, with plans to enhance sales through resource sharing and product diversification [4] - The company is currently in the bidding phase for the 11th batch of national drug procurement, with submission of application materials and public pricing scheduled for October 27 [6] - The company plans to leverage e-commerce platforms like Xiaohongshu, Douyin, and Kuaishou to reach health-conscious consumers through content marketing and KOL collaborations [9]